Multiomics analyses revealed the roles of the epithelial-mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis.

Authors: Liu XC; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Liu GB; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Department of General and Trauma Surgery, Children's Hospital of Chongqing Medical University, Chongqing, China., Cheng C; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Zhu J; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Department of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, China.; Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, Chongqing, China.; Department of Pathology, Children's Hospital of Chongqing Medical University, Chongqing, China., Chen FF; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Ji Y; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Department of Laboratory, Children's Hospital of Chongqing Medical University, Chongqing, China., Zhang YN; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Yan XL; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Wang Q; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Li XY; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Ai Q; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., Shi Y; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China., He Y; Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.; National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing Municipal Health Commission Key Laboratory of Children's Vital Organ Development and Diseases, Chongqing, China.

Source: Clinical and translational medicine [Clin Transl Med] 2026 Sep; Vol. 16 (9), pp. e70793.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326 (Electronic) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med Subsets: MEDLINE

MeSH Terms: Enterocolitis, Necrotizing*/diagnosis , Enterocolitis, Necrotizing*/physiopathology , Biomarkers*/analysis , Biomarkers*/blood , Epithelial-Mesenchymal Transition*/physiology , Epithelial-Mesenchymal Transition*/genetics, Multiomics/methods ; Proteomics/methods ; Animals ; Mice ; Humans ; Infant, Newborn ; Disease Models, Animal ; Female

Hsa-mir-1293/GLI1/PTCH1 axis is involved in proliferation, migration, and EMT of laryngeal cancer.

Authors: Zhou Y; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China., Ren Y; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China; The First Affiliated Hospital of Guangxi Medical University, Department of Otolaryngology Head and Neck Surgery, Nanning, China., Chen Z; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China., Wan J; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China., She Y; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China., Tang Y; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China., Yang D; Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Department of Otolaryngology Head and Neck Surgery, Changsha, China., Guo H; Binhai New Area Hospital of Traditional Chinese Medicine, The Fourth Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China., Huang Z; Southern Medical University, School of Basic Medical Sciences, Cancer Research Institute, Guangzhou, China. Electronic address: zxhuang@smu.edu.cn.

Source: Brazilian journal of otorhinolaryngology [Braz J Otorhinolaryngol] 2026 Sep-Oct; Vol. 92 (5), pp. 101860. Date of Electronic Publication: 2026 Jul 22.

Publication Type: Journal Article

Journal Info: Publisher: E.N.T. Brazilian Society Country of Publication: Brazil NLM ID: 101207337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1808-8686 (Electronic) Linking ISSN: 18088686 NLM ISO Abbreviation: Braz J Otorhinolaryngol Subsets: MEDLINE

MeSH Terms: MicroRNAs*/metabolism , MicroRNAs*/genetics , MicroRNAs*/physiology , Zinc Finger Protein GLI1*/metabolism , Zinc Finger Protein GLI1*/genetics , Zinc Finger Protein GLI1*/physiology , Cell Proliferation*/genetics , Laryngeal Neoplasms*/pathology , Laryngeal Neoplasms*/genetics , Laryngeal Neoplasms*/metabolism , Cell Movement*/genetics , Cell Movement*/physiology , Epithelial-Mesenchymal Transition*/genetics , Epithelial-Mesenchymal Transition*/physiology , Patched-1 Receptor*/metabolism , Patched-1 Receptor*/genetics , Patched-1 Receptor*/physiology, Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Signal Transduction ; Neoplasm Invasiveness

Targeting CPSF73, the mRNA 3' end processing endonuclease, moves cancer cells away from the mesenchymal state.

Authors: Naseri M; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA, United States., Liu H; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA, United States., Wang L; The Wistar Institute, Philadelphia, PA, United States., Mostafa SM; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA, United States.; Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA, United States., Ranaei Pirmardan E; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA, United States., Tian B; The Wistar Institute, Philadelphia, PA, United States., Moore CL; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA, United States.; Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA, United States.

Source: Frontiers in immunology [Front Immunol] 2026 Aug 05; Vol. 17, pp. 1912261. Date of Electronic Publication: 2026 Aug 05 (Print Publication: 2026).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/genetics , Epithelial-Mesenchymal Transition*/drug effects , Cleavage And Polyadenylation Specificity Factor*/antagonists & inhibitors , Cleavage And Polyadenylation Specificity Factor*/metabolism , Cleavage And Polyadenylation Specificity Factor*/genetics , Neoplasms*/genetics , Neoplasms*/pathology , Neoplasms*/metabolism , RNA 3' End Processing*, RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Cell Proliferation/drug effects ; Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Polyadenylation ; 3' Untranslated Regions

SGLT2i-Triggered hyperglycosuria Unveils CDKN2A-Driven distal tubular senescence and EMT, Fueling renal fibrosis.

