AAV Vectors in Regenerative Medicine and Cellular Reprogramming: Potential, Pitfalls, and Specificity Constraints.

Συγγραφείς: Abdelnaby M; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), Institutskiy Per., 141701 Dolgoprudny, Russia.; Research Institute of Translational Medicine, Pirogov Russian National Research Medical University, Ostrovitianov Street, 117997 Moscow, Russia., Galiakberova A; Research Institute of Translational Medicine, Pirogov Russian National Research Medical University, Ostrovitianov Street, 117997 Moscow, Russia.; Research Institute of Molecular and Cellular Medicine, RUDN University, 117198 Moscow, Russia., Dashinimaev E; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), Institutskiy Per., 141701 Dolgoprudny, Russia.; Research Institute of Translational Medicine, Pirogov Russian National Research Medical University, Ostrovitianov Street, 117997 Moscow, Russia.; Research Institute of Molecular and Cellular Medicine, RUDN University, 117198 Moscow, Russia.; Medical Institute, Banzarov Buryat State University, 670000 Ulan-Ude, Russia.

Πηγή: International journal of molecular sciences [Int J Mol Sci] 2026 Jul 30; Vol. 27 (15). Date of Electronic Publication: 2026 Jul 30.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Regenerative Medicine*/methods , Genetic Vectors*/genetics , Dependovirus*/genetics, Genetic Therapy/methods ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/cytology ; Humans ; Animals ; Gene Transfer Techniques ; Gene Therapy Agents ; Transduction, Genetic

Cellular reprogramming beyond pluripotency.

Συγγραφείς: Núñez-Quintela V; Laboratory of Cell Senescence, Cancer and Aging, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. Electronic address: victor.nunez.quintela@rai.usc.es., Li H; Cellular Plasticity in Age-related Pathologies, Department of Developmental and Stem Cell Biology, CNRS UMR 3738, Université Paris Cité, Institut Pasteur, Paris, France., Collado M; Laboratory of Cell Senescence, Cancer and Aging, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Department of Immunology and Oncology (DIO), Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. Electronic address: manuel.collado@usc.es.

Πηγή: Trends in molecular medicine [Trends Mol Med] 2026 Aug; Vol. 32 (8), pp. 810-821. Date of Electronic Publication: 2026 Mar 20.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Aging*/genetics , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/metabolism, Humans ; Animals ; Regeneration

A protoplast-based method to visualize early cell biological events in plant cellular reprogramming and regeneration.

Συγγραφείς: Reed KM; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Masri AA; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Hanrahan AJ; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Ng EL; Facility for Advanced Imaging and Microscopy, Fralin Life Sciences Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA., Li M; Donald Danforth Plant Sciences Center, St. Louis, MO 63132, USA., Bargmann BOR; School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

Πηγή: Development (Cambridge, England) [Development] 2026 Sep 15; Vol. 153 (18). Date of Electronic Publication: 2026 Sep 15.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Protoplasts*/metabolism , Protoplasts*/cytology , Protoplasts*/physiology , Arabidopsis*/cytology , Arabidopsis*/physiology , Regeneration*/physiology , Cellular Reprogramming*/physiology , Plant Cells*

Wounding activates the HSFA1 transcription factors to promote cellular reprogramming in Arabidopsis.

Συγγραφείς: Coleman D; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; Department of Biological Sciences, Faculty of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan., Iwase A; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; JST, PRESTO, 7 Goban-cho, Chiyoda-ku, Tokyo 102-0076Japan., Kawamura A; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Takebayashi A; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Chen Y; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Minne M; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Jager KE; Leibniz-Institut für Gemüse- und Zierpflanzenbau, Theodor-Echtermeyer-Weg 1, Großbeeren 14979, Germany., Peng M; Leibniz-Institut für Gemüse- und Zierpflanzenbau, Theodor-Echtermeyer-Weg 1, Großbeeren 14979, Germany., Kodama Y; Center for Bioscience Research and Education, Utsunomiya University, 350 Mine-machi, Utsunomiya, Tochigi 331-8505, Japan., Favero DS; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Takahashi T; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan., Ikeuchi M; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; Division of Biological Sciences, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5, Takayama-cho, Ikoma, Nara 630-0192, Japan., Suzuki T; Department of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan., Ohama N; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan., Yamaguchi-Shinozaki K; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan., Wigge PA; Leibniz-Institut für Gemüse- und Zierpflanzenbau, Theodor-Echtermeyer-Weg 1, Großbeeren 14979, Germany.; Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25 Haus 25, Raum B1.11-12, Potsdam 14476, Germany., De Veylder L; Department of Plant Biotechnology and Bioinformatics, Ghent University, Gent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Sugimoto K; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi Ward, Yokohama, Kanagawa 230-0045, Japan.; Department of Biological Sciences, Faculty of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Πηγή: The Plant cell [Plant Cell] 2026 Jun 02; Vol. 38 (6).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 9208688 Publication Model: Print Cited Medium: Internet ISSN: 1532-298X (Electronic) Linking ISSN: 10404651 NLM ISO Abbreviation: Plant Cell Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Arabidopsis*/genetics , Arabidopsis*/metabolism , Arabidopsis*/physiology , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Cellular Reprogramming*/genetics , Cellular Reprogramming*/physiology , Heat Shock Transcription Factors*/metabolism , Heat Shock Transcription Factors*/genetics , Transcription Factors*/metabolism , Transcription Factors*/genetics, Gene Expression Regulation, Plant/genetics

Functional suppression accompanies internal mitochondrial reorganization during cellular reprogramming.

