Impact of prolonged hospitalization and inadequate anticoagulation on cognitive decline in older patients with atrial fibrillation.

Transliterated Title: Impacto de la hospitalización prolongada y de la anticoagulación inadecuada en el deterioro cognitivo del paciente mayor con fibrilación auricular.

Authors: Burgos Bencosme N; Área de gestión clínica de Geriatría, Hospital Monte Naranco, Oviedo, España; Área de gestión clínica de Geriatría, Hospital Universitario Central de Asturias, Oviedo, España; Área de gestión clínica de Neurología, Hospital Universitario Central de Asturias, Oviedo, España. Electronic address: n.burgosbencosme@gmail.com., Herrera Parra JE; Área de gestión clínica de Geriatría, Hospital Monte Naranco, Oviedo, España; Área de gestión clínica de Geriatría, Hospital Universitario Central de Asturias, Oviedo, España., Antuña Montes L; Área de gestión clínica de Geriatría, Hospital Monte Naranco, Oviedo, España; Área de gestión clínica de Geriatría, Hospital Universitario Central de Asturias, Oviedo, España., Rodríguez Santiago SE; Área de gestión clínica de Geriatría, Hospital Monte Naranco, Oviedo, España; Área de gestión clínica de Geriatría, Hospital Universitario Central de Asturias, Oviedo, España., González Delgado M; Área de gestión clínica de Neurología, Hospital Universitario Central de Asturias, Oviedo, España; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, España., Gutiérrez Rodríguez J; Área de gestión clínica de Geriatría, Hospital Monte Naranco, Oviedo, España; Área de gestión clínica de Geriatría, Hospital Universitario Central de Asturias, Oviedo, España; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, España.

Source: Medicina clinica [Med Clin (Barc)] 2026 Aug; Vol. 166 (8), pp. 107515. Date of Electronic Publication: 2026 Jun 28.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Elsevier España Country of Publication: Spain NLM ID: 0376377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1578-8989 (Electronic) Linking ISSN: 00257753 NLM ISO Abbreviation: Med Clin (Barc) Subsets: MEDLINE

MeSH Terms: Atrial Fibrillation*/drug therapy , Atrial Fibrillation*/complications , Anticoagulants*/therapeutic use , Anticoagulants*/administration & dosage , Length of Stay*/statistics & numerical data , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/epidemiology, Humans ; Female ; Aged, 80 and over ; Male ; Retrospective Studies ; Risk Factors ; Prospective Studies ; Hospitalization

The Relationship Between Cognitive Function and Micronutrient Levels in Non-Geriatric Patients with Type 2 Diabetes Mellitus.

Authors: Gokce EC; Department of Internal Medicine, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, Türkiye., Akbas F; Department of Internal Medicine, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, Türkiye., Acar T; Department of Biochemistry, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, Türkiye.

Source: Metabolic syndrome and related disorders [Metab Syndr Relat Disord] 2026 Aug; Vol. 24 (6), pp. 250-257. Date of Electronic Publication: 2026 May 26.

Publication Type: Journal Article

Journal Info: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101150318 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8518 (Electronic) Linking ISSN: 15404196 NLM ISO Abbreviation: Metab Syndr Relat Disord Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/psychology , Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/diagnosis , Cognition*/physiology , Micronutrients*/blood , Cognitive Dysfunction*/blood , Cognitive Dysfunction*/diagnosis, Biomarkers/blood ; Humans ; Female ; Male ; Middle Aged ; Case-Control Studies ; Adult ; Aged ; Young Adult ; Adolescent

High-density lipoprotein cholesterol and cognitive function in patients undergoing hemodialysis.

