Cryo-Electron Microscopy-Based Epitope Mapping

Συγγραφείς: Drulyte, Ieva, Hurdiss, Daniel L

Πηγή: Methods in Molecular Biology ISBN: 9781071645901

Θεματικοί όροι: Epitopes, SDG 3 - Good Health and Well-being, Antigen-Antibody Complex/immunology, Cryoelectron Microscopy, Epitope Mapping/methods, Humans, Epitopes/immunology, Cryoelectron Microscopy/methods, Antigen-Antibody Complex, Epitope Mapping

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40593414

Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry

Συγγραφείς: Schulte, Douwe, Šiborová, Marta, Käll, Lukas, Snijder, Joost

Πηγή: eLife
eLife, Vol 14 (2025)

Θεματικοί όροι: Proteomics, QH301-705.5, Science, Cryoelectron Microscopy/methods, Tandem Mass Spectrometry/methods, Antibodies, proteomics, Immunology and Inflammation, Tandem Mass Spectrometry, Sequence Analysis, Protein, antibody, Humans, Biology (General), Chromatography, Liquid, epitope, Cryoelectron Microscopy, repertoire, cryoEM, Epitope Mapping/methods, Medicine, Proteomics/methods, Protein/methods, Antibodies/chemistry, Sequence Analysis, Epitope Mapping, Chromatography, Liquid

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40266252
https://doaj.org/article/dacc2b379ef0412fb4311005f9cc6368

Epitope Mapping with Sidewinder : An XL-MS and Structural Modeling Approach

Συγγραφείς: Ströbaek, Joel, Tang, Di, Gueto-Tettay, Carlos, Gomez Toledo, Alejandro, Olofsson, Berit, Hartman, Erik, Heusel, Moritz, Malmström, Johan, Malmström, Lars

Πηγή: International Journal of Molecular Sciences; 26(4), pp 1-17 (2025) ; ISSN: 1422-0067

Θεματικοί όροι: Bioinformatics (Computational Biology), Epitope Mapping/methods, Streptococcus pyogenes/immunology, Bacterial Proteins/chemistry, Molecular Docking Simulation, Antibodies, Monoclonal/chemistry, Mass Spectrometry/methods, Epitopes/immunology, Streptolysins/chemistry, Bacterial/immunology

Relation: http://dx.doi.org/10.3390/ijms26041488; pmid:40003954; scopus:85218901966

Διαθεσιμότητα: https://lup.lub.lu.se/record/18960a88-0ea4-4ce7-a6c1-34132a89496d
https://doi.org/10.3390/ijms26041488

The XcpV/GspI Pseudopilin Has a Central Role in the Assembly of a Quaternary Complex within the T2SS Pseudopilus

Συγγραφείς: Douzi, Badreddine, Alphonse, Sébastien, Darbon, Herve, Filloux, Alain, Cambillau, Christian, Bernard, Cedric, Tegoni, Mariella, Voulhoux, Romé

Συνεισφορές: ProdInra, Migration

Πηγή: Journal of Biological Chemistry. 284:34580-34589

Θεματικοί όροι: 0301 basic medicine, Protein Structure, 0303 health sciences, Protein Isoforms/*chemistry/genetics/*metabolism, Protein Conformation, [SDV]Life Sciences [q-bio], Pseudomonas aeruginosa/cytology/genetics/*metabolism, Surface Plasmon Resonance, Protein Structure, Tertiary, [SDV] Life Sciences [q-bio], 03 medical and health sciences, Bacterial Proteins, Multiprotein Complexes/metabolism, Multiprotein Complexes, Pseudomonas aeruginosa, Epitope Mapping/methods, Protein Isoforms, Protein Multimerization, Tertiary, Bacterial Proteins/*chemistry/genetics/*metabolism, Epitope Mapping

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: http://www.jbc.org/content/284/50/34580.full.pdf
https://pubmed.ncbi.nlm.nih.gov/19828448
https://hal.inrae.fr/hal-02824819v1
https://hal.inrae.fr/hal-02824819v1/document
https://hal.inrae.fr/hal-02666049v1
https://doi.org/10.1074/jbc.m109.042366

Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A

Συγγραφείς: Kristina M. Geiger, Daniel Guignard, Che Yang, Jean-Pierre Bikorimana, Bruno E. Correia, Sophie Houard, Catherine Mkindi, Claudia A. Daubenberger, François Spertini, Giampietro Corradin, Régine Audran

Πηγή: Front Immunol
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology.-2020
Frontiers in immunology, vol. 11, pp. 412

Θεματικοί όροι: Adult, 0301 basic medicine, Adjuvants, Immunologic, Antibodies, Protozoan/metabolism, Antibody Affinity, Antigens, Protozoan/genetics, Antigens, Protozoan/immunology, Epitope Mapping/methods, Epitopes, B-Lymphocyte/genetics, Epitopes, B-Lymphocyte/immunology, Epitopes, T-Lymphocyte/genetics, Epitopes, T-Lymphocyte/immunology, Humans, Life Cycle Stages, Lymphocyte Activation, Malaria Vaccines/immunology, Malaria, Falciparum/immunology, Peptides/genetics, Peptides/immunology, Plasmodium falciparum, Protozoan Proteins/genetics, Protozoan Proteins/immunology, Switzerland, Tanzania, Vaccination, P27A, adjuvant, clinical trial, immune response, malaria, populations, vaccine, Immunology, Protozoan Proteins, Antibodies, Protozoan, Epitopes, T-Lymphocyte, Antigens, Protozoan, 03 medical and health sciences, Malaria Vaccines, Malaria, Falciparum, RC581-607, 3. Good health, Epitopes, B-Lymphocyte, Immunologic diseases. Allergy, Peptides, Epitope Mapping

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://www.frontiersin.org/articles/10.3389/fimmu.2020.00412/pdf
https://pubmed.ncbi.nlm.nih.gov/32210975
https://doaj.org/article/8aa2e3adbc2a4cbca7e1e48344279cbc
https://sonar.ch/global/documents/172983
https://serval.unil.ch/resource/serval:BIB_941F355259B5.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_941F355259B5
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_941F355259B52

Automatic Generation of Validated Specific Epitope Sets

Συγγραφείς: Sebastian Carrasco Pro, John Sidney, Sinu Paul, Cecilia S. Lindestam Arlehamn, Daniela Weiskopf, Bjoern Peters, Alessandro Sette

Πηγή: J Immunol Res
Journal of Immunology Research, Vol 2015 (2015)

Θεματικοί όροι: 0301 basic medicine, Herpesvirus 4, Human, Databases, Factual, Epitopes, T-Lymphocyte/metabolism, T-Lymphocytes, Epitopes, T-Lymphocyte, Lymphocyte Activation, Prediction of Peptide-MHC Binding Affinity, Computational biology, Context (archaeology), 0302 clinical medicine, Precision Medicine, Mycobacteriaceae, Cells, Cultured, Immunology and Microbiology, Dengue Virus/immunology, Life Sciences, 3. Good health, Antigen, Mycobacteriaceae/immunology, Immune Responses, Epitope, Immunotherapy, Research Article, Herpesvirus 4, Human/immunology, T-Cell Epitopes, Immunobiology of Dendritic Cells, Immunology, Immunologic Tests, Viral Proteins, 03 medical and health sciences, Biochemistry, Genetics and Molecular Biology, Virology, Humans, Molecular Biology, Biology, Electronic Data Processing, FOS: Clinical medicine, T cell, Paleontology, T-Lymphocytes/immunology, RC581-607, Dengue Virus, Computer science, Epitope Mapping/methods, Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome, Viral Proteins/immunology, Epitope Prediction, Immunologic diseases. Allergy, B-Cell Epitopes, Epitope Mapping, Software

Περιγραφή αρχείου: text/xhtml

Σύνδεσμος πρόσβασης: http://downloads.hindawi.com/journals/jir/2015/763461.pdf
https://pubmed.ncbi.nlm.nih.gov/26568965
https://doaj.org/article/f64e530d503d4d40bbf6209b232b1c7c
https://hdl.handle.net/20.500.12866/5352
https://doi.org/10.1155/2015/763461

Molecular and Therapeutic Characterization of Anti-ectodysplasin A Receptor (EDAR) Agonist Monoclonal Antibodies