Συγγραφείς: Diak N; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Sieroń L; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Janelt K; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Chajec L; Faculty of Natural Sciences, Institute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, Bankowa 9, 40-007, Katowice, Poland., Fus-Kujawa A; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Dziedzic-Kowalska A; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Trybus A; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland., Raszczok K; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland.; Students Scientific Society, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland., Bajdak-Rusinek K; Department of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18 Street, 40-752, Katowice, Poland. kbajdak-rusinek@sum.edu.pl.

Πηγή: Histochemistry and cell biology [Histochem Cell Biol] 2026 Apr 20; Vol. 164 (1). Date of Electronic Publication: 2026 Apr 20.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Springer Country of Publication: Germany NLM ID: 9506663 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-119X (Electronic) Linking ISSN: 09486143 NLM ISO Abbreviation: Histochem Cell Biol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Mitochondria*/metabolism , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology , Cellular Reprogramming*, Fibroblasts/metabolism ; Fibroblasts/cytology ; Reactive Oxygen Species/metabolism ; Humans ; Cells, Cultured ; Membrane Potential, Mitochondrial

Phospholipid remodeling interplays with auxin signaling to modulate cellular reprogramming in Arabidopsis regeneration.

Συγγραφείς: Chang P; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Henan Sesame Research Center, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China., Yang X; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Liu X; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Guo S; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Zhou J; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., He M; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Li Z; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Xu E; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China., Xin W; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China., Hu Y; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.; National Center for Plant Gene Research, Beijing 100093, China., Xu C; Key Laboratory of Plant Molecular Physiology and State Key Laboratory of Forage Breeding-by-Design and Utilization, Institute of Botany, Chinese Academy of Sciences, China National Botanical Garden, Beijing 100093, China.

Πηγή: The Plant cell [Plant Cell] 2026 Jun 02; Vol. 38 (6).

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Oxford University Press Country of Publication: England NLM ID: 9208688 Publication Model: Print Cited Medium: Internet ISSN: 1532-298X (Electronic) Linking ISSN: 10404651 NLM ISO Abbreviation: Plant Cell Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Indoleacetic Acids*/metabolism , Indoleacetic Acids*/pharmacology , Arabidopsis*/physiology , Arabidopsis*/metabolism , Arabidopsis*/genetics , Regeneration*/physiology , Phospholipids*/metabolism , Cellular Reprogramming*, Arabidopsis Proteins/metabolism ; Arabidopsis Proteins/genetics ; Phosphatidic Acids/metabolism ; Plant Growth Regulators/metabolism ; Signal Transduction ; Gene Expression Regulation, Plant ; Plants, Genetically Modified

Protocol for identifying cellular reprogramming minimal networks using combinatorial transcription factor screening.

Συγγραφείς: Altman AR; Molecular Medicine and Gene Therapy, Science for Life Laboratory, Lund Stem Cell Center, Lund University, BMC A12, 221 84 Lund, Sweden; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Pértiga-Cabral D; Molecular Medicine and Gene Therapy, Science for Life Laboratory, Lund Stem Cell Center, Lund University, BMC A12, 221 84 Lund, Sweden; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden; CNC - Centre for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês Do Pombal, 3004-517 Coimbra, Portugal; CiBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal; Doctoral Programme in Experimental Biology and Biomedicine, University of Coimbra, Coimbra, Portugal., Pereira CF; Molecular Medicine and Gene Therapy, Science for Life Laboratory, Lund Stem Cell Center, Lund University, BMC A12, 221 84 Lund, Sweden; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden; CNC - Centre for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês Do Pombal, 3004-517 Coimbra, Portugal; CiBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal; Asgard Therapeutics AB, Medicon Village, 223 81 Lund, Sweden., Kurochkin I; Molecular Medicine and Gene Therapy, Science for Life Laboratory, Lund Stem Cell Center, Lund University, BMC A12, 221 84 Lund, Sweden; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden. Electronic address: ilia.kurochkin@med.lu.se.

Πηγή: STAR protocols [STAR Protoc] 2026 Jun 19; Vol. 7 (2), pp. 104527. Date of Electronic Publication: 2026 Apr 28.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Transcription Factors*/metabolism , Transcription Factors*/genetics , Cellular Reprogramming*/genetics, Fibroblasts/cytology ; Fibroblasts/metabolism ; Lentivirus/genetics ; Humans

A cross-talk between p16High senescence and cellular reprogramming.