Authors: Kato K; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Nakashima A; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan. a-nakashima@jikei.ac.jp., Aizawa C; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Kobayashi A; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Shinagawa S; Department of Psychiatry, The Jikei University School of Medicine, Tokyo, Japan., Ohkido I; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Urashima M; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Yokoo T; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Source: Clinical and experimental nephrology [Clin Exp Nephrol] 2026 Aug; Vol. 30 (8), pp. 1237-1244. Date of Electronic Publication: 2026 May 26.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 9709923 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7799 (Electronic) Linking ISSN: 13421751 NLM ISO Abbreviation: Clin Exp Nephrol Subsets: MEDLINE

MeSH Terms: Renal Dialysis*/adverse effects , Cholesterol, HDL*/blood , Cognitive Dysfunction*/blood , Cognitive Dysfunction*/diagnosis , Cognitive Dysfunction*/psychology , Cognitive Dysfunction*/etiology , Cognition*, Biomarkers/blood ; Triglycerides/blood ; Cholesterol, LDL/blood ; Humans ; Female ; Cross-Sectional Studies ; Male ; Aged ; Japan ; Risk Factors ; Aged, 80 and over ; Multivariate Analysis ; Mental Status and Dementia Tests ; Linear Models ; Up-Regulation

Microglial NLRP3-dependent pyroptosis promotes cognitive dysfunction of diabetic encephalopathy by inhibiting adult hippocampal neurogenesis through the release of IL-1β.

Authors: Hua MY; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Huang S; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Zhuang ZY; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China.; Department of Endocrinology and Metabolism, The First People's Hospital of Jinan, Jinan, 250011, China., Han XL; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Liu XJ; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Liang ZH; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Lou NJ; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Zheng FJ; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Lv L; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China., Zhuang XH; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China. zhuangxianghua@email.sdu.edu.cn.; Multidisciplinary Innovation Center for Nephrology of the Second Qilu Hospital of Shandong University, Jinan, 250033, China. zhuangxianghua@email.sdu.edu.cn., Yu SY; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China. shuyanyu@sdu.edu.cn., Chen SH; Department of Endocrinology and Metabolism, The Second Qilu Hospital of Shandong University, Jinan, 250033, China. chenshihong@sdu.edu.cn.; Multidisciplinary Innovation Center for Nephrology of the Second Qilu Hospital of Shandong University, Jinan, 250033, China. chenshihong@sdu.edu.cn.

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Aug; Vol. 47 (8), pp. 2049-2064. Date of Electronic Publication: 2026 Mar 20.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

MeSH Terms: NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Pyroptosis*/physiology , Interleukin-1beta*/metabolism , Microglia*/metabolism , Hippocampus*/metabolism , Hippocampus*/pathology , Neurogenesis*/physiology , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/etiology , Brain Diseases*/metabolism , Diabetes Complications*/metabolism, Caspase 1/metabolism ; Animals ; Mice, Inbred C57BL ; Male ; Mice ; Hypoglycemia

SCR Disease Name: hypoglycemic encephalopathy

Cognitive Rehabilitation After Stroke: A Case Series Testing a New Method to Transfer Gains to Daily Life.

Authors: Uswatte G; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Physical Therapy, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Taub E; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., McKay S; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Mitchell BS; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Blake JA; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Knight A; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Biney F; Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Iosipchuk O; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Mark VW; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Lin C; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA., Zhou X; Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Ball K; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Ophthalmology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Neurobiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.

Source: Restorative neurology and neuroscience [Restor Neurol Neurosci] 2026 Aug; Vol. 44 (3), pp. 360-373. Date of Electronic Publication: 2026 Mar 17.

Publication Type: Journal Article

Journal Info: Publisher: IOS Press Country of Publication: United States NLM ID: 9005499 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3627 (Electronic) Linking ISSN: 09226028 NLM ISO Abbreviation: Restor Neurol Neurosci Subsets: MEDLINE

MeSH Terms: Activities of Daily Living*/psychology , Stroke Rehabilitation*/methods , Stroke*/complications , Stroke*/psychology , Cognitive Dysfunction*/rehabilitation , Cognitive Dysfunction*/etiology , Transfer, Psychology*/physiology , Cognition Disorders*/rehabilitation , Cognition Disorders*/etiology , Cognitive Behavioral Therapy*/methods, Constraint Induced Movement Therapy/methods ; Humans ; Female ; Male ; Cognitive Training ; Aged ; Middle Aged ; Neuropsychological Tests ; Processing Speed ; Pilot Projects ; Treatment Outcome

Psychometric properties of the Dysexecutive Questionnaire (DEX) in individuals with a previous cardiac event.

