Prevalence of Alzheimer’s disease pathology in the community

Authors: Dag Aarsland, Anita Lenora Sunde, Diego A. Tovar-Rios, Antoine Leuzy, Tormod Fladby, Henrik Zetterberg, Kaj Blennow, Kübra Tan, Giovanni De Santis, Yara Yakoub, Burak Arslan, Hanna Huber, Ilaria Pola, Lana Grötschel, Guglielmo Di Molfetta, Håvard K. Skjellegrind, Geir Selbaek, Nicholas J. Ashton

Source: Nature
Nature 650(8100), 182-186 (2026). doi:10.1038/s41586-025-09841-y

Subject Terms: Male, Alzheimer Disease: diagnosis, General Science & Technology, BIOMARKERS, tau Proteins, Alzheimer Disease: blood, Article, Cohort Studies, Alzheimer Disease: pathology, Alzheimer Disease, Biomarkers: blood, Cognitive Dysfunction: pathology, Prevalence, Humans, Cognitive Dysfunction, Alzheimer Disease: epidemiology, Phosphorylation, Aged, RISK, Aged, 80 and over, Science & Technology, tau Proteins: blood, Norway, DEMENTIA, tau Proteins: chemistry, Age Factors, Middle Aged, Cognitive Dysfunction: epidemiology, Multidisciplinary Sciences, Cognitive Dysfunction: blood, Science & Technology - Other Topics, Female, Norway: epidemiology, Biomarkers

Access URL: https://pubmed.ncbi.nlm.nih.gov/41407852
https://pubmed.ncbi.nlm.nih.gov/41407852/
https://doi.org/10.1038/s41586-025-09841-y
https://pmc.ncbi.nlm.nih.gov/articles/PMC12872468/
https://pub.dzne.de/record/285022

Associations of lifestyle factors with amyloid pathology in persons without dementia

Authors: Oomens, Julie E, Vos, Stephanie Jb, Gill, Kiran Dip, Yi, Dahyun, Zettergren, Anna, Initiative, Alzheimer's Disease Neuroimaging, group, A4 Study, Network, Dominantly Inherited Alzheimer, Dementia, European Prevention of Alzheimer's, Disease, Prediction of Alzheimer's, Disease, Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's, Ossenkoppele, Rik, Grimmer, Timo, Verhey, Frans Rj, Visser, Pieter Jelle, Jansen, Willemijn J, Early Diagnosis, Hort, Jakub, Itoh, Yoshiaki, Iwatsubo, Takeshi, Klimkowicz-Mrowiec, Aleksandra, Landau, Susan M, Lee, Dong Young, Lleó, Alberto, Martinez-Lage, Pablo, Maserejian, Nancy N, de Mendonça, Alexandre, Meyer, Philipp T, Parchi, Piero, Pardini, Matteo, Parnetti, Lucilla, Popp, Julius, Rami, Lorena, Reiman, Eric M, Rinne, Juha O, Rodrigue, Karen M, Boada, Mercè, Sánchez-Juan, Pascual, Santana, Isabel, Scarmeas, Nikolaos, Scheltens, Philip, Skoog, Ingmar, Sperling, Reisa A, Stern, Yaakov, Villeneuve, Sylvia, Waldemar, Gunhild, Wiltfang, Jens, Didic, Mira, Zetterberg, Henrik, Alcolea, Daniel, Allegri, Ricardo F, Altomare, Daniele, Bateman, Randall J, Baiardi, Simone, Baldeiras, Ines, Blennow, Kaj, Braber, Anouk den, van Buchem, Mark A, Engelborghs, Sebastiaan, Byun, Min Soo, Cerman, Jiří, Chen, Kewei, Chipi, Elena, Day, Gregory S, Drzezga, Alexander, Ekblad, Laura L, Förster, Stefan, Fortea, Juan, Freund-Levi, Yvonne, Fladby, Tormod, Frings, Lars, Guedj, Eric, Habeck, Christian G, Handels, Ron, Hausner, Lucrezia, Hellwig, Sabine, Jiménez-Bonilla, Julio F, Juaristi, Ane Iriondo, Kandimalla, Ramesh, Kern, Silke, van der Flier, Wiesje M, Bordewick Kirsebom, Bjørn-Eivind S, Kornhuber, Johannes, Legdeur, Nienke, Levin, Johannes, Maier, Wolfgang, Marquié, Marta, Minatani, Shinobu, Morbelli, Silvia Daniela, Mroczko, Barbara, Ntanasi, Eva, Frisoni, Giovanni B, de Oliveira, Catarina Resende, Orellana, Adelina, Peters, Oliver, Prabhakar, Sudesh, Ramakers, Inez H, Rodríguez-Rodriguez, Eloy, Ruiz, Agustín, Rüther, Eckart, Sakhardande, Jayant, Selnes, Per, Fröhlich, Lutz, Silva, Dina, Soininen, Hilkka, Spiru, Luiza, Takeda, Akitoshi, Teunissen, Charlotte E, Tijms, Betty M, Vermunt, Lisa, Wallin, Åsa K, Wiels, Wietse, Yannakoulia, Mary

Contributors: Japan Alzheimer's Disease Neuroimaging Initiative , Korean Brain Aging Study, Oomens, Julie E, Vos, Stephanie JB, Maserejian, Nancy N, Boada, Mercè, Didic, Mira, Engelborghs, Sebastiaan, Fladby, Tormod, van der Flier, Wiesje M, Frisoni, Giovanni B, Fröhlich, Lutz, Gill, Kiran Dip, Grimmer, Timo, Hort, Jakub, Itoh, Yoshiaki, Iwatsubo, Takeshi, Klimkowicz-Mrowiec, Aleksandra, Landau, Susan M, Lee, Dong Young, Lleó, Alberto, Martinez-Lage, Pablo, Jansen, Willemijn J, Alzheimer's Disease Neuroimaging Initiative (ADNI), A4 Study group, Dominantly Inherited Alzheimer Network (DIAN), European Prevention of Alzheimer's Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI), Japan Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE), Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) research group, ADNI, A4 Study Group, DIAN, EPAD Consortium, FACEHBI, J-ADNI, Korean Brain Aging Study Early Diag Prediction Alzheimers Dis KBASE, PREVENT-AD Res Group

