T-cell and monocyte DNA methylation and Wnt dysregulation in common variable immunodeficiency: an exploratory study.

Authors: Myhre V; Research Institute of Internal Medicine, Division of Surgery and Specialized Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Yang M; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Kaarbø M; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Fraz MSA; Research Institute of Internal Medicine, Division of Surgery and Specialized Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Michelsen AE; Research Institute of Internal Medicine, Division of Surgery and Specialized Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Fevang B; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Aukrust P; Research Institute of Internal Medicine, Division of Surgery and Specialized Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Ueland T; Research Institute of Internal Medicine, Division of Surgery and Specialized Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Faculty of Health Sciences, K.G. Jebsen Centre for Thrombosis Research (TREC), University of Tromsø, Tromsø, Norway., Bjørås M; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Microbiology, University of Oslo, Oslo, Norway., Jørgensen SF; Research Institute of Internal Medicine, Division of Surgery and Specialized Medicine, Oslo University Hospital, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

Source: Frontiers in immunology [Front Immunol] 2026 Oct 01; Vol. 17, pp. 1931297. Date of Electronic Publication: 2026 Oct 01 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Monocytes*/immunology , Monocytes*/metabolism , Wnt Signaling Pathway*/genetics , Wnt Signaling Pathway*/immunology , DNA Methylation*, Humans ; Female ; Male ; Adult ; Epigenesis, Genetic ; Middle Aged ; CpG Islands

Nuclear Factor Kappa B (NF-κB)1 and NF-κB2 Deficiency: An Unpredictable Defect With Wide Clinical and Immunologic Phenotype.

Authors: Sevinç S; Department of Pediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., İslamoğlu C; Department of Pediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Haskoloğlu Ş; Department of Pediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Öztürk G; Department of Pediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Bal SK; Department of Pediatric Immunology and Allergy, Gülhane Training and Research Hospital, Ankara, Türkiye., Aslan AD; Department of Pediatric Intensive Care, Ankara University Faculty of Medicine, Ankara, Türkiye., Şahap SK; Department of Pediatric Radiology, Ankara University Faculty of Medicine, Ankara, Türkiye., Ersöz CC; Department of Pathology, Ankara University Faculty of Medicine, Ankara, Türkiye., Kendirli T; Department of Pediatric Intensive Care, Ankara University Faculty of Medicine, Ankara, Türkiye., Doğu F; Department of Pediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., İkincioğulları A; Department of Pediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye.

Source: Scandinavian journal of immunology [Scand J Immunol] 2026 Sep; Vol. 104 (3), pp. e70142.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0323767 Publication Model: Print Cited Medium: Internet ISSN: 1365-3083 (Electronic) Linking ISSN: 03009475 NLM ISO Abbreviation: Scand J Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/immunology , Immunologic Deficiency Syndromes*/genetics , NF-kappa B p50 Subunit*/genetics , NF-kappa B p50 Subunit*/deficiency , NF-kappa B p50 Subunit*/immunology , NF-kappa B p52 Subunit*/deficiency , NF-kappa B p52 Subunit*/genetics , NF-kappa B p52 Subunit*/immunology, Mutation/genetics ; Humans ; Phenotype ; Signal Transduction

Coexistent alterations of BAFF and B-cell phenotypes in complicated CVID course.

Authors: Matson EM; Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass., Ware MS; Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass., Feng F; Department of Virology, Immunology, and Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass., Yu L; Department of Computational Biomedicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass., Beane JE; Department of Computational Biomedicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass., Belkina AC; Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass; Flow Cytometry Core Facility, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass., Maglione PJ; Pulmonary Center, Section of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass. Electronic address: pmaglion@bu.edu.

Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 Sep; Vol. 158 (3), pp. 908-921.e6. Date of Electronic Publication: 2026 May 30.

Publication Type: Journal Article

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

MeSH Terms: B-Cell Activating Factor*/immunology , B-Cell Activating Factor*/blood , B-Cell Activating Factor*/genetics , Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/genetics , B-Lymphocytes*/immunology , B-Lymphocyte Subsets*/immunology, B-Cell Activation Factor Receptor/genetics ; B-Cell Activation Factor Receptor/immunology ; Transmembrane Activator and CAML Interactor Protein/genetics ; Transmembrane Activator and CAML Interactor Protein/immunology ; Transmembrane Activator and CAML Interactor Protein/blood ; Humans ; Female ; Phenotype ; Male ; Adult ; Lymphocyte Activation ; Cytopenia

Beyond B cells: T and Innate Immune Mechanisms of Autoimmunity in Common Variable Immunodeficiency.

