Development of immunoliposomes with E-Selectin affinity to target endothelial inflammation: direct comparison of antibody types.

Συγγραφείς: Gkartziou F; Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece., Petegnief V; Department of Neuroscience and Experimental Therapeutics, Biomedical Research Institute of Barcelona (IIBB-CSIC), Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain., Kannavou M; Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece., Flavián-Lázaro AC; Department of Neuroscience and Experimental Therapeutics, Biomedical Research Institute of Barcelona (IIBB-CSIC), Barcelona, Spain., Pascual N; Nanobiotechnology for Diagnostics (Nb4D), Department of Chemical and Biomolecular Nanotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain.; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Marquez-Kisinousky L; Department of Neuroscience and Experimental Therapeutics, Biomedical Research Institute of Barcelona (IIBB-CSIC), Barcelona, Spain., Marco P; Nanobiotechnology for Diagnostics (Nb4D), Department of Chemical and Biomolecular Nanotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain.; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Planas AM; Department of Neuroscience and Experimental Therapeutics, Biomedical Research Institute of Barcelona (IIBB-CSIC), Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain., Antimisiaris SG; Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.; Institute of Chemical Engineering Sciences, FORTH/ICE-HT, Patras, Greece.

Πηγή: Journal of liposome research [J Liposome Res] 2026 Sep; Vol. 36 (3), pp. 303-315. Date of Electronic Publication: 2026 Mar 18.

Τύπος έκδοσης: Journal Article; Comparative Study

Στοιχεία περιοδικού: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9001952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2394 (Electronic) Linking ISSN: 08982104 NLM ISO Abbreviation: J Liposome Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/immunology , E-Selectin*/metabolism , Liposomes*/chemistry , Liposomes*/immunology , Antibodies, Monoclonal*/immunology , Antibodies, Monoclonal*/chemistry , Inflammation*/drug therapy , Inflammation*/immunology , Endothelial Cells*/immunology , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects, Polyethylene Glycols/chemistry ; Animals ; Humans

Tocotrienol as a multi-target inhibitor of ICAM-1, VCAM-1, and E-selectin: Comparison using AutoDock and GNINA docking with molecular dynamics simulation.

Συγγραφείς: Abdah HW; Cardiovascular Advancement and Research Excellence Institute (CARE Institute), Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia., Jusoh SA; Department of Life Science, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM) Puncak Alam Selangor Campus, Puncak Alam, Selangor 42300, Malaysia., Dzulkharnien NSF; Cardiovascular Advancement and Research Excellence Institute (CARE Institute), Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia., Hanafi NI; Cardiovascular Advancement and Research Excellence Institute (CARE Institute), Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia., Mohd Nasir AM; Department of Life Science, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM) Puncak Alam Selangor Campus, Puncak Alam, Selangor 42300, Malaysia., Abd Muid S; Cardiovascular Advancement and Research Excellence Institute (CARE Institute), Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia., Mohd Kasim NA; Cardiovascular Advancement and Research Excellence Institute (CARE Institute), Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia; Department of Pathology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) Sungai Buloh Selangor Campus, Sungai Buloh, Selangor 47000, Malaysia. Electronic address: noor202@uitm.edu.my.

Πηγή: Computational biology and chemistry [Comput Biol Chem] 2026 Oct; Vol. 124 (Pt 1), pp. 109136. Date of Electronic Publication: 2026 May 27.

Τύπος έκδοσης: Journal Article; Comparative Study

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Intercellular Adhesion Molecule-1*/metabolism , Intercellular Adhesion Molecule-1*/chemistry , Tocotrienols*/chemistry , Tocotrienols*/pharmacology , E-Selectin*/antagonists & inhibitors , E-Selectin*/metabolism , E-Selectin*/chemistry , Vascular Cell Adhesion Molecule-1*/antagonists & inhibitors , Vascular Cell Adhesion Molecule-1*/metabolism , Vascular Cell Adhesion Molecule-1*/chemistry , Molecular Dynamics Simulation* , Molecular Docking Simulation*, Humans

Inflammation-Inducible Expression of Human Indoleamine 2,3-Dioxygenase Driven by the E-Selectin Promoter Ameliorates Collagen-Induced Arthritis.