Authors: Vig A; Department of Psychology, Lund University, Lund, Sweden.; Department of Cognitive Medicine, Ängelholm Hospital, Ängelholm, Sweden., Vestberg S; Department of Psychology, Lund University, Lund, Sweden., Evald L; Hammel Neurorehabilitation Centre and University Research Clinic, Hammel, Denmark., Mion M; Essex Cardiothoracic Centre, Mid and South Essex NHS Foundation Trust, Basildon, UK.; Medical Technology Research Centre, Anglia Ruskin School of Medicine, Chelmsford, UK., Segerström M; Department of Neurology and Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Ullén S; Clinical Studies Sweden - Forum South, Skane University Hospital, Lund, Sweden., Årestedt K; Faculty of Health and Life Sciences, Department of Health and Caring Sciences, Linnaeus University, Kalmar/Växjö, Sweden.; Department of Research, Region Kalmar County, Kalmar, Sweden., Nielsen N; Department of Clinical Sciences Lund, Clinical Sciences Helsingborg, Lund University, Lund, Sweden.; Department of Anesthesiology and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden., Cronberg T; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Neurology, Skane University Hospital, Lund, Sweden., Lilja G; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Neurology, Skane University Hospital, Lund, Sweden., Blennow Nordström E; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Rehabilitation Medicine, Skane University Hospital, Lund, Sweden.

Source: Neuropsychological rehabilitation [Neuropsychol Rehabil] 2026 Aug; Vol. 36 (7), pp. 1365-1385. Date of Electronic Publication: 2025 Nov 27.

Publication Type: Journal Article; Multicenter Study; Observational Study

Journal Info: Publisher: Routledge, Taylor & Francis Group Country of Publication: England NLM ID: 9112672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-0694 (Electronic) Linking ISSN: 09602011 NLM ISO Abbreviation: Neuropsychol Rehabil Subsets: MEDLINE

MeSH Terms: Cognitive Dysfunction*/diagnosis , Cognitive Dysfunction*/etiology , Executive Function*/physiology , Neuropsychological Tests*/standards , Psychometrics*/instrumentation, Aged ; Female ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Surveys and Questionnaires

Programmed cell death 1 pathway and cognitive function in patients undergoing hemodialysis.

Authors: Kato K; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Nakashima A; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Aizawa C; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Hayashi A; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Kobayashi A; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.; Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan., Shinagawa S; Department of Psychiatry, The Jikei University School of Medicine, Tokyo, Japan., Ohkido I; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Urashima M; Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan., Yokoo T; Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Source: Journal of nephrology [J Nephrol] 2026 Jul 31; Vol. 39 (3), pp. 556-563.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Springer Country of Publication: England NLM ID: 9012268 Publication Model: Print Cited Medium: Internet ISSN: 1724-6059 (Electronic) Linking ISSN: 11218428 NLM ISO Abbreviation: J Nephrol Subsets: MEDLINE

MeSH Terms: Renal Dialysis*/adverse effects , Programmed Cell Death 1 Receptor*/blood , B7-H1 Antigen*/blood , Cognitive Dysfunction*/blood , Cognitive Dysfunction*/psychology , Cognitive Dysfunction*/diagnosis , Cognitive Dysfunction*/etiology , Cognition*, Biomarkers/blood ; Humans ; Female ; Male ; Cross-Sectional Studies ; Aged ; Aged, 80 and over ; Risk Factors ; Logistic Models ; Mental Status and Dementia Tests ; Signal Transduction ; Multivariate Analysis

Kushenol E alleviates sepsis-associated cognitive dysfunction via microglial indoleamine 2,3-dioxygenase 1 inhibition.