Authors: Chen Y; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Zheng SC; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Bai YF; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Deng WZ; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Gong N; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Fu YF; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Zhang ZY; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Chen XM; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China., Hong Q; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China. Electronic address: hongquan@301hospital.com.cn., Sun XF; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine(zyyzdxk-2023310), Beijing 100853, China; Medical School of Chinese PLA, Beijing 100853, China. Electronic address: xfssun@126.com.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Aug; Vol. 250 (Pt 1), pp. 117942. Date of Electronic Publication: 2026 Mar 31.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/drug effects , Epithelial-Mesenchymal Transition*/physiology , Cellular Senescence*/drug effects , Cellular Senescence*/physiology , Sodium-Glucose Transporter 2 Inhibitors*/toxicity , Cyclin-Dependent Kinase Inhibitor p16*/metabolism , Kidney Tubules, Distal*/drug effects , Kidney Tubules, Distal*/metabolism , Kidney Tubules, Distal*/pathology, Fibrosis/metabolism ; Fibrosis/chemically induced ; Benzhydryl Compounds/toxicity ; Glucosides/toxicity ; Glucosides/pharmacology ; Animals ; Mice, Inbred C57BL ; Mice ; Male ; Sodium-Glucose Transporter 2

IL1RAP promotes EMT and metastatic phenotypes in papillary thyroid carcinoma and is associated with PI3K/AKT signaling activation.

Authors: Zhao Y; Department of General Surgery, Chifeng Municipal Hospital, Inner Mongolia Medical University, No. 1 Zhaowuda Road, Hongshan District, Chifeng, Inner Mongolia, 024000, P.R. China., Shao Y; Department of General Surgery, Chifeng Municipal Hospital, Inner Mongolia Medical University, No. 1 Zhaowuda Road, Hongshan District, Chifeng, Inner Mongolia, 024000, P.R. China.; Baotou Medical College, No. 31 Jianshe Road, Donghe District, Baotou, Inner Mongolia, 014000, P.R. China., Guo Z; Department of General Surgery, Chifeng Municipal Hospital, Inner Mongolia Medical University, No. 1 Zhaowuda Road, Hongshan District, Chifeng, Inner Mongolia, 024000, P.R. China., Guo M; Department of General Surgery, Chifeng Municipal Hospital, Inner Mongolia Medical University, No. 1 Zhaowuda Road, Hongshan District, Chifeng, Inner Mongolia, 024000, P.R. China. myguo@cmu.edu.cn.; Research Institute of General Surgery, Affiliated Jinling Hospital of Medical School, Nanjing University, No. 305 Zhongshan East Road, Xuanwu District, Nanjing, Jiangsu, 210008, P.R. China. myguo@cmu.edu.cn.

Source: Medical oncology (Northwood, London, England) [Med Oncol] 2026 Oct 20; Vol. 43 (11). Date of Electronic Publication: 2026 Oct 20.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE

MeSH Terms: Proto-Oncogene Proteins c-akt*/metabolism , Thyroid Cancer, Papillary*/pathology , Thyroid Cancer, Papillary*/metabolism , Thyroid Cancer, Papillary*/genetics , Thyroid Neoplasms*/pathology , Thyroid Neoplasms*/metabolism , Thyroid Neoplasms*/genetics , Phosphatidylinositol 3-Kinases*/metabolism , Interleukin-1 Receptor Accessory Protein*/metabolism , Interleukin-1 Receptor Accessory Protein*/genetics , Epithelial-Mesenchymal Transition*, Biomarkers, Tumor/metabolism ; Humans ; Signal Transduction ; Female ; Male ; Cell Proliferation ; Cell Movement ; Prognosis ; Cell Line, Tumor ; Middle Aged ; Phenotype ; Gene Expression Regulation, Neoplastic ; Lymphatic Metastasis

SERPINB5 promotes pancreatic adenocarcinoma progression through FBXO32-mediated regulation of epithelial-mesenchymal transition.