Source: J Alzheimers Dis
Journal of Alzheimer's disease 108(3), 1043-1059 (2025). doi:10.1177/13872877251379083
Journal of Alzheimer's disease
Oomens, J E, Vos, S JB, Maserejian, N N, Boada, M, Didic, M, Engelborghs, S, Fladby, T, van der Flier, W M, Frisoni, G B, Fröhlich, L, Gill, K D, Grimmer, T, Hort, J, Itoh, Y, Iwatsubo, T, Klimkowicz-Mrowiec, A, Landau, S M, Lee, D Y, Lleó, A, Martinez-Lage, P, de Mendonça, A, Meyer, P T, Parchi, P, Pardini, M, Parnetti, L, Popp, J, Rami, L, Reiman, E M, Rinne, J O, Rodrigue, K M, Sánchez-Juan, P, Santana, I, Scarmeas, N, Scheltens, P, Skoog, I, Sperling, R A, Stern, Y, Villeneuve, S, Waldemar, G, Wiltfang, J, Zetterberg, H, Alcolea, D, Allegri, R F, Altomare, D, Bateman, R J, Baiardi, S, Baldeiras, I, Blennow, K, Braber, A D, van Buchem, M A, Byun, M S, Cerman, J, Chen, K, Chipi, E, Day, G S, Drzezga, A, Ekblad, L L, Förster, S, Fortea, J, Freund-Levi, Y, Frings, L, Guedj, E, Habeck, C G, Handels, R, Hausner, L, Hellwig, S, Jiménez-Bonilla, J F, Juaristi, A I, Kandimalla, R, Kern, S, Bordewick Kirsebom, B-E S, Kornhuber, J, Legdeur, N, Levin, J, Maier, W, Marquié, M, Minatani, S, Morbelli, S D, Mroczko, B, Ntanasi, E, de Oliveira, C R, Orellana, A, Peters, O, Prabhakar, S, Ramakers, I H, Rodríguez-Rodriguez, E, Ruiz, A, Rüther, E, Sakhardande, J, Selnes, P, Silva, D, Soininen, H, Spiru, L, Takeda, A, Teunissen, C E, Tijms, B M, Vermunt, L, Wallin, Å K, Wiels, W, Yannakoulia, M, Yi, D, Zettergren, A, Ossenkoppele, R, Verhey, F RJ, Visser, P J & Jansen, W J 2025, ' Associations of lifestyle factors with amyloid pathology in persons without dementia ', Journal of Alzheimer's Disease, vol. 108, no. 3, pp. 1043-1059 . https://doi.org/10.1177/13872877251379083

Subject Terms: Male, lifestyle, Amyloid, positron emission tomography, Alzheimer's disease, amyloid, amyloid biomarker study, cerebrospinal fluid, Alcohol Drinking, Apolipoprotein E4, Cognitive Dysfunction: genetics, Cognitive Dysfunction: pathology, Humans, Cognitive Dysfunction, Life Style, Research Articles, Aged, Apolipoprotein E4: genetics, Aged, 80 and over, Smoking, Middle Aged, Cognitive Dysfunction: metabolism, Cognitive Dysfunction: psychology, Cross-Sectional Studies, Amyloid: metabolism, Female, Dementia, Human medicine

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/41234025
https://pmc.ncbi.nlm.nih.gov/articles/PMC12647378/
https://pubmed.ncbi.nlm.nih.gov/41234025/
https://doi.org/10.1177/13872877251379083
https://cris.maastrichtuniversity.nl/en/publications/07506ae3-5f6e-447d-bc46-59d32f86de93
https://doi.org/10.1177/13872877251379083
https://pub.dzne.de/record/282559
https://pure.amsterdamumc.nl/en/publications/ff2f4aa1-b4ac-4f16-904c-3545c836faf0
https://doi.org/10.1177/13872877251379083
https://resolver.sub.uni-goettingen.de/purl?gro-2/152983
https://hdl.handle.net/10067/2198950151162165141
https://repository.uantwerpen.be/docstore/d:irua:33115
https://curis.ku.dk/ws/files/523817562/13872877251379083.pdf
https://doi.org/10.1177/13872877251379083
https://researchprofiles.ku.dk/da/publications/c990a9f6-1554-4856-afbe-03dbab642fb1
https://ruj.uj.edu.pl/handle/item/565550
https://journals.sagepub.com/doi/10.1177/13872877251379083
https://hdl.handle.net/11585/1039114
https://doi.org/10.1177/13872877251379083
https://journals.sagepub.com/doi/10.1177/13872877251379083
https://epub.ub.uni-muenchen.de/130542/

Associations between digital speech features of automated cognitive tasks and trajectories of brain atrophy and cognitive decline in early Alzheimer's disease

Authors: Qingyue Li, Stefanie Koehler, Alexandra Koenig, Martin Dyrba, Elisa Mallik, Nicklas Linz, Josef Priller, Eike Spruth, Slawek Altenstein, Jens Wiltfang, Inga Zerr, Claudia Bartels, Franziska Maier, Ayda Rostamzadeh, Emrah Duezel, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Christoph Laske, Sebastian Sodenkamp, Matthias HJ Munk, Bjoern Falkenburger, Antje Osterrath, Ingo Kilimann, Melina Stark, Luca Kleineidam, Michael T Heneka, Annika Spottke, Michael Wagner, Frank Jessen, Gabor C Petzold, Fedor Levin, Stefan Teipel

Contributors: Li, Qingyue, Koehler, Stefanie, Koenig, Alexandra, Dyrba, Martin, Mallik, Elisa, Linz, Nicklas, Priller, Josef, Spruth, Eike, Altenstein, Slawek, Wiltfang, Jens, Zerr, Inga, Bartels, Claudia, Maier, Franziska, Rostamzadeh, Ayda, Duezel, Emrah, Glanz, Wenzel, Incesoy, Enise I, Butryn, Michaela, Laske, Christoph, Sodenkamp, Sebastian, Teipel, Stefan