Authors: Yang Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China., Lin W; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China., Zhuo Y; Department of Anesthesiology, Xiamen Haicang Hospital, Xiamen 361026, China., Yang J; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China., Wei Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China., Pan W; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China., Liao Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China. Electronic address: liaoyanlingfjsl@126.com., Yao Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China. Electronic address: fjslyys@fjmu.edu.cn.

Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jul 25; Vol. 157, pp. 158338. Date of Electronic Publication: 2026 May 25.

Publication Type: Journal Article

Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

MeSH Terms: Indoleamine-Pyrrole 2,3,-Dioxygenase*/antagonists & inhibitors , Indoleamine-Pyrrole 2,3,-Dioxygenase*/metabolism , Microglia*/drug effects , Microglia*/enzymology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/etiology , Sepsis*/complications , Sepsis-Associated Encephalopathy*/drug therapy , Flavonoids*/pharmacology, Oxidative Stress/drug effects ; Kynurenine/metabolism ; Animals ; Male ; Mice, Inbred C57BL ; Mice

Adaptive pathways for multimodal community-based detection of cognitive impairment: the CogScreen I study.

Authors: Kurz C; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Ismaninger Str. 22, 81675, Munich, Germany. carolin.kurz@mri.tum.de.; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany. carolin.kurz@mri.tum.de., Wüsten NC; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Tegethoff P; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Taute M; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Kehrls M; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Hufnagel A; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., de Jonge S; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Deckert A; Davos Alzheimer's Cooperative, Wayne, PA, USA., Suchsland MZ; Davos Alzheimer's Cooperative, Wayne, PA, USA., König A; Ki:Elements GmbH, Saarbrücken, Germany., Feustel E; Johanniter-Unfall-Hilfe E.V., Munich, Germany.; Department of Public Health (Gesundheitsreferat), City of Munich, Munich, Germany., Heindl P; Johanniter-Unfall-Hilfe E.V., Munich, Germany.; Department of Public Health (Gesundheitsreferat), City of Munich, Munich, Germany., Mattke S; The USC Brain Health Observatory, USC Dornsife, Los Angeles, CA, USA., Perneczky R; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College, London, UK.; International Registry for Alzheimer´S Disease and Other Dementias (InRAD) Foundation, Deventer, The Netherlands.

Source: Scientific reports [Sci Rep] 2026 Jul 23; Vol. 16 (1). Date of Electronic Publication: 2026 Jul 23.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Cognitive Dysfunction*/diagnosis , Cognitive Dysfunction*/blood, Biomarkers/blood ; Dementia/diagnosis ; Amyloid beta-Peptides/blood ; Humans ; Female ; Aged ; Male ; Surveys and Questionnaires ; Aged, 80 and over ; Early Diagnosis ; Independent Living

Impact of different degrees of social engagement interventions (DDSEIs) on cognitive performance and brain activity in community-dwelling adults with subjective cognitive decline in Nanjing, China: a randomised controlled trial protocol.

Authors: Li J; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Yang X; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Xu H; Nanjing Medical University Affiliated Geriatric Hospital, Nanjing, Jiangsu, China., Pan W; Suzhou Ruiying Rehabilitation Hospital, Suzhou, Jiangsu, China., Shi C; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Xia N; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Cheng Y; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Meng F; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Li H; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Liu J; Clinical Medicine Research Institution, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, Jiangsu, China., Qi M; Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Wang T; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Reinhardt JD; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China ZhuYi1981@njmu.edu.cn reinhardt@scu.edu.cn.; Institute for Disaster Management and Reconstruction, Sichuan University, Chengdu, China.; Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland., Zhu Y; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China ZhuYi1981@njmu.edu.cn reinhardt@scu.edu.cn.

Source: BMJ open [BMJ Open] 2026 Jul 21; Vol. 16 (7), pp. e108844. Date of Electronic Publication: 2026 Jul 21.