Authors: Jiang H; Department of Hepatobiliary and Pancreatic Surgery, The Third People's Hospital of Yunnan Province, No. 292, Beijing Road, Guandu District, Kunming, Yunnan, 650200, China., Zhang PJ; Department of Neurosurgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110840, Liaoning, China., Li W; Department of Hepatobiliary and Pancreatic Surgery, The Third People's Hospital of Yunnan Province, No. 292, Beijing Road, Guandu District, Kunming, Yunnan, 650200, China., Zhang HF; Department of Neurosurgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110840, Liaoning, China. zhanghf615@163.com.

Source: Molecular biology reports [Mol Biol Rep] 2026 Oct 15; Vol. 53 (1). Date of Electronic Publication: 2026 Oct 15.

Publication Type: Journal Article

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/genetics , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Adenocarcinoma*/genetics , Adenocarcinoma*/pathology , Adenocarcinoma*/metabolism , Serpins*/genetics , Serpins*/metabolism , F-Box Proteins*/genetics , F-Box Proteins*/metabolism, Gene Expression Regulation, Neoplastic/genetics ; Cell Proliferation/genetics ; Cell Movement/genetics ; Humans ; Cell Line, Tumor ; Disease Progression ; Prognosis

Design, synthesis, and biological evaluation of secondary amine-containing flavonoids with anti-osteosarcoma activity associated with modulation of AKT signaling and EMT-related gene expression.

Authors: Santos I; LAQV, REQUIMTE, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal., Albuquerque HMT; LAQV, REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal., Ferreira de Oliveira JMP; LAQV, REQUIMTE, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal. Electronic address: jmoliveira@ff.up.pt., Fernandes E; LAQV, REQUIMTE, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal. Electronic address: egracas@ff.up.pt.

Source: Bioorganic chemistry [Bioorg Chem] 2026 Oct 05; Vol. 181, pp. 110433. Date of Electronic Publication: 2026 Aug 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH Terms: Flavonoids*/pharmacology , Flavonoids*/chemistry , Flavonoids*/chemical synthesis , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/antagonists & inhibitors , Osteosarcoma*/drug therapy , Osteosarcoma*/pathology , Osteosarcoma*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Amines*/chemistry , Amines*/pharmacology , Epithelial-Mesenchymal Transition*/drug effects , Epithelial-Mesenchymal Transition*/genetics , Drug Design*, Signal Transduction/drug effects ; Cell Proliferation/drug effects ; Humans ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Dose-Response Relationship, Drug ; Cell Line, Tumor

Novel VHL ligand-based PROTACs targeting JNK1: design, synthesis, and biological evaluation with potent anti-EMT activity.

Authors: Ren S; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China., Zhang Y; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China; Key Laboratory of Element Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Hao R; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China., Yuan J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China., Chi M; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China; Key Laboratory of Element Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Cai W; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China; Key Laboratory of Element Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Gu W; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China., Huang Y; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China; Key Laboratory of Element Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Yuan Y; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, TX 78229, USA., Chen X; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China; Key Laboratory of Element Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China. Electronic address: xch226@hznu.edu.cn., Ma L; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China. Electronic address: malei@ecust.edu.cn.

Source: Bioorganic chemistry [Bioorg Chem] 2026 Oct 05; Vol. 181, pp. 110388. Date of Electronic Publication: 2026 Aug 15.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/drug effects , Von Hippel-Lindau Tumor Suppressor Protein*/metabolism , Mitogen-Activated Protein Kinase 8*/metabolism , Mitogen-Activated Protein Kinase 8*/antagonists & inhibitors , Drug Design*, Indazoles/pharmacology ; Indazoles/chemical synthesis ; Indazoles/chemistry ; Humans ; Proteolysis Targeting Chimera ; Ligands ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug

SRGAP2-AS1 Regulates RSV Replication and EMT-Associated Changes Through PTBP1 and ZEB1.

Authors: Tan X; Zunyi Medical University, Zunyi, Guizhou, China.; Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China., Wu X; Zunyi Medical University, Zunyi, Guizhou, China.; Department of Critical Care Medicine, The Second People's Hospital of Guiyang (Jinyang Hospital)/The Affiliated Jinyang Hospital of Guizhou Medical University, Guiyang, China., Gao Y; Zunyi Medical University, Zunyi, Guizhou, China., Liu Y; Zunyi Medical University, Zunyi, Guizhou, China., Li Z; The First People's Hospital of Zunyi (The Third Affiliated Hospital of Zunyi Medical University), Zunyi, Guizhou, China., He G; Zunyi Medical University, Zunyi, Guizhou, China., Wu X; Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China., Peng X; Zunyi Medical University, Zunyi, Guizhou, China., Liu D; Zunyi Medical University, Zunyi, Guizhou, China.; Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.; NHC Key Laboratory of Pulmonary Immunological Diseases, Guiyang, Guizhou, China.