Συγγραφείς: Karaçay M; Department of Medicine-Immunology, Institute of Health Sciences, Bursa Uludag University, Bursa, Türkiye.; Division of Medical Genetics, Department of Internal Medicine, Faculty of Medicine, Van Yuzuncu Yil University, Van, Türkiye., Yılmaz İ; Department of Medicine-Immunology, Institute of Health Sciences, Bursa Uludag University, Bursa, Türkiye., Barazi Soydaş AÖ; Department of Immunology, Graduate School of Health Sciences, Gazi University, Ankara, Türkiye., Güvenç-Bayram G; Department of Physiology, Faculty of Veterinary Medicine, Dokuz Eylul University, Izmir, Türkiye., Ersoy F; Department of Molecular Biology and Genetics, Bursa Uludag University, Bursa, Türkiye., Özgüden Akkoç CG; Department of Histology and Embryology, Faculty of Veterinary Medicine, Bursa Uludag University, Bursa, Türkiye., Yılmaztepe Oral A; Department of Medical Biochemistry, Faculty of Medicine, Bursa Uludag University, Bursa, Türkiye., Akkoç A; Department of Pathology, Faculty of Veterinary Medicine, Bursa Uludag University, Bursa, Türkiye., Yalçın M; Department of Physiology, Faculty of Veterinary Medicine, Bursa Uludag University, Bursa, Türkiye., Oral HB; Department of Immunology, Faculty of Medicine, Bursa Uludag University, Bursa, Türkiye.

Πηγή: Human gene therapy [Hum Gene Ther] 2026 Sep; Vol. 37 (17-18), pp. 833-848. Date of Electronic Publication: 2026 Jun 04.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Indoleamine-Pyrrole 2,3,-Dioxygenase*/genetics , Indoleamine-Pyrrole 2,3,-Dioxygenase*/metabolism , Arthritis, Experimental*/therapy , Arthritis, Experimental*/genetics , Arthritis, Experimental*/pathology , E-Selectin*/genetics , Inflammation*/genetics , Promoter Regions, Genetic* , Genetic Therapy*, Interleukin-1beta/metabolism ; Antigens, CD/genetics ; Antigens, CD/metabolism ; CD4-Positive T-Lymphocytes/immunology ; Antigens, Differentiation, Myelomonocytic/genetics ; Antigens, Differentiation, Myelomonocytic/metabolism ; Animals ; Humans ; Mice ; HeLa Cells ; Disease Models, Animal ; Mice, Inbred BALB C ; Gene Therapy Agents

Linking cytokine signaling to vascular response: Impedance biosensing of E-selectin and IL-6 for endothelial activation assessment.

Συγγραφείς: David BE; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX, 75248, USA., Madhurantakam S; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX, 75248, USA., Mathew G; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX, 75248, USA., Desai AM; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX, 75248, USA., Karnam JB; EnLiSense LLC, Allen, TX, 75013, USA., Dhamu VN; EnLiSense LLC, Allen, TX, 75013, USA., Muthukumar S; EnLiSense LLC, Allen, TX, 75013, USA., Prasad S; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX, 75248, USA. Electronic address: Shalini.Prasad@UTDallas.edu.

Πηγή: Biosensors & bioelectronics [Biosens Bioelectron] 2027 Jan 01; Vol. 315, pp. 119230. Date of Electronic Publication: 2026 Sep 17.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/blood , Interleukin-6*/blood , Dielectric Spectroscopy*/instrumentation , Dielectric Spectroscopy*/methods , Biosensing Techniques*/instrumentation, Gold/chemistry ; Biomarkers/blood ; Humans ; Equipment Design ; Limit of Detection

Clinical significance of soluble E-selectin and soluble vascular cell adhesion molecule-1 levels in umbilical cord blood for neonatal respiratory distress syndrome: a retrospective study.

