Unravelling the developmental origins of cystic fibrosis-related diabetes.

Authors: Cho A; McEwen Stem Cell Institute, University Health Network, Toronto, ON, Canada.; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Nostro MC; McEwen Stem Cell Institute, University Health Network, Toronto, ON, Canada. Cristina.Nostro@uhn.ca.; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Cristina.Nostro@uhn.ca.

Source: Diabetologia [Diabetologia] 2026 Aug; Vol. 69 (8), pp. 2131-2142. Date of Electronic Publication: 2026 Jun 09.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/complications , Cystic Fibrosis*/genetics , Cystic Fibrosis*/metabolism , Diabetes Mellitus*/etiology , Diabetes Mellitus*/metabolism , Diabetes Mellitus*/genetics, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Pancreas/metabolism ; Pancreas/embryology ; Mutation/genetics ; Humans ; Animals

Gastrointestinal and Pancreatic Manifestations of Cystic Fibrosis in the Era of Highly Effective Modulators.

Authors: Abi-Aad SJ; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, University of South Florida Morsani College of Medicine, 13101 Bruce B. Downs Boulevard, Tampa, FL 33612, USA., Narayanan S; Department of Pediatrics, University of South Florida Morsani College of Medicine, 13101 Bruce B. Downs Boulevard, Tampa, FL 33612, USA., Khalaf RT; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, University of South Florida Morsani College of Medicine, 13101 Bruce B. Downs Boulevard, Tampa, FL 33612, USA. Electronic address: khalafr@usf.edu.

Source: Advances in pediatrics [Adv Pediatr] 2026 Aug; Vol. 73 (1), pp. 179-190. Date of Electronic Publication: 2026 May 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1926 (Electronic) Linking ISSN: 00653101 NLM ISO Abbreviation: Adv Pediatr Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/complications , Cystic Fibrosis*/drug therapy , Cystic Fibrosis*/physiopathology , Gastrointestinal Diseases*/etiology , Gastrointestinal Diseases*/drug therapy , Gastrointestinal Diseases*/physiopathology, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Quinolones/therapeutic use ; Indoles/therapeutic use ; Benzodioxoles/therapeutic use ; Aminophenols/therapeutic use ; Isoxazoles/therapeutic use ; Pyrrolidines/therapeutic use ; Pyrazoles/therapeutic use ; Quinazolinones/therapeutic use ; Pyridines/therapeutic use ; Chloride Channel Agonists/therapeutic use ; Humans ; Drug Combinations ; Quinolines

Paradigm Shifts in Cystic Fibrosis Newborn Screening and Care in Infancy.

Authors: Wyatt ML; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Center for Respiratory Biology and Therapeutics, University of Washington, Seattle, WA, USA. Electronic address: mackenzielanwyatt@gmail.com., Clarion J; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA., McGarry M; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Center for Respiratory Biology and Therapeutics, University of Washington, Seattle, WA, USA.

Source: Advances in pediatrics [Adv Pediatr] 2026 Aug; Vol. 73 (1), pp. 161-178. Date of Electronic Publication: 2026 May 20.

Publication Type: Journal Article; Review

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1926 (Electronic) Linking ISSN: 00653101 NLM ISO Abbreviation: Adv Pediatr Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/diagnosis , Cystic Fibrosis*/therapy , Cystic Fibrosis*/genetics , Neonatal Screening*/methods, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Infant, Newborn ; Infant

Nintedanib increases BCL-2 in fibrotic fibroblasts, enhancing ABT-199 apoptosis and fibrosis resolution.

Authors: Cooley JC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, CO, United States.; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Penick SK; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, CO, United States., Wilson JA; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, United States., Javkhlan N; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, United States., Foster DG; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Edelman BL; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, United States., Schott CA; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Humphries SM; Department of Radiology, National Jewish Health, Denver, CO, United States., Lynch DA; Department of Radiology, National Jewish Health, Denver, CO, United States., Schwartz DA; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.; Department of Research, Veterans Administration Eastern Colorado Healthcare System, Aurora, CO, United States., Riches DWH; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, United States.; Department of Research, Veterans Administration Eastern Colorado Healthcare System, Aurora, CO, United States., Redente EF; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, United States.; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Source: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2026 Aug 01; Vol. 74 (8), pp. 1103-1113.

