ATG9A controls all stages of autophagosome biogenesis

Συγγραφείς: Ruheena Javed, Muriel Mari, Einar Trosdal, Thabata Lopes Alberto Duque, Masroor Paddar, Lee Allers, Prithvi Akepati, Michal H. Mudd, Fulvio Reggiori, Vojo Deretic

Πηγή: Javed, R, Mari, M, Trosdal, E, Lopes Alberto Duque, T, Paddar, M, Allers, L, Akepati, P, Mudd, M H, Reggiori, F & Deretic, V 2025, 'ATG9A controls all stages of autophagosome biogenesis', Autophagy, vol. 21, no. 8, pp. 1859-1861. https://doi.org/10.1080/15548627.2025.2494802

Θεματικοί όροι: Mice, Endosomal Sorting Complexes Required for Transport/metabolism, Autophagy-Related Proteins/metabolism, Vesicular Transport Proteins/metabolism, Humans, Animals, Autophagosomes/metabolism, Membrane Proteins/metabolism, Autophagy/physiology, HeLa Cells

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40241347

ATG9A facilitates the closure of mammalian autophagosomes

Συγγραφείς: Ruheena Javed, Muriel Mari, Einar Trosdal, Thabata Duque, Masroor Ahmad Paddar, Lee Allers, Michal H. Mudd, Aurore Claude-Taupin, Prithvi Reddy Akepati, Emily Hendrix, Yi He, Michelle Salemi, Brett Phinney, Yasuo Uchiyama, Fulvio Reggiori, Vojo Deretic

Πηγή: J Cell Biol
Javed, R, Mari, M, Trosdal, E, Duque, T, Paddar, M A, Allers, L, Mudd, M H, Claude-Taupin, A, Akepati, P R, Hendrix, E, He, Y, Salemi, M, Phinney, B, Uchiyama, Y, Reggiori, F & Deretic, V 2025, 'ATG9A facilitates the closure of mammalian autophagosomes', The Journal of Cell Biology, vol. 224, no. 2, e202404047. https://doi.org/10.1083/jcb.202404047

Θεματικοί όροι: Endosomal Sorting Complexes Required for Transport/metabolism, Endosomal Sorting Complexes Required for Transport, Autophagy-Related Proteins/metabolism, Autophagosomes, Vesicular Transport Proteins, Autophagy-Related Proteins, Membrane Proteins, Lysosomes/metabolism, Article, Mice, HEK293 Cells, Vesicular Transport Proteins/metabolism, Autophagy, Humans, Animals, Autophagosomes/metabolism, Membrane Proteins/metabolism, Lysosomes, HeLa Cells

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/39745851
http://www.scopus.com/inward/record.url?scp=85214484109&partnerID=8YFLogxK
https://doi.org/10.1083/jcb.202404047
https://pure.au.dk/portal/en/publications/82aac68c-f90a-4a52-8aa7-ab32afe75cbd

Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains

Συγγραφείς: Hideyuki Shimizu, Samira Hosseini-Alghaderi, Simon A. Woodcock, Martin Baron

Πηγή: J Cell Biol
Shimizu, H, Hosseini Alghaderi, S S, Woodcock, S & Baron, M 2024, 'Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains', Journal of Cell Biology, vol. 223, no. 5, e202211041. https://doi.org/10.1083/jcb.202211041

Θεματικοί όροι: 0301 basic medicine, Receptors, Notch/metabolism, Drosophila Proteins/metabolism, ResearchInstitutes_Networks_Beacons/03/03, name=Cancer, Down-Regulation, Membrane Microdomains/metabolism, Endosomes, Article, ADAM10 Protein, 03 medical and health sciences, Transient Receptor Potential Channels, Membrane Microdomains, Receptors, Notch/metabolism, Animals, Drosophila Proteins, Cancer, 0303 health sciences, Endosomal Sorting Complexes Required for Transport/metabolism, Manchester Cancer Research Centre, Endosomal Sorting Complexes Required for Transport, Receptors, Notch, Clathrin/metabolism, Ubiquitination, ADAM10 Protein/metabolism, Membrane Proteins, Endosomes/metabolism, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre, Clathrin, Membrane Proteins/metabolism, Drosophila