Συγγραφείς: Huang Q; Department of General Pediatrics, Taizhou People's Hospital Affiliated to Nanjing Medical University, Taizhou City, Jiangsu Province, China., Qin Y; Department of General Pediatrics, Taizhou People's Hospital Affiliated to Nanjing Medical University, Taizhou City, Jiangsu Province, China.

Πηγή: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2026 Dec; Vol. 39 (1), pp. 2660017. Date of Electronic Publication: 2026 May 10.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101136916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4954 (Electronic) Linking ISSN: 14764954 NLM ISO Abbreviation: J Matern Fetal Neonatal Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/blood , Respiratory Distress Syndrome, Newborn*/blood , Respiratory Distress Syndrome, Newborn*/diagnosis , Vascular Cell Adhesion Molecule-1*/blood , Fetal Blood*/chemistry , Fetal Blood*/metabolism, Biomarkers/blood ; Infant, Premature/blood ; Humans ; Retrospective Studies ; Infant, Newborn ; Female ; Male ; Prognosis ; Apgar Score ; ROC Curve

Pathophysiological mechanisms and therapeutic potential of E-selectin in pulmonary arterial hypertension.

Συγγραφείς: Lama E; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Wang Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Wu J; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Ma Q; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Chen H; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Wang Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Yang Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China.; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China., Liu C; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Ni X; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China., Zhou Z; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Biological Targeted Therapy, Huazhong University of Science and Technology, Ministry of Education, Wuhan, Hubei, China.

Πηγή: Frontiers in immunology [Front Immunol] 2026 Jul 10; Vol. 17, pp. 1754940. Date of Electronic Publication: 2026 Jul 10 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/metabolism , E-Selectin*/genetics , Pulmonary Arterial Hypertension*/drug therapy , Pulmonary Arterial Hypertension*/metabolism , Pulmonary Arterial Hypertension*/physiopathology, Humans ; Animals ; Vascular Remodeling ; Biomarkers ; Pulmonary Artery

Association of E-Selectin with Inflammation, Mineral and Bone Disorder, and Endothelial Dysfunction in Hemodialysis Patients.

Συγγραφείς: Rusu CC; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Moldovan D; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Potra A; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Tirinescu D; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Ticala M; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Maslyennikov Y; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Urs A; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania., Pop RM; Discipline of Pharmacology, Toxicology and Clinical Pharmacology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania., Ticolea M; Discipline of Pathophysiology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania., Bondor CI; Discipline of Medical Informatics and Biostatistics, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 6 Pasteur Street, 400349 Cluj-Napoca, Romania., Kacso I; Discipline of Nephrology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.; Department of Nephrology, County Emergency Clinical Hospital Cluj, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2026 Jun 06; Vol. 27 (12). Date of Electronic Publication: 2026 Jun 06.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/blood , E-Selectin*/metabolism , Renal Dialysis*/adverse effects , Inflammation*/metabolism , Inflammation*/blood , Endothelium, Vascular*/metabolism , Endothelium, Vascular*/physiopathology , Bone Diseases*/metabolism , Bone Diseases*/etiology, Biomarkers/blood ; Antigens, CD/blood ; Parathyroid Hormone/blood ; Receptors, Cell Surface/blood ; Humans ; Middle Aged ; Female ; Male ; Aged ; Cross-Sectional Studies

Proteomic analysis of extracellular vesicles released from endothelial cells in vitro reveals increased levels of E-selectin and dual specificity phosphatase 7 as a potential marker of TNFα-mediated apoptosis.

