Dual-locked targeted alpha-emitter enhanced tumor immunotherapy via Diels-Alder reaction-based self-immolative molecular cage strategy.

Συγγραφείς: Yang MD; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China.; Institute of Nuclear Medicine, Tongji University School of Medicine, Shanghai, 200072, China., Fang K; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China.; College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China., Zhang XY; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China.; Institute of Nuclear Medicine, Tongji University School of Medicine, Shanghai, 200072, China., Yang G; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China.; Institute of Nuclear Medicine, Tongji University School of Medicine, Shanghai, 200072, China., Yi HQ; Department of Nuclear Medicine, Zhejiang Cancer Hospital, Hangzhou, 310022, China., Cai L; Department of Nuclear Medicine, Zhejiang Cancer Hospital, Hangzhou, 310022, China., Qin SS; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China.; Institute of Nuclear Medicine, Tongji University School of Medicine, Shanghai, 200072, China., Yang XD; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China., Rong R; College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China., Shi S; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China. shishuo@tongji.edu.cn., Yu F; Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, School of Chemical Science and Engineering, Shanghai, 200072, China. 0910110013yufei@tongji.edu.cn.; Institute of Nuclear Medicine, Tongji University School of Medicine, Shanghai, 200072, China. 0910110013yufei@tongji.edu.cn.

Πηγή: Military Medical Research [Mil Med Res] 2025 Dec 01; Vol. 12 (1), pp. 84. Date of Electronic Publication: 2025 Dec 01.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: BioMed Central Country of Publication: England NLM ID: 101643181 Publication Model: Electronic Cited Medium: Internet ISSN: 2054-9369 (Electronic) Linking ISSN: 20549369 NLM ISO Abbreviation: Mil Med Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Immunotherapy*/methods , Immunotherapy*/standards , Cycloaddition Reaction*/methods , Neoplasms*/therapy , Alpha Particles*/therapeutic use, Mice ; Animals ; Humans ; Radium/therapeutic use ; Radium/pharmacology ; Cell Line, Tumor

Pretargeted nuclear imaging and radioimmunotherapy based on the inverse electron-demand Diels-Alder reaction.

Συγγραφείς: Zhu Y; Department of Nuclear Medicine, the Second Affiliated Hospital of Soochow University, Suzhou City, China., Jiang J, Ni K, You J, Liu Z, Hong Z

Πηγή: Nuclear medicine communications [Nucl Med Commun] 2025 Dec 01; Vol. 46 (12), pp. 1119-1130. Date of Electronic Publication: 2025 Aug 21.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8201017 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5628 (Electronic) Linking ISSN: 01433636 NLM ISO Abbreviation: Nucl Med Commun Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Radioimmunotherapy*/methods , Cycloaddition Reaction*/methods , Electrons*, Humans ; Animals ; Click Chemistry

Synthesis of xanthenone fused spiro pyrrolidine oxindoles via multicomponent [3 + 2] cycloaddition reactions.

Συγγραφείς: Paramasivam G; Department of Chemistry, College of Engineering, Anna University, Guindy, Chennai, 600025, India., Palanichamy B; Department of Chemistry, College of Engineering, Anna University, Guindy, Chennai, 600025, India., Paramathevar N; Department of Chemistry, College of Engineering, Anna University, Guindy, Chennai, 600025, India. nagaiitd@gmail.com.

Πηγή: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6533-6542. Date of Electronic Publication: 2025 Mar 21.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction* , Oxindoles*/chemical synthesis , Oxindoles*/chemistry , Spiro Compounds*/chemistry , Spiro Compounds*/chemical synthesis , Pyrrolidines*/chemistry , Pyrrolidines*/chemical synthesis, Stereoisomerism ; Molecular Structure ; Models, Molecular ; Crystallography, X-Ray ; Azo Compounds ; Thiosemicarbazones

Recent progress of [5 + 2] cycloaddition reactions in natural product synthesis.