Source: Journal of medical virology [J Med Virol] 2026 Oct; Vol. 98 (10), pp. e71166.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

MeSH Terms: Zinc Finger E-box-Binding Homeobox 1*/metabolism , Zinc Finger E-box-Binding Homeobox 1*/genetics , Polypyrimidine Tract-Binding Protein*/metabolism , Polypyrimidine Tract-Binding Protein*/genetics , Heterogeneous-Nuclear Ribonucleoproteins*/metabolism , Heterogeneous-Nuclear Ribonucleoproteins*/genetics , Respiratory Syncytial Virus Infections*/virology , Respiratory Syncytial Virus Infections*/genetics , RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Respiratory Syncytial Virus, Human*/physiology , GTPase-Activating Proteins*/genetics , Respiratory Syncytial Viruses*/physiology , Epithelial-Mesenchymal Transition* , Virus Replication*, Epithelial Cells/virology ; Lung/virology ; Animals ; Humans ; Mice ; Cell Line ; Mice, Inbred BALB C ; Female

Deciphering the Role of ZEB1 as a Central Regulator of Epithelial-Mesenchymal Transition and Hormonal Resistance in Endometriosis.

Authors: Shirodkar S; Department of Pharmacology, SVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, 9819771515, India., Doshi G; Department of Pharmacology, SVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, 9819771515, India. gaurav.pharmacology@gmail.com.

Source: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2026 Oct; Vol. 33 (10), pp. 1954-1977. Date of Electronic Publication: 2026 Sep 09.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE

MeSH Terms: Zinc Finger E-box-Binding Homeobox 1*/metabolism , Zinc Finger E-box-Binding Homeobox 1*/genetics , Endometriosis*/metabolism , Endometriosis*/pathology , Endometriosis*/genetics , Epithelial-Mesenchymal Transition*/physiology , Endometrium*/metabolism , Endometrium*/pathology , Endometrium*/abnormalities, MicroRNAs/metabolism ; Humans ; Female ; Animals ; Signal Transduction ; Uterine Diseases

SCR Disease Name: Progesterone Resistance

KDM6A suppresses proliferation and epithelial-mesenchymal transition in prostate cancer cells.

Authors: Ni Y; Department of Urology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Lin Y; Department of Urology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Wang W; Department of Urology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Bao Y; Department of Urology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Chen J; Department of Urology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: zjdxcj1@126.com.

Source: Urologic oncology [Urol Oncol] 2026 Oct; Vol. 44 (10), pp. 652-661. Date of Electronic Publication: 2026 Aug 24.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9805460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2496 (Electronic) Linking ISSN: 10781439 NLM ISO Abbreviation: Urol Oncol Subsets: MEDLINE

MeSH Terms: Histone Demethylases*/metabolism , Histone Demethylases*/genetics , Prostatic Neoplasms, Castration-Resistant*/pathology , Prostatic Neoplasms, Castration-Resistant*/genetics , Prostatic Neoplasms, Castration-Resistant*/metabolism , Prostatic Neoplasms*/pathology , Epithelial-Mesenchymal Transition*, Male ; Humans ; Cell Proliferation ; Animals ; Cell Line, Tumor ; Mice ; Cell Movement ; Gene Expression Regulation, Neoplastic

Relationship between miRNAs dysregulation and the metastatic process associated with epithelial-mesenchymal transition in oral squamous cell carcinoma: A systematic review.