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/38358349
https://research.manchester.ac.uk/en/publications/c1be051f-d2e6-43c0-8c43-fd8dbce37b43
https://doi.org/10.1083/jcb.202211041
https://www.mendeley.com/catalogue/98c9f327-2d07-35bd-a1c9-a96df1168752/
http://www.scopus.com/inward/record.url?scp=85185347504&partnerID=8YFLogxK
https://research.manchester.ac.uk/en/publications/c1be051f-d2e6-43c0-8c43-fd8dbce37b43
https://doi.org/10.1083/jcb.202211041

Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs

Συγγραφείς: Ruheena Javed, Ashish Jain, Thabata Duque, Emily Hendrix, Masroor Ahmad Paddar, Sajjad Khan, Aurore Claude‐Taupin, Jingyue Jia, Lee Allers, Fulong Wang, Michal Mudd, Graham Timmins, Keith Lidke, Tor Erik Rusten, Prithvi Reddy Akepati, Yi He, Fulvio Reggiori, Eeva‐Liisa Eskelinen, Vojo Deretic

Πηγή: Javed, R, Jain, A, Duque, T, Hendrix, E, Paddar, M A, Khan, S, Claude-Taupin, A, Jia, J, Allers, L, Wang, F, Mudd, M, Timmins, G, Lidke, K, Rusten, T E, Akepati, P R, He, Y, Reggiori, F, Eskelinen, E-L & Deretic, V 2023, 'Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs', The EMBO Journal, vol. 42, no. 14, e112845. https://doi.org/10.15252/embj.2022112845

Θεματικοί όροι: Mammals, amphisome, autophagy, Endosomal Sorting Complexes Required for Transport/metabolism, Endosomal Sorting Complexes Required for Transport, ta1182, Autophagosomes, Autophagy-Related Protein 8 Family, Microtubule-Associated Proteins/genetics, ta3111, ESCRT, Autophagy-Related Protein 8 Family/genetics, LC3, Autophagy, Animals, Humans, Autophagosomes/metabolism, ATG8, Microtubule-Associated Proteins

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/37272163
http://juuli.fi/Record/0669364023
https://doi.org/10.15252/embj.2022112845
https://pure.au.dk/portal/en/publications/4cfd37d1-8aaa-4025-9f68-b91efad96a58
https://doi.org/10.15252/embj.2022112845
http://www.scopus.com/inward/record.url?scp=85160827693&partnerID=8YFLogxK

USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons.

Συγγραφείς: Mauri, Sofia, Bernardo, Greta, Martinez, Aitor, Favaro, Mariavittoria, Trevisan, Marta, Cobraiville, Gaël, Fillet, Marianne, Caicci, Federico, Whitworth, Alexander J, Ziviani, Elena

Συνεισφορές: CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège

Πηγή: Cells, 12 (8), 1143 (2023-04-13)

Θεματικοί όροι: DUBs, Parkin, USP8, autophagy, mitophagy, Ubiquitin-Protein Ligases, Protein Kinases, USP8 protein, human, Endopeptidases, Ubiquitin Thiolesterase, Endosomal Sorting Complexes Required for Transport, PINK1 protein, Drosophila, Protein Serine-Threonine Kinases, Drosophila Proteins, Animals, Humans, Down-Regulation, Drosophila/metabolism, Drosophila melanogaster/metabolism, Ubiquitin-Protein Ligases/metabolism, Protein Kinases/metabolism, Brain/metabolism, Neurons/metabolism, Endopeptidases/metabolism, Ubiquitin Thiolesterase/metabolism, Endosomal Sorting Complexes Required for Transport/metabolism, Protein Serine-Threonine Kinases/metabolism, Mitophagy/genetics, Drosophila Proteins/metabolism, Brain, Drosophila, Drosophila melanogaster, Neurons, Biochemistry, Genetics and Molecular Biology (all), General Medicine, Human health sciences, Pharmacy, pharmacology & toxicology, Sciences de la santé humaine, Pharmacie, pharmacologie & toxicologie

Relation: https://www.mdpi.com/2073-4409/12/8/1143/pdf; urn:issn:2073-4409

Σύνδεσμος πρόσβασης: https://orbi.uliege.be/handle/2268/316584

The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division

Συγγραφείς: Hurtig, Fredrik, Burgers, Thomas C. Q., Cezanne, Alice, Jiang, Xiuyun, Mol, Frank N., Traparić, Jovan, Pulschen, Andre Arashiro, Nierhaus, Tim, Tarrason-Risa, Gabriel, Harker-Kirschneck, Lena, Löwe, Jan, Šarić, Anđela, Vlijm, Rifka, Baum, Buzz