Publication Type: Journal Article

Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

MeSH Terms: Indoles*/pharmacology , Apoptosis*/drug effects , Fibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/pathology , Sulfonamides*/pharmacology , Proto-Oncogene Proteins c-bcl-2*/metabolism , Bridged Bicyclo Compounds, Heterocyclic*/pharmacology , Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/metabolism, Lung/pathology ; Lung/drug effects ; Lung/metabolism ; Idiopathic Pulmonary Fibrosis/drug therapy ; Animals ; Mice ; Mice, Inbred C57BL ; Humans ; Bleomycin ; Male

Developmental dynamics of ovine lung in health and cystic fibrosis at single-cell resolution.

Authors: Tkachenko S; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Leir SH; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Van Wettere AJ; Department of Veterinary Clinical and Life Sciences, Utah State University, Logan, UT, USA., Perisse IV; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Mustafa Y; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Marriott CM; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Patrick T; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Liu Y; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., White KL; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Polejaeva IA; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Harris A; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA. ann.harris@case.edu.

Source: Functional & integrative genomics [Funct Integr Genomics] 2026 Jul 31; Vol. 26 (1). Date of Electronic Publication: 2026 Jul 31.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE

MeSH Terms: Lung*/metabolism , Lung*/growth & development , Lung*/embryology , Lung*/pathology , Cystic Fibrosis*/genetics , Cystic Fibrosis*/pathology , Cystic Fibrosis*/metabolism, Sheep/genetics ; Sheep/growth & development ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Animals ; Single-Cell Analysis ; Female ; Mutation

Atg5 deficiency alters myofibroblast accumulation and alveolar regeneration in lung fibrosis.

Authors: Li X; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Xu G; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Wang Q; Department of Stomatology, Haihe Hospital, Tianjin University, Tianjin 300350, China., Ma Q; Department of Laboratory Medicine, Tianjin Hospital, Tianjin University, Tianjin 300350, China., Liu X; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Li H; Department of Respiratory and Critical Care, Haihe Hospital, Tianjin University, Tianjin 300350, China., Wang S; Department of Respiratory, Tianjin Union Medical Center, Nankai University, Tianjin 300121, China., Liu Y; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Jin Y; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, China., Miao X; Department of Basic Medicine, Haihe Clinical School, Tianjin Medical University, Tianjin 300350, China., He Z; Department of Basic Medicine, Haihe Clinical School, Tianjin Medical University, Tianjin 300350, China., Dong J; Academy of Medical Engineering and Translational Medicine, School of Medicine, Tianjin University, Tianjin 300072, China., Li K; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Wang J; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Li Y; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Zhang Q; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China., Jiang D; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Wu J; Tianjin Institute of Respiratory Diseases, Tianjin 300350, China. Electronic address: wujp0618@126.com., Ning W; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, China. Electronic address: ningwen108@nankai.edu.cn., Chen H; Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin 300350, China; Tianjin Institute of Respiratory Diseases, Tianjin 300350, China. Electronic address: huaiyong.chen@foxmail.com.

Source: Stem cell reports [Stem Cell Reports] 2026 Jul 14; Vol. 21 (7), pp. 102979. Date of Electronic Publication: 2026 Jul 02.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

MeSH Terms: Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Autophagy-Related Protein 5*/deficiency , Autophagy-Related Protein 5*/genetics , Autophagy-Related Protein 5*/metabolism , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/metabolism , Pulmonary Fibrosis*/genetics , Pulmonary Alveoli*/pathology , Pulmonary Alveoli*/metabolism , Regeneration*, Transforming Growth Factor beta1/metabolism ; Alveolar Epithelial Cells/metabolism ; Idiopathic Pulmonary Fibrosis/pathology ; Idiopathic Pulmonary Fibrosis/metabolism ; Animals ; Cell Differentiation ; Humans ; Mice ; Bleomycin ; Oxidative Stress ; Cell Proliferation ; Cellular Senescence

Cancer-associated and non-neoplastic fibrosis: Comparative mechanisms and emerging antifibrotic strategies.

Authors: Riccò B; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; Division of Oncology, Department of Oncology and Haematology, Modena AOU - Hospital, Modena, Italy; Department of Oncology, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy. Electronic address: beatrice.ricco3@gmail.com., Grisendi G; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy., Monaco AL; Rheumatology Unit, AOU S. Anna, Ferrara, Italy., Giuggioli D; Rheumatology Unit, Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy., Clini E; Lung and Respiratory Intensive Care Unit, Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy., Dominici M; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; Division of Oncology, Department of Oncology and Haematology, Modena AOU - Hospital, Modena, Italy. Electronic address: massimo.dominici@unimore.it.

Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119626. Date of Electronic Publication: 2026 Jun 07.

Publication Type: Journal Article; Review

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH Terms: Antifibrotic Agents*/therapeutic use , Antifibrotic Agents*/pharmacology , Cancer-Associated Fibroblasts*/pathology , Cancer-Associated Fibroblasts*/metabolism , Cancer-Associated Fibroblasts*/drug effects , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Neoplasms*/pathology , Neoplasms*/drug therapy , Neoplasms*/metabolism, Extracellular Matrix/metabolism ; Extracellular Matrix/pathology ; Extracellular Matrix/drug effects ; Fibrosis/drug therapy ; Animals ; Humans ; Signal Transduction

Investigation of HE4 expression concerning epithelial-mesenchymal transition (EMT) in cystic fibrosis epithelial cells.

Authors: Pócsi M; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Balla GJ; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Fenyvesi F; Department of Molecular and Nanopharmaceutics, Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary., Rusznyák Á; Department of Molecular and Nanopharmaceutics, Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary., Fejes Z; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Balogh I; Division of Clinical Genetics, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Macek M Jr; Department of Biology and Medical Genetics, 2nd Faculty of Medicine and Motol University Hospital, Charles University, Prague, Czech Republic., Amaral MD; BioISI- Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Nagy B Jr; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary. Electronic address: nagyb80@gmail.com.

Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2026 Jul; Vol. 25 (4), pp. 735-744. Date of Electronic Publication: 2026 Apr 05.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/genetics , Cystic Fibrosis*/genetics , Cystic Fibrosis*/metabolism , Cystic Fibrosis*/pathology , Epithelial Cells*/metabolism , Epithelial Cells*/pathology , Proteins*/metabolism , WAP Four-Disulfide Core Domain Protein 2*, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Matrix Metalloproteinase 9/metabolism ; Humans

Lumacaftor-Ivacaftor in Pediatric Patients With Cystic Fibrosis and Advanced Liver Disease: A Pilot Study.

Authors: Lim AYL; Department of Respiratory and Sleep Medicine, Queensland Children's Hospital, Brisbane, Queensland, Australia; University of Queensland Centre for Clinical Research, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia. Electronic address: adeline.lim@health.qld.gov.au., Hernández-Mitre MP; University of Queensland Centre for Clinical Research, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia., Lewindon PJ; Department of Gastroenterology, Queensland Children's Hospital, Brisbane, Queensland, Australia., Roberts JA; University of Queensland Centre for Clinical Research, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia; Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; Herston Infectious Diseases Institute (HeIDI), Metro North Health, Brisbane, Queensland, Australia; UR UM 103, University of Montpellier, Division of Anesthesia Critical Care and Emergency and Pain Medicine, Nimes University Hospital, Nimes, France., Schneider-Futschik EK; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria, Australia., Wainwright CE; Department of Respiratory and Sleep Medicine, Queensland Children's Hospital, Brisbane, Queensland, Australia; University of Queensland Centre for Clinical Research, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia.

Source: Clinical therapeutics [Clin Ther] 2026 Jun; Vol. 48 (6), pp. 534-538. Date of Electronic Publication: 2026 Apr 23.

Publication Type: Journal Article

Journal Info: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/drug therapy , Cystic Fibrosis*/complications , Aminophenols*/pharmacokinetics , Aminophenols*/therapeutic use , Aminophenols*/adverse effects , Aminophenols*/administration & dosage , Benzodioxoles*/pharmacokinetics , Benzodioxoles*/therapeutic use , Benzodioxoles*/adverse effects , Benzodioxoles*/administration & dosage , Quinolones*/pharmacokinetics , Quinolones*/therapeutic use , Quinolones*/adverse effects , Quinolones*/administration & dosage , Aminopyridines*/pharmacokinetics , Aminopyridines*/therapeutic use , Aminopyridines*/adverse effects , Aminopyridines*/administration & dosage , Liver Diseases*/drug therapy , Liver Diseases*/etiology, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Child ; Pilot Projects ; Adolescent ; Male ; Female ; Drug Combinations ; Child, Preschool ; Liver Function Tests

Single-cell profiling of BAL in preschool cystic fibrosis reveals macrophage dysregulation and ivacaftor-modified inflammatory programs in the early life lung.

