Click Chemistry: an overview and recent updates in the medicinal attributes of click-derived heterocycles.

Συγγραφείς: Bishnoi P; Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India, 136119., Saroha B; Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India, 136119.; Department of Chemistry, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonipat, India., Kumar S; Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India, 136119. suresh_dua47@rediffmail.com., Kumar G; Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India, 136119.; Biomedical Engineering Department, Oregon Health & Science University, Portland, OR, 97201, USA., Bhardwaj A; Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India, 136119., Kumari M; Department of Chemistry, Govt. College for Women, Badhra, Charkhi Dadri, Haryana, 127308, India., Kumar N; Department of Chemistry, Maharishi Dayanand University, Rohtak, Haryana, 124001, India.

Πηγή: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5219-5281. Date of Electronic Publication: 2025 Feb 07.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Click Chemistry*/methods , Heterocyclic Compounds*/chemistry , Heterocyclic Compounds*/chemical synthesis , Heterocyclic Compounds*/pharmacology, Cycloaddition Reaction ; Azides/chemistry ; Humans ; Catalysis ; Alkynes/chemistry ; Chemistry, Pharmaceutical/methods ; Drug Discovery/methods

Green synthesis, anti-inflammatory evaluation and molecular docking of novel pyridines via one pot multi-component reaction using ultrasonic irradiation.

Συγγραφείς: Elkanzi NAA; Department of Chemistry, College of Science, Jouf University, 72341, Sakaka, Aljouf, Saudi Arabia. nahasan@ju.edu.sa., Ali AM; Department of Chemistry, Faculty of Science, Sohag University, Sohag, 82524, Egypt., Abdelaziz MA; Department of Chemistry, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia., Alsirhani AM; Department of Chemistry, College of Science, Jouf University, 72341, Sakaka, Aljouf, Saudi Arabia.

Πηγή: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5487-5497. Date of Electronic Publication: 2024 Dec 07.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Molecular Docking Simulation* , Anti-Inflammatory Agents*/chemical synthesis , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Pyridines*/chemical synthesis , Pyridines*/chemistry , Pyridines*/pharmacology , Green Chemistry Technology*/methods , Ultrasonic Waves*, Humans ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2/chemistry ; Chemistry Techniques, Synthetic ; Ibuprofen/pharmacology

Green synthesis of PVA-LS-MXene composite conductive hydrogel for high-performance skin wound dressings.

Συγγραφείς: Lei S; School/Hospital of Stomatology, Lanzhou University, Lanzhou, 730000, China; Lanzhou University Second Hospital, Lanzhou, 730030, China; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China., Qin X; Department of Stomatology, Longgang Central Hospital, Shenzhen, 518116, Guangdong, China., Shen S; School/Hospital of Stomatology, Lanzhou University, Lanzhou, 730000, China., Ma X; School/Hospital of Stomatology, Lanzhou University, Lanzhou, 730000, China; Lanzhou University Second Hospital, Lanzhou, 730030, China; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China., Yang C; School/Hospital of Stomatology, Lanzhou University, Lanzhou, 730000, China; Lanzhou University Second Hospital, Lanzhou, 730030, China., Mai X; Lanzhou University Second Hospital, Lanzhou, 730030, China., Cao X; State Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China., Liu Z; State Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China., Xie W; School/Hospital of Stomatology, Lanzhou University, Lanzhou, 730000, China; Lanzhou University Second Hospital, Lanzhou, 730030, China. Electronic address: jiewb@lzu.edu.cn., Yang S; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China., Wang J; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: jqwang@licp.cas.cn.

Πηγή: Journal of the mechanical behavior of biomedical materials [J Mech Behav Biomed Mater] 2025 Oct; Vol. 170, pp. 107107. Date of Electronic Publication: 2025 Jun 19.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101322406 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0180 (Electronic) Linking ISSN: 18780180 NLM ISO Abbreviation: J Mech Behav Biomed Mater Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Polyvinyl Alcohol*/chemistry , Bandages* , Hydrogels*/chemistry , Hydrogels*/pharmacology , Hydrogels*/chemical synthesis , Electric Conductivity* , Lignin*/chemistry , Green Chemistry Technology* , Skin*/drug effects, Animals ; Wound Healing/drug effects ; Mice ; Biocompatible Materials/chemistry ; Biocompatible Materials/pharmacology ; Chemistry Techniques, Synthetic ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Tensile Strength ; Staphylococcus aureus/drug effects ; Nitrites ; Transition Elements

Growing impact of 'Click chemistry' inspired glycohybrid 1,2,3-Triazoles in organic synthesis.