Συγγραφείς: Kowalczyk Christine, Dunkel Nathalie, Willen Laure, Casal Margret L, Mauldin Elizabeth A, Gaide Olivier, Tardivel Aubry, Badic Giovanna, Etter Anne-Lise, Favre Manuel, Jefferson Douglas M, Headon Denis J, Demotz Stéphane, Schneider Pascal

Πηγή: The Journal of biological chemistry.-2011
Journal of Biological Chemistry, vol. 286, no. 35, pp. 30769-30779
Kowalczyk, C, Dunkel, N, Willen, L, Casal, M L, Mauldin, E A, Gaide, O, Tardivel, A, Badic, G, Etter, A L, Favre, M, Jefferson, D M, Headon, D J, Demotz, S & Schneider, P 2011, 'Molecular and therapeutic characterization of anti-Ectodysplasin A receptor (EDAR) agonist monoclonal antibodies', Journal of Biological Chemistry, vol. 286, no. 35, pp. 30769-30779. https://doi.org/10.1074/jbc.M111.267997
J Biol Chem
The Journal of biological chemistry

Θεματικοί όροι: Animals, Antibodies, Monoclonal/chemistry, Cell Separation, Chickens, Dogs, Enzyme-Linked Immunosorbent Assay/methods, Epitope Mapping/methods, Flow Cytometry, Humans, Ligands, Mice, Molecular Sequence Data, Mutation, Phenotype, Plasmids/metabolism, Rats, Receptors, Ectodysplasin/chemistry, Receptors, Ectodysplasin/immunology, Surface Plasmon Resonance, Tooth/embryology, Tumor Necrosis Factor-alpha/metabolism, 0301 basic medicine, 0303 health sciences, Receptors, Ectodysplasin, Tumor Necrosis Factor-alpha, Antibodies, Monoclonal, Enzyme-Linked Immunosorbent Assay, 3. Good health, 03 medical and health sciences, Tooth, Epitope Mapping, Plasmids

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: http://www.jbc.org/content/286/35/30769.full.pdf
https://pubmed.ncbi.nlm.nih.gov/21730053
https://sonar.ch/global/documents/106025
https://serval.unil.ch/notice/serval:BIB_9E190030D736
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9E190030D7360
https://serval.unil.ch/resource/serval:BIB_9E190030D736.P001/REF.pdf

Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome.

Συγγραφείς: MacDonald, Brian A, Author, Sund, Malin, Author, Grant, Marianne A, Author, Pfaff, Kathleen L, Author, Holthaus, Kathryn, Author, Zon, Leonard I, Author, Kalluri, Raghu, Author

Συνεισφορές: MacDonald, Brian A, Author, Sund, Malin, Author, Grant, Marianne A, Author, Pfaff, Kathleen L, Author, Holthaus, Kathryn, Author, Zon, Leonard I, Author, Kalluri, Raghu, Author

Πηγή: Blood. 107(5):1908-1915

Θεματικοί όροι: Animals, Anti-Glomerular Basement Membrane Disease/genetics/*immunology, Antibody Specificity/immunology, Autoantibodies/*immunology, Autoantigens/genetics/*immunology, Collagen Type IV/genetics/*immunology, Epitope Mapping/methods, Epitopes/genetics/*immunology, Evolution, Molecular, Humans, Mice, Sequence Homology, Amino Acid, Species Specificity, Structural Homology, Protein, Zebrafish/genetics/immunology

Περιγραφή αρχείου: print

Σύνδεσμος πρόσβασης: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-6057

Evolutionary and immunological implications of contemporary HIV-1 variation

Συγγραφείς: Korber, Bette T, Gaschen, Brian, Yusim, Karina, Thakallapally, R, Kesmir, Can, Detours, Vincent