Συγγραφείς: Wang N; State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China. dengjun@nankai.edu.cn., Bai Y; State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China. dengjun@nankai.edu.cn., Zeng Q; State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China. dengjun@nankai.edu.cn., Zhang T; State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China. dengjun@nankai.edu.cn., Deng J; State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China. dengjun@nankai.edu.cn.

Πηγή: Natural product reports [Nat Prod Rep] 2025 Nov 12; Vol. 42 (11), pp. 1755-1785. Date of Electronic Publication: 2025 Nov 12.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 8502408 Publication Model: Electronic Cited Medium: Internet ISSN: 1460-4752 (Electronic) Linking ISSN: 02650568 NLM ISO Abbreviation: Nat Prod Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Biological Products*/chemical synthesis , Biological Products*/chemistry , Cycloaddition Reaction*/methods, Molecular Structure ; Stereoisomerism ; Cyclization

Tracker Nanocatalyst for Screening of Intracellular Copper-Catalyzed Azide-Alkyne Cycloadditions.

Συγγραφείς: Rodríguez-Segura M; Department of Medicinal and Organic Chemistry, Excellence Research Unit of Chemistry Applied to Biomedicine and the Environment, School of Pharmacy, University of Granada, Campus Cartuja s/n, Granada, 18071, Spain.; GENYO, Centre for Genomics and Oncological Research, Pfizer, University of Granada, Andalusian Regional Government, PTS Granada, Avenida de la Ilustración, 114, Granada, 18016, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, 18012, Spain., López-Delgado FJ; DESTINA Genómica S.L, PTS Granada, Avenida de la Innovación 1, Edificio BIC, Armilla, 18100, Spain., Cano-Cortés MV; Department of Medicinal and Organic Chemistry, Excellence Research Unit of Chemistry Applied to Biomedicine and the Environment, School of Pharmacy, University of Granada, Campus Cartuja s/n, Granada, 18071, Spain.; GENYO, Centre for Genomics and Oncological Research, Pfizer, University of Granada, Andalusian Regional Government, PTS Granada, Avenida de la Ilustración, 114, Granada, 18016, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, 18012, Spain., Delgado-González A; Department of Medicinal and Organic Chemistry, Excellence Research Unit of Chemistry Applied to Biomedicine and the Environment, School of Pharmacy, University of Granada, Campus Cartuja s/n, Granada, 18071, Spain.; GENYO, Centre for Genomics and Oncological Research, Pfizer, University of Granada, Andalusian Regional Government, PTS Granada, Avenida de la Ilustración, 114, Granada, 18016, Spain., Diaz-Mochon JJ; Department of Medicinal and Organic Chemistry, Excellence Research Unit of Chemistry Applied to Biomedicine and the Environment, School of Pharmacy, University of Granada, Campus Cartuja s/n, Granada, 18071, Spain.; GENYO, Centre for Genomics and Oncological Research, Pfizer, University of Granada, Andalusian Regional Government, PTS Granada, Avenida de la Ilustración, 114, Granada, 18016, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, 18012, Spain., Sanchez-Martin RM; Department of Medicinal and Organic Chemistry, Excellence Research Unit of Chemistry Applied to Biomedicine and the Environment, School of Pharmacy, University of Granada, Campus Cartuja s/n, Granada, 18071, Spain.; GENYO, Centre for Genomics and Oncological Research, Pfizer, University of Granada, Andalusian Regional Government, PTS Granada, Avenida de la Ilustración, 114, Granada, 18016, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, 18012, Spain.

Πηγή: Small (Weinheim an der Bergstrasse, Germany) [Small] 2025 Oct; Vol. 21 (43), pp. e06185. Date of Electronic Publication: 2025 Sep 16.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101235338 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-6829 (Electronic) Linking ISSN: 16136810 NLM ISO Abbreviation: Small Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Copper*/chemistry , Azides*/chemistry , Alkynes*/chemistry , Cycloaddition Reaction*/methods , Nanoparticles*/chemistry, Catalysis ; Humans

On the Question of the Regio-Orientation, Stereo-Orientation and Molecular Mechanism in the Cascade Cycloaddition/Rearrangement/Elimination Processes Leading to Nitro-Substituted Thiopyran Analogs: DFT Computational Study.

