Generation and epitope mapping of two distinct neutralizing mAb subsets targeting BVDV E2: a pan-pestivirus cross-reactive linear epitope and a BVDV-specific conformational epitope.

Συγγραφείς: Bao F; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China., Mi S; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, 130122, China., Liu Z; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China., Zhang S; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China., Wu M; Chongqing Academy of Animal Sciences, Chongqing, 402460, China., Zhang Y; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China., Tu C; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China. changchun_tu@hotmail.com.; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, 130122, China. changchun_tu@hotmail.com.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, China. changchun_tu@hotmail.com., Gong W; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China. gong@jlu.edu.cn.

Πηγή: Veterinary research [Vet Res] 2026 Oct 07; Vol. 57 (1). Date of Electronic Publication: 2026 Oct 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: BioMed Central Country of Publication: England NLM ID: 9309551 Publication Model: Electronic Cited Medium: Internet ISSN: 1297-9716 (Electronic) Linking ISSN: 09284249 NLM ISO Abbreviation: Vet Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/veterinary , Antibodies, Monoclonal*/immunology , Diarrhea Viruses, Bovine Viral*/immunology , Epitopes*/immunology , Antibodies, Neutralizing*/immunology , Viral Envelope Proteins*/immunology , Antibodies, Viral*/immunology, Animals ; Cattle ; Cross Reactions

NIE Antigen Mapping for Serological Diagnostic of Strongyloidiasis.

Συγγραφείς: Cambra-Pellejà M; ISGlobal, 08036Barcelona, Spain.; GraphenicaLab SL, 08018Barcelona, Spain.; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08007Barcelona, Spain., Aguilar R; ISGlobal, 08036Barcelona, Spain., Vidal M; ISGlobal, 08036Barcelona, Spain., Pejenaute A; Center for Cooperative Research in Biosciences CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Science and Technology Park, Building 800, 48160Derio, Spain.; Tekniker, Basque Research and Technology Alliance (BRTA), C/Iñaki Goenaga 5, 20600Eibar, Spain., Jiménez A; ISGlobal, 08036Barcelona, Spain., Fleitas P; ISGlobal, 08036Barcelona, Spain., Simao CD; GraphenicaLab SL, 08018Barcelona, Spain., Baptista-Pires L; I3N, Physics Department, University of Aveiro, Aveiro3810-193, Portugal., Camprubí-Ferrer D; ISGlobal, 08036Barcelona, Spain.; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08007Barcelona, Spain.; International Health Department Hospital Clinic de Barcelona, 08036Barcelona, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain., Muñoz J; ISGlobal, 08036Barcelona, Spain.; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08007Barcelona, Spain.; International Health Department Hospital Clinic de Barcelona, 08036Barcelona, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain., Ortega-Quintanilla G; Center for Cooperative Research in Biosciences CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Science and Technology Park, Building 800, 48160Derio, Spain.; Ikerbasque, Basque Foundation for Science, Plaza Euskadi 5, 48009Bilbao, Spain., Dobaño C; ISGlobal, 08036Barcelona, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain., Parolo C; ISGlobal, 08036Barcelona, Spain.; INTERFIBIO Research Group, Departament d'Enginyeria Química, Universitat Rovira iVirgili, 43007Tarragona, Spain., Gandasegui J; ISGlobal, 08036Barcelona, Spain.

Πηγή: ACS infectious diseases [ACS Infect Dis] 2026 Sep 11; Vol. 12 (9), pp. 3104-3113.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Strongyloidiasis*/diagnosis , Strongyloidiasis*/immunology , Epitope Mapping*/methods , Antigens, Helminth*/immunology , Antigens, Helminth*/chemistry , Antigens, Helminth*/genetics , Strongyloides stercoralis*/immunology, Serologic Tests/methods ; Antibodies, Helminth/blood ; Immunoglobulin G/blood ; Animals ; Humans ; Amino Acid Sequence

MAXTIA: A high-throughput platform for rapid functional epitope mapping by kinetic screening of mutant libraries.