Πηγή: British Medical Bulletin, 58

Θεματικοί όροι: T-Lymphocytes, Cytotoxic -- drug effects, Evolution, T-Lymphocytes, Genetic Variation -- immunology, HIV-1 -- pathogenicity, Cross Reactions, Global Health, Evolution, Molecular, Epitope Mapping -- methods, Epitopes, 03 medical and health sciences, 0302 clinical medicine, HIV-1 -- genetics, HIV-1 -- immunology, Animals, Humans, Mutation -- genetics, Antigenic Variation -- genetics, Cross Reactions -- immunology, Genetic Variation -- genetics, Epitopes -- genetics, Phylogeny, Haemophilus Vaccines, AIDS Vaccines, Molecular, Genetic Variation, Sciences bio-médicales et agricoles, Antigenic Variation, 3. Good health, Cytotoxic -- drug effects, Influenza A virus -- genetics, AIDS Vaccines -- immunology, Influenza A virus, Drug Design, World Health, Mutation, HIV-1, Haemophilus Vaccines -- pharmacology, Epitope Mapping, T-Lymphocytes, Cytotoxic

Περιγραφή αρχείου: 2 full-text file(s): application/pdf; application/pdf

Σύνδεσμος πρόσβασης: https://academic.oup.com/bmb/article-pdf/58/1/19/25151348/19.pdf
https://pubmed.ncbi.nlm.nih.gov/11714622
https://dipot.ulb.ac.be/dspace/bitstream/2013/50687/6/2e05663e-0628-4c47-980c-b45c1d051a3e.txt
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50687
https://dipot.ulb.ac.be/dspace/bitstream/2013/50687/3/doi_25749.pdf

Mapping thyroid peroxidase epitopes using recombinant protein fragments

Συγγραφείς: TONACCHERA, MASSIMO, CETANI F, COSTAGLIOLA S, ALCALDE L, UIBO R, VASSART G, LUDGATE M.

Πηγή: European journal of endocrinology, 132 (1

Θεματικοί όροι: Adult, Male, 0301 basic medicine, Adolescent, Molecular Probes -- genetics, Blotting, Western, Molecular Sequence Data, Gastric -- immunology, Parietal Cells, Gastric -- immunology, Peptide Fragments -- immunology, Iodide Peroxidase, Epitope Mapping -- methods, Epitopes, 03 medical and health sciences, 0302 clinical medicine, Parietal Cells, Gastric, Thyroid Diseases -- immunology, Reference Values, 80 and over, Humans, Aged, Aged, 80 and over, Base Sequence, Blotting, Parietal Cells, Iodide Peroxidase -- chemistry, Sciences bio-médicales et agricoles, Middle Aged, Thyroid Diseases, Peptide Fragments, Recombinant Proteins, 3. Good health, Molecular Probes, Female, Iodide Peroxidase -- immunology, Western, Epitope Mapping

Περιγραφή αρχείου: No full-text files

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/7531575
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/56293
https://hdl.handle.net/11568/27923

Epitope mapping via in vitro deep mutational scanning methods and its applications

Συγγραφείς: Keen, Meredith M., Keith, Alasdair D., Ortlund, Eric A. ^∗

Πηγή: In Journal of Biological Chemistry

Identification of the epitope in human poliovirus type 1 Sabin strain recognized by the monoclonal antibody 1G10 using mimotope strategy

Συγγραφείς: Bai, Han ^a, Liu, Shaohua ^a, Shi, Shenghe ^b, Lu, Weiwei ^a, Yang, Yongjuan ^a, Zhu, Yunkai ^a, Zhang, Zhongyang ^a, Guo, Huijie ^a, Li, Xiuling ^{a, *}

Πηγή: In Journal of Virological Methods February 2020 276

Sorting and pooling strategy: a novel tool to map a virus proteome for CD8 T-cell epitopes

Συγγραφείς: Bernhard Ay, Mathias Streitz, Prisca Boisguerin, Andreas Schlosser, Carsten C. Mahrenholz, Sebastian D. Schuck, Florian Kern, Rudolf Volkmer

Θεματικοί όροι: Amino Acid Sequence, Biopolymers/chemistry, CD8-Positive T-Lymphocytes/*immunology, Cytomegalovirus/*genetics/*immunology, Epitope Mapping/*methods, Epitopes/*chemistry, Flow Cytometry, Genome, Viral, Humans, Oligopeptides/chemistry, Peptide Mapping, Proteome, Proteomics/*methods

Relation: 10779/uos.23389010.v1

Διαθεσιμότητα: https://figshare.com/articles/journal_contribution/Sorting_and_pooling_strategy_a_novel_tool_to_map_a_virus_proteome_for_CD8_T-cell_epitopes/23389010

An Overview of Epitopes and Methods for Antibody Epitope Mapping.

