Is France Once Again Looking for a Scapegoat?

Συγγραφείς: Lederman, MM, Flier, JS, Hale, P, Haase, AT, Powderly, W, Reiss, P, Silvestri, G, Sekaly, RP, Paiardini, M, Weissman, D, Kuritzkes, DR, Calabrese, LH, Agre, P, Reyes-Teran, G, Landay, AL, Lewin, S, Richman, DD, Volberding, P, Hunt, PW, Schechter, M

Relation: pii: pai.v6i2.490; https://hdl.handle.net/11343/305536

Διαθεσιμότητα: https://hdl.handle.net/11343/305536

Transgenic mice with muscle-specific insulin resistance develop increased adiposity, impaired glucose tolerance, and dyslipidemia

Συγγραφείς: Moller, DE, Author, Chang, PY, Author, Yaspelkis, BB, Author, Flier, JS, Author, WallbergHenriksson, H, Author, Ivy, JL, Author

Συνεισφορές: Moller, DE, Author, Chang, PY, Author, Yaspelkis, BB, Author, Flier, JS, Author, WallbergHenriksson, H, Author, Ivy, JL, Author

Πηγή: ENDOCRINOLOGY. 137(6):2397-2405

Σύνδεσμος πρόσβασης: https://ki.se/en/research/search-research-information?t=2&query=id%3A441905

Absence of CC Chemokine Ligand 2 Does Not Limit Obesity-Associated Infiltration of Macrophages Into Adipose Tissue

Συγγραφείς: Inouye, KE, Shi, H, Howard, JK, Daly, CH, Lord, GM, Rollins, BJ, Flier, JS

Πηγή: Inouye, K E, Shi, H, Howard, J K, Daly, C H, Lord, G M, Rollins, B J & Flier, J S 2007, 'Absence of CC Chemokine Ligand 2 Does Not Limit Obesity-Associated Infiltration of Macrophages Into Adipose Tissue', Diabetes, vol. 56, no. 9, pp. 2242-2250. https://doi.org/10.2337/db07-0425

Θεματικοί όροι: Male, 0301 basic medicine, insulin tolerance test, ITT, TNF-a, CCR, CC chemokine receptor, SOCS-3, tumor necrosis factor-a, Weight Gain, Mice, FACS, fluorescence-activated cell sorting, HIF-1a, Insulin, Chemokine CCL7, suppressor of cytokine signalling-3, Chemokine CCL2, Mice, Knockout, 2. Zero hunger, HIF-1a, hypoxia inducible factor-1a, 0303 health sciences, CCL, CC chemokine ligand, interleukin, Reverse Transcriptase Polymerase Chain Reaction, Immunohistochemistry, Monocyte Chemoattractant Proteins, iNOS, Adipose Tissue, iNOS, inducible nitric oxide synthase, KRH, SOCS-3, suppressor of cytokine signalling-3, FACS, hypoxia inducible factor-1a, 03 medical and health sciences, Animals, Obesity, CC chemokine receptor, ITT, insulin tolerance test, KRH, Krebs-Ringer HEPES, Macrophages, CCL, inducible nitric oxide synthase, MCP. monocyte chemoattractant protein, TNF-a, tumor necrosis factor-a, IL, Krebs-Ringer HEPES, CCR, IL, interleukin, CC chemokine ligand, Mice, Inbred C57BL, Energy Intake, fluorescence-activated cell sorting

Σύνδεσμος πρόσβασης: http://diabetes.diabetesjournals.org/content/56/9/2242.full.pdf
https://pubmed.ncbi.nlm.nih.gov/17473219

Attenuation of leptin and insulin signaling by SOCS proteins

Συγγραφείς: Howard, JK, Flier, JS

Πηγή: Trends in Endocrinology & Metabolism. 17:365-371

Θεματικοί όροι: Leptin, 2. Zero hunger, 0301 basic medicine, 0303 health sciences, Nuclear Proteins, Suppressor of Cytokine Signaling Proteins, Models, Biological, Receptor, Insulin, 03 medical and health sciences, Suppressor of Cytokine Signaling 1 Protein, Suppressor of Cytokine Signaling 3 Protein, Animals, Humans, Insulin, Receptors, Leptin, Signal Transduction