Συγγραφείς: Sadowski M; Cracow University of Technology, CUT Doctoral School, Faculty of Chemical Engineering and Technology, Warszawska 24, 31-155 Cracow, Poland., Dresler E; Łukasiewicz Research Network-Institute of Heavy Organic Synthesis 'Blachownia', Energetyków 9, 47-225 Kędzierzyn-Koźle, Poland., Jasiński R; Cracow University of Technology, Department of Organic Chemistry and Technology, Warszawska 24, 31-155 Cracow, Poland.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 14; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 14.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction*, Density Functional Theory ; Stereoisomerism ; Catalysis

1,3-Dipolar Cycloaddition of Nitrile Imines and Nitrile Oxides to Exocyclic C=N Bonds-An Approach to Spiro -N-Heterocycles.

Συγγραφείς: Petrova JV; Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1-3, 119991 Moscow, Russia.; Organic Chemistry Department, RUDN University, Miklukho-Maklaya St. 6, 117198 Moscow, Russia., Kukushkin ME; Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1-3, 119991 Moscow, Russia., Beloglazkina EK; Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1-3, 119991 Moscow, Russia.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 05; Vol. 26 (17). Date of Electronic Publication: 2025 Sep 05.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Nitriles*/chemistry , Cycloaddition Reaction*/methods , Imines*/chemistry , Oxides*/chemistry , Spiro Compounds*/chemistry , Spiro Compounds*/chemical synthesis , Heterocyclic Compounds*/chemistry , Heterocyclic Compounds*/chemical synthesis, Carbon/chemistry

Intramolecular cycloaddition of nitrones in total synthesis of natural products.

Συγγραφείς: Yokoshima S; Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya 464-8601, Japan. yokoshima.satoshi.v7@f.mail.nagoya-u.ac.jp.

Πηγή: Natural product reports [Nat Prod Rep] 2025 Jul 16; Vol. 42 (7), pp. 1071-1090. Date of Electronic Publication: 2025 Jul 16.

Τύπος έκδοσης: Journal Article; Review; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 8502408 Publication Model: Electronic Cited Medium: Internet ISSN: 1460-4752 (Electronic) Linking ISSN: 02650568 NLM ISO Abbreviation: Nat Prod Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Nitrogen Oxides*/chemistry , Biological Products*/chemical synthesis , Biological Products*/chemistry , Cycloaddition Reaction*/methods, Molecular Structure ; Alkenes/chemistry

Overcoming the Reversibility in the Diels-Alder Reaction of Bio-Based Electron-Poor Furans with Maleimides Through Liquid-to-Solid Phase Transition.

Συγγραφείς: Galkin KI; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt, 47, 119991 Moscow, Russia.; Center for Project Activities, Moscow Polytechnic University (Moscow Polytech), Bolshaya Semyonovskaya Str., 38, 107023 Moscow, Russia., Zakharova DV; NTI Center 'Digital Materials Science: New Materials and Substances', Bauman Moscow State Technical University, 2nd Baumanskaya Str., 5, 105005 Moscow, Russia.; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova Str., 28, bld. 1., 119991 Moscow, Russia., Aysin RR; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova Str., 28, bld. 1., 119991 Moscow, Russia., Danshina AA; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova Str., 28, bld. 1., 119991 Moscow, Russia., Pak AM; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova Str., 28, bld. 1., 119991 Moscow, Russia., Sandulenko IV; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova Str., 28, bld. 1., 119991 Moscow, Russia., Novikov RA; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt, 47, 119991 Moscow, Russia., Egorova KS; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt, 47, 119991 Moscow, Russia.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 08; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 08.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Furans*/chemistry , Cycloaddition Reaction*/methods , Maleimides*/chemistry , Phase Transition*, Electrons ; Stereoisomerism ; Thermodynamics ; Kinetics

Cycloadditions as a Sweet Route to 'Double C -Glycosylation'.