Authors: Maksimovic J; Computational Biology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia; Respiratory Diseases, Murdoch Children's Research Institute, Parkville, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Shanthikumar S; Respiratory Diseases, Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Respiratory and Sleep Medicine, Royal Children's Hospital, Parkville, VIC, Australia., Howitt G; Computational Biology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Dixit G; Computational Biology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Hickey PF; Cellular Genomics Projects Team, Advanced Technology and Biology Division, WEHI, Parkville, VIC, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Anttila C; Cellular Genomics Projects Team, Advanced Technology and Biology Division, WEHI, Parkville, VIC, Australia., Brown DV; Cellular Genomics Projects Team, Advanced Technology and Biology Division, WEHI, Parkville, VIC, Australia., Gubbels L; Respiratory Diseases, Murdoch Children's Research Institute, Parkville, VIC, Australia., Senabouth A; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, NSW, Australia., Amann-Zalcenstein D; Cellular Genomics Projects Team, Advanced Technology and Biology Division, WEHI, Parkville, VIC, Australia., Powell JE; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, NSW, Australia., Ranganathan SC; Respiratory Diseases, Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Respiratory and Sleep Medicine, Royal Children's Hospital, Parkville, VIC, Australia., Oshlack A; Computational Biology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia; School of Mathematics and Statistics, University of Melbourne, Parkville, VIC, Australia., Neeland MR; Respiratory Diseases, Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia. Electronic address: melanie.neeland@mcri.edu.au.

Source: Mucosal immunology [Mucosal Immunol] 2026 Jun; Vol. 19 (3), pp. 100338. Date of Electronic Publication: 2026 Mar 30.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE

MeSH Terms: Quinolones*/therapeutic use , Quinolones*/pharmacology , Macrophages*/immunology , Macrophages*/drug effects , Cystic Fibrosis*/drug therapy , Cystic Fibrosis*/immunology , Aminophenols*/therapeutic use , Aminophenols*/pharmacology , Lung*/immunology , Lung*/pathology , Bronchoalveolar Lavage Fluid*/cytology , Bronchoalveolar Lavage Fluid*/immunology, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Humans ; Child, Preschool ; Single-Cell Analysis ; Female ; Transcriptome ; Single-Cell Gene Expression Analysis ; Male ; Gene Expression Profiling ; Inflammation

Long-term therapy with elexacaftor/tezacaftor/ivacaftor improves cystic fibrosis lung disease and monocyte function.

Authors: Sangiorgi G; Department of Biology and Biotechnology 'C. Darwin' Sapienza University, Rome, Italy., Cavinato L; Department of Molecular Microbiology, Washington University in St Louis, Missouri, USA., Cristoferi M; Department of Biology and Biotechnology 'C. Darwin' Sapienza University, Rome, Italy., Chiappetta D; Department of Basic and Applied Sciences for Engineering, Sapienza University, Rome, Italy., Pastore V; Department of Biology and Biotechnology 'C. Darwin' Sapienza University, Rome, Italy., Cimino G; Regional Cystic Fibrosis Center, AOU Policlinico Umberto I - Sapienza University, Rome, Italy., Cimino L; Regional Cystic Fibrosis Center, AOU Policlinico Umberto I - Sapienza University, Rome, Italy., Ascenzioni F; Department of Biology and Biotechnology 'C. Darwin' Sapienza University, Rome, Italy., Del Porto P; Department of Biology and Biotechnology 'C. Darwin' Sapienza University, Rome, Italy. Electronic address: paola.delporto@uniroma1.it.

Source: Respiratory medicine [Respir Med] 2026 Aug-Sep; Vol. 260, pp. 108930. Date of Electronic Publication: 2026 Jun 04.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE

MeSH Terms: Monocytes*/drug effects , Monocytes*/metabolism , Monocytes*/physiology , Cystic Fibrosis*/drug therapy , Cystic Fibrosis*/physiopathology , Cystic Fibrosis*/microbiology , Aminophenols*/therapeutic use , Aminophenols*/pharmacology , Indoles*/therapeutic use , Indoles*/pharmacology , Indoles*/administration & dosage , Benzodioxoles*/therapeutic use , Benzodioxoles*/pharmacology , Quinolones*/therapeutic use , Quinolones*/pharmacology , Quinolones*/administration & dosage , Pyridines*/therapeutic use , Pyridines*/pharmacology , Pyrazoles*/therapeutic use , Pyrrolidines*/therapeutic use , Pyrroles*/therapeutic use, Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Phagocytosis/drug effects ; Pseudomonas aeruginosa/drug effects ; RNA, Messenger/metabolism ; Pseudomonas Infections/drug therapy ; Chloride Channel Agonists/therapeutic use ; Humans ; Female ; Male ; Drug Combinations ; Adult ; Young Adult ; Quinolines

Long-term clinical outcomes of neonatal cystic fibrosis presentation: a single-center retrospective study.