Συγγραφείς: Singh SK; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India; Department of Chemistry, Govt. P.G. College, Amarpatan, Maihar, Madhya Pradesh, 485775, India., Sharma A; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India; Department of Chemistry, A.P.S.M. College, Barauni, Begusarai, Bihar, 851112, India., Mishra N; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India; Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University, Dehradun, Uttarakhand, 248007, India., Tiwari VK; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India. Electronic address: Vinod.Tiwari@bhu.ac.in.

Πηγή: Carbohydrate research [Carbohydr Res] 2025 Sep; Vol. 555, pp. 109571. Date of Electronic Publication: 2025 Jun 09.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0043535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-426X (Electronic) Linking ISSN: 00086215 NLM ISO Abbreviation: Carbohydr Res Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Triazoles*/chemistry , Click Chemistry* , Glycoconjugates*/chemistry , Glycoconjugates*/chemical synthesis, Catalysis ; Chemistry Techniques, Synthetic ; Stereoisomerism ; Molecular Structure

A comprehensive review of green approaches to drug solubility enhancement.

Συγγραφείς: Mahesha BS; Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore, Karnataka, India., Sheeba FR; Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore, Karnataka, India., Deepak HK; Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore, Karnataka, India.

Πηγή: Drug development and industrial pharmacy [Drug Dev Ind Pharm] 2025 Jul; Vol. 51 (7), pp. 659-669. Date of Electronic Publication: 2025 Apr 27.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Informa Healthcare Country of Publication: England NLM ID: 7802620 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5762 (Electronic) Linking ISSN: 03639045 NLM ISO Abbreviation: Drug Dev Ind Pharm Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Green Chemistry Technology*/methods, Solubility ; Pharmaceutical Preparations/chemistry ; Excipients/chemistry ; Polymers/chemistry ; Solvents/chemistry ; Chemistry, Pharmaceutical/methods ; Drug Compounding/methods ; Humans ; Biological Availability

Recent Applications of Disulfide Bond-Containing Compounds in Medicinal and Agrochemical Chemistry.

Συγγραφείς: Liu S; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China., Zhang P; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China., Zhao Z; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China., Li M; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China., Jin Z; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China., Lu A; School of Chemical Engineering and Technology, Hebei University of Technology, Hebei Collaborative Innovation Center of Modern Marine Chemical Technology, Tianjin 300130, China., Wang Q; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China., Wang Z; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China.

Πηγή: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Dec 03; Vol. 73 (48), pp. 30601-30627. Date of Electronic Publication: 2025 Nov 20.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Agrochemicals*/chemistry , Agrochemicals*/pharmacology , Disulfides*/chemistry , Disulfides*/pharmacology, Animals ; Fusarium/drug effects ; Chemistry, Pharmaceutical/methods ; Humans

Enhancing Antigen Recognition of Living Cells by Site-Specific VHH Antibody Conjugation.

Συγγραφείς: Zhu C; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan., Ichikawa Y; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan., Yamashita F; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan., Higuchi Y; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan.

Πηγή: Chembiochem : a European journal of chemical biology [Chembiochem] 2025 Nov 17; Vol. 26 (22), pp. e202500504. Date of Electronic Publication: 2025 Oct 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Single-Domain Antibodies*/chemistry , Single-Domain Antibodies*/immunology , Antigens*/immunology , Antigens*/chemistry , Antibodies, Immobilized*/chemistry , Antibodies, Immobilized*/immunology, Humans ; HeLa Cells ; Azides/chemistry ; Click Chemistry ; Phenylalanine/chemistry ; Phenylalanine/analogs & derivatives ; Red Fluorescent Protein ; Luminescent Proteins/immunology ; Luminescent Proteins/chemistry

A multivariate optimization of a green ultrasound-assisted extraction method using a natural deep eutectic solvent for the determination of Fe, Mn, and Zn in instant coffee samples by F AAS.