Συγγραφείς: Kim K; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan., Matsunaga R; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.; Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan., Yokoo T; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan., Nakakido M; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.; Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan., Tsumoto K; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.; Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan.; The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

Πηγή: Protein science : a publication of the Protein Society [Protein Sci] 2026 Sep; Vol. 35 (9), pp. e70769.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Epitopes*/chemistry , Epitopes*/genetics , Epitopes*/immunology , High-Throughput Screening Assays*/methods , C-Reactive Protein*/chemistry , C-Reactive Protein*/genetics , C-Reactive Protein*/immunology, Kinetics ; Surface Plasmon Resonance ; Models, Molecular ; Mutation

Mass spectrometry-based mapping of conformational epitopes on SARS-CoV-2 antigens targeted by monoclonal antibodies.

Συγγραφείς: Pianpaktr P; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Pharmaceutical Sciences and Technology (PST) Graduate Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: p.pianpaktr@gmail.com., Ramanandana P; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Pharmaceutical Sciences and Technology (PST) Graduate Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Huachiew Chalermprakiet University, Bang Phli, Samut Prakan, 10540, Thailand. Electronic address: waew2.pr@gmail.com., Nanthawong S; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: saharat.nanthawongb@gmail.com., Wongtangprasert T; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; The Excellence Chulalongkorn Comprehensive Cancer Center, King Chulalongkorn Memorial Hospital, Pathumwan, Bangkok, 10330, Thailand. Electronic address: cassavara@gmail.com., Saelao P; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: p.saelao11@gmail.com., Muanwien P; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: phijitra.jame7@gmail.com., Boonkrai C; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: ctkorn@gmail.com., Cicek H; SARomics Biostructures AB, Medicon Village, Lund, 223 81, Sweden. Electronic address: hasan.cicek@saromics.com., Focht D; SARomics Biostructures AB, Medicon Village, Lund, 223 81, Sweden. Electronic address: dorota.focht@saromics.com., Kimbung R; SARomics Biostructures AB, Medicon Village, Lund, 223 81, Sweden. Electronic address: Raymond.kimbung@saromics.com., Welin M; SARomics Biostructures AB, Medicon Village, Lund, 223 81, Sweden. Electronic address: martin.welin@saromics.com., Stahl VL; Department of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, United States. Electronic address: vstahl@umass.edu., Graban EM; QuarryBio Inc., Bloomington, IN, 47404, United States. Electronic address: eric.graban@reclaim-rx.com., Vachet RW; Department of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, United States. Electronic address: rwvachet@chem.umass.edu., Pisitkun T; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Division of Research Affairs, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: trairak@gmail.com., Limpikirati PK; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Pharmaceutical Sciences and Technology (PST) Graduate Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Center of Excellence in Systems Biology (CUSB), Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. Electronic address: patanachai.l@pharm.chula.ac.th.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2026 Aug; Vol. 372, pp. 153102. Date of Electronic Publication: 2026 Jun 21.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Antibodies, Monoclonal*/immunology , Antibodies, Monoclonal*/chemistry , Epitope Mapping*/methods , Spike Glycoprotein, Coronavirus*/immunology , Spike Glycoprotein, Coronavirus*/chemistry , Epitopes*/immunology , Epitopes*/chemistry , SARS-CoV-2*/immunology , SARS-CoV-2*/chemistry , Antigens, Viral*/immunology , Antigens, Viral*/chemistry , Antibodies, Viral*/immunology, Mass Spectrometry/methods ; Humans ; Tandem Mass Spectrometry ; Models, Molecular

Patient-Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next-Generation Allergen Immunotherapy.

Συγγραφείς: Šošić L; Department of Dermatology, University of Zurich, Schlieren, Switzerland., Paolucci M; Department of Dermatology, University of Zurich, Schlieren, Switzerland., Streuli A; Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.; Laboratory for Pharmaceutical Analytics, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland., Melillo DA; Department of Dermatology, University of Zurich, Schlieren, Switzerland., Jiang T; Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Campana R; Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Lang CCV; Department of Dermatology, University of Zurich, Schlieren, Switzerland.; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Kündig TM; Department of Dermatology, University of Zurich, Schlieren, Switzerland.; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Steuer C; Laboratory for Pharmaceutical Analytics, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland., Eyer K; Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Johansen P; Department of Dermatology, University of Zurich, Schlieren, Switzerland.; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

Πηγή: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2026 Aug; Vol. 56 (8), pp. 881-892. Date of Electronic Publication: 2026 Mar 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8906443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2222 (Electronic) Linking ISSN: 09547894 NLM ISO Abbreviation: Clin Exp Allergy Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Immunoglobulin G*/immunology , Immunoglobulin G*/blood , Desensitization, Immunologic*/methods , Antigens, Plant*/immunology , Antigens, Plant*/chemistry , Allergens*/immunology , Peptides*/immunology , Rhinitis, Allergic, Seasonal*/immunology , Rhinitis, Allergic, Seasonal*/therapy , Epitope Mapping*, Basophils/immunology ; Immunoglobulin E/immunology ; Immunoglobulin E/blood ; Epitopes/immunology ; Humans ; Female ; Adult ; Male

Linear antibody epitope prediction using AlphaFold2.