Publication Type: Journal Article; Clinical Trial Protocol

Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

MeSH Terms: Cognitive Dysfunction*/therapy , Cognitive Dysfunction*/psychology , Social Isolation*/psychology , Cognition* , Social Interaction* , Brain*, White Matter/diagnostic imaging ; Humans ; Aged ; China ; Female ; Male ; Middle Aged ; Aged, 80 and over ; Randomized Controlled Trials as Topic ; Independent Living ; Cognitive Training ; Cognitive Enhancement

Isoorientin inhibits oxidative stress to ameliorate cognitive dysfunction in type 2 diabetes mice via GSK3β/Nrf2 axis.

Authors: Tan X; Medical Department, City University of Wuhan, Wuhan, Hubei Province, China. xqtan@wic.edu.cn., Gao Y; Medical Department, City University of Wuhan, Wuhan, Hubei Province, China., Zhang L; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China., He Y; Medical Department, City University of Wuhan, Wuhan, Hubei Province, China., Li QX; Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, Hawaii, USA. qingl@hawaii.edu.; Hawaii Pacific Neuroscience, 2230 Liliha Street, Honolulu, 96817, HI, USA. qingl@hawaii.edu., Dong Y; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. dondy001@gzucm.edu.cn.

Source: Metabolic brain disease [Metab Brain Dis] 2026 Jul 17; Vol. 41 (1). Date of Electronic Publication: 2026 Jul 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE

MeSH Terms: Oxidative Stress*/drug effects , Glycogen Synthase Kinase 3 beta*/metabolism , NF-E2-Related Factor 2*/metabolism , Luteolin*/pharmacology , Luteolin*/therapeutic use , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/complications , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/etiology, Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/drug therapy ; Signal Transduction/drug effects ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Apoptosis/drug effects ; Brain/drug effects ; Brain/metabolism ; Animals ; Mice ; Male ; Mice, Inbred C57BL

The role of astrocytic GSDME in Sepsis-associated cognitive dysfunction.

Authors: Zhao X; Department of Integrative Medicine and Neurobiology, School of Basic Medical Science, State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China; Department of traditional Chinese medicine, Zhangye People's Hospital affiliated to Hexi University, Zhangye 734000, China., Wu X; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Anesthesiology, Shanghai Geriatric Medical Center, Shanghai 201104, China; Shanghai Key laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Sun Q; Department of Integrative Medicine and Neurobiology, School of Basic Medical Science, State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China., Ma B; Department of Integrative Medicine and Neurobiology, School of Basic Medical Science, State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China., Zhang T; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Anesthesiology, Shanghai Geriatric Medical Center, Shanghai 201104, China; Shanghai Key laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Wang D; Department of Integrative Medicine and Neurobiology, School of Basic Medical Science, State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China., Gao S; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Anesthesiology, Shanghai Geriatric Medical Center, Shanghai 201104, China; Shanghai Key laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Jiang Y; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Anesthesiology, Shanghai Geriatric Medical Center, Shanghai 201104, China; Shanghai Key laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Shen R; Shanghai Laboratory Animal Research Center, Shanghai 201203, China. Electronic address: shenruling@slarc.org.cn., Chen W; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Anesthesiology, Shanghai Geriatric Medical Center, Shanghai 201104, China; Shanghai Key laboratory of Perioperative Stress and Protection, Shanghai 200032, China. Electronic address: chenwank@163.com., Wang J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Science, State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China. Electronic address: jwangf@shmu.edu.cn.