Συγγραφείς: Collier MEW; Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, United Kingdom., Cao TH; Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, United Kingdom.; Leicester van Geest Multi-OMICS facility, University of Leicester, Leicester, United Kingdom., Quinn PA; Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; Leicester van Geest Multi-OMICS facility, University of Leicester, Leicester, United Kingdom., Sandhu JK; Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; Leicester van Geest Multi-OMICS facility, University of Leicester, Leicester, United Kingdom., Jones DJL; Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, United Kingdom.; Leicester van Geest Multi-OMICS facility, University of Leicester, Leicester, United Kingdom.; Leicester Cancer Research Centre, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, University of Leicester, Leicester, United Kingdom., Goodall AH; Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, United Kingdom.

Πηγή: PloS one [PLoS One] 2026 Jun 26; Vol. 21 (6), pp. e0352394. Date of Electronic Publication: 2026 Jun 26 (Print Publication: 2026).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Tumor Necrosis Factor-alpha*/pharmacology , Tumor Necrosis Factor-alpha*/metabolism , Apoptosis*/drug effects , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Human Umbilical Vein Endothelial Cells*/drug effects , E-Selectin*/metabolism , Proteomics*/methods , Protein Tyrosine Phosphatases*/metabolism, Biomarkers/metabolism ; Lipoproteins, LDL/pharmacology ; Proteome/metabolism ; Endothelial Cells/metabolism ; Caspase 7/metabolism ; Humans ; Tandem Mass Spectrometry

Canonical human blood dendritic cells are distinguished by robust E-selectin binding.

Συγγραφείς: Ales E; Department of Translational Medicine and Translational Glycobiology Institute, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States., Sackstein R; Department of Translational Medicine and Translational Glycobiology Institute, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States.

Πηγή: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2026 Feb 09; Vol. 215 (2).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Association of Immunologists Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/metabolism , E-Selectin*/immunology , Dendritic Cells*/immunology , Dendritic Cells*/metabolism, Sialyl Lewis X Antigen/metabolism ; Humans ; Protein Binding

E-selectin-targeted microbubbles combined with ultrasound improves renoprotective effects of methylprednisolone on cisplatin-induced acute kidney injury in rats.

Συγγραφείς: Si R; Department of Ophthalmology, Second Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, 710004, People's Republic of China., Mo L; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, People's Republic of China., Zhao C; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, People's Republic of China., Xu Z; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, People's Republic of China., Zhao W; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, People's Republic of China., Wu J; Department of Pathology, School of Basic Medicine and Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, People's Republic of China., Fu R; Department of Nephrology, Second Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, 710004, People's Republic of China. pipifu@126.com.; Nephrology & Critical Care Medicine of Xi'an International Science and Technology Cooperation Base, Xi'an, 710004, People's Republic of China. pipifu@126.com., Ren S; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, People's Republic of China. rst@mail.xjtu.edu.cn.; Department of Nephrology, Second Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, 710004, People's Republic of China. rst@mail.xjtu.edu.cn.

Πηγή: Scientific reports [Sci Rep] 2026 Apr 11; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 11.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Microbubbles*/therapeutic use , E-Selectin*/metabolism , Acute Kidney Injury*/chemically induced , Acute Kidney Injury*/metabolism , Acute Kidney Injury*/drug therapy , Acute Kidney Injury*/pathology , Acute Kidney Injury*/therapy , Cisplatin*/adverse effects , Methylprednisolone*/pharmacology , Methylprednisolone*/administration & dosage, Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Drug Delivery Systems/methods ; Anti-Inflammatory Agents/pharmacology ; Animals ; Rats ; Male ; Rats, Sprague-Dawley ; Disease Models, Animal

E-selectin targeting cascaded ultrasonic cavitation enables liposomes to deeply penetrate pancreatic cancer.

Συγγραφείς: Hu C; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China., Chen J; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China., Liu X; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China., Zhao Y; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China., Pan H; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China., Fang X; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China., Yin H; Department of Ultrasonic Diagnostic Center, Ningbo No. 2 Hospital, Ningbo, 315010, PR China., Wang G; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China. Electronic address: wangguowei@zju.edu.cn., Huang P; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, PR China. Electronic address: huangpintong@zju.edu.cn.