Πηγή: Sci Adv
Science Advances

Θεματικοί όροι: Endosomal Sorting Complexes Required for Transport/metabolism, Endosomal Sorting Complexes Required for Transport, Polymers, Biomedicine and Life Sciences, Archaea/metabolism, Archaea, Cell Division

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/36921039
https://research.rug.nl/en/publications/088b4170-e0d2-4cfd-8faf-d32e85de39fd
https://hdl.handle.net/11370/088b4170-e0d2-4cfd-8faf-d32e85de39fd
https://doi.org/10.1126/sciadv.ade5224

Exploring Extracellular Vesicles Biogenesis in Hypothalamic Cells through a Heavy Isotope Pulse/Trace Proteomic Approach.

Συγγραφείς: Tan, C.F., Teo, H.S., Park, J.E., Dutta, B., Tse, S.W., Leow, M.K., Wahli, W., Sze, S.K.

Θεματικοί όροι: Animals, Cathepsins/metabolism, Cell Line, Cluster Analysis, Endosomal Sorting Complexes Required for Transport/metabolism, Extracellular Vesicles/metabolism, Extracellular Vesicles/ultrastructure, Gene Ontology, Hypothalamus/cytology, Isotopes/metabolism, Lysosomes/metabolism, Mice, Protein Biosynthesis, Proteome/metabolism, Proteomics/methods, cathepsin, energy homeostasis, extracellular vesicles, extracellular vesicles biogenesis, hypothalamus, pulsed-SILAC

Περιγραφή αρχείου: application/pdf

Relation: Cells; https://iris.unil.ch/handle/iris/34562; serval:BIB_38F5E271C09D; 000539340200254

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/34562
https://doi.org/10.3390/cells9051320

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.

Συγγραφείς: Rühl, S., Shkarina, K., Demarco, B., Heilig, R., Santos, J.C., Broz, P.

Θεματικοί όροι: Aniline Compounds/metabolism, Animals, Apoptosis Regulatory Proteins/genetics, Apoptosis Regulatory Proteins/metabolism, Calcium/metabolism, Calcium Signaling, Caspase 1/metabolism, Caspases/genetics, Caspases/metabolism, Cell Membrane/metabolism, Cell Survival, Cells, Cultured, Endosomal Sorting Complexes Required for Transport/metabolism, Fluorescent Dyes/metabolism, HEK293 Cells, Humans, Inflammation/metabolism, Inflammation/pathology, Interleukin-1beta/metabolism, Macrophages, Mice, Neoplasm Proteins/genetics, Neoplasm Proteins/metabolism, Pyroptosis, Xanthenes/metabolism

Περιγραφή αρχείου: application/pdf

Relation: Science; https://iris.unil.ch/handle/iris/253075; serval:BIB_EC1D001C7201; 000451124500045

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/253075
https://doi.org/10.1126/science.aar7607

Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.

Συγγραφείς: Al-Qusairi, L., Basquin, D., Roy, A., Stifanelli, M., Rajaram, R.D., Debonneville, A., Nita, I., Maillard, M., Loffing, J., Subramanya, A.R., Staub, O.

Θεματικοί όροι: Amino Acid Sequence, Animals, Antibodies, Blocking/pharmacology, Diet, Endosomal Sorting Complexes Required for Transport/metabolism, Epithelial Sodium Channels/metabolism, Gene Expression Regulation, Immediate-Early Proteins/deficiency, Immediate-Early Proteins/genetics, Kidney Tubules/metabolism, Male, Mice, Knockout, Minor Histocompatibility Antigens/metabolism, Potassium/urine, Potassium Channels, Inwardly Rectifying/antagonists & inhibitors, Inwardly Rectifying/immunology, Potassium, Dietary/pharmacology, Protein-Serine-Threonine Kinases/deficiency, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/metabolism, Ubiquitin-Protein Ligases/metabolism, aldosterone, epithelial Na+ channel, epithelial transport, neural precursor cell expressed developmentally downregulated protein 4-2, phosphorylation

Περιγραφή αρχείου: application/pdf

Relation: American Journal of Physiology - Renal Physiology; https://iris.unil.ch/handle/iris/217524; serval:BIB_C34743F0B828; 000384976500011

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/217524
https://doi.org/10.1152/ajprenal.00002.2016

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.