Source: International immunopharmacology [Int Immunopharmacol] 2026 Jul 15; Vol. 181, pp. 116736. Date of Electronic Publication: 2026 Apr 28.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: Astrocytes*/metabolism , Astrocytes*/drug effects , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/metabolism , Iridoids*/pharmacology , Iridoids*/therapeutic use , Sepsis*/complications , Sepsis*/drug therapy , Sepsis-Associated Encephalopathy*/drug therapy , Sepsis-Associated Encephalopathy*/metabolism, Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Pyroptosis/drug effects ; Animals ; Male ; Mice ; Mice, Inbred C57BL ; Disease Models, Animal ; Humans

Th17 cell mediated oligodendrocyte precursor cell arrest drives hippocampal demyelination in diabetic cognitive dysfunction.

Authors: Hu JW; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Yu HD; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Yu SX; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Liu WQ; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Wang YF; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Wang YL; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Chen XY; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Miao QL; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Yuan YR; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Dai W; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Liu MR; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Zhang N; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Sui JH; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Liu XZ; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China., Shan W; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China., Zuo ZF; Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, PR China.; Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou 121001, PR China.

Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2026 Jul 15; Vol. 140 (7), pp. 1521-1534.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

MeSH Terms: Hippocampus*/metabolism , Hippocampus*/pathology , Hippocampus*/immunology , Oligodendrocyte Precursor Cells*/metabolism , Oligodendrocyte Precursor Cells*/immunology , Oligodendrocyte Precursor Cells*/pathology , Th17 Cells*/metabolism , Th17 Cells*/immunology , Demyelinating Diseases*/metabolism , Demyelinating Diseases*/pathology , Demyelinating Diseases*/immunology , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/immunology , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/pathology , Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/immunology , Diabetes Mellitus, Experimental*/chemically induced, Interleukin-17/metabolism ; Interleukin-17/immunology ; Animals ; Male ; Mice, Inbred C57BL ; Mice ; Cognition

Exploring the Relationship Between Hearing Loss and Cognitive Dysfunction from the Perspective of Molecular Mechanisms.

Authors: Wang L; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China., Zhou Z; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China., Shen X; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China., Wu G; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China., Chen X; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China., Liu B; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China., Xiao H; Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Clinical Medical Research Center of Deafness and Vertigo in Hubei Province, Wuhan 430022, China.

Source: Biomolecules [Biomolecules] 2026 Jul 04; Vol. 16 (7). Date of Electronic Publication: 2026 Jul 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH Terms: Hearing Loss*/metabolism , Hearing Loss*/complications , Hearing Loss*/pathology , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/complications , Cognitive Dysfunction*/pathology, tau Proteins/metabolism ; Amyloid beta-Peptides/metabolism ; Reactive Oxygen Species/metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; gamma-Aminobutyric Acid/metabolism ; Glutamic Acid/metabolism ; Humans ; Animals

Icariin Alleviates Diabetes-Associated Cognitive Dysfunction Through Modulation of LCN2-MEK/ERK Signaling-Associated Neuroinflammation.

Authors: Jiao X; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Ren Y; Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Yu Z; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Zhou J; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Wang D; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Yan B; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Tian G; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2026 Jul; Vol. 32 (7), pp. e71008.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

MeSH Terms: Flavonoids*/pharmacology , Flavonoids*/therapeutic use , Neuroinflammatory Diseases*/drug therapy , Neuroinflammatory Diseases*/metabolism , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/physiology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/etiology , Lipocalin-2*/metabolism, Hippocampus/drug effects ; Hippocampus/metabolism ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/complications ; Animals ; Mice ; Male ; Mice, Inbred C57BL ; Humans

LncRNA MIAT Protects Against Sevoflurane-Induced Cognitive Dysfunction in Neonatal Rats via the miR-15b-5p/Ccnd1 Axis.

Authors: Lu X; Anesthesiology Department, Zhongda Hospital (Jiangbei), Southeast University, Nanjing, Jiangsu, China., He X; Anesthesiology Department, First Affiliated Hospital of Kunming Medical University, Kunming, China., Zhan Z; Anesthesiology Department, The First Hospital of Putian City, Putian, China., Chen H; Anesthesiology Department, The First Hospital of Putian City, Putian, China., Chen J; Department of Cardiovascular Medicine, The First Hospital of Putian City, Putian, China., Fan Z; Department of Anesthesiology, Caidian District People's Hospital of Wuhan, Wuhan, China.