Συγγραφείς: Costa GC; Universidade Federal da Bahia, Instituto de Química, Campus de Ondina, 40170-115, Salvador, BA, Brazil., Soares LM; Universidade Federal da Bahia, Instituto de Química, Campus de Ondina, 40170-115, Salvador, BA, Brazil., Junior JBP; Departamento de Ciências Exatas, Universidade Estadual de Feira de Santana, 44036-900, Feira de Santana, BA, Brazil., Araujo RGO; Universidade Federal da Bahia, Instituto de Química, Campus de Ondina, 40170-115, Salvador, BA, Brazil., Cunha FAS; Universidade Federal da Bahia, Instituto de Química, Campus de Ondina, 40170-115, Salvador, BA, Brazil. Electronic address: francisco.cunha@ufba.br.

Πηγή: Food chemistry [Food Chem] 2025 Nov 01; Vol. 491, pp. 145271. Date of Electronic Publication: 2025 Jun 25.

Τύπος έκδοσης: Journal Article; Evaluation Study

Στοιχεία περιοδικού: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Manganese*/isolation & purification , Manganese*/analysis , Coffee*/chemistry , Zinc*/isolation & purification , Zinc*/analysis , Spectrophotometry, Atomic*/methods , Iron*/isolation & purification , Iron*/analysis , Coffea*/chemistry , Chemical Fractionation*/methods , Chemical Fractionation*/instrumentation, Deep Eutectic Solvents/chemistry ; Food Contamination/analysis ; Green Chemistry Technology/methods ; Sonication/methods

Glycosylation-enabled chemoselective growth factor engineering for biomaterial functionalization.

Συγγραφείς: Xing Y; Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, United States., Li Q; Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, United States., Otto EL; Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, United States., Campbell PG; Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, United States., Ren X; Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, United States. Electronic address: xiren@cmu.edu.

Πηγή: Acta biomaterialia [Acta Biomater] 2025 Nov; Vol. 207, pp. 221-232. Date of Electronic Publication: 2025 Oct 01.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Biocompatible Materials*/chemistry , Biocompatible Materials*/pharmacology , Protein Engineering*/methods , Vascular Endothelial Growth Factor A*/chemistry , Vascular Endothelial Growth Factor A*/pharmacology, Glycosylation ; Humans ; Click Chemistry ; Animals ; Extracellular Matrix/chemistry ; Hydrogels/chemistry

Click conjugation of trivalent mannosyl glycocluster with human serum albumin to generate a cell targeting delivery vehicle.

Συγγραφείς: Zhou YF; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China., Xu H; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China., Chen DY; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China., Hu XL; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China. Electronic address: xlhu@ecust.edu.cn., Chen GR; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China., James TD; Department of Chemistry, University of Bath, Bath, UK; School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, PR China. Electronic address: T.D.James@bath.ac.uk., He XP; Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China; The International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, National Center for Liver Cancer, Shanghai 200438, China. Electronic address: xphe@ecust.edu.cn.

Πηγή: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2025 Nov 01; Vol. 129, pp. 118335. Date of Electronic Publication: 2025 Jul 29.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Serum Albumin, Human*/chemistry , Mannosides*/chemistry , Mannosides*/chemical synthesis , Mannose*/chemistry , Drug Delivery Systems*, Humans ; Click Chemistry ; Azides/chemistry ; Molecular Structure

Unspecified degradation impurities identification and characterization in bilastine and montelukast tablet formulations by using UPLC and LCMS/MS: Robustness by design expert and green assessment.

Συγγραφείς: Kodishala RK; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Aziznagar, Hyderabad, Telangana 500075, India., Sayyad K; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Aziznagar, Hyderabad, Telangana 500075, India., Kowtharapu LP; GITAM Deemed to be University, Department of Chemistry, School of Science, Hyderabad, Telangana 502329, India., Konduru N; GITAM Deemed to be University, Department of Chemistry, School of Science, Hyderabad, Telangana 502329, India., Mondal T; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Aziznagar, Hyderabad, Telangana 500075, India., Varkolu M; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Aziznagar, Hyderabad, Telangana 500075, India., Gundekari S; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Aziznagar, Hyderabad, Telangana 500075, India. Electronic address: sreedhar.gundekari@gmail.com.