Authors: Freitas E; Pediatric Pulmonology Unit, ULS São José, Hospital Dona Estefânia, Lisbon, Portugal. ema.coelho@ulssjose.min-saude.pt.; Department of Pediatrics, Hospital Dona Estefânia, Lisbon, Portugal. ema.coelho@ulssjose.min-saude.pt., Simão C; Pediatric Pulmonology Unit, ULS São José, Hospital Dona Estefânia, Lisbon, Portugal.; Department of Pediatrics, Hospital Divino Espírito Santo, Ponta Delgada, Portugal., de Bragança RL; Pediatric Pulmonology Unit, ULS São José, Hospital Dona Estefânia, Lisbon, Portugal.; Cystic Fibrosis Reference Center, ULS São José, Hospital Dona Estefânia, Lisbon, Portugal., Castanhinha S; Pediatric Pulmonology Unit, ULS São José, Hospital Dona Estefânia, Lisbon, Portugal.; Cystic Fibrosis Reference Center, ULS São José, Hospital Dona Estefânia, Lisbon, Portugal.

Source: European journal of pediatrics [Eur J Pediatr] 2026 Jul 16; Vol. 185 (8). Date of Electronic Publication: 2026 Jul 16.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/complications , Cystic Fibrosis*/diagnosis , Cystic Fibrosis*/genetics , Cystic Fibrosis*/mortality , Meconium Ileus*/etiology, Exocrine Pancreatic Insufficiency/etiology ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Retrospective Studies ; Female ; Male ; Infant, Newborn ; Prognosis ; Portugal ; Adolescent ; Infant ; Neonatal Screening

Targeting the RNA acetyltransferase NAT10 attenuates pulmonary fibrosis via the ac4C-mediated regulation of the C/EBPβ-ITGA11 axis.

Authors: Wang Z; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Wu Q; Department of Respiratory and Critical Care Medicine, Jinling Hospital, the Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Yao Y; Department of Pulmonary and Critical Care Medicine, Nanjing Second Hospital, Nanjing University of Chinese Medicine, Nanjing, China., Cao M; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Ding J; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Xiao Y; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Huang X; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China; School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: huangxm2017@pku.edu.cn., Luo J; Department of Cardiothoracic Surgery, Jinling Hospital, the Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. Electronic address: luojing_2767983@163.com.

Source: International immunopharmacology [Int Immunopharmacol] 2026 Jul 15; Vol. 181, pp. 116793. Date of Electronic Publication: 2026 May 05.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: CCAAT-Enhancer-Binding Protein-beta*/metabolism , CCAAT-Enhancer-Binding Protein-beta*/genetics , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , N-Terminal Acetyltransferase E*/metabolism , N-Terminal Acetyltransferase E*/antagonists & inhibitors , N-Terminal Acetyltransferase E*/genetics , Integrin alpha Chains*/metabolism , Integrin alpha Chains*/genetics, Fibroblasts/drug effects ; Lung/pathology ; Lung/drug effects ; Cytidine/metabolism ; Cytidine/analogs & derivatives ; Animals ; Humans ; Bleomycin ; Mice ; Mice, Inbred C57BL ; Male ; Pulmonary Fibrosis ; Benzoates ; Nitrobenzenes ; Pyrazolones ; N-Terminal Acetyltransferases

When viruses meet cystic fibrosis: Insights into host-pathogen dynamics.

Authors: Lotti V; Microbiology Section, Department of Diagnostics and Public Health, University of Verona, Verona, Italy., Lagni A; Microbiology Section, Department of Diagnostics and Public Health, University of Verona, Verona, Italy., Diani E; Microbiology Section, Department of Diagnostics and Public Health, University of Verona, Verona, Italy., Palmisano A; Microbiology Section, Department of Diagnostics and Public Health, University of Verona, Verona, Italy., Cecchetto R; Microbiology Section, Department of Diagnostics and Public Health, University of Verona, Verona, Italy. Electronic address: riccardo.cecchetto@univr.it., Tonon E; UOC Microbiology and Virology, AOUI Verona, Verona, Italy., Sorio C; General Pathology Section, Department of Medicine, University of Verona, Verona, Italy., Gibellini D; Microbiology Section, Department of Diagnostics and Public Health, University of Verona, Verona, Italy; UOC Microbiology and Virology, AOUI Verona, Verona, Italy.