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/17010638

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3

Συγγραφείς: Howard, JK, Cave, BJ, Oksanen, LJ, Tzameli, I, Bjorbaek, C, Flier, JS

Πηγή: Nature Medicine. 10:734-738

Θεματικοί όροι: Blood Glucose, Leptin, 2. Zero hunger, 0301 basic medicine, 0303 health sciences, Receptors, Cell Surface, Suppressor of Cytokine Signaling Proteins, Dietary Fats, Mice, Inbred C57BL, Repressor Proteins, Mice, 03 medical and health sciences, Suppressor of Cytokine Signaling 3 Protein, Animals, Receptors, Leptin, Obesity, Energy Intake, Energy Metabolism, Transcription Factors

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/15220914

Cardiovascular Abnormalities in Transgenic Mice With Reduced Brown Fat: An Animal Model of Human Obesity

Συγγραφείς: CITTADINI, ANTONIO, MANTZOROS CS, HAMPTON TG, TRAVERS KE, KATZ SE, MORGAN JP, FLIER JS, DOUGLAS PS

Πηγή: Circulation. 100:2177-2183

Θεματικοί όροι: Male, 2. Zero hunger, Mice, Transgenic, Ventricular Function, Left, 3. Good health, Disease Models, Animal, Mice, 03 medical and health sciences, 0302 clinical medicine, Adipose Tissue, Brown, Echocardiography, Hypertension, Animals, Humans, Hypertrophy, Left Ventricular, Obesity

Σύνδεσμος πρόσβασης: https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.100.21.2177
https://pubmed.ncbi.nlm.nih.gov/10571977
http://hdl.handle.net/11588/137558
https://hdl.handle.net/11588/137558

Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects

Συγγραφείς: Maffei M, Stoffel M, Barone M, Moon B, Dammerman M, Ravussin E, Bogardus C, Ludwig DS, Flier JS, Talley M, Auerbach S, Friedman JM

Πηγή: Diabetes. 45:679-682

Θεματικοί όροι: Leptin, Male, 2. Zero hunger, 0301 basic medicine, Genomic Library, 0303 health sciences, Polymorphism, Genetic, Base Sequence, Molecular Sequence Data, Proteins, 3. Good health, Mice, 03 medical and health sciences, Oligodeoxyribonucleotides, Mutation, Diabetes Mellitus, Animals, Humans, Amino Acid Sequence, Obesity, Repetitive Sequences, Nucleic Acid

Σύνδεσμος πρόσβασης: http://diabetes.diabetesjournals.org/content/diabetes/45/5/679.full.pdf
https://pubmed.ncbi.nlm.nih.gov/8621022

alpha-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors

Συγγραφείς: Robins, SC, Stewart, I, Mcnay, DE, Taylor, V, Giachino, C, Goetz, M, Ninkovic, J, Briancon, N, Maratos-Flier, E, Flier, JS, Kokoeva, MV, Placzek, M

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://eprints.whiterose.ac.uk/78684/1/Alpha_Tanycytes.pdf
https://eprints.whiterose.ac.uk/id/eprint/78684/

Cardiovascular phenotype of transgenic mice with reduced brown fat

Συγγραφείς: CITTADINI, ANTONIO, MANTZOROS CS, HAMPTON TG, KATZ SE, TRAVERS KE, FLIER JS, MORGAN JP, DOUGLAS P.S.