Συγγραφείς: Mahoney KPP; School of Chemistry, Integrated Institute of Engineering, and BSRC, University of St. Andrews, St. Andrews KY16 9ST, UK.; TopChem Pharmaceuticals, Ballymote Business Park, Carrownanty, F56 RX08 Ballymote, Ireland.; School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich NR4 7TJ, UK., Lynch R; School of Chemistry, Integrated Institute of Engineering, and BSRC, University of St. Andrews, St. Andrews KY16 9ST, UK., Bown RT; School of Chemistry, Integrated Institute of Engineering, and BSRC, University of St. Andrews, St. Andrews KY16 9ST, UK., Sharma SV; School of Chemistry, Integrated Institute of Engineering, and BSRC, University of St. Andrews, St. Andrews KY16 9ST, UK., Chueakwon P; School of Chemistry, Integrated Institute of Engineering, and BSRC, University of St. Andrews, St. Andrews KY16 9ST, UK., Stephenson GR; School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich NR4 7TJ, UK., Cordes DB; School of Chemistry, University of St. Andrews, St. Andrews KY16 9ST, UK., Slawin AMZ; School of Chemistry, University of St. Andrews, St. Andrews KY16 9ST, UK., Goss RJM; School of Chemistry, Integrated Institute of Engineering, and BSRC, University of St. Andrews, St. Andrews KY16 9ST, UK.

Πηγή: Biomolecules [Biomolecules] 2025 Jun 19; Vol. 15 (6). Date of Electronic Publication: 2025 Jun 19.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction*, Glycosylation ; Glycosides/chemistry

Decarboxylative click cycloaddition: an emerging strategy towards substituted 1,2,3-triazole derivatives.

Συγγραφείς: Kaur M; Laboratory of Organic Synthesis and Catalysis, Department of Chemistry, Central University of Punjab, Bathinda, 151401, India., Bharti D; Laboratory of Organic Synthesis and Catalysis, Department of Chemistry, Central University of Punjab, Bathinda, 151401, India., Kumar V; Laboratory of Organic Synthesis and Catalysis, Department of Chemistry, Central University of Punjab, Bathinda, 151401, India., Verma PK; School of Advanced Chemical Sciences, Shoolini University, Solan, Himachal Pradesh, 173229, India., Kumar R; Laboratory of Organic Synthesis and Catalysis, Department of Chemistry, Central University of Punjab, Bathinda, 151401, India. rakesh.kumar@cup.edu.in.

Πηγή: Molecular diversity [Mol Divers] 2025 Jun; Vol. 29 (3), pp. 2811-2827. Date of Electronic Publication: 2024 Nov 10.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Triazoles*/chemistry , Triazoles*/chemical synthesis , Cycloaddition Reaction*/methods , Click Chemistry*/methods, Alkynes/chemistry ; Catalysis ; Decarboxylation ; Azides/chemistry

1,3-Dipolar Cycloaddition and Mannich Reactions of Alkynyl Triterpenes: New Trends in Synthetic Strategies and Pharmacological Applications.

Συγγραφείς: Petrova AV; Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Science, 69, Prospect Octyabrya, Ufa 450054, Russia., Kazakova OB; Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Science, 69, Prospect Octyabrya, Ufa 450054, Russia.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2025 May 02; Vol. 26 (9). Date of Electronic Publication: 2025 May 02.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Triterpenes*/chemistry , Triterpenes*/chemical synthesis , Triterpenes*/pharmacology , Cycloaddition Reaction*/methods , Alkynes*/chemistry, Humans ; Mannich Bases/chemistry ; Mannich Bases/chemical synthesis ; Triazoles/chemistry ; Triazoles/chemical synthesis ; Antiviral Agents/chemical synthesis ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Animals

Catalyst-controlled regiodivergence and stereodivergence in formal cross-[4+2] cycloadditions: The unique effect of bismuth(III).