Source: Microbiological research [Microbiol Res] 2026 Jul; Vol. 308, pp. 128508. Date of Electronic Publication: 2026 Mar 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: G. Fischer Country of Publication: Germany NLM ID: 9437794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0623 (Electronic) Linking ISSN: 09445013 NLM ISO Abbreviation: Microbiol Res Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/virology , Cystic Fibrosis*/complications , Virus Diseases*/virology , Virus Diseases*/complications , Virus Diseases*/epidemiology , Respiratory Tract Infections*/virology , Host-Pathogen Interactions*, Viruses/pathogenicity ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans

A disrupted microbial network and an ecological shift towards anaerobes in NTM-infected cystic fibrosis patients.

Authors: Pailhoriès H; Univ Brest, INSERM, EFS, UMR 1078, GGB - Brest France., Velo-Suarez L; Univ Brest, INSERM, EFS, UMR 1078, GGB - Brest France; Brest Center for Microbiota Analysis (CBAM), Brest University Hospital - Brest France., Moalic Y; Brest Center for Microbiota Analysis (CBAM), Brest University Hospital - Brest France., Alcoforado-Diniz J; Univ Brest, INSERM, EFS, UMR 1078, GGB - Brest France., Gouriou S; Univ Brest, INSERM, EFS, UMR 1078, GGB - Brest France., Bessou A; French Cystic Fibrosis Registry, Vaincre la Mucoviscidose, Paris France., Cambau E; Université Paris Cité, IAME, Inserm UMR 1137, Service de mycobactériologie spécialisée et de référence, Laboratoire associé du CNR des mycobactéries et de la résistance des mycobactéries aux antituberculeux (CNR-MyRMA), AP-HP GHU Paris Nord, Hôpital Bichat, Paris, France., Burgel PR; Respiratory Medicine and National Cystic Fibrosis Reference Center, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Institut Cochin, INSERM, CNRS, U1016 - Paris France., Herrmann JL; Univ Paris-Saclay, UVSQ, INSERM, Infection and Inflammation - Montigny-Le-Bretonneux France; AP-HP, Groupe Hospitalo-Universitaire Paris-Saclay, Hôpital Raymond Poincaré - Garches France., Héry-Arnaud G; Univ Brest, INSERM, EFS, UMR 1078, GGB - Brest France; Brest Center for Microbiota Analysis (CBAM), Brest University Hospital - Brest France; Department of Infectious Agents, Brest University Hospital - Brest France. Electronic address: hery@univ-brest.fr.

Corporate Authors: CIMeNT Study Group

Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2026 Jul; Vol. 25 (4), pp. 655-663. Date of Electronic Publication: 2026 Apr 28.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/microbiology , Cystic Fibrosis*/complications , Cystic Fibrosis*/physiopathology , Mycobacterium Infections, Nontuberculous*/microbiology , Mycobacterium Infections, Nontuberculous*/diagnosis , Bacteria, Anaerobic*/isolation & purification, Sputum/microbiology ; RNA, Ribosomal, 16S/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Male ; Microbiota ; Female

Microbiological outcomes associated with Burkholderia species in people with cystic fibrosis receiving CFTR modulator therapy.

Authors: Riddles T; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia; Faculty of Medicine, University of Queensland, QLD, Brisbane, Australia., Smith D; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia; Faculty of Medicine, University of Queensland, QLD, Brisbane, Australia., Reid DW; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia; Faculty of Medicine, University of Queensland, QLD, Brisbane, Australia; Lung Inflammation & Infection, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Henderson D; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia., Blanco AJ; Department of Microbiology, Royal Brisbane Women's Hospital, Brisbane, QLD, Australia., Moore V; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia., Wood M; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia., Evans IES; Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane, QLD, Australia; Faculty of Medicine, University of Queensland, QLD, Brisbane, Australia. Electronic address: ieuan.evans@uq.edu.au.

Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2026 Jul; Vol. 25 (4), pp. 637-642. Date of Electronic Publication: 2026 Mar 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/drug therapy , Cystic Fibrosis*/microbiology , Cystic Fibrosis*/complications , Burkholderia Infections*/microbiology , Burkholderia Infections*/drug therapy , Burkholderia Infections*/epidemiology , Burkholderia cepacia complex*/isolation & purification , Burkholderia*/isolation & purification, Indoles/therapeutic use ; Benzodioxoles/therapeutic use ; Quinolones/therapeutic use ; Pyrazoles/therapeutic use ; Pyridines/therapeutic use ; Aminophenols/therapeutic use ; Humans ; Cystic Fibrosis Transmembrane Conductance Regulator ; Drug Combinations

Fetal Transplacental Therapy to Mitigate Consequences of Cystic Fibrosis.

Authors: Kam CW; Department of Pharmacy, University of North Carolina Hospitals, Chapel Hill, North Carolina., McKinzie CJ; Department of Pharmacy, University of North Carolina Hospitals, Chapel Hill, North Carolina., Goralski JL; Division of Pediatric Pulmonology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Division of Pulmonary/Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: Jennifer_goralski@med.unc.edu.

Source: Clinical therapeutics [Clin Ther] 2026 Jul; Vol. 48 (7), pp. 571-582. Date of Electronic Publication: 2026 Mar 13.

Publication Type: Journal Article; Review

Journal Info: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/therapy , Cystic Fibrosis*/drug therapy , Cystic Fibrosis*/genetics , Aminophenols*/therapeutic use , Aminophenols*/administration & dosage , Benzodioxoles*/therapeutic use , Benzodioxoles*/administration & dosage , Fetal Therapies*/methods, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Female ; Pregnancy ; Maternal-Fetal Exchange

RUNX1 is a mediator of fibrotic activation and epigenetic memory in lung fibroblasts.

Authors: Gilbert RM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Jones DL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Wellmerling J; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Caporarello N; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.; Department of Medicine, Stritch School of Medicine, Loyola University Chicago, Chicago, IL, United States., Meridew JA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Choi KM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Haak AJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Link PA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Tan Q; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.; The Hormel Institute, University of Minnesota, Austin, MN, United States., Lee JH; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Ordog T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States., Ligresti G; Department of Medicine, Boston University School of Medicine, Boston, MA, United States., Tschumperlin DJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.

Source: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2026 Jul 01; Vol. 74 (7), pp. 911-923.

Publication Type: Journal Article

Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

MeSH Terms: Core Binding Factor Alpha 2 Subunit*/metabolism , Core Binding Factor Alpha 2 Subunit*/genetics , Fibroblasts*/metabolism , Fibroblasts*/pathology , Lung*/pathology , Lung*/metabolism , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/genetics , Pulmonary Fibrosis*/metabolism , Epigenesis, Genetic*, Mesoderm/metabolism ; Mesoderm/pathology ; Mesenchymal Stem Cells/metabolism ; Animals ; Epigenetic Memory ; Mice ; Mice, Inbred C57BL ; Fibrosis ; Cells, Cultured

Clinical features associated with Pseudomonas aeruginosa colonization in children under 2 years of age: a retrospective study of Cystic Fibrosis Registry.