Σύνδεσμος πρόσβασης: http://hdl.handle.net/11588/183018
https://hdl.handle.net/11588/183018

Leptin concentrations in relation to body mass index and the tumor necrosis factor-alpha system in humans

Συγγραφείς: Mantzoros, CS, Moschos, S, Avramopoulos, I, Kaklamani, V, Liolios, A, Doulgerakis, DE, Griveas, I, Katsilambros, N, Flier, JS

Πηγή: The Journal of clinical endocrinology and metabolism. 82(10)

Θεματικοί όροι: 2. Zero hunger, Adult, Leptin, Male, Adolescent, Tumor Necrosis Factor-alpha, Osmolar Concentration, Proteins, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Diabetes Mellitus, Type 2, Reference Values, Humans, Insulin, Female

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/9329377
https://pergamos.lib.uoa.gr/uoa/dl/object/3049656

Hormonal and Nutritional Regulation of PTRF in Adipose Tissue: Role of PTRF in Regulating Lipolysis.

Συγγραφείς: Aboulaich, N, primary, Maratos-Flier, E, additional, Flier, JS, additional

Πηγή: Posters IX. 2010/06/01

Immunology of Autoimmune Thyroid Diseases

Συγγραφείς: Strakosch, CR, Wenzel, BE, Row, VV, Volpe, R, Ingbar, SH, Amir, SM, Flier, JS, Segallblank, M, Einhorn, D

Πηγή: New England Journal of Medicine. 307:1499-1507

Θεματικοί όροι: T-Lymphocytes, Thyroid Gland, Receptors, Cell Surface, General & Internal, T-Lymphocytes, Regulatory, Thyroglobulin, Autoimmune Diseases, Major Histocompatibility Complex, Mice, 03 medical and health sciences, Medicine, General & Internal, 0302 clinical medicine, General & Internal Medicine, Microsomes, Animals, Humans, MEDICINE, GENERAL & INTERNAL, B-Lymphocytes, Thyroiditis, Autoimmune, Receptors, Thyrotropin, Thyroid Diseases, Graves Disease, 3. Good health, Immunoglobulin G, Cell Migration Inhibition, Medicine, Long-Acting Thyroid Stimulator

Σύνδεσμος πρόσβασης: https://espace.library.uq.edu.au/view/UQ:313483/UQ313483_OA.pdf
https://pubmed.ncbi.nlm.nih.gov/6292715
https://espace.library.uq.edu.au/view/UQ:313483/thumbnail_UQ313483_OA_t.jpg
https://espace.library.uq.edu.au/view/UQ:313483
https://espace.library.uq.edu.au/view/UQ:313483/UQ313483_OA.pdf
https://api.library.uq.edu.au/view/UQ:313483/UQ313483_OA.pdf
https://api.library.uq.edu.au/view/UQ:313483
https://api.library.uq.edu.au/view/UQ:313483/thumbnail_UQ313483_OA_t.jpg

Adipsin is an adipokine that improves β cell function in diabetes.

Συγγραφείς: Lo JC, Ljubicic S, Leibiger B, Kern M, Leibiger IB, Moede T, Kelly ME, Chatterjee Bhowmick D, Murano I, Cohen P, Banks AS, Khandekar MJ, Dietrich A, Flier JS, Blüher M, Danial NN, Berggren PO, Spiegelman B.M., CINTI, Saverio

Συνεισφορές: Lo, Jc, Ljubicic, S, Leibiger, B, Kern, M, Leibiger, Ib, Moede, T, Kelly, Me, Chatterjee Bhowmick, D, Murano, I, Cohen, P, Banks, A, Khandekar, Mj, Dietrich, A, Flier, J, Cinti, Saverio, Blüher, M, Danial, Nn, Berggren, Po, Spiegelman, B. M.