Πηγή: Cancer letters [Cancer Lett] 2026 Feb 28; Vol. 639, pp. 218129. Date of Electronic Publication: 2025 Nov 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , E-Selectin*/metabolism , Deoxycytidine*/analogs & derivatives , Deoxycytidine*/administration & dosage , Deoxycytidine*/pharmacology , Deoxycytidine*/pharmacokinetics , Deoxycytidine*/chemistry , Drug Delivery Systems*/methods , Liposomes*, Fluorocarbons/chemistry ; Fluorocarbons/administration & dosage ; Prodrugs/administration & dosage ; Humans ; Animals ; Gemcitabine ; Cell Line, Tumor ; Mice ; Xenograft Model Antitumor Assays ; Pentanes

[Force-regulation mechanism of E-selectin mediated adhesion and activation of MDA-MB-231 cells under fluid shear stress].

Συγγραφείς: Zhong P; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, P. R. China., Fang Y; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, P. R. China., Wu J; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, P. R. China.

Πηγή: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi [Sheng Wu Yi Xue Gong Cheng Xue Za Zhi] 2026 Feb 25; Vol. 43 (1), pp. 97-105.

Τύπος έκδοσης: English Abstract; Journal Article

Στοιχεία περιοδικού: Publisher: Sichuan Sheng sheng wu yi xue gong cheng xue hui Country of Publication: China NLM ID: 9426398 Publication Model: Print Cited Medium: Print ISSN: 1001-5515 (Print) Linking ISSN: 10015515 NLM ISO Abbreviation: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cell Adhesion*/physiology , E-Selectin*/metabolism , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Stress, Mechanical*, Integrin alpha5beta1/metabolism ; Calcium/metabolism ; Fibronectins/metabolism ; Hyaluronan Receptors/metabolism ; Humans ; MDA-MB-231 Cells ; Female ; Shear Strength

Adhesion molecules in the maternal-fetal interface in healthy pregnancies and preeclampsia.

Συγγραφείς: Frisch IK; Division of Obstetrics and Gynecology, Department of Obstetrics, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Michelsen TM; Division of Obstetrics and Gynecology, Department of Obstetrics, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Lekva T; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Roland MCP; Division of Obstetrics and Gynecology, Department of Obstetrics, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Department of Medical Biochemistry, Oslo University Hospital Rikshospitalet, Oslo, Norway., Westerberg AC; Division of Obstetrics and Gynecology, Department of Obstetrics, Oslo University Hospital Rikshospitalet, Oslo, Norway.; School of Health Sciences, Kristiania University College, Oslo, Norway.

Πηγή: Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 2026 Feb; Vol. 105 (2), pp. 298-308. Date of Electronic Publication: 2025 Dec 12.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Wiley Country of Publication: United States NLM ID: 0370343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0412 (Electronic) Linking ISSN: 00016349 NLM ISO Abbreviation: Acta Obstet Gynecol Scand Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Pre-Eclampsia*/blood , Vascular Cell Adhesion Molecule-1*/blood , Intercellular Adhesion Molecule-1*/blood , E-Selectin*/blood , Placenta*/metabolism , Placenta*/blood supply , Cell Adhesion Molecules*/blood, Biomarkers/blood ; Humans ; Female ; Pregnancy ; Adult ; Case-Control Studies ; Longitudinal Studies

Therapeutic potential of endothelial progenitor cell-derived exosomal miRNA-31 in alleviating septic peritonitis via E-selectin inhibition.

Συγγραφείς: Liu S; Department of Emergency, Gansu Provincial Hospital, Lanzhou, Gansu Province, China., Wang B; The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China., Zhang M; The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China., Ma G; The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China.

Πηγή: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2026 Jan 21; Vol. 215 (1).