Συγγραφείς: Hou Q; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China., Cai C; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China., Liu SJ; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China., Huang W; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China., Peng C; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China., Zhan G; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China., Han B; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Πηγή: Science advances [Sci Adv] 2025 Mar 28; Vol. 11 (13), pp. eadt5997. Date of Electronic Publication: 2025 Mar 26.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction* , Bismuth*/chemistry, Catalysis ; Stereoisomerism ; Humans ; Cell Line, Tumor ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Molecular Structure

Diels-Alder reaction in hydrogel synthesis: Mechanisms and functional aspects.

Συγγραφείς: Zhou YG; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Li SK; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Xue Y; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Fan B; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Gao QM; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Zhan LW; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Liu RT; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Li YF; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Sun RL; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China., Tian YZ; The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, China.

Πηγή: Journal of biomaterials applications [J Biomater Appl] 2025 Mar; Vol. 39 (8), pp. 828-839. Date of Electronic Publication: 2024 Dec 13.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Sage Publications Country of Publication: England NLM ID: 8813912 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-8022 (Electronic) Linking ISSN: 08853282 NLM ISO Abbreviation: J Biomater Appl Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction*/methods , Hydrogels*/chemistry , Hydrogels*/chemical synthesis , Biocompatible Materials*/chemistry , Biocompatible Materials*/chemical synthesis, Humans ; Drug Delivery Systems ; Polymers/chemistry

Development of Transiently Strainable Benzocycloheptenes for Catalyst-Free, Visible-Light-Mediated [3 + 2]-Cycloadditions.

Συγγραφείς: Kharbanda S; Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States., Alkhamayseh O; Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States., Eastham G; Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States., Weaver JD; Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.

Πηγή: Bioconjugate chemistry [Bioconjug Chem] 2025 Feb 19; Vol. 36 (2), pp. 302-308. Date of Electronic Publication: 2025 Feb 04.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction*/methods , Light* , Cycloheptanes*/chemistry , Cycloheptanes*/chemical synthesis, Catalysis ; Photochemical Processes ; Triazoles/chemistry ; Triazoles/chemical synthesis

TPDYs: strained macrocyclic diynes for bioconjugation processes.

Συγγραφείς: D'Onofrio B; Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, QC, H2V 0B3, Canada. shawn.collins@umontreal.ca., Cruché C; Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, QC, H2V 0B3, Canada. shawn.collins@umontreal.ca., Hurdal KN; Department of Chemistry, University of Manitoba, 144 Dysart Rd., Winnipeg, MB, R3T, Canada., Hadjabdelhafid-Parisien A; Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, QC, H2V 0B3, Canada. shawn.collins@umontreal.ca., Pelletier JN; Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, QC, H2V 0B3, Canada. shawn.collins@umontreal.ca., Iftimie R; Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, QC, H2V 0B3, Canada. shawn.collins@umontreal.ca., Davis RL; Department of Chemistry, University of Manitoba, 144 Dysart Rd., Winnipeg, MB, R3T, Canada., Collins SK; Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, QC, H2V 0B3, Canada. shawn.collins@umontreal.ca.

Πηγή: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2025 Jan 07; Vol. 61 (4), pp. 681-684. Date of Electronic Publication: 2025 Jan 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Macrocyclic Compounds*/chemistry , Macrocyclic Compounds*/chemical synthesis , Diynes*/chemistry , Cycloaddition Reaction*, Transglutaminases/chemistry ; Transglutaminases/metabolism ; Molecular Structure ; Alkynes/chemistry ; Triazoles/chemistry

Non-Hydrolysable ADP-Ribosylated SUMO2 via Copper(I) Catalyzed Azide Alkyne Cycloaddition.

Συγγραφείς: Heijne MD; Department of Cell and Chemical Biology, Leiden University Medical Centre, Leiden, The Netherlands., van der Heden van Noort GJ; Department of Cell and Chemical Biology, Leiden University Medical Centre, Leiden, The Netherlands. gvanderheden@lumc.nl.

Πηγή: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2957, pp. 183-190.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Copper*/chemistry , Alkynes*/chemistry , Azides*/chemistry , Cycloaddition Reaction*/methods , ADP-Ribosylation* , Small Ubiquitin-Related Modifier Proteins*/chemistry , Small Ubiquitin-Related Modifier Proteins*/metabolism , Adenosine Diphosphate Ribose*/chemistry , Adenosine Diphosphate Ribose*/metabolism, Humans ; Catalysis ; Click Chemistry

Genetically encoded artificial photoenzymes for enantioselective [2 + 2] photocycloadditions.