Περιγραφή αρχείου: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000340943100006; volume:158; issue:1; firstpage:41; lastpage:53; numberofpages:13; journal:CELL; https://hdl.handle.net/11566/223922

Διαθεσιμότητα: https://hdl.handle.net/11566/223922

Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells

Συγγραφείς: Kievit, P, Howard, JK, Badman, MK, Balthasar, N, Coppari, R, Mori, H, Lee, CE, Elmquist, JK, Yoshimura, A, Flier, JS

Πηγή: Kievit, P, Howard, JK, Badman, MK, Balthasar, N, Coppari, R, Mori, H, Lee, CE, Elmquist, JK, Yoshimura, A & Flier, JS 2006, 'Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells', Cell Metabolism, vol. 4, pp. 123 - 132. https://doi.org/10.1016/j.cmet.2006.06.010

Relation: info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1983/78f7b11b-b5b0-4e39-8bef-2a7c4d56fb1d

Διαθεσιμότητα: https://hdl.handle.net/1983/78f7b11b-b5b0-4e39-8bef-2a7c4d56fb1d
https://research-information.bris.ac.uk/en/publications/78f7b11b-b5b0-4e39-8bef-2a7c4d56fb1d
https://doi.org/10.1016/j.cmet.2006.06.010

Absence of mutations in the human OB gene in obese diabetic subjects

Συγγραφείς: Maffei, M, Stoffel, M, Barone, M, Moon, B, Dammerman, M, Ravussin, E, Bogardus, C, Ludwig, DS, Flier, JS, Talley, M, Auerbach, S, Friedman, JM

Πηγή: Diabetes (N.Y.N.Y.) 45 (1996): 679–682. doi:10.2337/diabetes.45.5.679 ; info:cnr-pdr/source/autori:Maffei, M; Stoffel, M; Barone, M; Moon, B; Dammerman, M; Ravussin, E; Bogardus, C; Ludwig, DS; Flier, JS; Talley, M; Auerbach, S; Friedman, JM/titolo:Absence of mutations in the human OB gene in obese diabetic subjects/doi:10.2337diabetes.45.5.679/rivista:Diabetes (N.Y.N.Y.)/anno:1996/pagina_da:679/pagina_a:682/intervallo_pagine:679–682/volume:45

Relation: info:cnr-pdr/author/matricola:11486/MAFFEI/MARGHERITA; http://www.cnr.it/prodotto/i/317990; https://publications.cnr.it/doc/317990; https://dx.doi.org/10.2337/diabetes.45.5.679; info:doi:10.2337/diabetes.45.5.679

Διαθεσιμότητα: http://www.cnr.it/prodotto/i/317990
https://publications.cnr.it/doc/317990
https://doi.org/10.2337/diabetes.45.5.679

Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin.

Συγγραφείς: Kershaw EE, Hamm JK, Verhagen LAW, Peroni O, Katic M, Flier JS, Kershaw, Erin E, Hamm, Jonathan K, Verhagen, Linda A W, Peroni, Odile, Katic, Masa, Flier, Jeffrey S

Πηγή: Diabetes; Jan2006, Vol. 55 Issue 1, p148-157, 10p

The stomach speaks -- ghrelin and weight regulation.

Συγγραφείς: Flier JS (AUTHOR), Maratos-Flier E (AUTHOR)

Πηγή: New England Journal of Medicine. 5/23/2002, Vol. 346 Issue 21, p1662-1663. 2p.

The hypothalamic arcuate nucleus and the control of peripheral substrates

Συγγραφείς: Joly-Amado, Aurélie, Cansell, Céline, Denis, Raphaël G.P., Delbes, Anne-Sophie, Castel, Julien, Martinez, Sarah, Luquet, Serge