Συγγραφείς: Roy, A., Al-Qusairi, L., Donnelly, B.F., Ronzaud, C., Marciszyn, A.L., Gong, F., Chang, Y.P., Butterworth, M.B., Pastor-Soler, N.M., Hallows, K.R., Staub, O., Subramanya, A.R.

Θεματικοί όροι: Aldosterone/pharmacology, Alternative Splicing/drug effects, Alternative Splicing/physiology, Animals, Endosomal Sorting Complexes Required for Transport/genetics, Endosomal Sorting Complexes Required for Transport/metabolism, Enzyme Activation/drug effects, Enzyme Activation/physiology, Gene Expression Regulation, Enzymologic/drug effects, Enzymologic/physiology, HEK293 Cells, Humans, Intracellular Signaling Peptides and Proteins/biosynthesis, Intracellular Signaling Peptides and Proteins/genetics, Mice, Knockout, Minor Histocompatibility Antigens, Nedd4 Ubiquitin Protein Ligases, Protein Serine-Threonine Kinases/biosynthesis, Protein Serine-Threonine Kinases/genetics, Protein Serine-Threonine Kinases/metabolism, Signal Transduction/drug effects, Signal Transduction/physiology, Ubiquitin-Protein Ligases/genetics, Ubiquitin-Protein Ligases/metabolism, WNK Lysine-Deficient Protein Kinase 1

Relation: The Journal of Clinical Investigation; https://iris.unil.ch/handle/iris/167752; serval:BIB_689620E22F3F; 000362303600021

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/167752
https://doi.org/10.1172/JCI75245

Intracellular ubiquitylation of the epithelial Na+ channel controls extracellular proteolytic channel activation via conformational change.

Συγγραφείς: Ruffieux-Daidié, D., Staub, O.

Θεματικοί όροι: Amino Acid Motifs, Chymotrypsin/pharmacology, Endopeptidases/genetics, Endopeptidases/metabolism, Endosomal Sorting Complexes Required for Transport/genetics, Endosomal Sorting Complexes Required for Transport/metabolism, Epithelial Sodium Channel/genetics, Epithelial Sodium Channel/metabolism, Furin/genetics, Furin/metabolism, HEK293 Cells, Humans, Mutation, Signal Transduction/drug effects, Signal Transduction/physiology, Trypsin/pharmacology, Ubiquitin-Protein Ligases/genetics, Ubiquitin-Protein Ligases/metabolism, Ubiquitination/drug effects, Ubiquitination/physiology

Relation: Journal of Biological Chemistry; https://iris.unil.ch/handle/iris/145751; serval:BIB_A490D71A413D; 000286464300005

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/145751
https://doi.org/10.1074/jbc.M110.176156

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.

Συγγραφείς: Arroyo, J.P., Lagnaz, D., Ronzaud, C., Vázquez, N., Ko, B.S., Moddes, L., Ruffieux-Daidié, D., Hausel, P., Koesters, R., Yang, B., Stokes, J.B., Hoover, R.S., Gamba, G., Staub, O.

Θεματικοί όροι: 11-beta-Hydroxysteroid Dehydrogenase Type 2/metabolism, Aldosterone/metabolism, Animals, Down-Regulation, Endosomal Sorting Complexes Required for Transport/metabolism, HEK293 Cells, Humans, Immediate-Early Proteins/metabolism, Kidney Tubules, Distal/enzymology, Mice, Knockout, Phosphorylation, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction, Sodium Chloride Symporters/metabolism, Ubiquitin-Protein Ligases/metabolism, Ubiquitination, Xenopus laevis

Relation: Journal of the American Society of Nephrology; https://iris.unil.ch/handle/iris/141500; serval:BIB_C55A6EC97B43; 000295705800018

Διαθεσιμότητα: https://iris.unil.ch/handle/iris/141500
https://doi.org/10.1681/ASN.2011020132

Function of ceramide transfer protein for biogenesis and sphingolipid composition of extracellular vesicles

Συγγραφείς: Simone M. Crivelli, Caterina Giovagnoni, Zhihui Zhu, Priyanka Tripathi, Ahmed Elsherbini, Zainuddin Quadri, Jian Pu, Liping Zhang, Branislav Ferko, Dusan Berkes, Stefka D. Spassieva, Pilar Martinez‐Martinez, Erhard Bieberich

