A novel cell-based sensor detecting the activity of individual basic proprotein convertases.

Συγγραφείς: Löw, K., Hardes, K., Fedeli, C., Seidah, N.G., Constam, D.B., Pasquato, A., Steinmetzer, T., Roulin, A., Kunz, S.

Θεματικοί όροι: A549 Cells, Adaptor Proteins, Vesicular Transport/genetics, Vesicular Transport/metabolism, Biosensing Techniques/methods, Biosensing Techniques/standards, Drug Discovery/methods, Drug Discovery/standards, Enzyme Inhibitors/chemistry, Enzyme Inhibitors/pharmacology, Genes, Reporter, HEK293 Cells, HeLa Cells, High-Throughput Screening Assays/methods, High-Throughput Screening Assays/standards, Humans, Luciferases/genetics, Luciferases/metabolism, Peptidomimetics/chemistry, Peptidomimetics/pharmacology, Proprotein Convertases/antagonists & inhibitors, Proprotein Convertases/metabolism, Sensitivity and Specificity, furin, high-throughput screening, inhibitor, proprotein convertase, sensor

Relation: The FEBS Journal; https://iris.unil.ch/handle/iris/238829; serval:BIB_FB3BEDCEB392; 000477360500001

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/238829
https://doi.org/10.1111/febs.14979

A novel cell-based sensor detecting the activity of individual basic proprotein convertases.

Συγγραφείς: Löw, K., Hardes, K., Fedeli, C., Seidah, N.G., Constam, D.B., Pasquato, A., Steinmetzer, T., Roulin, A., Kunz, S.

Πηγή: The FEBS journal, vol. 286, no. 22, pp. 4597-4620

Θεματικοί όροι: A549 Cells, Adaptor Proteins, Vesicular Transport/genetics, Vesicular Transport/metabolism, Biosensing Techniques/methods, Biosensing Techniques/standards, Drug Discovery/methods, Drug Discovery/standards, Enzyme Inhibitors/chemistry, Enzyme Inhibitors/pharmacology, Genes, Reporter, HEK293 Cells, HeLa Cells, High-Throughput Screening Assays/methods, High-Throughput Screening Assays/standards, Humans, Luciferases/genetics, Luciferases/metabolism, Peptidomimetics/chemistry, Peptidomimetics/pharmacology, Proprotein Convertases/antagonists & inhibitors, Proprotein Convertases/metabolism, Sensitivity and Specificity, furin, high-throughput screening, inhibitor, proprotein convertase, sensor

Relation: info:eu-repo/semantics/altIdentifier/pmid/31276291; info:eu-repo/semantics/altIdentifier/eissn/1742-4658; https://serval.unil.ch/notice/serval:BIB_FB3BEDCEB392

Διαθεσιμότητα: https://serval.unil.ch/notice/serval:BIB_FB3BEDCEB392
https://doi.org/10.1111/febs.14979