Source: Synapse (New York, N.Y.) [Synapse] 2026 Jul; Vol. 80 (4), pp. e70050.

Publication Type: Journal Article

Journal Info: Publisher: Country of Publication: United States NLM ID: 8806914 Publication Model: Print Cited Medium: Internet ISSN: 1098-2396 (Electronic) Linking ISSN: 08874476 NLM ISO Abbreviation: Synapse Subsets: MEDLINE

MeSH Terms: Sevoflurane*/toxicity , MicroRNAs*/metabolism , MicroRNAs*/genetics , RNA, Long Noncoding*/metabolism , RNA, Long Noncoding*/genetics , Cyclin D1*/metabolism , Cyclin D1*/genetics , Cognitive Dysfunction*/chemically induced , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/prevention & control , Anesthetics, Inhalation*/toxicity, Hippocampus/metabolism ; Hippocampus/drug effects ; Animals ; Rats, Sprague-Dawley ; Animals, Newborn ; Rats ; Male

Amygdala microstructural changes in subjective cognitive decline: A diffusion kurtosis and neurite orientation dispersion and density imaging study.

Authors: Flaherty R; Department of Radiology, New York University Grossman School of Medicine, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA., Sui YV; Department of Radiology, New York University Grossman School of Medicine, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, USA., Masurkar AV; Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA.; Department of Neurology, New York University Grossman School of Medicine, Center for Cognitive Neurology, New York, NY, USA.; Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Youss ZB; Department of Radiology, New York University Grossman School of Medicine, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA., Wisniewski T; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA.; Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA.; Department of Neurology, New York University Grossman School of Medicine, Center for Cognitive Neurology, New York, NY, USA.; Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Rusinek H; Department of Radiology, New York University Grossman School of Medicine, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, USA.; Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA., Lazar M; Department of Radiology, New York University Grossman School of Medicine, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA.

Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 Jul; Vol. 112 (2), pp. 728-740. Date of Electronic Publication: 2026 May 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE

MeSH Terms: Amygdala*/diagnostic imaging , Amygdala*/pathology , Cognitive Dysfunction*/diagnostic imaging , Cognitive Dysfunction*/pathology , Cognitive Dysfunction*/psychology , Neurites*/pathology, Diffusion Magnetic Resonance Imaging/methods ; Diffusion Tensor Imaging/methods ; Humans ; Male ; Female ; Aged ; Middle Aged ; Anisotropy

Longitudinal Trajectories of Global and Domain-Specific Cognition After Stroke Using the Oxford Cognitive Screen.

Authors: Milosevich E; Investigative Medicine Division, Radcliffe Department of Medicine (E.M.), University of Oxford, United Kingdom., Kusec A; Nuffield Department of Clinical Neurosciences (A.K., N.D.), University of Oxford, United Kingdom., Pendlebury ST; Nuffield Department of Clinical Neurosciences, Wolfson Centre for Prevention of Stroke and Dementia (S.T.P.), University of Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre and Departments of General Medicine and Geratology, John Radcliffe Hospital, Oxford, United Kingdom (S.T.P.)., Demeyere N; Nuffield Department of Clinical Neurosciences (A.K., N.D.), University of Oxford, United Kingdom.

Source: Stroke [Stroke] 2026 Jul; Vol. 57 (7), pp. 2150-2162. Date of Electronic Publication: 2026 May 19.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

MeSH Terms: Stroke*/complications , Stroke*/psychology , Cognition*/physiology , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/diagnosis , Cognitive Dysfunction*/psychology, Humans ; Female ; Aged ; Male ; Longitudinal Studies ; Middle Aged ; Neuropsychological Tests ; Executive Function

CypA inhibition attenuates diabetic hypoglycemia-induced cognitive impairment via the CD147/NF-κB/MMP-9 pathway.