Συγγραφείς: DeRoo J; School of Biomedical Engineering, Colorado State University, Fort Collins, United States., Terry JS; Department of Microbiology, Immunology, & Pathology, Colorado State University, Fort Collins, United States., Zhao N; Department of Biochemistry and Molecular Genetics, University of Colorado-Anschutz Medical Campus, Aurora, United States., Stasevich TJ; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, United States., Snow C; School of Biomedical Engineering, Colorado State University, Fort Collins, United States.; Department of Chemical & Biological Engineering, Colorado State University, Fort Collins, United States., Geiss BJ; School of Biomedical Engineering, Colorado State University, Fort Collins, United States.; Department of Microbiology, Immunology, & Pathology, Colorado State University, Fort Collins, United States.

Πηγή: ELife [Elife] 2026 Sep 18; Vol. 13. Date of Electronic Publication: 2026 Sep 18.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitopes*/immunology , Epitopes*/chemistry , Epitope Mapping*/methods , Computational Biology*/methods, Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/chemistry ; Prediction Algorithms ; Algorithms ; Humans

Mimotope-Guided Molecular Dynamics Enables Precise Functional Epitope Mapping.

Συγγραφείς: Sha Z; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China., Hu Z; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China., Du W; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China., Marti J; Department of Physics, Polytechnic University of Catalonia-Barcelona Tech, B4-B5 Northern Campus, Barcelona, Catalonia08034, Spain., Sundell GN; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China.; TongRen Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning District, Shanghai200000, China., Guo SJ; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China., Zhao X; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China., Tao SC; Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang, Shanghai200240, China.

Πηγή: Journal of chemical information and modeling [J Chem Inf Model] 2026 Sep 14; Vol. 66 (17), pp. 11259-11274.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Epitopes*/chemistry , Epitopes*/immunology , Molecular Dynamics Simulation*, Protein Conformation

epiTOol: a browser-based HLA epitope (mis)matching application for small to large cohorts.

Συγγραφείς: Lehmann C; Institute for Transfusion Medicine, HLA Laboratory, University Hospital Hamburg-Eppendorf, Hamburg, Germany.; Institute for Clinical Immunology, University of Leipzig, Leipzig, Germany., Lachmann N; Institute for Transfusion Medicine, H & I Laboratory, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany., Doxiadis I; Institute for Transfusion Medicine, HLA Laboratory, University Hospital Hamburg-Eppendorf, Hamburg, Germany.; Institute for Clinical Immunology, University of Leipzig, Leipzig, Germany., Loeffler-Wirth H; Interdisciplinary Centre for Bioinformatics (IZBI), Leipzig University, Leipzig, Germany.; Bioinformatics Group, Department of Computer Science, University of, Leipzig, Leipzig, Germany.; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.

Πηγή: Frontiers in immunology [Front Immunol] 2026 Sep 07; Vol. 17, pp. 1916548. Date of Electronic Publication: 2026 Sep 07 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): HLA Antigens*/immunology , HLA Antigens*/genetics , Histocompatibility Testing*/methods , Epitopes*/immunology , Epitopes*/genetics , Epitope Mapping*/methods , Software* , Web Browser*, Humans

Phage ImmunoPrecipitation sequencing (PhIP-Seq) in autoimmunity research: From high-resolution epitope mapping to multi-omics integration.

Συγγραφείς: Yu R; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China; Eight-year Medical Doctor Program, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Lu R; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China; Department of Laboratory Medicine, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen, China., Xue C; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China., Bai Y; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China., Li M; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China., Hu C; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China. Electronic address: huchaojun818@qq.com.