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: American Association of Immunologists Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): MicroRNAs*/genetics , MicroRNAs*/metabolism , MicroRNAs*/blood , Peritonitis*/therapy , Peritonitis*/immunology , Sepsis*/immunology , Sepsis*/therapy , Endothelial Progenitor Cells*/metabolism , Exosomes*/metabolism , Exosomes*/genetics , E-Selectin*/antagonists & inhibitors , E-Selectin*/metabolism, Animals ; Humans ; Mice ; Male ; Female ; Disease Models, Animal ; Apoptosis ; Middle Aged ; Mice, Inbred C57BL ; Cell Proliferation ; Aged

CD44 enhances E-selectin-PSGL-1 interaction by binding to distinct sites on E-selectin.

Συγγραφείς: Ding Q; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China., Wu Y; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Forensic Science and Technology, Criminal Investigation Police University of China, Shenyang, 110854, China., Li L; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; Key Laboratory of Biorheology Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China., Zhang X; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China., Zheng Z; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China., Zhang M; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China., Zhang Y; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China., Long M; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: mlong@imech.ac.cn., Lü S; Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity, and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: lsq@imech.ac.cn.

Πηγή: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 333 (Pt 1), pp. 148825. Date of Electronic Publication: 2025 Nov 05.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hyaluronan Receptors*/metabolism , Hyaluronan Receptors*/chemistry , E-Selectin*/metabolism , E-Selectin*/chemistry , Membrane Glycoproteins*/metabolism , Membrane Glycoproteins*/chemistry, Humans ; Protein Binding ; Binding Sites ; Cell Adhesion ; Molecular Dynamics Simulation ; Ligands

Fucosylation enhances CD34⁺ hematopoietic stem cell homing and longevity via E-selectin-mediated adhesion and signaling.

Συγγραφείς: Al-Amoodi AS; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Alghuneim AA; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.; Current Address: Research and Innovation, King Faisal Specialist Hospital & Research Centre, Riyadh, 11211, Kingdom of Saudi Arabia., Malki JS; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Nozue S; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Li Y; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Kai J; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Zhang H; Analytical Chemistry Core Lab - Proteomics Unit, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Bensaddek D; Analytical Chemistry Core Lab - Proteomics Unit, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Abdel-Aziz AK; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.; Current Address: Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt., Habuchi S; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia., Merzaban JS; Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia. jasmeen.merzaban@kaust.edu.sa.

Πηγή: BMC cancer [BMC Cancer] 2026 Jan 29; Vol. 26 (1). Date of Electronic Publication: 2026 Jan 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

Ιατρικοί όροι (MeSH): E-Selectin*/metabolism , Fucose*/metabolism , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , Antigens, CD34*/metabolism, Fucosyltransferases/metabolism ; Fucosyltransferases/genetics ; Humans ; Animals ; Signal Transduction ; Mice ; Cell Adhesion ; Cell Movement ; Hematopoietic Stem Cell Transplantation ; Mice, SCID ; Glycosylation

Selectin E upregulation upon forkhead box P1 loss augments neutrophil infiltration and brain damage in hypertensive intracerebral hemorrhage.

Συγγραφείς: Wang N; Department 2 of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan 056000 Hebei, PR China., Wu J; Department 2 of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan 056000 Hebei, PR China., Song Z; Department 2 of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan 056000 Hebei, PR China., Wang H; Department 2 of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan 056000 Hebei, PR China., Zhao Y; Department 1 of Respiratory and Critical Care Medicine, Affiliated Hospital of Hebei University of Engineering, Handan 056000 Hebei, PR China. Electronic address: zhaoyan9261@163.com.

Πηγή: Brain research [Brain Res] 2025 Nov 01; Vol. 1866, pp. 149901. Date of Electronic Publication: 2025 Aug 26.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Forkhead Transcription Factors*/metabolism , Forkhead Transcription Factors*/genetics , Neutrophil Infiltration*/physiology , Intracranial Hemorrhage, Hypertensive*/metabolism , Intracranial Hemorrhage, Hypertensive*/pathology , E-Selectin*/metabolism , E-Selectin*/genetics , Repressor Proteins*/metabolism , Repressor Proteins*/genetics , Brain Injuries*/metabolism, Blood-Brain Barrier/metabolism ; Endothelial Cells/metabolism ; Brain/metabolism ; Brain/pathology ; Neutrophils/metabolism ; Animals ; Mice ; Male ; Up-Regulation ; Humans ; Mice, Inbred C57BL ; Disease Models, Animal

Restricted human CD45 isoglycoforms serve as functional E-selectin ligands and delineate hematopoietic maturity.