Authors: Lemos FLM; Department of Oral Pathology, School of Dentistry, Federal University of Pará, Av. Augusto Correa 01, Belém, PA, Brazil. Electronic address: leticiamalemos@gmail.com., Guimarães LHDS; Department of Oral Pathology, School of Dentistry, Federal University of Pará, Av. Augusto Correa 01, Belém, PA, Brazil. Electronic address: lena.guimaraes@ics.ufpa.br., Fagundes NCF; Mike Petryk School of Dentistry, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, 5488 Edmonton Clinic Health Academy, 11405 87 Ave NW, Edmonton, AB T6G 1C9, Canada. Electronic address: nf1@ualberta.ca., Pinheiro JJV; Department of Oral Pathology, School of Dentistry, Federal University of Pará, Av. Augusto Correa 01, Belém, PA, Brazil. Electronic address: joaopinheiro@ufpa.br., da Silva Kataoka MS; Department of Oral Pathology, School of Dentistry, Federal University of Pará, Av. Augusto Correa 01, Belém, PA, Brazil. Electronic address: skataoka@ufpa.br., Alves Júnior SM; Department of Oral Pathology, School of Dentistry, Federal University of Pará, Av. Augusto Correa 01, Belém, PA, Brazil. Electronic address: sergioalves@ufpa.br.

Source: Archives of oral biology [Arch Oral Biol] 2026 Oct; Vol. 190, pp. 106696. Date of Electronic Publication: 2026 Jul 15.

Publication Type: Journal Article; Systematic Review

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0116711 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1506 (Electronic) Linking ISSN: 00039969 NLM ISO Abbreviation: Arch Oral Biol Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/metabolism , Epithelial-Mesenchymal Transition*/genetics , Mouth Neoplasms*/pathology , Mouth Neoplasms*/genetics , Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/pathology, Neoplasm Metastasis/genetics ; Humans ; Gene Expression Regulation, Neoplastic ; Lymphatic Metastasis

ENOX1 promotes gastric cancer progression via Snail2-mediated epithelial-mesenchymal transition and M2-type tumour-associated macrophages polarisation.

Authors: Fu Q; Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining 810000, China., Di J; Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining 810000, China.. Electronic address: luosangdj@126.com.

Source: International immunopharmacology [Int Immunopharmacol] 2026 Oct 01; Vol. 186, pp. 117090. Date of Electronic Publication: 2026 Jul 04.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: Snail Family Transcription Factors*/metabolism , Snail Family Transcription Factors*/genetics , Stomach Neoplasms*/pathology , Stomach Neoplasms*/immunology , Stomach Neoplasms*/genetics , Stomach Neoplasms*/metabolism , Tumor-Associated Macrophages*/immunology , Tumor-Associated Macrophages*/metabolism , Epithelial-Mesenchymal Transition*, Humans ; Animals ; Cell Line, Tumor ; Mice ; Tumor Microenvironment ; Disease Progression ; Female ; Male ; Gene Expression Regulation, Neoplastic ; Cell Movement

The role of TRAF6 in regulating MAP3K7/P38/MAPK pathway in the epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy.

Authors: Chen Z; Department of Ophthalmology, The First People's Hospital of Yunnan Province, Kunming 650032, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China., Yang Z; Department of Ophthalmology, The First People's Hospital of Yunnan Province, Kunming 650032, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China., Hu Z; Department of Ophthalmology, The First People's Hospital of Yunnan Province, Kunming 650032, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China., Lei M; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China., Li Q; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China., Zhang W; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China., Chen L; Department of Ophthalmology, The First People's Hospital of Yunnan Province, Kunming 650032, China., Su Y; Department of Ophthalmology, The First People's Hospital of Yunnan Province, Kunming 650032, China., Ni N; Department of Ophthalmology, The First People's Hospital of Yunnan Province, Kunming 650032, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650500, China. Electronic address: nnh1972@163.com.

Source: Cellular signalling [Cell Signal] 2026 Oct; Vol. 146, pp. 112670. Date of Electronic Publication: 2026 Jun 12.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

MeSH Terms: TNF Receptor-Associated Factor 6*/metabolism , TNF Receptor-Associated Factor 6*/genetics , Vitreoretinopathy, Proliferative*/metabolism , Vitreoretinopathy, Proliferative*/pathology , Retinal Pigment Epithelium*/metabolism , Retinal Pigment Epithelium*/pathology , p38 Mitogen-Activated Protein Kinases*/metabolism , Epithelial-Mesenchymal Transition* , MAP Kinase Signaling System*, MAP Kinase Kinase Kinase 7/metabolism ; Epithelial Cells/metabolism ; Animals ; Humans ; Mice ; Cell Line ; Transforming Growth Factor beta1 ; Mice, Inbred C57BL ; Disease Models, Animal ; Intracellular Signaling Peptides and Proteins

Hedyotis diffusa Willd-Scutellaria barbata D.Don Suppresses Colorectal Cancer Liver Metastasis by Targeting hsa_circ_0039933-Mediated Epithelial-Mesenchymal Transition.