Πηγή: J Extracell Vesicles
Journal of Extracellular Vesicles, Vol 11, Iss 6, Pp n/a-n/a (2022)

Θεματικοί όροι: 0301 basic medicine, PI4KIII beta-IN-10, PI4KIII beta, HPA-12, ENDOPLASMIC-RETICULUM, EFFICIENT, BIOLOGY, ER‐endosome contact sites, Protein Serine-Threonine Kinases, Ceramides, sphingomyelin, HPA‐12, Extracellular Vesicles, 03 medical and health sciences, ER-endosome contact sites, TRAFFICKING, ceramide, AlphaFold2, CERT, IN-VIVO, Research Articles, MICRODOMAINS, EXOSOMES, Tsg101, Sphingolipids, 0303 health sciences, Endosomal Sorting Complexes Required for Transport/metabolism, QH573-671, Endosomal Sorting Complexes Required for Transport, TRANSPORTER, INHIBITOR, Extracellular Vesicles/metabolism, PI4P, PI4KII alpha, NC03, extracellular vesicles, Cytology, Carrier Proteins

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/35642450
https://doaj.org/article/35b1989cf24d4976b8e5455fb4bc0a1f

The Bul1/2 Alpha-Arrestins Promote Ubiquitylation and Endocytosis of the Can1 Permease upon Cycloheximide-Induced TORC1-Hyperactivation.

Συγγραφείς: Megarioti, Amalia A.H., Primo Planta, Cecilia, Kapetanakis, Georgios, Athanasopoulos, Alexandros, Sophianopoulou, Vicky, André, Bruno, Gournas, Christos

Πηγή: International journal of molecular sciences, 22 (19

Θεματικοί όροι: Sciences bio-médicales et agricoles, Adaptor Proteins, Signal Transducing -- metabolism, Amino Acid Transport Systems, Basic -- metabolism, Antifungal Agents -- pharmacology, Cycloheximide -- pharmacology, Endocytosis -- drug effects, Endosomal Sorting Complexes Required for Transport -- metabolism, Gene Expression Regulation, Fungal -- genetics, Protein Transport -- drug effects, Saccharomyces cerevisiae -- metabolism, Saccharomyces cerevisiae Proteins -- metabolism, Transcription Factors -- metabolism, Ubiquitin-Protein Ligase Complexes -- metabolism, Ubiquitin-Protein Ligases -- metabolism, Ubiquitination -- drug effects, Nedd4, Npr1, Target of Rapamycin Complex 1, acidic patch, arginine, endocytosis, transporter, ubiquitin, α-arrestin

Περιγραφή αρχείου: 1 full-text file(s): application/pdf

Relation: uri/info:doi/10.3390/ijms221910208; uri/info:pii/ijms221910208; uri/info:pmid/34638549; uri/info:scp/85115352345; uri/info:pmcid/PMC8508209

Διαθεσιμότητα: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/336742
https://dipot.ulb.ac.be/dspace/bitstream/2013/336742/3/ijms-22-10208-v2.pdf

CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

Συγγραφείς: Hwanhee Oh, Jung-Min Kim, Changchun Xiao, Dorothy Hu, Sutada Lotinun, Kwang Hwan Park, Matthew B. Greenblatt, Sankar Ghosh, Jae-Hyuck Shim, Jin Woo Lee, Josef M. Penninger, Roland Baron, Anju Singh, Dong Yeon Shin, Jae Myun Lee, Julia F. Charles, Ki-Young Lee

Συνεισφορές: Matthew B. Greenblatt, Kwang Hwan Park, Hwanhee Oh, Jung Min Kim, Dong Yeon Shin, Jae Myun Lee, Jin Woo Lee, Anju Singh, Ki young Lee, Dorothy Hu, Changchun Xiao, Julia F. Charles, Josef M. Penninger, Sutada Lotinun, Roland Baron, Sankar Ghosh, Jae Hyuck Shim, Park, Kwang Hwan, Lee, Jae Myun, Lee, Jin Woo