Source: J Alzheimers Dis
Journal of Alzheimer's disease 107(1), 154-169 (2025). doi:10.1177/13872877251359967
Li, Q, Koehler, S, Koenig, A, Dyrba, M, Mallik, E, Linz, N, Priller, J, Spruth, E, Altenstein, S, Wiltfang, J, Zerr, I, Bartels, C, Maier, F, Rostamzadeh, A, Duezel, E, Glanz, W, Incesoy, E I, Butryn, M, Laske, C, Sodenkamp, S, Munk, M H, Falkenburger, B, Osterrath, A, Kilimann, I, Stark, M, Kleineidam, L, Heneka, M T, Spottke, A, Wagner, M, Jessen, F, Petzold, G C, Levin, F & Teipel, S 2025, 'Associations between digital speech features of automated cognitive tasks and trajectories of brain atrophy and cognitive decline in early Alzheimer's disease', Journal of Alzheimer's disease : JAD, vol. 107, no. 1, pp. 154-169. https://doi.org/10.1177/13872877251359967

Subject Terms: cognition, Male, speech, Neuropsychological Tests, Speech/physiology, Speech: physiology, Alzheimer Disease: psychology, Alzheimer Disease: pathology, Cognition, Alzheimer Disease/psychology, atrophy, Alzheimer Disease, Cognitive Dysfunction/psychology, Cognitive Dysfunction: pathology, Humans, Speech, Brain/pathology, Cognitive Dysfunction, Longitudinal Studies, Atrophy: pathology, natural language processing, Brain: diagnostic imaging, Alzheimer Disease: diagnostic imaging, Cognition/physiology, Research Articles, Aged, Aged, 80 and over, Brain, Cognitive Dysfunction: diagnostic imaging, Alzheimer's disease, Middle Aged, cognitive decline, Magnetic Resonance Imaging, Atrophy/pathology, Brain: pathology, Cognitive Dysfunction: psychology, Cross-Sectional Studies, Disease Progression, Female, Atrophy, Cognition: physiology, early diagnosis

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40685619
https://pub.dzne.de/record/280957
https://resolver.sub.uni-goettingen.de/purl?gro-2/150513
https://hdl.handle.net/20.500.11820/dec3bc8d-d7b6-4475-838f-093fd0472a7c
https://doi.org/10.1177/13872877251359967
https://www.research.ed.ac.uk/en/publications/dec3bc8d-d7b6-4475-838f-093fd0472a7c
https://www.pure.ed.ac.uk/ws/files/585317495/li-et-al-2025-associations-between-digital-speech-features-of-automated-cognitive-tasks-and-trajectories-of-brain.pdf

Predictors of Cognitive Decline in Individuals with Subjective Cognitive Decline of the DELCODE Study Cohort

Authors: Sannemann, Lena, Buerger, Katharina, Hellmann‐Regen, Julian, Kleineidam, Luca, Laske, Christoph, Perneczky, Robert, Peters, Oliver, Priller, Josef, Ramirez, Alfredo, Schneider, Anja, Spottke, Annika, Synofzik, Matthis, Teipel, Stefan J., Wagner, Michael, Wiltfang, Jens, Yakupov, Renat, Düzel, Emrah, Jessen, Frank, the DELCODE Study Group

Contributors: Sannemann, Lena, Buerger, Katharina, Hellmann‐Regen, Julian, Kleineidam, Luca, Laske, Christoph, Perneczky, Robert, Peters, Oliver, Priller, Josef, Ramirez, Alfredo, Schneider, Anja, Spottke, Annika, Synofzik, Matthis, Teipel, Stefan J., Wagner, Michael, Wiltfang, Jens, Yakupov, Renat, Düzel, Emrah, Jessen, Frank, the DELCODE Study Group

Source: Alzheimers Dement
Alzheimer's and dementia 21(Suppl 3), e105570 (2025). doi:10.1002/alz70857_105570
Alzheimer’s Association International Conference, AAIC 25, Toronto, Canada, 2025-07-27-2025-07-31

Subject Terms: Male, Aged, 80 and over, Apolipoprotein E4: genetics, tau Proteins: blood, Amyloid beta-Peptides, Cognitive Dysfunction: diagnosis, Apolipoprotein E4, Hippocampus: pathology, tau Proteins, Middle Aged, Peptide Fragments: blood, Peptide Fragments, Cognitive Dysfunction: blood, Cognitive Dysfunction: psychology, Alzheimer Disease, Cognitive Dysfunction: genetics, Cognitive Dysfunction: pathology, Clinical Manifestations, Humans, Amyloid beta-Peptides: blood, Female, Neuropsychological Tests: statistics & numerical data, Longitudinal Studies, Aged

Access URL: https://pub.dzne.de/record/283062
https://resolver.sub.uni-goettingen.de/purl?gro-2/154412
https://resolver.sub.uni-goettingen.de/purl?gro-2/161965

Predicting longitudinal basal forebrain volume in mild cognitive impairment: the role of sex and APOE4 genotype

Authors: Grazia, Alice, Levin, Fedor, Perneczky, Robert, Laske, Christoph, Spottke, Annika, Ramirez, Alfredo, Teipel, Stefan, Jessen, Frank, Wagner, Michael, Peters, Oliver, Priller, Josef, Schneider, Anja, Wiltfang, Jens, Düzel, Emrah, Buerger, Katharina

Source: Alzheimers Dement
Alzheimer's and dementia 21(Suppl 2), e100257 (2025). doi:10.1002/alz70856_100257
Alzheimer’s Association International Conference, AAIC 25, Toronto, Canada, 2025-07-27-2025-07-31

Subject Terms: Male, Apolipoprotein E4: genetics, Genotype, Apolipoprotein E4, Alzheimer Disease: genetics, Cognitive Dysfunction: diagnostic imaging, Middle Aged, Magnetic Resonance Imaging, Sex Factors, Apolipoproteins E, Basal Forebrain: diagnostic imaging, Cognitive Dysfunction: genetics, Apolipoproteins E: genetics, Cognitive Dysfunction: pathology, Basal Forebrain: pathology, Humans, Female, Longitudinal Studies, Atrophy, Biomarkers, Aged

Access URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC12738425/
https://doi.org/10.1002/alz70856_100257
https://pub.dzne.de/record/283061

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged Mice

Authors: Niki Ktena, Dimitrios Spyridakos, Alexandros Georgilis, Ilias Kalafatakis, Efstathia Thomoglou, Angeliki Kolaxi, Vassiliki Nikoletopoulou, Maria Savvaki, Domna Karagogeos