Authors: Kowalczyk P; 3P-Medicine Laboratory, Medical University of Gdansk, 7 Dębinki st, Gdansk, 80-211, Poland. kowalczyk.paulina@gumed.edu.pl., Zima K; Department of Physiology, Medical University of Gdansk, 1 Debinki st, Gdansk, 80-211, Poland., Sowa-Rogozińska N; Department of Physiology, Medical University of Gdansk, 1 Debinki st, Gdansk, 80-211, Poland., Majewska-Szczepanik M; Chair of Biomedical Sciences, Department of Medical Physiology, Faculty of Health Sciences, Jagiellonian University Medical College, 12 Michalowskiego st., Cracow, 33-332, Poland., Ziętkiewicz M; Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, 7 Dębinki st, Gdansk, 80-211, Poland. marcin.zietkiewicz@gumed.edu.pl.

Source: Clinical reviews in allergy & immunology [Clin Rev Allergy Immunol] 2026 Aug 28; Vol. 69 (1). Date of Electronic Publication: 2026 Aug 28.

Publication Type: Journal Article; Review

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9504368 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0267 (Electronic) Linking ISSN: 10800549 NLM ISO Abbreviation: Clin Rev Allergy Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/metabolism , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Immunity, Innate* , Autoimmunity*, Cytokines/metabolism ; Humans ; Animals ; Signal Transduction

Prevalence, associated clinical factors, and genetic characteristics of endocrinopathies in common variable immunodeficiency: a retrospective study of 95 adult patients from a single tertiary care center.

Authors: Yigitdol I; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Colkesen F; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Gerek ME; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Yilmaz Ergun U; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Kolak S; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Harman E; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Sagun F; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Aslan Savas S; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye., Arslan S; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Türkiye.

Source: Frontiers in immunology [Front Immunol] 2026 Aug 24; Vol. 17, pp. 1882721. Date of Electronic Publication: 2026 Aug 24 (Print Publication: 2026).

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/epidemiology , Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/immunology , Endocrine System Diseases*/epidemiology , Endocrine System Diseases*/genetics , Endocrine System Diseases*/etiology, Glucocorticoids/adverse effects ; Humans ; Female ; Male ; Retrospective Studies ; Adult ; Prevalence ; Middle Aged ; Tertiary Care Centers ; Aged ; Young Adult

Multidisciplinary Delphi consensus on malignancy screening in patients with common variable immunodeficiency.