Πηγή: J Exp Med
Journal of Experimental Medicine

Θεματικοί όροι: 0301 basic medicine, I-kappa B Proteins/metabolism, Immunoblotting, Molecular Sequence Data, Fluorescent Antibody Technique, Cell Cycle Proteins, Mice, Transgenic, Osteoclasts/metabolism, Transgenic, Article, Mice, 03 medical and health sciences, NF-KappaB Inhibitor alpha, Valosin Containing Protein, Cell Differentiation/physiology, Animals, Humans, Bone Development/physiology, Luciferases, In Situ Hybridization, DNA Primers, Adenosine Triphosphatases, DNA Primers/genetics, 0303 health sciences, Bone Development, Cell Cycle Proteins/metabolism, Base Sequence, Endosomal Sorting Complexes Required for Transport, Reverse Transcriptase Polymerase Chain Reaction, Bone Development/genetics, Osteoblasts/cytology, Ubiquitination, Cell Differentiation, Adenosine Triphosphatases/metabolism, NF-kappa B/metabolism, RANK Ligand/metabolism, Immunohistochemistry, 3. Good health, Endosomal Sorting Complexes Required for Transport/metabolism, HEK293 Cells, Signal Transduction/physiology, RNA, I-kappa B Proteins, Sequence Analysis

Περιγραφή αρχείου: 1283~1301; application/pdf

Σύνδεσμος πρόσβασης: https://europepmc.org/articles/pmc4516796?pdf=render
https://pubmed.ncbi.nlm.nih.gov/26195726
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516796/
https://europepmc.org/article/PMC/PMC4516796
https://jem.rupress.org/content/212/8/1283
https://rupress.org/jem/article/212/8/1283/41927/CHMP5-controls-bone-turnover-rates-by-dampening-NF
https://rupress.org/jem/article-pdf/212/8/1283/1163936/jem_20150407.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516796/figure/fig7/

STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons

Συγγραφείς: Kapuralin, Katarina, Ćurlin, Marija, Mitrečić, Dinko, Kosi, Nina, Schwarzer, Christoph, Glavan, Gordana, Gajović, Srećko

Πηγή: Molecular and Cellular Neurosciences

Θεματικοί όροι: Male, 0301 basic medicine, Cytoplasm, brain, neurons, Stam2, Hippocampus, ESCRT, Cellular and Molecular Neuroscience, Mice, 03 medical and health sciences, Cerebellum / metabolism, Cytoplasm / metabolism, Cerebellum, expression, Animals, Olfactory Bulb / metabolism, endosome, Molecular Biology, Cells, Cultured, Adaptor Proteins, Signal Transducing, Cell Nucleus, Neurons, 0303 health sciences, Endosomal Sorting Complexes Required for Transport, Cell Nucleus / metabolism, Neurons / metabolism, nucleus, Cell Biology, Phosphoproteins, Olfactory Bulb, Mice, Inbred C57BL, Protein Transport, Hippocampus / metabolism, Organ Specificity, Phosphoproteins / genetics, Endosomal Sorting Complexes Required for Transport / metabolism, Phosphoproteins / metabolism, Adaptor Proteins, Signal Transducing / genetics, STAM2, Adaptor Proteins, Signal Transducing / metabolism, Endosomal Sorting Complexes Required for Transport / genetics

Περιγραφή αρχείου: text/url; application/pdf

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/26101075
https://core.ac.uk/display/33324206
https://www.sciencedirect.com/science/article/pii/S1044743115000974
https://europepmc.org/article/MED/26101075
https://www.bib.irb.hr/809976
https://pubmed.ncbi.nlm.nih.gov/26101075/
https://repozitorij.uni-lj.si/IzpisGradiva.php?id=83354
https://doi.org/10.1016/j.mcn.2015.06.009
https://hdl.handle.net/20.500.12556/RUL-83354
https://urn.nsk.hr/urn:nbn:hr:105:983995
https://doi.org/10.1016/j.mcn.2015.06.009

Reduction of Glucose Uptake through Inhibition of Hexose Transporters and Enhancement of Their Endocytosis by Methylglyoxal in Saccharomyces cerevisiae

Συγγραφείς: Yoshida, Aya, Wei, Dandan, Nomura, Wataru, Izawa, Shingo, Inoue, Yoshiharu