Source: Glia
Glia, vol. 73, no. 7, pp. 1383-1397

Subject Terms: Neurons, Mice, Knockout, Aging, Animals, Autophagy/physiology, Autophagy/genetics, Oligodendroglia/pathology, Oligodendroglia/ultrastructure, Oligodendroglia/metabolism, Apoptosis/physiology, Apoptosis/genetics, Aging/pathology, Myelin Sheath/pathology, Myelin Sheath/metabolism, Myelin Sheath/ultrastructure, Mice, Transgenic, Neurons/pathology, Neurons/ultrastructure, Mice, Cognitive Dysfunction/pathology, Autophagy-Related Protein 5/genetics, Autophagy-Related Protein 5/metabolism, Mice, Inbred C57BL, Axons/pathology, CNS, aging, autophagy, myelin, neurodegeneration, Apoptosis, Axons, Autophagy-Related Protein 5, Oligodendroglia, Autophagy, Cognitive Dysfunction, Myelin Sheath, Research Article

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40105013
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F62650869ECC7
https://serval.unil.ch/resource/serval:BIB_F62650869ECC.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_F62650869ECC

Inflammasome adaptor ASC promotes sustained neuroinflammation and mild cognitive impairment in a closed-head injury model

Authors: Li, Tao, Castro-Gomez, Mario Sergio, Latz, Eicke, Heneka, Michael T, Botella Lucena, Pablo, Vieira-Saecker, Ana, Schwartz, Stephanie, Ding, Yingying, Deng, Yushuang, Gou, Maling, Stein, Valentin, Golenbock, Douglas T

Source: J Clin Invest
The journal of clinical investigation 136(7), e199818 (2026). doi:10.1172/JCI199818

Subject Terms: Male, Inflammasomes, CARD Signaling Adaptor Proteins: genetics, Mice, Neuroinflammatory Diseases: etiology, Cognitive Dysfunction: genetics, Microglia: metabolism, Cognitive Dysfunction: pathology, Animals, Cognitive Dysfunction: etiology, Neuroinflammatory Diseases: metabolism, Transcriptomics, Mice, Knockout, Inflammation, Innate immunity, Inflammasomes: genetics, Brain Concussion: metabolism, Neuroinflammatory Diseases: pathology, Neuroinflammatory Diseases: genetics, Inflammasomes: metabolism, Brain Concussion: genetics, Cognitive Dysfunction: metabolism, Mice, Inbred C57BL, CARD Signaling Adaptor Proteins, Disease Models, Animal, Pycard protein, mouse, CARD Signaling Adaptor Proteins: metabolism, Brain Concussion: pathology, Dementia, Microglia: pathology, Neuroscience, Research Article

Access URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC13038205/
https://doi.org/10.1172/JCI199818
https://pubmed.ncbi.nlm.nih.gov/41734021/
https://pub.dzne.de/record/285815

Association between basal forebrain volume and age in the presenilin‐1 E280A autosomal dominant Alzheimer's disease kindred

Authors: He, Bing, Ospina Lopera, Paula, Tristão-Pereira, Catarina, Rowe, Meredith C, Giudicessi, Averi, Su, Yi, Chen, Yinghua, Do Carmo, Sonia, Aguillón, David, Cuello, A Claudio, Quiroz, Yakeel T, Espinosa, Alejandro, Becerra, Juan Camilo, Osorio, Laura, Alzate, Diana, Alvarez, Sergio, Grazia, Alice, Teipel, Stefan J, Malotaux, Vincent

Source: Alzheimers Dement
Alzheimer's and dementia 22(1), e71052 (2026). doi:10.1002/alz.71052

Subject Terms: Male, Adult, Basal Forebrain, Alzheimer Disease: genetics, brain volume, Neuropsychological Tests, Colombia, autosomal dominant Alzheimer's disease, memory, PSEN1 protein, human, Alzheimer Disease: pathology, Basal Forebrain: diagnostic imaging, Alzheimer Disease, Cognitive Dysfunction: genetics, presenilin 1, Cognitive Dysfunction: pathology, Presenilin-1, Humans, Cognitive Dysfunction, Alzheimer Disease: diagnostic imaging, basal forebrain, Aged, Middle Aged, Magnetic Resonance Imaging, Basal Forebrain: pathology, Female, Presenilin-1: genetics, Research Article

Access URL: https://pubmed.ncbi.nlm.nih.gov/41476026
https://pmc.ncbi.nlm.nih.gov/articles/PMC12756048/
https://doi.org/10.1002/alz.71052
https://pubmed.ncbi.nlm.nih.gov/41476026/
https://pub.dzne.de/record/283105

A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings

Authors: Baumeister, H., Vogel, J.W., Insel, P.S., Kleineidam, L., Wolfsgruber, S., Stark, M., Gellersen, H.M., Yakupov, R., Schmid, M.C., Lüsebrink, F., Brosseron, F., Ziegler, G., Freiesleben, S.D., Preis, L., Schneider, L.-S., Spruth, E.J., Altenstein, S., Lohse, A., Fliessbach, K., Vogt, I.R., Bartels, C., Schott, B.H., Rostamzadeh, A., Glanz, W., Incesoy, E.I., Butryn, M., Janowitz, D., Rauchmann, B.-S., Kilimann, I., Goerss, D., Munk, M.H., Hetzer, S., Dechent, P., Ewers, M., Scheffler, K., Wuestefeld, A., Strandberg, O., van Westen, D., Mattsson-Carlgren, N., Janelidze, S., Stomrud, E., Palmqvist, S., Spottke, A., Laske, C., Teipel, S., Perneczky, R., Buerger, K., Schneider, A., Priller, J., Peters, O., Ramirez, A., Wiltfang, J., Heneka, M.T., Wagner, M., Düzel, E., Jessen, F., Hansson, O., Berron, D.