Authors: Cabanero-Navalon MD; Primary Immunodeficiency Unit, Department of Internal Medicine, La Fe University and Polytechnic Hospital, Valencia, Spain., de Andrés-Martín A; Department of Immunology, Ramón y Cajal University Hospital, Madrid, Spain., Gil AA; Department of Internal Medicine, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; Adult Primary Immunodeficiency Unit, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain., Bracke C; Fundació Lluita contra les Infeccions, Germans Trias i Pujol University Hospital, Badalona, Spain.; Department of Infectious Diseases, Germans Trias i Pujol University Hospital, Badalona, Spain., Carrillo-Linares JL; Department of Internal Medicine, Virgen de la Victoria University Hospital, Málaga, Spain.; Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina, IBIMA Plataforma BIONAND, Málaga, Spain., Cos ML; Primary Immunodeficiencies Functional Unit, Hospital del Mar, Barcelona, Spain.; Department of Internal Medicine, Hospital del Mar, Barcelona, Spain., Gasior M; Department of Hematology, La Paz University Hospital, Madrid, Spain., Gil-Niño J; Department of Internal Medicine, 12 de Octubre University Hospital, Madrid, Spain., González-Granado LI; Department of Pediatrics, Primary Immunodeficiencies Unit, 12 de Octubre University Hospital, Institute for Health Research (imas12), Madrid, Spain.; Complutense University School of Medicine, Madrid, Spain., López Osle N; Internal Medicine, Biobizkaia Health Research Institute, Barakaldo, Bizkaia, Spain.; Osakidetza, Cruces University Hospital, Barakaldo, Bizkaia, Spain., Robles-Marhuenda Á; Department of Internal Medicine, La Paz University Hospital, Madrid, Spain.; Working Group on Rare Diseases, Spanish Society of Internal Medicine (GTEM-SEMI), Madrid, Spain., Sánchez Martínez R; Internal medicine department - General Hospital Health Department, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain., Sánchez-Ramón S; Department of Clinical Immunology, San Carlos University Clinical Hospital, Madrid, Spain., Soler-Palacin P; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain.; Infection and Immunity in Pediatric Patients Research Group, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain., Solanich X; Department of Internal Medicine, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; Adult Primary Immunodeficiency Unit, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Torralba-Cabeza MÁ; Department of Internal Medicine, Lozano Blesa University Clinical Hospital, Zaragoza, Spain.; Aragon Health Research Institute, Zaragoza, Spain.; Working Group on Rare Diseases, Spanish Society of Internal Medicine, Zaragoza, Spain., Aparicio Tormo JR; Endoscopy Unit, Dr. Balmis General University Hospital, Alicante, Spain., Alsina L; Pediatric Allergy and Clinical Immunology Department, Clinical Immunology and Primary Immunodeficiencies Unit, Sant Joan de Déu Hospital, Barcelona, Spain.; Department of Surgery and Surgical Specialties, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children (GEMDIP), Sant Joan de Déu Research Institute (IRSJD), Barcelona, Spain., Moral Moral P; Primary Immunodeficiency Unit, Department of Internal Medicine, La Fe University and Polytechnic Hospital, Valencia, Spain.

Source: Frontiers in immunology [Front Immunol] 2026 Aug 17; Vol. 17, pp. 1897051. Date of Electronic Publication: 2026 Aug 17 (Print Publication: 2026).

Publication Type: Journal Article; Consensus Statement

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/epidemiology , Common Variable Immunodeficiency*/diagnosis , Early Detection of Cancer*/methods , Neoplasms*/diagnosis , Neoplasms*/etiology , Neoplasms*/epidemiology, Spain/epidemiology ; Humans ; Delphi Technique ; Adult ; Risk Factors

Elevated IL-10 is Linked With the Expansion of T-bet^highCD21^low B Cells in Patients With Common Variable Immunodeficiency.

Authors: Cousin V; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Schaenzlestrasse 1, 79104, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany., Graumann A; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Geiger V; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Schaenzlestrasse 1, 79104, Freiburg, Germany., Sökler D; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Bez P; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine (DIMED), University of Padova, Padua, Italy., Gutenberger S; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Glaser C; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between, DKFZ and Medical Center - University of Freiburg, Freiburg, Germany., Frye BC; Clinic for Pneumology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany., Zissel G; Clinic for Pneumology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany., Calvillo CL; Epigenetics and Immune Disease Group, Josep Carreras Leukaemia Research Institute (IJC), Badalona, 08916, Barcelona, Spain., Rodriguez-Ubreva J; Epigenetics and Immune Disease Group, Josep Carreras Leukaemia Research Institute (IJC), Badalona, 08916, Barcelona, Spain., Ballestar E; Epigenetics and Immune Disease Group, Josep Carreras Leukaemia Research Institute (IJC), Badalona, 08916, Barcelona, Spain.; Epigenetics in Inflammatory and Metabolic Diseases Laboratory, Health Science Center (HSC), East China Normal University (ECNU), Shanghai, China., Hauck F; Division of Pediatric Immunology and Rheumatology, Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität (LMU), Munich, Germany., Voll RE; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Chevalier N; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Keller B; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Warnatz K; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. klaus.warnatz@uniklinik-freiburg.de.; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. klaus.warnatz@uniklinik-freiburg.de.

Source: Journal of clinical immunology [J Clin Immunol] 2026 Aug 15; Vol. 46 (1). Date of Electronic Publication: 2026 Aug 15.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8102137 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2592 (Electronic) Linking ISSN: 02719142 NLM ISO Abbreviation: J Clin Immunol Subsets: MEDLINE

MeSH Terms: Interleukin-10*/blood , Interleukin-10*/metabolism , Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/metabolism , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism, Receptors, Complement 3d/metabolism ; Cell Differentiation/immunology ; STAT3 Transcription Factor/metabolism ; Interleukins/metabolism ; Lymphocyte Activation/immunology ; B-Lymphocyte Subsets/immunology ; Humans ; Female ; Male ; Interleukin-21 ; Signal Transduction ; Adult

25-Hydroxyvitamin D Sufficiency Is Associated With Reduced Atelectasis in Common Variable Immunodeficiency: A Cross-Sectional Study.