Συνεισφορές: 井上, 善晴

Πηγή: Journal of Biological Chemistry. 287:701-711

Θεματικοί όροι: 0301 basic medicine, Glucose Transporter Type 1/antagonists & inhibitors, Saccharomyces cerevisiae Proteins, Monosaccharide Transport Proteins, Saccharomyces cerevisiae/cytology, Protein Kinase C/metabolism, TOR Serine-Threonine Kinases/metabolism, Saccharomyces cerevisiae, Ubiquitin-Protein Ligase Complexes/metabolism, Endocytosis/drug effects, Hypoglycemic Agents/pharmacology, 03 medical and health sciences, Saccharomyces cerevisiae/metabolism, Pyruvaldehyde/pharmacology, Rsp5, methylglyoxal, endocytosis, Glucose/metabolism, Animals, Humans, Hypoglycemic Agents, phospholipase C, Monosaccharide Transport Proteins/metabolism, Protein Kinase C, Glucose Transporter Type 1, 0303 health sciences, Glucose Transporter Type 4, Endosomal Sorting Complexes Required for Transport/metabolism, Endosomal Sorting Complexes Required for Transport, Biological Transport/drug effects, TOR Serine-Threonine Kinases, Ubiquitin-Protein Ligase Complexes, Proteolysis/drug effects, Biological Transport, Saccharomyces cerevisiae Proteins/metabolism, Pyruvaldehyde, Monosaccharide Transport Proteins/antagonists & inhibitors, Endocytosis, Rats, 3. Good health, Glucose Transporter Type 4/antagonists & inhibitors, Glucose, hexose transporter, Type C Phospholipases, Proteolysis, Type C Phospholipases/metabolism, Saccharomyces cerevisiae/drug effects

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: http://www.jbc.org/content/287/1/701.full.pdf
https://pubmed.ncbi.nlm.nih.gov/22094464
https://www.scienceopen.com/document?vid=abe39c0f-f169-4cbe-879e-8cdd8f85c22e
http://www.jbc.org/content/287/1/701.full
https://www.sciencedirect.com/science/article/pii/S0021925820535527
https://www.ncbi.nlm.nih.gov/pubmed/22094464
https://www.jbc.org/content/287/1/701.abstract
https://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/169680/1/jbc.M111.322222.pdf

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation

Συγγραφείς: Hayer, Arnold, Stoeber, Miriam, Ritz, Danilo, Engel, Sabrina, Meyer, Hemmo, Helenius, Ari

Πηγή: J Cell Biol
The Journal of Cell Biology, Vol. 191, No 3 (2010) pp. 615-629
The Journal of Cell Biology, 191 (3)
J Cell Biol. 2010 Nov 1;191(3):615-29.

Θεματικοί όροι: Endosomal Sorting Complexes Required for Transport/metabolism, Endosomal Sorting Complexes Required for Transport, Caveolin 1, Medizin, Ubiquitination, Caveolin 1/metabolism, Lysosomes/metabolism, Ubiquitinated Proteins/metabolism, Ubiquitinated Proteins, Cell Line, Humans, Lysosomes, Biologie, Research Articles, HeLa Cells

Περιγραφή αρχείου: application/pdf; application/application/pdf

Σύνδεσμος πρόσβασης: https://europepmc.org/articles/pmc3003328?pdf=render
https://pubmed.ncbi.nlm.nih.gov/21041450
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003328/
http://europepmc.org/articles/PMC3003328
https://archive-ouverte.unige.ch/unige:123108/ATTACHMENT01
https://archive-ouverte.unige.ch/unige:123108
https://rupress.org/jcb/article-pdf/191/3/615/1348682/jcb_201003086.pdf
https://rupress.org/jcb/article/191/3/615/36036/Caveolin-1-is-ubiquitinated-and-targeted-to
https://archive-ouverte.unige.ch/unige:123108
http://hdl.handle.net/20.500.11850/158124

E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN

Συγγραφείς: Jovana Drinjakovic, Laure Strochlic, Hosung Jung, Douglas Simon Campbell, Christine E. Holt, Asha Dwivedy

Συνεισφορές: Jovana Drinjakovic, Hosung Jung, Douglas S. Campbell, Laure Strochlic, Asha Dwivedy, Christine E. Holt, Jung, Ho Sung