Πηγή: Annales pharmaceutiques francaises [Ann Pharm Fr] 2025 Nov; Vol. 83 (6), pp. 1092-1113. Date of Electronic Publication: 2025 Apr 26.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier Masson Editeur Country of Publication: France NLM ID: 2985176R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-803X (Electronic) Linking ISSN: 00034509 NLM ISO Abbreviation: Ann Pharm Fr Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Quinolines*/analysis , Quinolines*/chemistry , Drug Contamination* , Acetates*/analysis , Acetates*/chemistry , Piperidines*/analysis , Piperidines*/chemistry , Benzimidazoles*/analysis , Benzimidazoles*/chemistry, Tablets ; Sulfides ; Chromatography, High Pressure Liquid ; Cyclopropanes ; Tandem Mass Spectrometry ; Green Chemistry Technology ; Chromatography, Liquid ; Reproducibility of Results ; Chemistry, Pharmaceutical ; Drug Stability

High-Performance Odorant Receptor-Derived Peptide Sensor Based on Click Chemistry for Detecting o -Xylene Released from Paints.

Συγγραφείς: Wang Z; College of Computer and Control Engineering, Northeast Forestry University, Harbin, Heilongjiang 150040, P. R. China., Wang G; College of Computer and Control Engineering, Northeast Forestry University, Harbin, Heilongjiang 150040, P. R. China., Yan S; College of Forestry, Northeast Forestry University, Harbin, Heilongjiang 150040, P. R. China., Ma W; College of Forestry, Northeast Forestry University, Harbin, Heilongjiang 150040, P. R. China.

Πηγή: ACS sensors [ACS Sens] 2025 Oct 24; Vol. 10 (10), pp. 7438-7445. Date of Electronic Publication: 2025 Sep 30.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101669031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-3694 (Electronic) Linking ISSN: 23793694 NLM ISO Abbreviation: ACS Sens Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Click Chemistry*/methods , Receptors, Odorant*/chemistry , Paint*/analysis , Xylenes*/analysis , Peptides*/chemistry, Nanotubes, Carbon/chemistry ; Limit of Detection ; Alkynes/chemistry

Mechanistic analysis of diverse click reactions along with their applications.

Συγγραφείς: Bhatia S; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, 151401, India., Biharee A; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, 151401, India., Mondal S; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, 151401, India., Kulkarni S; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, 151401, India., Kumar R; Laboratory of Organic Chemistry, Department of Chemistry, Central University of Punjab, Bathinda, Punjab, 151401, India., Thareja S; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, 151401, India. Electronic address: sureshthareja@gmail.com.

Πηγή: European journal of medicinal chemistry [Eur J Med Chem] 2025 Oct 15; Vol. 296, pp. 117800. Date of Electronic Publication: 2025 May 28.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Click Chemistry*, Alkynes/chemistry ; Cycloaddition Reaction ; Azides/chemistry ; Humans ; Copper/chemistry ; Catalysis ; Molecular Structure

Modification of Amino-Functionalized Organic-Silica Hybrid Monoliths via a Catalyst-Free Amino-Yne Click Reaction for Capillary Liquid Chromatography.

Συγγραφείς: Huang Z; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., Wang H; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., He W; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., Qin S; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., Chen Y; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., Cai S; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., Luo J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China., Deng M; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China.

Πηγή: Electrophoresis [Electrophoresis] 2025 Oct; Vol. 46 (19), pp. 1479-1485. Date of Electronic Publication: 2025 Sep 08.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 8204476 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2683 (Electronic) Linking ISSN: 01730835 NLM ISO Abbreviation: Electrophoresis Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Silicon Dioxide*/chemistry , Click Chemistry*/methods , Alkynes*/chemistry, Chromatography, Liquid/methods ; Chromatography, Liquid/instrumentation ; Lignans/analysis ; Lignans/chemistry ; Biphenyl Compounds/analysis ; Biphenyl Compounds/chemistry ; Microscopy, Electron, Scanning ; Spectroscopy, Fourier Transform Infrared

Artificial Intelligence tool for prediction of ECM mimics hydrogel formulations via click chemistry.