Authors: Silveira C; Division of Clinical Immunology and Allergy, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil., Barros MT; Division of Clinical Immunology and Allergy, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil., Coutinho Martins É; Division of Clinical Immunology and Allergy, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil., Grecco O; Division of Clinical Immunology and Allergy, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil., Kokron C; Division of Clinical Immunology and Allergy, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil.; Institute for Investigation in Immunology, National Institute of Science and Technology (iii-INCT), University of São Paulo, São Paulo, SP, Brazil., Kalil J; Division of Clinical Immunology and Allergy, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil.; Institute for Investigation in Immunology, National Institute of Science and Technology (iii-INCT), University of São Paulo, São Paulo, SP, Brazil.

Source: Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2026 Sep 18; Vol. 32, pp. e953313. Date of Electronic Publication: 2026 Sep 18.

Publication Type: Journal Article

Journal Info: Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 9609063 Publication Model: Electronic Cited Medium: Internet ISSN: 1643-3750 (Electronic) Linking ISSN: 12341010 NLM ISO Abbreviation: Med Sci Monit Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/blood , Vitamin D*/analogs & derivatives , Vitamin D*/blood , Pulmonary Atelectasis*/blood , Pulmonary Atelectasis*/etiology, Vitamin D Deficiency/blood ; Vitamin D Deficiency/complications ; Humans ; Cross-Sectional Studies ; Female ; Male ; Retrospective Studies ; Adult ; Middle Aged ; Bronchiectasis ; Pulmonary Disease, Chronic Obstructive

The immunogenic cross-talk in pediatric MASLD: does subclinical immune dysfunction accelerate early hepatic destruction?

Authors: Mangge H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.

Source: Frontiers in immunology [Front Immunol] 2026 Sep 17; Vol. 17, pp. 1930909. Date of Electronic Publication: 2026 Sep 17 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Liver*/immunology , Liver*/pathology , Liver*/metabolism , Common Variable Immunodeficiency*/immunology , Fatty Liver*/immunology , Fatty Liver*/pathology , Fatty Liver*/metabolism , Fatty Liver*/etiology, Inflammasomes/metabolism ; Pediatric Obesity/immunology ; Humans ; Child ; Animals ; Adaptive Immunity

Mucosal regulatory and effector T-cell imbalance in CVID-associated enteropathy.

Authors: Demir S; Division of Immunology and Allergy Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Kahveci N; Division of Immunology and Allergy Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Gelmez MY; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye., Unal D; Division of Immunology and Allergy Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Yegit OO; Division of Immunology and Allergy Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Yagli MA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., İstemihan Z; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Berker N; Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Cavus B; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Besisik F; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Cetin Aktas E; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye., Gelincik A; Division of Immunology and Allergy Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye., Deniz G; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Türkiye.

Source: Frontiers in immunology [Front Immunol] 2026 Sep 03; Vol. 17, pp. 1937502. Date of Electronic Publication: 2026 Sep 03 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/complications , T-Lymphocytes, Regulatory*/immunology , T-Lymphocytes, Regulatory*/metabolism , Intestinal Mucosa*/immunology , Intestinal Mucosa*/pathology , Intestinal Mucosa*/metabolism , T-Lymphocyte Subsets*/immunology , T-Lymphocyte Subsets*/metabolism , Intestinal Diseases*/immunology , Intestinal Diseases*/etiology, Duodenum/immunology ; Duodenum/pathology ; Cytokines/metabolism ; Ileum/immunology ; Ileum/pathology ; Humans ; Female ; Male ; Adult ; Middle Aged ; Young Adult ; Immunity, Mucosal

Growth differentiation factor 15 in common variable immunodeficiency patients: Diagnostic value and prediction of autoimmunity risk.