Authors: Yuan S; Department of Traditional Chinese Medicine, Ganzhou People's Hospital, No.16, Meiguan Avenue, Zhanggong District, Ganzhou City, 341000, Jiangxi Province, China., Li S; Department of Traditional Chinese Medicine, Ganzhou People's Hospital, No.16, Meiguan Avenue, Zhanggong District, Ganzhou City, 341000, Jiangxi Province, China., Chen C; Department of Traditional Chinese Medicine, Ganzhou People's Hospital, No.16, Meiguan Avenue, Zhanggong District, Ganzhou City, 341000, Jiangxi Province, China. c15793478243@126.com.

Source: Biochemical genetics [Biochem Genet] 2026 Oct; Vol. 64 (5), pp. 7608-7627. Date of Electronic Publication: 2026 Jun 08.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0126611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4927 (Electronic) Linking ISSN: 00062928 NLM ISO Abbreviation: Biochem Genet Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/metabolism , Epithelial-Mesenchymal Transition*/drug effects , Liver Neoplasms*/secondary , Liver Neoplasms*/drug therapy , Liver Neoplasms*/genetics , Liver Neoplasms*/metabolism , Hedyotis*/chemistry , RNA, Circular*/genetics , RNA, Circular*/metabolism , Drugs, Chinese Herbal*/pharmacology, Cell Proliferation/drug effects ; Cell Movement/drug effects ; Animals ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Cell Line, Tumor ; Male

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial-mesenchymal transition and pulmonary niche formation of breast cancer.

Authors: Lu J; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Shirazi Nia R; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Sun J; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China., Filippopoulou C; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., De Vega D; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Hu P; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China., Liang H; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Yao H; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Pan C; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Wu X; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Gu X; Department of Breast Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Xie X; Department of Breast Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China., Giamas G; International Oncology Institute, The First Affiliated Hospital of Zhejiang Chinese Medical University, Oncology Department of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China.; Department of Biochemistry and Biomedicine, School of Life Sciences, University of Sussex, Brighton, UK.

Source: Biological reviews of the Cambridge Philosophical Society [Biol Rev Camb Philos Soc] 2026 Oct; Vol. 101 (5), pp. 2103-2118. Date of Electronic Publication: 2026 Apr 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Cambridge University Press Country of Publication: England NLM ID: 0414576 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-185X (Electronic) Linking ISSN: 00063231 NLM ISO Abbreviation: Biol Rev Camb Philos Soc Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/physiology , Extracellular Vesicles*/physiology , Breast Neoplasms*/pathology , Lung Neoplasms*/secondary, Humans ; Animals ; Female ; Tumor Microenvironment ; Neoplasm Metastasis

Acupuncture inhibits ferroptosis and epithelial-mesenchymal transition to attenuate proteinuria in diabetic kidney disease.

Authors: Zhang P; Department 1 of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi Province 710003, China., Song A; Department 1 of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi Province 710003, China., Tian Y; Department 1 of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi Province 710003, China., Shao D; Department of Acupuncture, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi Province 710003, China. Electronic address: q654285623@163.com.

Source: Tissue & cell [Tissue Cell] 2026 Oct; Vol. 102, pp. 103530. Date of Electronic Publication: 2026 Apr 10.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH Terms: Diabetic Nephropathies*/therapy , Diabetic Nephropathies*/pathology , Diabetic Nephropathies*/complications , Proteinuria*/therapy , Proteinuria*/pathology , Proteinuria*/complications , Epithelial-Mesenchymal Transition* , Ferroptosis* , Acupuncture Therapy*, Animals ; Male ; Rats ; Rats, Sprague-Dawley

PTBP3 promotes diabetic nephropathy via Smad3-dependent podocyte-mesenchymal transition.

Authors: Li Y; Department of Nephrology, the First Affiliated Hospital of Harbin Medical University, Harbin, China., Fu Y; Department of Nephrology, the First Affiliated Hospital of Harbin Medical University, Harbin, China., Wang X; Department of Nephrology, the First Affiliated Hospital of Harbin Medical University, Harbin, China., Ma X; Department of Nephrology, the First Affiliated Hospital of Harbin Medical University, Harbin, China., Cong G; Department of Nephrology, the First Affiliated Hospital of Harbin Medical University, Harbin, China., Sui M; Department of Nephrology, the First Affiliated Hospital of Harbin Medical University, Harbin, China. suimanshu@163.com.