Contributors: Baumeister, Hannah, Vogel, Jacob W, Insel, Philip S, Kleineidam, Luca, Wolfsgruber, Steffen, Stark, Melina, Gellersen, Helena M, Yakupov, Renat, Schmid, Matthias C, Lüsebrink, Falk, Berron, David

Source: Brain
Brain 147(7), 2400-2413 (2024). doi:10.1093/brain/awae118
Brain: a Journal of Neurology, 147 (7), 2400-2413 (2024-07-05)
Baumeister, H, Vogel, J W, Insel, P S, Kleineidam, L, Wolfsgruber, S, Stark, M, Gellersen, H M, Yakupov, R, Schmid, M C, Lüsebrink, F, Brosseron, F, Ziegler, G, Freiesleben, S D, Preis, L, Schneider, L-S, Spruth, E J, Altenstein, S, Lohse, A, Fliessbach, K, Vogt, I R, Bartels, C, Schott, B H, Rostamzadeh, A, Glanz, W, Incesoy, E I, Butryn, M, Janowitz, D, Rauchmann, B-S, Kilimann, I, Goerss, D, Munk, M H, Hetzer, S, Dechent, P, Ewers, M, Scheffler, K, Wuestefeld, A, Strandberg, O, van Westen, D, Mattsson-Carlgren, N, Janelidze, S, Stomrud, E, Palmqvist, S, Spottke, A, Laske, C, Teipel, S, Perneczky, R, Buerger, K, Schneider, A, Priller, J, Peters, O, Ramirez, A, Wiltfang, J, Heneka, M T, Wagner, M, Düzel, E, Jessen, F, Hansson, O & Berron, D 2024, 'A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings', Brain. https://doi.org/10.1093/brain/awae118

Subject Terms: Male, Neuropsychological Tests, Magnetic Resonance Imaging/methods, Cohort Studies, Alzheimer Disease/pathology, 80 and over, Human health sciences, Atrophy: pathology, Memory Disorders: pathology, Aged, 80 and over, Cognitive Dysfunction/pathology, Brain, episodic memory, Middle Aged, 16. Peace & justice, Magnetic Resonance Imaging, 3. Good health, Neurology, Disease Progression, Original Article, Female, Episodic, Alzheimer's disease, Memory, Episodic, Magnetic Resonance Imaging: methods, Sciences de la santé humaine, Alzheimer Disease: pathology, Memory, Alzheimer Disease, Neurologie, Cognitive Dysfunction: pathology, Humans, Brain/pathology, Cognitive Dysfunction, Brain: diagnostic imaging, structural MRI, Aged, Memory Disorders, Memory Disorders/pathology, Brain/diagnostic imaging, disease heterogeneity, Atrophy/pathology, Brain: pathology, executive function, Neurology (clinical), Atrophy

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38654513
https://pub.dzne.de/record/270648
https://resolver.sub.uni-goettingen.de/purl?gro-2/143171
https://orbilu.uni.lu/bitstream/10993/67425/1/awae118.pdf
https://orbilu.uni.lu/handle/10993/67425
https://www.research.ed.ac.uk/en/publications/1ee16ed2-822d-435d-a9f2-6fc4c3fc2040
https://www.pure.ed.ac.uk/ws/files/446371555/awae118.pdf
https://www.pure.ed.ac.uk/ws/files/453867169/awae118.pdf
https://hdl.handle.net/20.500.11820/1ee16ed2-822d-435d-a9f2-6fc4c3fc2040
https://doi.org/10.1093/brain/awae118
https://epub.ub.uni-muenchen.de/117816/
https://eprints.whiterose.ac.uk/id/eprint/216745/
https://publications-affiliated.scilifelab.se/publication/ca4e877fc2674394b71d586581237b4d

Unveiling the hippocampal subfield changes across the Alzheimer’s disease continuum: a systematic review of neuroimaging studies

Authors: Alessandro Zilioli, Beatrice Pancaldi, Hannah Baumeister, Gabriele Busi, Francesco Misirocchi, Carlotta Mutti, Irene Florindo, Nicola Morelli, Rosaleena Mohanty, David Berron, Eric Westman, Marco Spallazzi

Source: Brain imaging and behavior 19(1), 253-267 (2025). doi:10.1007/s11682-024-00952-0

Subject Terms: Neuroimaging: methods, Magnetic Resonance Imaging: methods, Hippocampus: pathology, Alzheimer's disease continuum, Neuroimaging, Cognitive Dysfunction: diagnostic imaging, Hippocampal subfields, Hippocampus, Magnetic Resonance Imaging, Alzheimer Disease: pathology, Hippocampus: diagnostic imaging, Alzheimer Disease, Cognitive Dysfunction: pathology, Disease Progression, Humans, Cognitive Dysfunction, Hippocampal volume and surface, Atrophy, Alzheimer Disease: diagnostic imaging

Access URL: https://pubmed.ncbi.nlm.nih.gov/39443362
https://pub.dzne.de/record/276821

Disease stage-specific atrophy markers in Alzheimer’s disease

Authors: Baumeister, Hannah, Gellersen, Helena M, Roeske, Sandra, Marcos Morgado, Barbara, Esselmann, Hermann, Brosseron, Frederic, Ramirez, Alfredo, Lüsebrink, Falk, Synofzik, Matthis, Schott, Björn H, Schmid, Matthias C, Hetzer, Stefan, Polk, Sarah E, Dechent, Peter, Scheffler, Klaus, Ewers, Michael, Hellmann-Regen, Julian, Ersözlü, Ersin, Spruth, Eike Jakob, Gemenetzi, Maria, Fliessbach, Klaus, Bartels, Claudia, Rostamzadeh, Ayda, Lattmann, René, Glanz, Wenzel, Incesoy, Enise I, Janowitz, Daniel, Rauchmann, Boris Stephan, Kilimann, Ingo, Sodenkamp, Sebastian, Coenjaerts, Marie, Spottke, Annika, Peters, Oliver, Priller, Josef, Wuestefeld, Anika, Schneider, Anja, Wiltfang, Jens, Buerger, Katharina, Perneczky, Robert, Teipel, Stefan, Laske, Christoph, Wagner, Michael, Ziegler, Gabriel, Jessen, Frank, Düzel, Emrah, Wisse, Laura E M, Berron, David, group, DELCODE study, Glenn, Trevor, Yakupov, Renat, Stark, Melina, Kleineidam, Luca

Contributors: Baumeister, Hannah, Gellersen, Helena M., Polk, Sarah E., Lattmann, René, Wuestefeld, Anika, Wisse, Laura E. M., Glenn, Trevor, Yakupov, Renat, Stark, Melina, Kleineidam, Luca, Roeske, Sandra, Morgado, Barbara Marcos, Esselmann, Hermann, Brosseron, Frederic, Ramirez, Alfredo, Lüsebrink, Falk, Synofzik, Matthis, Schott, Björn H., Schmid, Matthias C., Hetzer, Stefan, Berron, David, for the DELCODE study group, the DELCODE study group, Apollo - University of Cambridge Repository