Authors: Karatopuk G; From the Department of Internal Medicine, Cukurca State Hospital, Hakkari, Turkey., Colkesen F; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Turkey., Ugrakli S; Department of Medical Microbiology, Necmettin Erbakan University, Faculty of Medicine, Konya, Turkey; and., Gerek ME; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Turkey., Yildiz E; Division of Clinical Immunology and Allergy, Necip Fazil City Hospital, Kahramanmaras, Turkey., Arslan S; Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Faculty of Medicine, Konya, Turkey.

Source: Allergy and asthma proceedings [Allergy Asthma Proc] 2026 Sep 01; Vol. 47 (5), pp. e81-e88.

Publication Type: Journal Article

Journal Info: Publisher: OceanSide Publications Country of Publication: United States NLM ID: 9603640 Publication Model: Print Cited Medium: Internet ISSN: 1539-6304 (Electronic) Linking ISSN: 10885412 NLM ISO Abbreviation: Allergy Asthma Proc Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/diagnosis , Common Variable Immunodeficiency*/blood , Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/complications , Growth Differentiation Factor 15*/blood , Autoimmune Diseases*/diagnosis , Autoimmunity*, Biomarkers/blood ; Humans ; Female ; Male ; Adult ; Cross-Sectional Studies ; ROC Curve ; Prospective Studies ; Middle Aged ; Case-Control Studies ; Risk Factors ; Young Adult

Gastrointestinal manifestations of common variable immunodeficiency: what a gastroenterologist needs to be aware of.

Authors: Levy DM; Department of Medicine, Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX, USA., Meriwether M; Division of Gastroenterology Hepatology and Lynda K and David M Underwood Center for Digestive Health, Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX, USA., Schwartz MR; Department of Pathology and Genomic Medicine, Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX, USA., Bishu S; Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA., Quigley EMM; Division of Gastroenterology Hepatology and Lynda K and David M Underwood Center for Digestive Health, Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX, USA.

Source: Expert review of gastroenterology & hepatology [Expert Rev Gastroenterol Hepatol] 2026 Aug; Vol. 20 (8), pp. 673-682. Date of Electronic Publication: 2026 Aug 17.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101278199 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4132 (Electronic) Linking ISSN: 17474124 NLM ISO Abbreviation: Expert Rev Gastroenterol Hepatol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/diagnosis , Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/therapy , Common Variable Immunodeficiency*/epidemiology , Gastrointestinal Diseases*/therapy , Gastrointestinal Diseases*/diagnosis , Gastrointestinal Diseases*/immunology , Gastrointestinal Diseases*/etiology , Gastrointestinal Diseases*/epidemiology, Humans ; Diagnosis, Differential ; Gastroenterologists ; Prognosis ; Predictive Value of Tests ; Risk Factors

Granulomatous Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency.

Authors: Benor S; Department of Allergy and Clinical Immunology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Hentschel F; Department of Allergy and Clinical Immunology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Freund T; Department of Allergy and Clinical Immunology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Hagin D; Department of Allergy and Clinical Immunology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Source: The Israel Medical Association journal : IMAJ [Isr Med Assoc J] 2026 Aug; Vol. 28 (8), pp. 500-507.

Publication Type: Journal Article

Journal Info: Publisher: Israel Medical Association Country of Publication: Israel NLM ID: 100930740 Publication Model: Print Cited Medium: Internet ISSN: 3135-8225 (Electronic) NLM ISO Abbreviation: Isr Med Assoc J Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/diagnosis , Lung Diseases, Interstitial*/etiology , Lung Diseases, Interstitial*/immunology , Lung Diseases, Interstitial*/diagnosis , Lung Diseases, Interstitial*/physiopathology , Granuloma*, B-Lymphocytes/immunology ; T-Lymphocytes/immunology ; Humans ; Female ; Male ; Adult ; Immunophenotyping ; Middle Aged

Advances in the Phenotyping and Management of Common Variable Immunodeficiency.

Authors: Gill ME; Clinical Immunodeficiency Program, Beth Israel Lahey Health, Division of Allergy & Immunology, Lahey Clinic, Burlington, MA, USA., Jogdand A; Clinical Immunodeficiency Program, Beth Israel Lahey Health, Division of Allergy & Immunology, Lahey Clinic, Burlington, MA, USA., Schissel C; Translational Research Program, Division of Allergy & Immunology, Lahey Clinic, Burlington, MA, USA., Ong MS; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA., Barmettler S; Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA., Farmer JR; Clinical Immunodeficiency Program, Beth Israel Lahey Health, Division of Allergy & Immunology, Lahey Clinic, Burlington, MA, USA; Department of Medicine, UMass Chan Medical School, Lahey Clinic, Burlington, MA, USA. Electronic address: jocelyn.farmer@lahey.org.