Συγγραφείς: Nilvebrant J; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden., Berndt Thalén N; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden., Rockberg J; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden. johanr@biotech.kth.se., Malm M; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden. magdalena.malm@biotech.kth.se.

Πηγή: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2937, pp. 1-11.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Epitopes*/immunology , Epitopes*/chemistry , Epitopes*/genetics , Antibodies*/immunology , Antibodies*/chemistry, Computational Biology/methods ; Antigens/immunology ; Antigens/chemistry ; Humans ; Animals

An Overview of Epitopes and Methods for Antibody Epitope Mapping

Συγγραφείς: Nilvebrant, Johan, Thalén, Niklas Berndt, Rockberg, Johan, Malm, Magdalena

Όροι ευρετηρίου: Antibody, Antigen, Epitope, Epitope mapping, Peptide, Prediction, Structural biology, Medical Biotechnology (Focus on Cell Biology, (incl. Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy), Medicinsk bioteknologi (Inriktn. mot cellbiologi (inkl. stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci), Chapter in book, info:eu-repo/semantics/bookPart, text

Σύνδεσμος: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-377724
Methods in Molecular Biology, p. 1-11

T-cell epitope mapping

Συγγραφείς: Malherbe, Laurent ^**

Πηγή: In Annals of Allergy, Asthma & Immunology 2009 103(1):76-79

HLA class I-naturally presented synovial tissue peptides are recognized by CD8+ T lymphocytes from rheumatoid arthritis patients.

Συγγραφείς: Catalán, Diego, Schneider, Daniela, Pesce, Bárbara, Jaime, Miqueas, Toro, Lucero, Varela-Villarroel, Constanza, Montano-Bruno, Darly, Soto, Lilian, Bozán, Francisca, Cuéllar-Gutiérrez, María Carolina, Neira, Óscar, Arroyo, Consuelo, Rivera, Guido, Larrondo, Milton, Hinzpeter, Jaime, Carrascal, Montserrat, Aguillón, Juan C., Maggi, Jaxaira

Πηγή: Frontiers in Immunology; 2026, p1-17, 17p

Θεματικοί όροι: Cytotoxic T cells, Autoantigens, Mass spectrometry, Major histocompatibility complex, Synovial membranes, Rheumatoid arthritis, Dendritic cells

Artificial intelligence advancements in monoclonal antibody development technology.

Συγγραφείς: Ammar, Manar, Samsonov, Mikhail, Gurylina, Evgeniya, Bayzigitov, Daniel

Πηγή: Frontiers in Immunology; 2026, p1-22, 22p

Θεματικοί όροι: Artificial intelligence, Monoclonal antibodies, Immunotechnology, Protein models, Bioinformatics software, Antibody therapy

Engineering molecularly imprinted polymers for receptor-specific cancer therapeutics.

Συγγραφείς: Tiwari, Shreya, Hutchinson, Charles L., Singla, Pankaj, Rintoul, Robert C., Witney, Timothy H., Turner, Nicholas W., Peeters, Marloes

Πηγή: Nanoscale; 6/4/2026, Vol. 18 Issue 21, p11064-11091, 28p

Vaccines for the control of cattle ticks in Uganda

Συγγραφείς: Fuente, José de la, Contreras, Marinela, Ministerio de Economía, Industria y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Consejo Superior de Investigaciones Científicas (España), National Agricultural Research Foundation, Junta de Comunidades de Castilla-La Mancha, Kasaija, Paul D.

Όροι ευρετηρίου: tesis doctoral

Σύνδεσμος: http://hdl.handle.net/10261/341103
Sí
info:eu-repo/grantAgreement/MINECO//BFU2016-79892-P
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-116761GB-I00/ES/IDENTIFICACION Y CARACTERIZACION DE BIOMOLECULAS EN LA SALIVA DE GARRAPATAS Y MECANISMOS ASOCIADOS CON LA RESPUESTA INMUNE FRENTE A ALPHA-GAL