Source: medRxiv
Alzheimers Dement
Alzheimer's and dementia 21(7), e70482 (2025). doi:10.1002/alz.70482
Baumeister, H, Gellersen, H M, Polk, S E, Lattmann, R, Wuestefeld, A, Wisse, L E M, Glenn, T, Yakupov, R, Stark, M, Kleineidam, L, Roeske, S, Morgado, B M, Esselmann, H, Brosseron, F, Ramirez, A, Lüsebrink, F, Synofzik, M, Schott, B H, Schmid, M C, Hetzer, S, Dechent, P, Scheffler, K, Ewers, M, Hellmann-Regen, J, Ersözlü, E, Spruth, E, Gemenetzi, M, Fliessbach, K, Bartels, C, Rostamzadeh, A, Glanz, W, Incesoy, E I, Janowitz, D, Rauchmann, B-S, Kilimann, I, Sodenkamp, S, Coenjaerts, M, Spottke, A, Peters, O, Priller, J, Schneider, A, Wiltfang, J, Buerger, K, Perneczky, R, Teipel, S, Laske, C, Wagner, M, Ziegler, G, Jessen, F, Düzel, E, Berron, D 2025, 'Disease stage-specific atrophy markers in Alzheimer's disease', Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 21, no. 7, pp. e70482. https://doi.org/10.1002/alz.70482

Subject Terms: Male, Neuropsychological Tests, Hippocampus, Article, Alzheimer Disease: pathology, Alzheimer Disease, Alzheimer Disease/pathology, Cognitive Dysfunction: pathology, Hippocampus/pathology, imaging biomarker, magnetic resonance imaging, Humans, Brain/pathology, Cognitive Dysfunction, Atrophy: pathology, Brain: diagnostic imaging, Alzheimer Disease: diagnostic imaging, Aged, Aged, 80 and over, Amyloid beta-Peptides, Topic 3: Integrative Biomedicine, parietal lobe, Cognitive Dysfunction/pathology, Hippocampus: pathology, Brain, Cognitive Dysfunction: diagnostic imaging, Magnetic Resonance Imaging, Atrophy/pathology, medial temporal lobe, Brain: pathology, Disease Progression, longitudinal atrophy, Female, Atrophy, Function and Dysfunction of the Nervous System, Biomarkers, Research Article

File Description: application/pdf; text/xml

Access URL: https://pubmed.ncbi.nlm.nih.gov/40691867
https://pubmed.ncbi.nlm.nih.gov/40162264
https://pub.dzne.de/record/280047
https://resolver.sub.uni-goettingen.de/purl?gro-2/150594
https://resolver.sub.uni-goettingen.de/purl?gro-2/148527
https://hdl.handle.net/20.500.11820/f83c2a8b-1d5e-488d-b013-470ff4dba44b
https://doi.org/10.1002/alz.70482
https://www.pure.ed.ac.uk/ws/files/585414768/Alzheimer_s_Dementia_-_2025_-_Baumeister_-_Disease_stage_specific_atrophy_markers_in_Alzheimer_s_disease.pdf
https://www.research.ed.ac.uk/en/publications/f83c2a8b-1d5e-488d-b013-470ff4dba44b
https://eprints.whiterose.ac.uk/id/eprint/229709/

Long-term retrieval performance is associated with CA1 hippocampal volume in older adults and individuals at risk for dementia

Authors: Bartels, Claudia, Tzu-Yueh Chen, Joy, Belz, Michael, Yakupov, Renat, Düzel, Emrah, Glanz, Wenzel, Lüsebrink, Falk, Dechent, Peter, Kleineidam, Luca, Stark, Melina, Spottke, Annika, Coenjaerts, Marie, Fließbach, Klaus, Schneider, Anja, Rostamzadeh, Ayda, Jessen, Frank, H. Schott, Björn, Wiltfang, Jens, Frommann, Ingo, Wagner, Michael, Goya-Maldonado, Roberto

Contributors: Bartels, Claudia, Tzu-Yueh Chen, Joy, Belz, Michael, Yakupov, Renat, Düzel, Emrah, Glanz, Wenzel, Lüsebrink, Falk, Dechent, Peter, Kleineidam, Luca, Stark, Melina, Spottke, Annika, Coenjaerts, Marie, Fließbach, Klaus, Schneider, Anja, Rostamzadeh, Ayda, Jessen, Frank, H. Schott, Björn, Wiltfang, Jens, Frommann, Ingo, Wagner, Michael, Goya-Maldonado, Roberto

Source: Alzheimers Res Ther
Alzheimer's research & therapy 17(1), 195 (2025). doi:10.1186/s13195-025-01833-4

Subject Terms: CA1 Region, Hippocampal: diagnostic imaging, Male, Dementia: diagnostic imaging, Neuropsychological Tests, Hippocampus, Dementia: psychology, Memory, Cognitive Dysfunction: pathology, Humans, Cognitive Dysfunction, Long-term retrieval, CA1 Region, Hippocampal, Aged, Aged, 80 and over, Research, Dementia: pathology, Mental Recall: physiology, Mild cognitive impairment, Organ Size, Cognitive Dysfunction: diagnostic imaging, CA1 Region, Hippocampal: pathology, Magnetic Resonance Imaging, Cognitive Dysfunction: psychology, Mental Recall, Subjective cognitive decline, Female, Dementia, Alzheimer's disease, Consolidation

Access URL: https://pubmed.ncbi.nlm.nih.gov/40847320
https://pmc.ncbi.nlm.nih.gov/articles/PMC12372344/
https://doi.org/10.1186/s13195-025-01833-4
https://pubmed.ncbi.nlm.nih.gov/40847320/
https://pub.dzne.de/record/280785
https://resolver.sub.uni-goettingen.de/purl?gro-2/150681

Amyloid-beta pathology increases synaptic engulfment by glia in feline cognitive dysfunction syndrome: A naturally occurring model of Alzheimer's disease:Aβ drives synaptic loss in feline dementia

Authors: Mcgeachan, Robert, Ewbank, Lucy, Watt, Meg, Sordo, Lorena, Malbon, Alexandra, Salamat, Khalid, Tzioras, Makis, Catarino De Frias Rodrigues, Joao Miguel, Tulloch, Jane, Houston, Fiona, Gunn-Moore, Danielle, Spires-Jones, Tara