Source: Immunology and allergy clinics of North America [Immunol Allergy Clin North Am] 2026 Nov; Vol. 46 (4), pp. 699-721. Date of Electronic Publication: 2026 Aug 05.

Publication Type: Journal Article; Review

Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8805635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8607 (Electronic) Linking ISSN: 08898561 NLM ISO Abbreviation: Immunol Allergy Clin North Am Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/diagnosis , Common Variable Immunodeficiency*/therapy , Common Variable Immunodeficiency*/etiology , Common Variable Immunodeficiency*/immunology, Humans ; Phenotype ; Disease Management ; Immunophenotyping

Clinical practice guideline for the diagnosis of granulomatous-lymphocytic interstitial lung disease in patients with common variable immunodeficiency disorders: an ERS Clinical Research Collaboration.

Authors: Bintalib HM; Department of Respiratory Care, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia hmbintalib@gmail.com.; King Abdullah International Medical Research Centre, Jeddah, Saudi Arabia.; Ministry of National Guard - Health Affairs, Jeddah, Saudi Arabia.; These authors contributed equally to this work., van de Ven AAJM; Department of Internal Medicine, Division of Allergology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, The Netherlands.; These authors contributed equally to this work., Rojas-Reyes MX; Evaluation Unit of the Canary Islands Health Service (SESCS), Tenerife, Spain., Davidsen JR; South Danish Center for Interstitial Lung Diseases, Department of Respiratory Medicine, Odense University Hospital, Odense, Denmark.; Odense Respiratory Research Unit (ODIN), Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Hanitsch LG; Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), BIH Center for Regenerative Therapies, Berlin, Germany., Cinetto F; Department of Medicine (DIMED), University of Padova, Rare Diseases Referral Center, Internal Medicine 1, AULSS2 Marca Trevigiana, Ca' Foncello Hospital, Treviso, Italy., Malphettes M; Department of Clinical Immunopathology, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris (APHP), Paris, France., Van Montfrans JM; Department of Pediatric Immunology and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands., Jacob J; Satsuma Lab, Hawkes Institute, University College London, London, UK.; UCL Respiratory, University College London, London, UK., Milito C; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Haerynck F; Department of Pediatric Pulmonology and Immunology, Centre for Primary Immune Deficiency Ghent, Ghent, Belgium.; PID Research Lab, University Hospital Ghent, Ghent, Belgium., Strauss F; DSAI - Deutsche Selbsthilfe Angeborene Immundefekte e.V., Stuttgart/Ulm, Germany., Cool C; University of Colorado Anschutz Medical Campus Aurora, Aurora, CO, USA., Calderon-Jaramillo M; Centre D'Estudis Demogràfics, Autonomous University of Barcelona, Barcelona, Spain., Lopez-Mujica X; Evaluation Unit of the Canary Islands Health Service (SESCS), Tenerife, Spain., Maglione P; Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA., Trujillo-Martin MM; Evaluation Unit of the Canary Islands Health Service (SESCS), Tenerife, Spain.; Canary Islands Health Research Institute Foundation, Tenerife, Spain.; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS), Tenerife, Spain., Fevang B; Department of Rheumatology, Dermatology and Infectious Diseases, Oslo University Hospital Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Routes J; Division of Asthma, Allergy and Clinical Immunology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Hurst JR; UCL Respiratory, University College London, London, UK.; These authors contributed equally to this work., Warnatz K; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Immunology, University Hospital Zurich (USZ), Zurich, Switzerland.; These authors contributed equally to this work.

Corporate Authors: ESID Clinical Guideline Working Party, ERS e-GLILDnet Clinical Research Collaboration

Source: The European respiratory journal [Eur Respir J] 2026 Sep 25; Vol. 68 (3). Date of Electronic Publication: 2026 Sep 25 (Print Publication: 2026).