Authors: Lin L; 900th Hospital of PLA Joint Logistic Support Force, Fuzhou 350001, China., Huang Z; School of Pharmacy, Fujian Medical University, Fuzhou 350122, China., Huang Q; Fujian Medical University Union Hospital, Fuzhou 350001, China., Huang C; Fujian Medical University Union Hospital, Fuzhou 350001, China., Wu Y; Fujian Medical University Union Hospital, Fuzhou 350001, China., Lin M; Fujian Medical University Union Hospital, Fuzhou 350001, China., Liu L; Fujian Medical University Union Hospital, Fuzhou 350001, China. Electronic address: libinliu@fjmu.edu.cn., Chen Z; School of Pharmacy, Fujian Medical University, Fuzhou 350122, China. Electronic address: chenzhou@fjmu.edu.cn.

Source: Biochemical pharmacology [Biochem Pharmacol] 2026 Jul; Vol. 249, pp. 117917. Date of Electronic Publication: 2026 Mar 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Matrix Metalloproteinase 9*/metabolism , Cyclophilin A*/antagonists & inhibitors , Cyclophilin A*/metabolism , NF-kappa B*/metabolism , Hypoglycemia*/metabolism , Hypoglycemia*/complications , Hypoglycemia*/drug therapy , Hypoglycemia*/chemically induced , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/chemically induced , Basigin*/metabolism , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/prevention & control, Signal Transduction/drug effects ; Signal Transduction/physiology ; Cyclosporine/pharmacology ; Cyclosporine/therapeutic use ; Animals ; Male ; Mice ; Humans ; Mice, Inbred C57BL

Polystyrene nanoplastics induce hippocampal damage and cognitive deficits through oxidative stress-triggered microglial extracellular traps and neuronal ferroptosis.

Authors: Hu J; Hubei Clinical Research Center for Alzheimer's Disease, Brain Science and Advanced Technology Institute, School of Medicine, Wuhan University of Science and Technology, Wuhan, China., Chen Y; Hubei Clinical Research Center for Alzheimer's Disease, Brain Science and Advanced Technology Institute, School of Medicine, Wuhan University of Science and Technology, Wuhan, China., Xu L; Hubei Clinical Research Center for Alzheimer's Disease, Brain Science and Advanced Technology Institute, School of Medicine, Wuhan University of Science and Technology, Wuhan, China., Dai A; Hubei Clinical Research Center for Alzheimer's Disease, Brain Science and Advanced Technology Institute, School of Medicine, Wuhan University of Science and Technology, Wuhan, China., Li J; Hubei Clinical Research Center for Alzheimer's Disease, Brain Science and Advanced Technology Institute, School of Medicine, Wuhan University of Science and Technology, Wuhan, China. Electronic address: lijinquan@wust.edu.cn., Liu X; School of Food Engineering, Moutai Institute, Renhuai, China. Electronic address: xudongliu168@163.com.

Source: Chemico-biological interactions [Chem Biol Interact] 2026 Jul 01; Vol. 434, pp. 112120. Date of Electronic Publication: 2026 May 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

MeSH Terms: Oxidative Stress*/drug effects , Ferroptosis*/drug effects , Hippocampus*/drug effects , Hippocampus*/pathology , Hippocampus*/metabolism , Microglia*/drug effects , Microglia*/metabolism , Microglia*/cytology , Polystyrenes*/chemistry , Polystyrenes*/toxicity , Extracellular Traps*/drug effects , Extracellular Traps*/metabolism , Cognitive Dysfunction*/chemically induced , Cognitive Dysfunction*/pathology , Cognitive Dysfunction*/metabolism , Nanoparticles*/toxicity , Nanoparticles*/chemistry , Microplastics*/toxicity , Microplastics*/chemistry, Neurons/drug effects ; Neurons/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Lipid Peroxidation/drug effects ; Animals ; Mice ; Male ; Mice, Inbred C57BL