Authors: Ocak E; Department of Pediatric Pulmonology, Ministry of Health Ankara City Hospital, Ankara, Türkiye., Cinel G; Department of Pediatric Pulmonology, Ministry of Health Ankara City Hospital, Ankara, Türkiye., Tuğcu GD; Department of Pediatric Pulmonology, Ministry of Health Ankara City Hospital, Ankara, Türkiye., Polat SE; Department of Pediatric Pulmonology, Ministry of Health Ankara City Hospital, Ankara, Türkiye., Tural DA; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Özsezen B; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Yalçın E; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Kiper N; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Şen V; Department of Pediatric Pulmonology, Faculty of Medicine, Dicle University, Diyarbakır, Türkiye., Şen HS; Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakır, Türkiye., Altıntaş DU; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Çukurova University, Adana, Türkiye., Kılınç AA; Department of Pediatric Pulmonology, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Türkiye., Çokuğraş H; Department of Pediatric Pulmonology, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Türkiye., Yazan H; Department of Pediatric Pulmonology, Faculty of Medicine, Bezmialem Vakıf University, İstanbul, Türkiye., Ünal G; Department of Pediatric Pulmonology, Meram Medicine Faculty, Necmettin Erbakan University, Konya, Türkiye., Yılmaz Aİ; Department of Pediatric Pulmonology, Meram Medicine Faculty, Necmettin Erbakan University, Konya, Türkiye., Irmak I; Department of Chest Diseases, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Damadoğlu E; Department of Chest Diseases, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Öztürk GK; Department of Pediatric Pulmonology, Faculty of Medicine, Ege University, İzmir, Türkiye., Demir E; Department of Pediatric Pulmonology, Faculty of Medicine, Ege University, İzmir, Türkiye., Başaran E; Department of Pediatric Pulmonology, Faculty of Medicine, Akdeniz University, Antalya, Türkiye., Bingöl A; Department of Pediatric Pulmonology, Faculty of Medicine, Akdeniz University, Antalya, Türkiye., Sapan N; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Bursa Uludağ University, Bursa, Türkiye., Canıtez Y; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Bursa Uludağ University, Bursa, Türkiye., Asfuroğlu P; Department of Pediatric Pulmonology, Faculty of Medicine, Gazi University, Ankara, Türkiye., Aslan AT; Department of Pediatric Pulmonology, Faculty of Medicine, Gazi University, Ankara, Türkiye., Harmancı K; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Osmangazi University, Eskişehir, Türkiye., Hangül M; Department of Pediatric Pulmonology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye., Köse M; Department of Pediatric Pulmonology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye., Özdemir A; Department of Pediatric Pulmonology, Ministry of Health Mersin City Hospital, Mersin, Türkiye., Özcan G; Department of Pediatric Pulmonology, Faculty of Medicine, Ankara University, Ankara, Türkiye., Çobanoğlu N; Department of Pediatric Pulmonology, Faculty of Medicine, Ankara University, Ankara, Türkiye., Aydın ZGG; Department of Pediatric Infectious Diseases, Faculty of Medicine, Karadeniz Technical University, Trabzon, Türkiye., Keskin Ö; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Gaziantep University, Gaziantep, Türkiye., Yüksel H; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Celal Bayar University, Manisa, Türkiye., Özdoğan Ş; Department of Pediatric Pulmonology, Şişli Hamidiye Etfal Research and Training Hospital, İstanbul, Türkiye., Topal E; Department of Pediatric Allergy, Faculty of Medicine, İnönü University, Malatya, Türkiye., Çaltepe G; Department of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Türkiye., Can D; Department of Pediatric Pulmonology, Faculty of Medicine, Balıkesir University, Balıkesir, Türkiye., Korkmaz P; Department of Chest Diseases, Faculty of Medicine, Ege University, Izmir, Türkiye., Kılıç M; Department of Pediatric Pulmonology, Faculty of Medicine, Ege University, İzmir, Türkiye., Eyüboğlu TŞ; Department of Pediatric Pulmonology, Faculty of Medicine, Gazi University, Ankara, Türkiye., Pekcan S; Department of Pediatric Pulmonology, Meram Medicine Faculty, Necmettin Erbakan University, Konya, Türkiye., Çakır E; Department of Pediatric Pulmonology, Faculty of Medicine, İstinye University, İstanbul, Türkiye., Emiralioğlu N; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Özçelik U; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye., Doğru D; Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.

Source: The Turkish journal of pediatrics [Turk J Pediatr] 2026 Jun 30; Vol. 68 (3), pp. 439-449. Date of Electronic Publication: 2026 Jun 30.

Publication Type: Journal Article

Journal Info: Publisher: Hacettepe University, Institute of Child Health Country of Publication: Turkey NLM ID: 0417505 Publication Model: Electronic Cited Medium: Internet ISSN: 2791-6421 (Electronic) Linking ISSN: 00414301 NLM ISO Abbreviation: Turk J Pediatr Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/microbiology , Cystic Fibrosis*/complications , Cystic Fibrosis*/genetics , Pseudomonas aeruginosa*/isolation & purification , Pseudomonas Infections*/epidemiology , Pseudomonas Infections*/diagnosis, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Retrospective Studies ; Female ; Infant ; Male ; Registries ; Cross-Sectional Studies ; Infant, Newborn

Cystic fibrosis in a septuagenarian.

Authors: Johnson J; The Shrewsbury and Telford Hospital NHS Trust, Shropshire, UK jessie.johnson2@nhs.net., Ahmad N; The Shrewsbury and Telford Hospital NHS Trust, Shropshire, UK.

Source: BMJ case reports [BMJ Case Rep] 2026 Jun 29; Vol. 19 (6). Date of Electronic Publication: 2026 Jun 29.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE

MeSH Terms: Cystic Fibrosis*/diagnosis , Cystic Fibrosis*/genetics , Cystic Fibrosis*/complications , Bronchiectasis*/etiology , Bronchiectasis*/diagnostic imaging, Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Sweat/chemistry ; Humans ; Male