Publication Type: Journal Article; Practice Guideline

Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/complications , Lung Diseases, Interstitial*/diagnosis , Lung Diseases, Interstitial*/complications, Lung/pathology ; Lung/diagnostic imaging ; Adult ; Humans ; Biopsy ; Europe ; Evidence-Based Medicine ; Respiratory Function Tests ; Tomography, X-Ray Computed ; Systematic Reviews as Topic

Altered duodenal N6-methyladenosine levels in common variable immunodeficiency associate with duodenal microbiota.

Authors: Myhre V; Division of Surgery and Specialized Medicine, Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Kaarbø M; Department of Microbiology, Oslo University Hospital and University of Oslo, Oslo, Norway., Yang M; Department of Microbiology, Oslo University Hospital and University of Oslo, Oslo, Norway.; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Fevang B; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Sousa MML; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.; Proteomics and Modomics Experimental Core Facility (PROMEC) at Norwegian University of Science and Technology, Trondheim, Norway., Reims HM; Department of Pathology, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Lundin KEA; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Hov JR; Division of Surgery and Specialized Medicine, Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Norwegian PSC Research Center, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway., Aukrust P; Division of Surgery and Specialized Medicine, Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Bjørås M; Department of Microbiology, Oslo University Hospital and University of Oslo, Oslo, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Jørgensen SF; Division of Surgery and Specialized Medicine, Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

Source: Frontiers in immunology [Front Immunol] 2026 Jul 08; Vol. 17, pp. 1875823. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/microbiology , Common Variable Immunodeficiency*/metabolism , Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/immunology , Adenosine*/analogs & derivatives , Adenosine*/metabolism , Duodenum*/microbiology , Duodenum*/metabolism , Duodenum*/immunology , Microbiota*, Humans ; Female ; RNA Methylation ; Adult ; Male ; Epitranscriptome ; Middle Aged ; Epitranscriptomics

Clinical and immunological characterization of NFKB1 haploinsufficiency in Japan.

Authors: Moriya K; Department of Pediatrics, National Defense Medical College, Saitama, Japan.; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan., Kamiyama Y; Department of Pediatrics, National Defense Medical College, Saitama, Japan.; Department of Pediatrics, Graduate School of Medicine, Yokohama City University, Yokohama, Japan., Ogino R; Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan., Kaneko S; Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Isoda T; Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Kamiya T; Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Sakai Y; Department of Pediatrics, National Defense Medical College, Saitama, Japan., Hirose F; Department of Pediatrics, National Defense Medical College, Saitama, Japan., Hagiwara H; Department of Pediatrics, National Defense Medical College, Saitama, Japan., Iwama I; Division of Gastroenterology and Hepatology, Saitama Children's Medical Center, Saitama, Japan., Nambu R; Division of Gastroenterology and Hepatology, Saitama Children's Medical Center, Saitama, Japan., Uejima Y; Department of Infectious Diseases and Immunology, Division of Infectious Diseases and Immunology, Saitama Children's Medical Center, Saitama, Japan., Sakura F; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan., Tsumura M; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan., Izawa K; Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan., Matsuda Y; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan., Nakatani N; Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan., Tamura A; Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan., Nozawa T; Department of Pediatrics, Graduate School of Medicine, Yokohama City University, Yokohama, Japan., Shimizu M; Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Wada T; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan., Okada S; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan., Kanegane H; Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Imai K; Department of Pediatrics, National Defense Medical College, Saitama, Japan.

Source: Frontiers in immunology [Front Immunol] 2026 Jul 08; Vol. 17, pp. 1866459. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: NF-kappa B p50 Subunit*/genetics , Agammaglobulinemia*/genetics , Agammaglobulinemia*/immunology , Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/immunology , Haploinsufficiency*, B-Lymphocytes/immunology ; Humans ; Female ; Male ; Adult ; Child ; Adolescent ; Japan ; Child, Preschool ; Young Adult ; Middle Aged ; Immunophenotyping ; Pedigree ; Phenotype

Non-invasive assessment of hepatic involvement in common variable immunodeficiency and agammaglobulinemia using enhanced liver fibrosis score and shearwave elastography.