Συγγραφείς: Cadamuro F; University of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy., Piazzoni M; University of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy., Gamba E; University of Bergamo, Department of Management, Information and Production Engineering, Bergamo, Italy., Sonzogni B; University of Bergamo, Department of Management, Information and Production Engineering, Bergamo, Italy., Previdi F; University of Bergamo, Department of Management, Information and Production Engineering, Bergamo, Italy., Nicotra F; University of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy., Ferramosca A; University of Bergamo, Department of Management, Information and Production Engineering, Bergamo, Italy. Electronic address: antonio.ferramosca@unibg.it., Russo L; University of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy; Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy. Electronic address: laura.russo@unimib.it.

Πηγή: Biomaterials advances [Biomater Adv] 2025 Oct; Vol. 175, pp. 214323. Date of Electronic Publication: 2025 Apr 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hydrogels*/chemistry , Click Chemistry* , Extracellular Matrix*/chemistry , Artificial Intelligence* , Biomimetic Materials*/chemistry, Gelatin/chemistry ; Tissue Engineering ; Humans ; Hyaluronic Acid/chemistry ; Bioprinting ; Rheology ; Machine Learning ; Biocompatible Materials/chemistry

Hyaluronic Acid/Type I Collagen Hydrogels With Tunable Physicochemical Properties Using Diels-Alder Click Chemistry.

Συγγραφείς: Fatima R; Department of Chemical and Biomolecular Engineering, Clarkson University, Potsdam, New York, USA., Almeida B; Department of Chemical and Biomolecular Engineering, Clarkson University, Potsdam, New York, USA.

Πηγή: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2025 Oct; Vol. 113 (10), pp. e37992.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101234237 Publication Model: Print Cited Medium: Internet ISSN: 1552-4965 (Electronic) Linking ISSN: 15493296 NLM ISO Abbreviation: J Biomed Mater Res A Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hydrogels*/chemistry , Hyaluronic Acid*/chemistry , Click Chemistry*/methods , Collagen Type I*/chemistry, Cycloaddition Reaction ; Animals ; Humans ; Polyethylene Glycols/chemistry ; Furans/chemistry ; Tissue Engineering

Systematic formulation optimisation to enhance buffer exchange recovery and storage stability for adeno-associated virus (AAV2) vectors.

Συγγραφείς: Carrillo Sanchez B; Department of Biochemical Engineering, University College London, London WC1E 6BT, United Kingdom., Fernández-García R; School of Pharmacy, Boots Science Building, University of Nottingham, Nottingham NG7 2RD, United Kingdom., Gerontas S; Pharmaron Biologics Ltd., Liverpool L24 8RB, United Kingdom. Electronic address: spyridon.gerontas@pharmaron-uk.com., Hales JE; Department of Biochemical Engineering, University College London, London WC1E 6BT, United Kingdom., Aylott JW; School of Pharmacy, Boots Science Building, University of Nottingham, Nottingham NG7 2RD, United Kingdom., Dalby PA; Department of Biochemical Engineering, University College London, London WC1E 6BT, United Kingdom. Electronic address: p.dalby@ucl.ac.uk.

Πηγή: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126312. Date of Electronic Publication: 2025 Oct 26.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Dependovirus*/genetics , Dependovirus*/chemistry , Genetic Vectors*/chemistry, Excipients/chemistry ; Buffers ; Drug Stability ; Chemistry, Pharmaceutical/methods ; Humans ; Drug Storage ; Chromatography, High Pressure Liquid ; Drug Compounding/methods

Investigating the effects of formulation and manufacturing routes on the tensile strength and disintegration time of tablets containing an HPMC AS-based spray dried powder.

Συγγραφείς: Marcozzi T; Janssen Pharmaceutica NV, A Johnson & Johnson Company, Turnhoutseweg 30, 2340 Beerse, Belgium; Ghent University, Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Otava M; Janssen-Cilag s.r.o., A Johnson & Johnson Company, Walterovo namesti 329/1, 15800 Prague, Czechia., Andersen SK; Janssen Pharmaceutica NV, A Johnson & Johnson Company, Turnhoutseweg 30, 2340 Beerse, Belgium., Vervaet C; Ghent University, Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Vanhoorne V; Ghent University, Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ottergemsesteenweg 460, B-9000 Ghent, Belgium. Electronic address: valerie.vanhoorne@ugent.be.