Συγγραφείς: Ales E; Department of Translational Medicine and Translational Glycobiology Institute, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, USA., Sackstein R; Department of Translational Medicine and Translational Glycobiology Institute, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, USA. Electronic address: sackstein@fiu.edu.

Πηγή: The Journal of biological chemistry [J Biol Chem] 2025 Aug; Vol. 301 (8), pp. 110431. Date of Electronic Publication: 2025 Jul 01.

Τύπος έκδοσης: Journal Article; Research Support, N.I.H., Extramural

Στοιχεία περιοδικού: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Leukocyte Common Antigens*/metabolism , Leukocyte Common Antigens*/genetics , Leukocyte Common Antigens*/chemistry , Leukemia, Myeloid, Acute*/metabolism , Leukemia, Myeloid, Acute*/pathology , Leukemia, Myeloid, Acute*/genetics , E-Selectin*/metabolism , E-Selectin*/genetics , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , Hematopoietic Stem Cells*/pathology, Protein Isoforms/metabolism ; Protein Isoforms/genetics ; Humans ; Ligands

Dual-Peptide PAMAM Dendrimer Conjugates for Enhanced Cell Uptake via E-Selectin Targeting.

Συγγραφείς: Marrugo KP; Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Concepción 4030000, Chile., Manzo-Merino J; Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Mexico., Jiménez VA; Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Autopista Concepción-Talcahuano 7100, Talcahuano 4260000, Chile., Campos CH; Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Autopista Concepción-Talcahuano 7100, Talcahuano 4260000, Chile., Alderete JB; Instituto de Química de Recursos Naturales (IQRN), Universidad de Talca, Avenida Lircay S/N, Casilla 747, Talca 3460000, Chile.

Πηγή: Bioconjugate chemistry [Bioconjug Chem] 2025 Dec 17; Vol. 36 (12), pp. 2608-2617. Date of Electronic Publication: 2025 Nov 21.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Dendrimers*/chemistry , Dendrimers*/metabolism , E-Selectin*/metabolism , Peptides*/chemistry , Peptides*/metabolism , Drug Carriers*/chemistry , Drug Carriers*/metabolism, Doxorubicin/pharmacology ; Humans ; Human Umbilical Vein Endothelial Cells ; Cell Line, Tumor

Vasculoprotective role of del Nido cardioplegia in open-heart surgery via modulation of E-Selectin, Endocan, and TNF-alpha coronary sinus blood samples.

Συγγραφείς: Kızılyel F; Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. fkizilyel@gmail.com., Cebe T; Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey., Rum M; Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey., Bozali K; Department of Biochemistry, Hamidiye Faculty of Medicine, University of Health Sciences, Istanbul, Turkey., Turgut Ş; Department of Medical Biochemistry, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey., Yılmaz M; Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey., Kehlibar T; Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey., Ketenci B; Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

Πηγή: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2025 Nov 28; Vol. 21 (1), pp. 30. Date of Electronic Publication: 2025 Nov 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090 (Electronic) Linking ISSN: 17498090 NLM ISO Abbreviation: J Cardiothorac Surg Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Heart Arrest, Induced*/methods , Coronary Artery Bypass*/methods , Tumor Necrosis Factor-alpha*/blood , E-Selectin*/blood , Proteoglycans*/blood , Coronary Sinus*/metabolism , Neoplasm Proteins*/blood , Heart Valve Prosthesis Implantation*/methods, Biomarkers/blood ; Aortic Valve Stenosis/surgery ; Humans ; Male ; Female ; Aged ; Middle Aged ; Endothelium, Vascular