Πηγή: Neuron

Θεματικοί όροι: Embryo, Nonmammalian, Xenopus, Nedd4 Ubiquitin Protein Ligases, DEVBIO, Xenopus Proteins, Green Fluorescent Proteins/genetics, Retinal Ganglion Cells/cytology, Tissue Culture Techniques, Growth Cones/physiology, Phosphatidylinositol 3-Kinases, PTEN Phosphohydrolase/metabolism, Axons/physiology, Cell Line, Transformed, Microscopy, Nonmammalian, Microscopy, Confocal, PTEN Phosphohydrolase/genetics, Gene Expression Regulation, Developmental, Down-Regulation/genetics, Endosomal Sorting Complexes Required for Transport/metabolism, Retinal Ganglion Cells/physiology, Confocal/methods, Electroporation, Embryo, SIGNALING, Phosphatidylinositol 3-Kinases/metabolism, Superior Colliculi/cytology, Down-Regulation/physiology, Immunoprecipitation/methods, Genetic/methods, Mutation/genetics, Neuroscience(all), Green Fluorescent Proteins, Growth Cones, Down-Regulation, Electroporation/methods, Arginine, MOLNEURO, Article, Retina, Cell Line, Transduction, Retina/cytology, Animals, Humans, Immunoprecipitation, Ubiquitin-Protein Ligases/genetics, Arginine/genetics, Lysine/genetics, Ubiquitin-Protein Ligases/metabolism, Endosomal Sorting Complexes Required for Transport, Signal Transduction/physiology, Lysine, PTEN Phosphohydrolase, Developmental/physiology, Ubiquitin/genetics, Axons, Developmental/genetics, Transformed, Gene Expression Regulation, Mutation, Signal Transduction/genetics

Περιγραφή αρχείου: 341~357

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/20159448
https://www.sciencedirect.com/science/article/abs/pii/S0896627310000425
https://www.scienceopen.com/document?vid=ade1883f-06ae-4116-9795-4532dba7b7e1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862300/
https://www.sciencedirect.com/science/article/pii/S0896627310000425
http://europepmc.org/articles/PMC2862300
https://core.ac.uk/display/81104585

SHIP2 (SH2 Domain-containing Inositol Phosphatase 2) SH2 Domain Negatively Controls SHIP2 Monoubiquitination in Response to Epidermal Growth Factor

Συγγραφείς: De Schutter, Julie, Guillabert, Aude, Imbault, Virginie, Degraef, Chantal, Erneux, Christophe, Communi, David, Pirson, Isabelle

Πηγή: The Journal of biological chemistry, 284 (52

Θεματικοί όροι: 0301 basic medicine, Protein Structure, Tertiary -- physiology, Proteasome Endopeptidase Complex, Time Factors, Nedd4 Ubiquitin Protein Ligases, Ubiquitin-Protein Ligases, Amino Acid Motifs, Epidermal Growth Factor -- pharmacology, Models, Biological, Cercopithecus aethiops, Ubiquitination -- physiology, Proteasome Endopeptidase Complex -- metabolism, 03 medical and health sciences, Proteasome Endopeptidase Complex -- genetics, Models, Protein Structure, Tertiary -- physiology, Chlorocebus aethiops, Animals, Humans, Proto-Oncogene Proteins c-cbl, Proto-Oncogene Proteins c-cbl -- metabolism, Epidermal Growth Factor -- metabolism, Endosomal Sorting Complexes Required for Transport -- metabolism, Endosomal Sorting Complexes Required for Transport, Epidermal Growth Factor, Ubiquitination -- drug effects, Ubiquitination, Amino Acid Motifs -- physiology, Sciences bio-médicales et agricoles, Phosphoric Monoester Hydrolases -- genetics, Ubiquitin-Protein Ligases -- metabolism, Biological, Phosphoric Monoester Hydrolases, Protein Structure, Tertiary, Proto-Oncogene Proteins c-cbl -- genetics, Endosomal Sorting Complexes Required for Transport -- genetics, Ubiquitin-Protein Ligases -- genetics, Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases, COS Cells, Phosphoric Monoester Hydrolases -- metabolism

Περιγραφή αρχείου: 2 full-text file(s): application/pdf; application/pdf

Σύνδεσμος πρόσβασης: http://www.jbc.org/content/284/52/36062.full.pdf
https://pubmed.ncbi.nlm.nih.gov/19880507
https://www.jbc.org/article/S0021-9258(20)37417-2/fulltext
https://www.ncbi.nlm.nih.gov/pubmed/19880507
https://www.jbc.org/content/284/52/36062.full.pdf
https://www.sciencedirect.com/science/article/pii/S0021925820374172
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/53754/Details
https://europepmc.org/articles/PMC2794722/
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/53754