Πηγή: Autoimmunity reviews [Autoimmun Rev] 2026 Aug; Vol. 25 (8), pp. 104094. Date of Electronic Publication: 2026 May 22.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128967 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-0183 (Electronic) Linking ISSN: 15689972 NLM ISO Abbreviation: Autoimmun Rev Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Autoimmune Diseases*/immunology , Autoimmune Diseases*/diagnosis , Autoimmunity*/genetics , High-Throughput Nucleotide Sequencing*/methods , Immunoprecipitation*/methods, Autoantibodies/immunology ; Autoantigens/immunology ; Autoantigens/genetics ; Epitopes/immunology ; Humans ; Multiomics ; Animals ; Peptide Library ; Immunoinformatics

Epitope Mapping of Anti-mouse ACKR4 Monoclonal Antibodies Developed by N-Terminal Peptide Immunization.

Συγγραφείς: Hirose M; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Tanaka T; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Yanaka M; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Nakamura T; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Kaneko MK; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Suzuki H; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Kato Y; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Πηγή: Monoclonal antibodies in immunodiagnosis and immunotherapy [Monoclon Antib Immunodiagn Immunother] 2026 Jul-Aug; Vol. 45 (4), pp. 69-75. Date of Electronic Publication: 2026 Jun 16.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101590955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2167-9436 (Electronic) Linking ISSN: 21679436 NLM ISO Abbreviation: Monoclon Antib Immunodiagn Immunother Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Antibodies, Monoclonal*/immunology , Epitopes*/immunology , Peptides*/immunology , Receptors, CXCR*/immunology , Receptors, CXCR*/genetics, Animals ; Mice ; Immunization ; Flow Cytometry ; Humans

Epitope Mapping of Anti-Mouse C-C Motif Chemokine Receptor 1 Monoclonal Antibodies Developed by the Cell-Based Immunization and Screening Method.

Συγγραφείς: Okada A; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Suzuki H; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Kaneko MK; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Kato Y; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Πηγή: Monoclonal antibodies in immunodiagnosis and immunotherapy [Monoclon Antib Immunodiagn Immunother] 2026 Jul-Aug; Vol. 45 (4), pp. 58-68. Date of Electronic Publication: 2026 Jun 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101590955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2167-9436 (Electronic) Linking ISSN: 21679436 NLM ISO Abbreviation: Monoclon Antib Immunodiagn Immunother Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Antibodies, Monoclonal*/immunology , Receptors, CCR1*/immunology , Receptors, CCR1*/genetics , Epitopes*/immunology , Epitopes*/chemistry, Animals ; Mice ; Flow Cytometry ; Immunization ; Humans

IgM and IgG Epitope Mapping of the Porin Outer Membrane Protein-2a from Brucella abortus: Potential Biomarkers for Detecting Exposure to Brucellosis.

Συγγραφείς: Noguera AF; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, Brazil.; Technological Center of the Marine Corps (CTecFN), Brazilian Navy, Rio de Janeiro 21010-076, Brazil., Lechuga GC; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, Brazil., Napoleão-Pêgo P; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, Brazil.; Technological Center of the Marine Corps (CTecFN), Brazilian Navy, Rio de Janeiro 21010-076, Brazil., Carvalho JPRS; Program of Post-Graduation on Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, Brazil., Gomes LR; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, Brazil., Carneiro da Silva A; Technological Center of the Marine Corps (CTecFN), Brazilian Navy, Rio de Janeiro 21010-076, Brazil., Melo Monnerat M; Technological Center of the Marine Corps (CTecFN), Brazilian Navy, Rio de Janeiro 21010-076, Brazil., da Silva FR; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, Brazil., De-Simone SG; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, Brazil.; Technological Center of the Marine Corps (CTecFN), Brazilian Navy, Rio de Janeiro 21010-076, Brazil.; Program of Post-Graduation on Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, Brazil.; Program of Post-Graduation on Parasitic Biology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2026 Jun 13; Vol. 27 (12). Date of Electronic Publication: 2026 Jun 13.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Immunoglobulin M*/immunology , Immunoglobulin G*/immunology , Epitope Mapping*/methods , Brucella abortus*/immunology , Brucellosis*/diagnosis , Brucellosis*/immunology , Brucellosis*/microbiology , Brucellosis*/blood , Porins*/immunology , Bacterial Outer Membrane Proteins*/immunology, Biomarkers/blood ; Antibodies, Bacterial/immunology ; Epitopes, B-Lymphocyte/immunology ; Antigens, Bacterial/immunology ; Humans ; Enzyme-Linked Immunosorbent Assay ; Animals ; Cross Reactions

Development and epitope mapping of monoclonal antibodies against group a porcine rotavirus VP6 protein.