Συνεισφορές: CANSELL, Celine, Unité de Biologie Fonctionnelle et Adaptative (BFA (UMR_8251 / U1133)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by young investigator ATIP grant from the CNRS, an equipment grant from the Région Île-de-France, an equipment grant from the University Paris Diderot-Paris 7, a research fellowship from the Société Francophone du Diabète-Lilly and the grant by the 'Agence Nationale de la Recherche' ANR-09-BLAN-0267-02 and ANR 11 BSV1 021 01. A.J-A. received a National Merit Scholarship from the French Department of National Education and Research, a research grant from the Société Francophone du Diabète and a research grant from the SFNEP-ANTADIR. R.D. received a research fellowship from the Région Île-de-France. C.C. received a PhD fellowship from the Centre National la Recherche Scientifique (CNRS) and a research grant from the Société Francophone du Diabète-Roche. 1 Molavi B, Rasouli N, Kern PA. The prevention and treatment of metabolic syndrome and high-risk obesity. Curr OpinCardiol 2006, 21:479–85. 2 Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000, 106:473–81. 3 Kopelman PG, Hitman GA. Diabetes. Exploding type II. Lancet 1998, 352(Suppl 4):SIV5. 4 Mokdad AH, Marks JS, Stroup DF, Actual causes of death in the United States, 2000. JAMA: J Am Med Assoc 2004, 291:1238–45. 5 Troy S, Soty M, Ribeiro L, Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypassbut not after gastric lap-band in mice. Cell Metab 2008, 8:201–11.Practice points Obesity and obesity-related disorders can be separated through central manipulation of ARCneurocircuitry. The establishment and activity of a hypothalamic network can define the equilibrium be-tween carbohydrate and lipid preference, ANR-09-BLAN-0267,gliodiabesity(2009)

Πηγή: Best Practice & Research Clinical Endocrinology & Metabolism. 28:725-737

Θεματικοί όροι: Neurons, 0301 basic medicine, 2. Zero hunger, 0303 health sciences, Pro-Opiomelanocortin, [SDV]Life Sciences [q-bio], Arcuate Nucleus of Hypothalamus, [SDV] Life Sciences [q-bio], Eating, 03 medical and health sciences, alpha-MSH, 11. Sustainability, Animals, Homeostasis, Humans, Agouti-Related Protein, Neuropeptide Y, Energy Metabolism

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/25256767

Leptin: 30 Years Later.

Συγγραφείς: Ahima RS; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Flier JS; Department of Physiology and Department of Medicine, Harvard Medical School, Boston, Masschusetts, USA; email: Jeffrey_Flier@hms.harvard.edu.

Πηγή: Annual review of physiology [Annu Rev Physiol] 2026 Feb; Vol. 88 (1), pp. 229-250. Date of Electronic Publication: 2025 Oct 03.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Annual Reviews Country of Publication: United States NLM ID: 0370600 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-1585 (Electronic) Linking ISSN: 00664278 NLM ISO Abbreviation: Annu Rev Physiol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Leptin*/physiology , Leptin*/deficiency , Leptin*/genetics , Leptin*/metabolism , Leptin*/therapeutic use, Obesity/physiopathology ; Obesity/metabolism ; Signal Transduction/physiology ; Receptors, Leptin/physiology ; Energy Metabolism/physiology ; Humans ; Animals ; Mice ; History, 21st Century

Politicizing science funding undermines public trust in science, academic freedom, and the unbiased generation of knowledge.

Συγγραφείς: Efimov IR; McCormick School of Engineering, Northwestern University, Chicago, IL, United States., Flier JS; Harvard Medical School, Boston, MA, United States., George RP; James Madison Program in American Ideals and Institutions, Princeton University, Princeton, NJ, United States., Krylov AI; Department of Chemistry, University of Southern California, Los Angeles, CA, United States., Maroja LS; Department of Biology, Williams College, Williamstown, MA, United States., Schaletzky J; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, United States., Tanzman J; Independent Consultant, Pasadena, CA, United States., Thompson A; Department of Mathematics, University of California, Davis, Davis, CA, United States.

Πηγή: Frontiers in research metrics and analytics [Front Res Metr Anal] 2024 Jul 23; Vol. 9, pp. 1418065. Date of Electronic Publication: 2024 Jul 23 (Print Publication: 2024).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Frontiers Country of Publication: Switzerland NLM ID: 101718019 Publication Model: eCollection Cited Medium: Internet ISSN: 2504-0537 (Electronic) Linking ISSN: 25040537 NLM ISO Abbreviation: Front Res Metr Anal Subsets: PubMed not MEDLINE