Source: Mcgeachan, R, Ewbank, L, Watt, M, Sordo, L, Malbon, A, Salamat, K, Tzioras, M, Catarino De Frias Rodrigues, J M, Tulloch, J, Houston, F, Gunn-Moore, D & Spires-Jones, T 2025, 'Amyloid-beta pathology increases synaptic engulfment by glia in feline cognitive dysfunction syndrome: A naturally occurring model of Alzheimer's disease : Aβ drives synaptic loss in feline dementia', European Journal of Neuroscience, vol. 62, no. 3, e70180, pp. 1-11. https://doi.org/10.1111/ejn.70180

Subject Terms: Male, Cat Diseases/pathology, Cognitive Dysfunction/pathology, Neuroglia/pathology, Disease Models, Animal, Synapses/pathology, Microglia/pathology, Alzheimer Disease/pathology, Cats, Animals, Brain/pathology, Female, Plaque, Amyloid/pathology, Amyloid beta-Peptides/metabolism

File Description: application/pdf

Access URL: https://www.research.ed.ac.uk/en/publications/02990e0d-777c-4e62-8ff7-c379fe64e163
https://hdl.handle.net/20.500.11820/02990e0d-777c-4e62-8ff7-c379fe64e163
https://www.pure.ed.ac.uk/ws/files/534784603/Eur_J_of_Neuroscience_-_2025_-_McGeachan_-_Amyloid_Beta_Pathology_Increases_Synaptic_Engulfment_by_Glia_in_Feline_Cognitive.pdf

Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis

Authors: Johanna Seitz-Holland, Yasser Alemán-Gómez, Kang Ik K. Cho, Ofer Pasternak, Martine Cleusix, Raoul Jenni, Philipp S. Baumann, Paul Klauser, Philippe Conus, Patric Hagmann, Kim Q. Do, Marek Kubicki, Daniella Dwir

Source: Neuropsychopharmacology
Neuropsychopharmacology, vol. 49, no. 7, pp. 1140-1150

Subject Terms: Male, Adult, 16. Peace & justice, Hippocampus, Magnetic Resonance Imaging, Article, 3. Good health, Young Adult, Humans, Matrix Metalloproteinase 9/blood, Matrix Metalloproteinase 9/metabolism, Hippocampus/diagnostic imaging, Hippocampus/pathology, Female, Psychotic Disorders/diagnostic imaging, Psychotic Disorders/pathology, Psychotic Disorders/physiopathology, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/physiopathology, Cognitive Dysfunction/pathology, Diffusion Magnetic Resonance Imaging, Matrix Metalloproteinase 9, Psychotic Disorders, Cognitive Dysfunction

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38431757
https://serval.unil.ch/notice/serval:BIB_3DD3152D3A91
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3DD3152D3A912
https://serval.unil.ch/resource/serval:BIB_3DD3152D3A91.P001/REF.pdf

Longitudinal trajectories of cognitive reserve in hypometabolic subtypes of Alzheimer's disease

Authors: Levin, Fedor, Grothe, Michel J, Dyrba, Martin, Franzmeier, Nicolai, Teipel, Stefan J, Initiative, Alzheimer’s Disease Neuroimaging

Contributors: Instituto de Salud Carlos III, European Commission, Grothe, Michel J. [0000-0003-2600-9022], Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]

Source: Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Neurobiology of aging 135, 26-38 (2024). doi:10.1016/j.neurobiolaging.2023.12.003

Subject Terms: Subtypes, 2. Zero hunger, Gray Matter: diagnostic imaging, Cognitive reserve, Mild cognitive impairment, Brain, Prodromal AD, 16. Peace & justice, 3. Good health, Brain: pathology, Alzheimer Disease: pathology, Cognition, Cognitive Reserve, Alzheimer Disease, Gray Matter: pathology, Cognitive Dysfunction: pathology, Humans, Cognitive Dysfunction, Gray Matter, Brain: diagnostic imaging, FDG-PET, Alzheimer Disease: diagnostic imaging, Alzheimer's disease

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38157587
http://hdl.handle.net/10261/360516
https://pub.dzne.de/record/267497
https://epub.ub.uni-muenchen.de/117558/

SUSTAINED COGNITIVE DECLINE IN MULTIPLE SCLEROSIS: INVESTIGATING THE ROLE OF WHITE MATTER LESION LOAD USING AN AI-DRIVEN BRAIN IMAGING APPROACH.

Authors: Tota, Vito, Mehuys, Astrid, Vansnick, Tanguy, Amel, Otmane, Chahbar, Fatma, Mahmoudi, Lamia, Mahmoudi, Sidi Ahmed, Briganti, Giovanni, Ris, Laurence, Mahmoudi, Said

Source: Psychiatria Danubina, 37 (Suppl 1), 321 - 329 (2025-09)

Subject Terms: artificial intelligence, cognitive impairment, multiple sclerosis, neuroimaging, white matter lesion load, Humans, Male, Female, Middle Aged, Magnetic Resonance Imaging/methods, Adult, Disease Progression, Brain/diagnostic imaging, Brain/pathology, Multiple Sclerosis/diagnostic imaging, Multiple Sclerosis/complications, Multiple Sclerosis/pathology, White Matter/diagnostic imaging, White Matter/pathology, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/etiology, Cognitive Dysfunction/pathology, Artificial Intelligence, Brain, Cognitive Dysfunction, Magnetic Resonance Imaging, White Matter, Psychiatry and Mental Health, Human health sciences, Neurology, Sciences de la santé humaine, Neurologie

Relation: urn:issn:0353-5053

Access URL: https://orbi.uliege.be/handle/2268/339130

Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease

Authors: Jannis Denecke, Anna Dewenter, Jongho Lee, Nicolai Franzmeier, Carolina Valentim, Anna Kopczak, Martin Dichgans, Lukas Pirpamer, Benno Gesierich, Marco Duering, Michael Ewers

Source: Alzheimers Dement
Alzheimer's and dementia 21(5), e70127 (2025). doi:10.1002/alz.70127

Subject Terms: Male, Myelin Sheath: metabolism, CADASIL, Myelin Sheath: pathology, CADASIL: complications, Neuropsychological Tests, Cerebral Small Vessel Diseases: diagnostic imaging, CADASIL: diagnostic imaging, White Matter: diagnostic imaging, chi separation, Cognitive Dysfunction: pathology, Humans, Cognitive Dysfunction: etiology, Cognitive Dysfunction, Myelin Sheath, diffusion magnetic resonance imaging, Aged, susceptibility mapping, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, Cognitive Dysfunction: diagnostic imaging, white matter hyperintensities, Middle Aged, White Matter, Magnetic Resonance Imaging, Diffusion Tensor Imaging, White Matter: pathology, Cerebral Small Vessel Diseases, Female, CADASIL: pathology, Cerebral Small Vessel Diseases: complications, Research Article

Access URL: https://pubmed.ncbi.nlm.nih.gov/40317599
https://pub.dzne.de/record/278103
https://epub.ub.uni-muenchen.de/126134/

Automated segmentation for cortical thickness of the medial perirhinal cortex

Authors: Henzen, N.A., Abdulkadir, A., Reinhardt, J., Blatow, M., Kressig, R.W., Krumm, S.