Πηγή: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126314. Date of Electronic Publication: 2025 Oct 30.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Hypromellose Derivatives*/chemistry , Excipients*/chemistry, Tensile Strength ; Tablets/chemistry ; Powders/chemistry ; Solubility ; Chemistry, Pharmaceutical/methods ; Mannitol/chemistry ; Spray Drying ; Drug Compounding/methods ; Cellulose/chemistry ; Carboxymethylcellulose Sodium/chemistry ; Povidone/chemistry

Machine Learning-Guided microfluidic optimization of clinically inspired liposomes for nanomedicine applications.

Συγγραφείς: Buttitta G; Department of Drug Chemistry and Technologies, University of Rome 'La Sapienza', P.le A. Moro 5, 00185 Rome, Italy. Electronic address: giorgio.buttitta@uniroma1.it., Lavagna L; Department of Information Engineering, Electronics and Telecommunications, University of Rome 'La Sapienza', Via Eudossiana 18, 00184 Rome, Italy., Bonacorsi S; Department of Drug Chemistry and Technologies, University of Rome 'La Sapienza', P.le A. Moro 5, 00185 Rome, Italy; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Barbarito C; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Moliterno M; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Saito G; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Oddone I; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Verdone G; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Raimondi S; BSP Pharmaceuticals, Via Appia, km. 65, 561, 04100 Latina, LT, Italy., Panella M; Department of Information Engineering, Electronics and Telecommunications, University of Rome 'La Sapienza', Via Eudossiana 18, 00184 Rome, Italy.

Πηγή: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126362. Date of Electronic Publication: 2025 Nov 04.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Machine Learning* , Liposomes*/chemistry , Nanomedicine*/methods , Doxorubicin*/analogs & derivatives , Doxorubicin*/chemistry , Doxorubicin*/administration & dosage , Microfluidics*/methods, Drug Delivery Systems/methods ; Particle Size ; Polyethylene Glycols/chemistry ; Drug Compounding/methods ; Chemistry, Pharmaceutical/methods

Mitigating polysorbate degradation-induced visible particle formation in an antibody formulation: From root cause identification to strategic solution.

Συγγραφείς: Hu T; Department of Gastroenterology, Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China; Biologics Technical Development, BeOne Medicines, Beijing, China., Yi M; Biologics Technical Development, BeOne Medicines, Beijing, China., Zhang Z; Biologics Technical Development, BeOne Medicines, Beijing, China., Guo X; Biologics Technical Development, BeOne Medicines, Beijing, China., Fan Y; Biologics Technical Development, BeOne Medicines, Beijing, China., Duan T; Biologics Technical Development, BeOne Medicines, Beijing, China., Li X; Biologics Technical Development, BeOne Medicines, Beijing, China., Zhang Y; Biologics Technical Development, BeOne Medicines, Beijing, China., Kang Y; Biologics Technical Development, BeOne Medicines, Beijing, China., Jiang W; Biologics Technical Development, BeOne Medicines, Beijing, China., Chen Z; Biologics Technical Development, BeOne Medicines, Beijing, China., Chen S; Department of Gastroenterology, Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China; Department of Burn and Plastic Surgery, Shenzhen Key Laboratory of Microbiology in Genomic Modification & Editing and Application, Shenzhen Institute of Translational Medicine, Shenzhen University Medical School, The First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China. Electronic address: shichen@whu.edu.cn., Song J; Biologics Technical Development, BeOne Medicines, Beijing, China. Electronic address: jing.song@beonemed.com.

Πηγή: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126311. Date of Electronic Publication: 2025 Oct 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Polysorbates*/chemistry , Antibodies, Monoclonal*/chemistry, Phospholipases A2/metabolism ; Phospholipases A2/genetics ; Animals ; CHO Cells ; Cricetulus ; Hydrolysis ; Chemistry, Pharmaceutical/methods ; Drug Compounding/methods ; Fatty Acids, Nonesterified/chemistry ; Fatty Acids, Nonesterified/metabolism