Authors: Stojanovic M; Clinic of Allergy and Immunology, University Clinical Center of Serbia, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Stojkovic-Lalosevic M; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic of Gastroenterology and Hepatology, University Clinical Center of Serbia, Belgrade, Serbia., Stankovic S; Center for Medical Biochemistry, University Clinical Center of Serbia, Belgrade, Serbia.; Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia., Miskovic R; Clinic of Allergy and Immunology, University Clinical Center of Serbia, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Ljubicic J; Clinic of Allergy and Immunology, University Clinical Center of Serbia, Belgrade, Serbia., Rankovic I; Clinic of Gastroenterology and Hepatology, University Clinical Center of Serbia, Belgrade, Serbia., Pesic A; Clinic of Hematology, University Clinical Center of Serbia, Belgrade, Serbia., Dragasevic Vucicevic S; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic of Gastroenterology and Hepatology, University Clinical Center of Serbia, Belgrade, Serbia., Petrovic G; Institute for Health Care of Mother and Child of Serbia Dr. Vukan Cupic, Belgrade, Serbia., Bonaci-Nikolic B; Clinic of Allergy and Immunology, University Clinical Center of Serbia, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

Source: Frontiers in immunology [Front Immunol] 2026 Jun 24; Vol. 17, pp. 1857089. Date of Electronic Publication: 2026 Jun 24 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Elasticity Imaging Techniques*/methods , Liver Cirrhosis*/etiology , Liver Cirrhosis*/diagnosis , Liver Cirrhosis*/diagnostic imaging , Liver Cirrhosis*/blood , Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/diagnosis , Agammaglobulinemia*/complications , Agammaglobulinemia*/diagnosis , Liver*/pathology , Liver*/diagnostic imaging, Biomarkers/blood ; Hyaluronic Acid/blood ; Tissue Inhibitor of Metalloproteinase-1/blood ; Humans ; Female ; Male ; Cross-Sectional Studies ; Adult ; Middle Aged ; Young Adult ; Adolescent ; Severity of Illness Index

Clinical and immunological factors associated with gastrointestinal involvement in common variable immunodeficiency: a real-world study.

Authors: Harman E; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Çölkesen F; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey. neueriskinimmunoloji@gmail.com., Gerek ME; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Sağun F; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Kolak S; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Savaş ŞA; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Yiğitdöl İ; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Ergün ÜY; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey., Arslan Ş; Department of Immunology and Allergy Diseases, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye, Turkey.

Source: BMC immunology [BMC Immunol] 2026 Jun 22; Vol. 27 (1). Date of Electronic Publication: 2026 Jun 22.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966980 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2172 (Electronic) Linking ISSN: 14712172 NLM ISO Abbreviation: BMC Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/immunology , Common Variable Immunodeficiency*/complications , Common Variable Immunodeficiency*/diagnosis , B-Lymphocyte Subsets*/immunology , Gastrointestinal Diseases*/immunology , Gastrointestinal Diseases*/diagnosis , Memory B Cells*/immunology, Immunoglobulin M/blood ; Immunoglobulin A/blood ; B-Lymphocytes/immunology ; Humans ; Female ; Male ; Adult ; Middle Aged ; Retrospective Studies ; ROC Curve ; Immunologic Memory ; Immunophenotyping ; Aged

NF-κB1 haploinsufficiency due to a novel c.104delT variant in two patients with common variable immunodeficiency.

Authors: Bylica J; Department of Rheumatology, Immunology and Internal Medicine, University Hospital, Kraków, Poland. Electronic address: jan.bylica@alumni.uj.edu.pl., Karpiński M; Haematological Diagnostics and Genetics Unit, University Hospital, Kraków, Poland., Korkosz M; Department of Rheumatology, Immunology and Internal Medicine, University Hospital, Kraków, Poland; Department of Rheumatology and Immunology, Medical College, Jagiellonian University Medical College, Kraków, Poland., Kosałka-Węgiel J; Department of Rheumatology, Immunology and Internal Medicine, University Hospital, Kraków, Poland; Department of Rheumatology and Immunology, Medical College, Jagiellonian University Medical College, Kraków, Poland.

Source: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2026 Jun; Vol. 285, pp. 110703. Date of Electronic Publication: 2026 Mar 30.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 100883537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-7035 (Electronic) Linking ISSN: 15216616 NLM ISO Abbreviation: Clin Immunol Subsets: MEDLINE

MeSH Terms: Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/immunology , NF-kappa B p50 Subunit*/genetics , Haploinsufficiency*/genetics, Humans ; Female ; Young Adult ; Adult