Source: Sci Rep
Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)
Scientific reports, vol. 15, no. 1, pp. 14903

Subject Terms: Male, Adult, Science, 616.8: Neurologie und Krankheiten des Nervensystems, 006: Spezielle Computerverfahren, Article, Perirhinal cortex, Alzheimer Disease, Image Processing, Computer-Assisted, Humans, Entorhinal Cortex, Cognitive Dysfunction, Aged, Perirhinal Cortex, Entorhinal cortex, Aged, 80 and over, Female, Alzheimer Disease/pathology, Alzheimer Disease/diagnostic imaging, Magnetic Resonance Imaging/methods, Cognitive Dysfunction/pathology, Cognitive Dysfunction/diagnostic imaging, Perirhinal Cortex/diagnostic imaging, Perirhinal Cortex/pathology, Middle Aged, Entorhinal Cortex/pathology, Entorhinal Cortex/diagnostic imaging, Image Processing, Computer-Assisted/methods, Alzheimer's disease, Deep learning, Semantic segmentation, Structural MRI, Magnetic Resonance Imaging, Medicine

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40295570
https://doaj.org/article/29f97b4e385a410c961e7f3de8d75044
https://serval.unil.ch/notice/serval:BIB_B96D71A9752A
https://serval.unil.ch/resource/serval:BIB_B96D71A9752A.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B96D71A9752A3

Microstructural assessment of the locus coeruleus–entorhinal cortex pathway and association with ATN markers in cognitive impairment

Authors: Aiello, Marco, Marizzoni, Moira, Borrelli, Pasquale, Cavaliere, Carlo, Ribaldi, Federica, Garibotto, Valentina, Scheffler, Max, Jelescu, Ileana O, Jovicich, Jorge, Catani, Marco, Salvatore, Marco, Frisoni, Giovanni B, Pievani, Michela

Source: Alzheimers Dement
Alzheimer's & dementia, vol. 21, no. 4, pp. e70126

Subject Terms: Male, Amyloid beta-Peptides, Humans, Locus Coeruleus/diagnostic imaging, Locus Coeruleus/pathology, Locus Coeruleus/metabolism, Female, Cognitive Dysfunction/pathology, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/metabolism, Cross-Sectional Studies, Aged, Entorhinal Cortex/diagnostic imaging, Entorhinal Cortex/pathology, Entorhinal Cortex/metabolism, Biomarkers/metabolism, tau Proteins/metabolism, Positron-Emission Tomography, Magnetic Resonance Imaging, Neural Pathways/pathology, Neural Pathways/diagnostic imaging, Alzheimer Disease/pathology, Alzheimer Disease/diagnostic imaging, Amyloid beta-Peptides/metabolism, Middle Aged, amyloid/tau/neurodegeneration, dementia, diffusion‐weighted imaging, entorhinal cortex, locus coeruleus, magnetic resonance imaging, tau Proteins, Alzheimer Disease, Neural Pathways, Entorhinal Cortex, Locus Coeruleus, Cognitive Dysfunction, Biomarkers, Research Article

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40289861
https://hdl.handle.net/11564/874059
https://serval.unil.ch/notice/serval:BIB_4C8321F17AD1
https://serval.unil.ch/resource/serval:BIB_4C8321F17AD1.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4C8321F17AD15
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70126
https://hdl.handle.net/11572/471332
https://doi.org/10.1002/alz.70126

Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer’s disease

Authors: Nicolai Franzmeier, Sebastian Niclas Roemer-Cassiano, Alexander Maximilian Bernhardt, Amir Dehsarvi, Anna Dewenter, Anna Steward, Davina Biel, Lukas Frontzkowski, Zeyu Zhu, Johannes Gnörich, Julia Pescoller, Fabian Wagner, Fabian Hirsch, Hannah de Bruin, Rik Ossenkoppele, Carla Palleis, Felix Strübing, Michael Schöll, Johannes Levin, Matthias Brendel, Günter U. Höglinger

Source: Mol Neurodegener
Molecular Neurodegeneration, Vol 20, Iss 1, Pp 1-15 (2025)
Molecular neurodegeneration 20(1), 31 (2025). doi:10.1186/s13024-025-00822-3

Subject Terms: Male, Amyloid, alpha-Synuclein: metabolism, MAPT protein, human, tau Proteins, tau Proteins: metabolism, Alzheimer Disease: pathology, Alzheimer Disease, Cognitive Dysfunction: pathology, Humans, Cognitive Dysfunction, RC346-429, Alzheimer Disease: diagnostic imaging, Aged, Aged, 80 and over, Amyloid beta-Peptides, RC952-954.6, Biomarkers: metabolism, Brain, Amyloid beta-Peptides: metabolism, Middle Aged, Cognitive Dysfunction: metabolism, Brain: pathology, Geriatrics, Positron-Emission Tomography, Amyloid: metabolism, alpha-Synuclein, Biomarkers: cerebrospinal fluid, Female, Alzheimer Disease: metabolism, Neurology. Diseases of the nervous system, Brain: metabolism, Biomarkers, Research Article

Access URL: https://pubmed.ncbi.nlm.nih.gov/40098057
https://doaj.org/article/9db79ea53a6f48a98c72d027c4c0f9e9
https://pub.dzne.de/record/277547
https://pure.amsterdamumc.nl/en/publications/52d64b26-5605-48b5-aa32-94aeefcff944
https://doi.org/10.1186/s13024-025-00822-3
https://epub.ub.uni-muenchen.de/125351/