Source: Molecular biology reports [Mol Biol Rep] 2026 Sep 27; Vol. 53 (1). Date of Electronic Publication: 2026 Sep 27.

Publication Type: Journal Article

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

MeSH Terms: Diabetic Nephropathies*/metabolism , Diabetic Nephropathies*/genetics , Diabetic Nephropathies*/pathology , Podocytes*/metabolism , Podocytes*/pathology , Smad3 Protein*/metabolism , Smad3 Protein*/genetics , Epithelial-Mesenchymal Transition*/genetics , Polypyrimidine Tract-Binding Protein*/metabolism , Polypyrimidine Tract-Binding Protein*/genetics, Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/genetics ; Animals ; Mice ; Male ; Fibrosis ; Mice, Inbred C57BL ; Humans

SLC35D1 Is Associated with Colorectal Cancer Progression, EMT-Related Phenotypes, and Immune Infiltration.

Authors: Chang YJ; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Center for Precision Medicine and Translational Cancer Research, Department of Medical Research, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan.; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 116079, Taiwan.; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 116079, Taiwan., Tsai KY; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Division of General Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235041, Taiwan., Zumbi CN; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Lee CC; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Prince GMSH; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Batzorig U; Department of Dermatology, Department of Cellular and Molecular Medicine, UCSD Stem Cell Program, University of California, San Diego, La Jolla, CA 92093, USA., Huang CY; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 116079, Taiwan.; School of Medicine, National Tsing Hua University, Hsinchu 300044, Taiwan.; Institute of Molecular and Cellular Biology, National Tsing Hua University, Hsinchu 300044, Taiwan., Wei PL; Center for Precision Medicine and Translational Cancer Research, Department of Medical Research, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan.; Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei 11031, Taiwan.; Taipei Cancer Center, Taipei Medical University, Taipei 11031, Taiwan.

Source: International journal of molecular sciences [Int J Mol Sci] 2026 Sep 24; Vol. 27 (19). Date of Electronic Publication: 2026 Sep 24.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/immunology , Colorectal Neoplasms*/metabolism , Epithelial-Mesenchymal Transition*/genetics, Cell Proliferation/genetics ; Cell Movement/genetics ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Humans ; Gene Expression Regulation, Neoplastic ; Prognosis ; Disease Progression ; Phenotype ; Cell Line, Tumor ; Female

[MIS18BP1 regulates epithelial-mesenchymal transition, proliferation, and migration of renal cancer cells via the PI3K/AKT pathway].

Authors: Zhao B; Department of Pathogenic Biology, School of Basic Medical Sciences, Qingdao University, Qingdao 266071, China.; Department of Clinical Laboratory, Qingdao Municipal Hospital, Qingdao 266011, China., Tan X; Department of Clinical Laboratory, Qingdao Municipal Hospital, Qingdao 266011, China., Liang X; Department of Clinical Laboratory, Qingdao Municipal Hospital, Qingdao 266011, China.; College of Medical Laboratory Science, Shandong Second Medical University, Weifang 261053, China., Pan Y; Department of Clinical Laboratory, Qingdao Municipal Hospital, Qingdao 266011, China.; College of Medical Laboratory Science, Shandong Second Medical University, Weifang 261053, China., Yuan J; Department of Clinical Laboratory, Qingdao Municipal Hospital, Qingdao 266011, China., Song W; Department of Clinical Laboratory, Qingdao Municipal Hospital, Qingdao 266011, China.

Source: Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2026 Sept 20; Vol. 46 (9), pp. 2159-2172.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Nanfang yi ke da xue xue bao bian ji bu Country of Publication: China NLM ID: 101266132 Publication Model: Print Cited Medium: Print ISSN: 1673-4254 (Print) Linking ISSN: 16734254 NLM ISO Abbreviation: Nan Fang Yi Ke Da Xue Xue Bao Subsets: MEDLINE

MeSH Terms: Kidney Neoplasms*/metabolism , Kidney Neoplasms*/pathology , Carcinoma, Renal Cell*/metabolism , Carcinoma, Renal Cell*/pathology , Epithelial-Mesenchymal Transition*, Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Humans ; Cell Proliferation ; Cell Movement ; Cell Line, Tumor ; Signal Transduction ; Gene Expression Regulation, Neoplastic ; Female