Συγγραφείς: Hu Y; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Wu H; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Xiao Y; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Gao X; China Animal Health and Epidemiology Center, Qingdao, 266032, PR China., Sun R; Qingdao Lijian Bio-tech Co., Ltd., Qingdao, Shandong, 266041, PR China., Xin W; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Chen Z; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Wu X; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Ding Z; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Song D; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China., Wu H; Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China; Jiangxi Provincial Key Laboratory for Animal Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, PR China. Electronic address: huanswu@jxau.edu.cn.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jun; Vol. 366, pp. 152548. Date of Electronic Publication: 2026 May 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Antibodies, Monoclonal*/immunology , Capsid Proteins*/immunology , Capsid Proteins*/chemistry , Capsid Proteins*/genetics , Antigens, Viral*/immunology , Antigens, Viral*/chemistry , Antigens, Viral*/genetics , Rotavirus*/immunology , Rotavirus*/genetics , Epitope Mapping*/methods, Epitopes, B-Lymphocyte/immunology ; Epitopes, B-Lymphocyte/chemistry ; Antibodies, Viral/immunology ; Recombinant Proteins/immunology ; Animals ; Swine ; Amino Acid Sequence ; Molecular Docking Simulation

Integrated workflow for production and in vitro characterization of equine anti-SARS-CoV-2 hyperimmune serum with epitope mapping.

Συγγραφείς: de Santana Evangelista K; Industrial Directorate, Ezequiel Dias Foundation (Funed), Belo Horizonte, MG, 30510-010, Brazil., de Castro Barbosa E; Research and Development Directorate, Funed, Belo Horizonte, MG 30510-010, Brazil., de Souza Andrade A; Research and Development Directorate, Funed, Belo Horizonte, MG 30510-010, Brazil., Ardisson L; Industrial Directorate, Ezequiel Dias Foundation (Funed), Belo Horizonte, MG, 30510-010, Brazil., Martins AA; Industrial Directorate, Ezequiel Dias Foundation (Funed), Belo Horizonte, MG, 30510-010, Brazil., Boasquivis PF; Industrial Directorate, Ezequiel Dias Foundation (Funed), Belo Horizonte, MG, 30510-010, Brazil., Duarte MM; Octávio Magalhães Institute Directorate, Funed, Belo Horizonte, MG, 30510-010, Brazil., de Oliveira Ribeiro B; Research and Development Directorate, Funed, Belo Horizonte, MG 30510-010, Brazil; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil., de Souza Filho JA; Research and Development Directorate, Funed, Belo Horizonte, MG 30510-010, Brazil., Borges MH; Research and Development Directorate, Funed, Belo Horizonte, MG 30510-010, Brazil., de Oliveira Souza G; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil., Olórtegui CC; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil., Luzia AB; Industrial Directorate, Ezequiel Dias Foundation (Funed), Belo Horizonte, MG, 30510-010, Brazil., Caldas S; Research and Development Directorate, Funed, Belo Horizonte, MG 30510-010, Brazil. Electronic address: sergio.caldas@funed.mg.gov.br.

Πηγή: Journal of immunological methods [J Immunol Methods] 2026 May; Vol. 548, pp. 114059. Date of Electronic Publication: 2026 May 09.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1305440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7905 (Electronic) Linking ISSN: 00221759 NLM ISO Abbreviation: J Immunol Methods Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Epitope Mapping*/methods , Antibodies, Viral*/immunology , Antibodies, Viral*/blood , SARS-CoV-2*/immunology , Antibodies, Neutralizing*/immunology, COVID-19/immunology ; Spike Glycoprotein, Coronavirus/immunology ; Immunoglobulin Fab Fragments/immunology ; Animals ; Horses ; Workflow ; Neutralization Tests ; Enzyme-Linked Immunosorbent Assay ; Humans

Neutralizing epitope mapping for deltacoronavirus receptor-binding domain and seroepidemiological survey across different animal species.