Συγγραφείς: Guo J; Key Laboratory for Green Chemical Process of Ministry of Education & Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, P. R China., Wu Y; Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica, Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, Huazhong University of Science and Technology (HUST), Wuhan, P. R China. Electronic address: wuyuzhou@hust.edu.cn., Zhong F; Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica, Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, Huazhong University of Science and Technology (HUST), Wuhan, P. R China. Electronic address: chemzfr@hust.edu.cn.

Πηγή: Methods in enzymology [Methods Enzymol] 2025; Vol. 721, pp. 211-235. Date of Electronic Publication: 2025 Sep 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7988 (Electronic) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction*/methods , Protein Engineering*/methods, Stereoisomerism ; Photochemical Processes ; Biocatalysis ; Benzophenones/chemistry

Acquiring stereospecific new pseudosugars: Obtaining rac-decahydro-1,4-epoxynaphthalene-2,3,5,6,7,8-hexaols from the Diels-Alder reaction and investigating their biological effects.

Συγγραφείς: Aydın G; Vocational School of Healty Services, Karamanoglu Mehmetbey University, Karaman 70200, Turkey., Çoban CÇ; Karadeniz Technical University Academic Data Management System, 61080, Trabzon, Turkey., Kurbanoğlu Nİ; Sakarya University, Faculty of Education Department of Mathematics and Science Education, 54050 Sakarya, Turkey., Türk M; Bioengineering Department, Faculty of Engineering and Architecture, Kırıkkale University, Kırıkkale 71451, Turkey., Baran A; Sakarya University, Faculty of Arts and Sciences, Chemistry Department, 54050, Sakarya, Turkey. Electronic address: abaran@sakarya.edu.tr.

Πηγή: Bioorganic chemistry [Bioorg Chem] 2025 Jan; Vol. 154, pp. 108078. Date of Electronic Publication: 2024 Dec 19.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Naphthalenes*/chemistry , Naphthalenes*/pharmacology , Naphthalenes*/chemical synthesis , alpha-Glucosidases*/metabolism , alpha-Amylases*/antagonists & inhibitors , alpha-Amylases*/metabolism , Cycloaddition Reaction*, Humans ; Structure-Activity Relationship ; Molecular Structure ; Glycoside Hydrolase Inhibitors/pharmacology ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/chemical synthesis ; Dose-Response Relationship, Drug ; Stereoisomerism

Synthesis of novel spiroisoxazolidino hybrids of alantolactone and isoalantolactone via 1,3 dipolar nitrone cycloaddition and its antimicrobial Evaluation.

Συγγραφείς: Tabassum A; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Kumari D; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Bhore HB; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India., Palmo T; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Venkatesan I; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India., Samanta J; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India., Katare AK; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Singh K; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: singh.kuljit@iiim.res.in., Bharitkar YP; CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: yogeshp.bharitkar@iiim.res.in.

Πηγή: Bioorganic chemistry [Bioorg Chem] 2025 Jan; Vol. 154, pp. 108087. Date of Electronic Publication: 2024 Dec 20.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cycloaddition Reaction* , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry , Microbial Sensitivity Tests* , Nitrogen Oxides*/chemistry , Nitrogen Oxides*/pharmacology, Structure-Activity Relationship ; Molecular Structure ; Lactones/chemistry ; Lactones/pharmacology ; Lactones/chemical synthesis ; Spiro Compounds/chemistry ; Spiro Compounds/pharmacology ; Spiro Compounds/chemical synthesis ; Dose-Response Relationship, Drug ; Sesquiterpenes/pharmacology ; Sesquiterpenes/chemistry ; Sesquiterpenes/chemical synthesis ; Isoxazoles/pharmacology ; Isoxazoles/chemistry ; Isoxazoles/chemical synthesis ; Staphylococcus aureus/drug effects