Amelioration of cisplatin-induced myocardial injury by nanocurcumin through antioxidant, anti-inflammatory, and calcium regulatory mechanisms

Συγγραφείς: Alqahtani, Qamraa H, ALMatrafi, Tahani A, Mohammed, Raeesa, Mahmoud, Ayman M, Hasan, Iman H

Πηγή: Journal of Molecular Histology. 57

Θεματικοί όροι: Male, Cisplatin - adverse effects, Curcumin, Apoptosis - drug effects, Anti-Inflammatory Agents, Apoptosis, Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism, Cardioprotection, Antioxidants, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Calcium homeostasis, Curcumin - pharmacology - therapeutic use, Animals, Cardiotoxicity - drug therapy, Rats, Wistar, Inflammation, Antioxidants - pharmacology, Myocardium, S100 Proteins, Calcium - metabolism, Myocardium - pathology - metabolism, Anti-Inflammatory Agents - pharmacology - therapeutic use, Cardiotoxicity, Rats, Nanoparticles - chemistry, Oxidative Stress, Oxidative Stress - drug effects, Oxidative stress, Nanoparticles, Calcium, Cisplatin

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41254419
https://e-space.mmu.ac.uk/643149/

Curcumin protects heart tissue against irinotecan-induced damage in terms of cytokine level alterations, oxidative stress, and histological damage in rats

Συγγραφείς: Çiftçi, Osman, Turkmen, N.B., Taslıdere, A.

Πηγή: Naunyn-Schmiedeberg's Archives of Pharmacology. 391:783-791

Θεματικοί όροι: Male, 0301 basic medicine, antioxidant, Anti-Inflammatory Agents, antioxidant activity, animal cell, heart tissue, Antioxidants, Rats, Sprague-Dawley, analogs and derivatives, inflammatory cell, caspase 3, cytokine, heart injury, oxidative stress, curcumin, rat, animal, cardiotonic agent, glutathione, glutathione peroxidase, irinotecan, antineoplastic agent, comparative study, Curcuma longa, 0303 health sciences, Sprague Dawley rat, catalase, drug effect, superoxide dismutase, 3. Good health, nicotinamide adenine dinucleotide phosphate, histopathology, Cytokines, blood sampling, Histological alterations, antiinflammatory agent, Cardiotonic Agents, Curcumin, tumor necrosis factor, thiobarbituric acid reactive substance, animal experiment, cardiotoxicity, Irinotecan, interleukin 4, Article, animal tissue, heart protection, 03 medical and health sciences, male, glutathione disulfide, bovine serum albumin, reduced nicotinamide adenine dinucleotide phosphate, Animals, controlled study, Anti-Inflammatory Agents/pharmacology/*therapeutic use, Antineoplastic Agents, Phytogenic, Antioxidants/pharmacology/*therapeutic use, Camptothecin/analogs & derivatives, Cardiotonic Agents/pharmacology/*therapeutic use, Cardiotoxicity/*drug therapy/metabolism/pathology, Curcumin/pharmacology/*therapeutic use, Cytokines/metabolism, Oxidative Stress/drug effects, Rats, Cytokine, glutathione reductase, nonhuman, animal model, camptothecin, antiinflammatory activity, Cardiotoxicity, Oxidative Stress, Oxidative stress, protein blood level, pathology, Camptothecin, metabolism

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/29721577
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/10691

Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFκB, cyclinD and MMP-1 transcription

Συγγραφείς: Tong, Y, Liu, Q, Sze, SCW, Loo, WTY

Πηγή: Phytomedicine. 16:916-922

Θεματικοί όροι: 0301 basic medicine, Curcumin, CyclinD1/CDK4, Down-Regulation, Breast Neoplasms, Adenocarcinoma, 03 medical and health sciences, Curcuma, Cell Line, Tumor, Cyclin D, Curcumin - pharmacology - therapeutic use, Humans, Curcuma longa, Cell Proliferation, 0303 health sciences, Plant Extracts, Matrix Metalloproteinase 1 - metabolism, NF-kappa B, Cyclin-Dependent Kinase 4, NF-kappa B - metabolism, Immunohistochemistry, 3. Good health, p21-Activated Kinases, Cell Proliferation - drug effects, Female, MMPs, Cyclin D - metabolism, Drug Screening Assays, Antitumor, Matrix Metalloproteinase 1, NFκB, Phytotherapy

Σύνδεσμος πρόσβασης: http://hub.hku.hk/bitstream/10722/60791/1/Content.pdf
https://pubmed.ncbi.nlm.nih.gov/19524420
http://hdl.handle.net/10722/60791

Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition

Συγγραφείς: Choi, Hyunsung, Chun, Yang-Sook, Kim, Seung-Won, Kim, Myung-Suk, Park, Jong-Wan

Συνεισφορές: 최현성, 전양숙, 김승원, 김명석, 박종완

Θεματικοί όροι: Animals, Antineoplastic Agents, Phytogenic/*pharmacology, Aryl Hydrocarbon Receptor Nuclear Translocator/genetics/*metabolism, Cell Division/drug effects, Cell Hypoxia/drug effects, Curcumin/*pharmacology/*therapeutic use, Down-Regulation/drug effects, Gene Expression Regulation, Neoplastic/drug effects, Humans, Hypoxia-Inducible Factor 1/*antagonists & inhibitors/metabolism, Male, Mice, Nude, Neoplasms/drug therapy/*pathology, Oxidation-Reduction/drug effects, Oxidative Stress/drug effects, Proteasome Endopeptidase Complex/metabolism, Protein Processing, Post-Translational/*drug effects, Protein Subunits/metabolism, RNA, Messenger/genetics/metabolism, Transcription, Genetic/drug effects, Tumor Cells, Cultured, Ubiquitin/metabolism

Relation: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16880289; https://hdl.handle.net/10371/29608

Διαθεσιμότητα: https://hdl.handle.net/10371/29608
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16880289
https://doi.org/10.1124/mol.106.025817