Συγγραφείς: Li D; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China., Hao L; Luoyang Putai Biotechnology Co. Ltd, Luoyang, China., Huang B; Zhejiang Lab, Hangzhou, Zhejiang, China., Wang Z; Luoyang Putai Biotechnology Co. Ltd, Luoyang, China., Wang Z; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China., Guo M; Zhejiang Lab, Hangzhou, Zhejiang, China.; School of Life Sciences and Technology, Tongji University, Shanghai, China., Zhang Y; National Research Center for Veterinary Medicine, Luoyang, China., Deng J; Luoyang Putai Biotechnology Co. Ltd, Luoyang, China., Li Y; Luoyang Putai Biotechnology Co. Ltd, Luoyang, China., Zhao S; Luoyang Putai Biotechnology Co. Ltd, Luoyang, China., Tian K; National Research Center for Veterinary Medicine, Luoyang, China., Li X; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Jiangsu Key Laboratory of Zoonosis, Jiangsu Interdisciplinary Center for Zoonoses and Biosafety, Yangzhou University, Yangzhou, PR China.

Πηγή: Virulence [Virulence] 2026 Dec 31; Vol. 17 (1), pp. 2668161. Date of Electronic Publication: 2026 May 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Deltacoronavirus*/immunology , Deltacoronavirus*/genetics , Antibodies, Neutralizing*/immunology , Swine Diseases*/virology , Swine Diseases*/epidemiology , Swine Diseases*/immunology , Coronavirus Infections*/veterinary , Coronavirus Infections*/epidemiology , Coronavirus Infections*/virology , Coronavirus Infections*/immunology , Receptors, Virus*/immunology , Receptors, Virus*/metabolism , Epitope Mapping*, Antibodies, Monoclonal/immunology ; Antibodies, Viral/immunology ; Antibodies, Viral/blood ; Epitopes/immunology ; Enzyme-Linked Immunosorbent Assay/methods ; Animals ; Swine ; Seroepidemiologic Studies ; Neutralization Tests

HDX-MS-Guided computational modeling for rapid and accurate antibody-antigen interface mapping.

Συγγραφείς: McMahon W; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA., Zhang H; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Li X; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Oganesyan V; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Payne S; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Mehzabeen N; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Dyk NV; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Liu W; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Howard W; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA., Zhao P; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA., Zhang Y; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA., Fang M; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA., Chen X; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA., Mazor Y; Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA., Shi Y; Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA.

Πηγή: MAbs [MAbs] 2026 Dec; Vol. 18 (1), pp. 2722455. Date of Electronic Publication: 2026 Sep 11.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hydrogen Deuterium Exchange-Mass Spectrometry*/methods , Epitope Mapping*/methods , Epitopes*/chemistry , Epitopes*/immunology , Antigen-Antibody Complex*/chemistry , Antigen-Antibody Complex*/immunology, Immunoglobulin Fab Fragments/chemistry ; Humans ; Models, Molecular ; Crystallography, X-Ray

Mapping of C5-Blocking Monoclonal Antibodies Reveals New C5 Inhibitory Epitopes and Novel Modes of C5 Inhibition.

Συγγραφείς: Cooke RS; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Cardiff, UK., Lee KY; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Cardiff, UK., Menzies GE; Molecular Biosciences Division, School of Biosciences, Cardiff University, Cardiff, UK., Mizuno M; Department of Renal Replacement Therapy, Nagoya University Graduate School of Medicine, Nagoya, Japan., Morgan BP; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Cardiff, UK., Zelek WM; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Cardiff, UK.

Πηγή: Immunology [Immunology] 2026 Nov; Vol. 179 (3), pp. 444-456. Date of Electronic Publication: 2026 Jul 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Complement C5*/immunology , Complement C5*/antagonists & inhibitors , Complement C5*/metabolism , Antibodies, Monoclonal*/immunology , Antibodies, Monoclonal*/pharmacology , Epitopes*/immunology , Antibodies, Blocking*/immunology , Antibodies, Blocking*/pharmacology , Epitope Mapping*, Hemolysis/drug effects ; Antibodies, Monoclonal, Humanized/pharmacology ; Humans ; Animals ; Protein Binding

Mapping neutralizing epitopes and developing protective chimeric antibodies against porcine epidemic diarrhea virus infection.

Συγγραφείς: Sun M; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Sun Y; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Ma Z; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Wang Z; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Gao Y; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Sun H; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Bai J; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China., Wang X; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China. Electronic address: xwwang@njau.edu.cn., Jiang P; Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China; Jiangsu Co-innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, China. Electronic address: jiangp@njau.edu.cn.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jul; Vol. 371, pp. 152954. Date of Electronic Publication: 2026 Jun 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Porcine epidemic diarrhea virus*/immunology , Antibodies, Neutralizing*/immunology , Coronavirus Infections*/immunology , Coronavirus Infections*/veterinary , Coronavirus Infections*/prevention & control , Coronavirus Infections*/virology , Antibodies, Viral*/immunology , Swine Diseases*/immunology , Swine Diseases*/virology , Swine Diseases*/prevention & control , Epitopes*/immunology , Epitope Mapping*, Antibodies, Monoclonal/immunology ; Spike Glycoprotein, Coronavirus/immunology ; Animals ; Swine ; Mice ; Mice, Inbred BALB C ; Female

Antigenic mapping of H2 influenza viruses recognized by ferret and human sera and predicting antigenically significant sites.

Συγγραφείς: Reneer ZB; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Departments of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Ngyen C; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Departments of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Corn MR; School of Medicine, Mercer University, Savannah, Georgia, USA., Paugh JL; Medical College of Georgia, Augusta, Georgia, USA., Reynolds OC; Department of Computer Science, University of Georgia, Athens, Georgia, USA., O'Hara E; Augusta University/University of Georgia Medical Partnership, Athens, Georgia, USA., Ross TM; Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, Florida, USA.; Center for Vaccines and Immunology, University of Georgia, Athens, Georgia, USA., Baric RS; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Departments of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Πηγή: MSphere [mSphere] 2026 Jun 30; Vol. 11 (6), pp. e0002226. Date of Electronic Publication: 2026 Jun 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101674533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5042 (Electronic) Linking ISSN: 23795042 NLM ISO Abbreviation: mSphere Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hemagglutinin Glycoproteins, Influenza Virus*/immunology , Hemagglutinin Glycoproteins, Influenza Virus*/genetics , Influenza A Virus, H2N2 Subtype*/immunology , Influenza A Virus, H2N2 Subtype*/genetics , Antigens, Viral*/immunology , Antigens, Viral*/genetics , Antibodies, Viral*/blood , Antibodies, Viral*/immunology , Epitope Mapping*, Influenza Vaccines/immunology ; Influenza, Human/immunology ; Influenza, Human/virology ; Influenza, Human/prevention & control ; Orthomyxoviridae Infections/immunology ; Animals ; Ferrets ; Humans

Comprehensive mapping of identical sequences across human proteins emphasizes the widespread issue of shared epitopes in self-antigens.

Συγγραφείς: Kellermann G; Telomium SAS, Ivry-sur-Seine 94200, France., Croce O; Université Côte d'Azur, Institute for Research on Cancer and Aging, Nice (IRCAN), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut Hospitalo-Universitaire (IHU) RespirERA, Fédération Hospitalo-Universitaire (FHU) OncoAge, Nice, France., Mograbi B; Université Côte d'Azur, Institute for Research on Cancer and Aging, Nice (IRCAN), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut Hospitalo-Universitaire (IHU) RespirERA, Fédération Hospitalo-Universitaire (FHU) OncoAge, Nice, France., Hofman P; Université Côte d'Azur, Institute for Research on Cancer and Aging, Nice (IRCAN), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut Hospitalo-Universitaire (IHU) RespirERA, Fédération Hospitalo-Universitaire (FHU) OncoAge, Nice, France.; Laboratory of Clinical and Experimental Pathology, Centre Hospitalier Universitaire (CHU) de Nice, IHU RespirERA, FHU OncoAge, Biobank BB-0033-00025, Nice, France., Brest P; Université Côte d'Azur, Institute for Research on Cancer and Aging, Nice (IRCAN), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut Hospitalo-Universitaire (IHU) RespirERA, Fédération Hospitalo-Universitaire (FHU) OncoAge, Nice, France.

Πηγή: NAR genomics and bioinformatics [NAR Genom Bioinform] 2026 Jun 22; Vol. 8 (2), pp. lqag060. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 101756213 Publication Model: eCollection Cited Medium: Internet ISSN: 2631-9268 (Electronic) Linking ISSN: 26319268 NLM ISO Abbreviation: NAR Genom Bioinform Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Autoantigens*/immunology , Autoantigens*/chemistry , Autoantigens*/genetics , Epitopes*/immunology , Epitopes*/chemistry , Epitopes*/genetics , Epitope Mapping*/methods, Antigens, Neoplasm/immunology ; Antigens, Neoplasm/chemistry ; Antigens, Neoplasm/genetics ; Humans ; Animals ; Mice ; Amino Acid Sequence ; Immunoinformatics ; Software