Συγγραφείς: Emelyanov A; Institute for Research on Cancer and Aging of Nice (IRCAN), Université Côte d'Azur, INSERM, CNRS, Nice, France., Bulavin DV; Institute for Research on Cancer and Aging of Nice (IRCAN), Université Côte d'Azur, INSERM, CNRS, Nice, France.

Πηγή: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2026 Jun 10; Vol. 140 (6), pp. 1137-1147.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Senescence*/genetics , Cellular Senescence*/physiology , Cyclin-Dependent Kinase Inhibitor p16*/metabolism , Cyclin-Dependent Kinase Inhibitor p16*/genetics , Cellular Reprogramming*, Fibroblasts/metabolism ; Humans ; Kruppel-Like Factor 4 ; Animals ; Epigenesis, Genetic ; Signal Transduction

Distinct media requirements for dopaminergic neuron reprogramming from human glia and fibroblasts.

Συγγραφείς: Laurin K; Developmental and Regenerative Neurobiology, Lund Stem Cell Center, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden., Kajtez J; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Wickham J; Laboratory of Stem Cells and Restorative Neurology, Lund Stem Cell Center, Faculty of Medicine, Lund University, Lund, Sweden., Parmar M; Developmental and Regenerative Neurobiology, Lund Stem Cell Center, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden., Habekost M; Developmental and Regenerative Neurobiology, Lund Stem Cell Center, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden. mette.habekost@med.lu.se.; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark. mette.habekost@med.lu.se.; Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Kgs. Lyngby, 2800, Denmark. mette.habekost@med.lu.se.

Πηγή: Scientific reports [Sci Rep] 2026 Aug 17; Vol. 16 (1). Date of Electronic Publication: 2026 Aug 17.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Dopaminergic Neurons*/cytology , Dopaminergic Neurons*/metabolism , Dopaminergic Neurons*/drug effects , Fibroblasts*/cytology , Fibroblasts*/metabolism , Fibroblasts*/drug effects , Cellular Reprogramming*/drug effects , Neuroglia*/cytology , Neuroglia*/metabolism , Neuroglia*/drug effects , Culture Media*/pharmacology , Culture Media*/chemistry, Tyrosine 3-Monooxygenase/metabolism ; Dopamine/metabolism ; Humans ; Cells, Cultured ; Cellular Reprogramming Techniques

Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis.

Συγγραφείς: Zhang C; Human Phenome Institute, Fudan University, Shanghai 201203, China., Bai Y; Human Phenome Institute, Fudan University, Shanghai 201203, China., Yin Q; Human Phenome Institute, Fudan University, Shanghai 201203, China., Li J; Human Phenome Institute, Fudan University, Shanghai 201203, China., Huang K; Human Phenome Institute, Fudan University, Shanghai 201203, China., Qiu M; Human Phenome Institute, Fudan University, Shanghai 201203, China; Center for mRNA Translational Research, Fudan University, Shanghai 200438, China; Zhangjiang mRNA Innovation and Translation Center, Shanghai 201203, China. Electronic address: mqiu@fudan.edu.cn.

Πηγή: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Feb 10; Vol. 390, pp. 114569. Date of Electronic Publication: 2025 Dec 22.

Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Nanoparticles*/administration & dosage , Nanoparticles*/chemistry , RNA, Messenger*/administration & dosage , Hepatocytes*/metabolism , Liver Cirrhosis*/therapy , Liver Cirrhosis*/genetics , Liver Cirrhosis*/pathology , Octamer Transcription Factor-3*/genetics , Lipids*/chemistry , Lipids*/administration & dosage , SOXB1 Transcription Factors*/genetics , Kruppel-Like Transcription Factors*/genetics , Cellular Reprogramming*, Animals ; Kruppel-Like Factor 4 ; Mice, Inbred C57BL ; Male ; Mice ; Humans ; Liposomes

Navigating the landscape of direct cellular reprogramming with DiReG.

Συγγραφείς: Lauber M; Data Science in Systems Biology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany., List M; Data Science in Systems Biology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany. markus.list@tum.de.; Munich Data Science Institute (MDSI), Technical University of Munich, Garching, Germany. markus.list@tum.de.

Πηγή: NPJ systems biology and applications [NPJ Syst Biol Appl] 2026 Feb 06; Vol. 12 (1). Date of Electronic Publication: 2026 Feb 06.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-7189 (Electronic) Linking ISSN: 20567189 NLM ISO Abbreviation: NPJ Syst Biol Appl Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Cellular Reprogramming*/physiology , Computational Biology*/methods, Transcription Factors/metabolism ; Transcription Factors/genetics ; Regenerative Medicine/methods ; Humans ; Animals ; Software

Redefining cellular reprogramming with advanced genomic technologies.

Συγγραφείς: Morris SA; Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. samorris2@bwh.harvard.edu.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. samorris2@bwh.harvard.edu.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA. samorris2@bwh.harvard.edu.

Πηγή: Nature reviews. Genetics [Nat Rev Genet] 2026 Mar; Vol. 27 (3), pp. 193-211. Date of Electronic Publication: 2025 Oct 17.

Τύπος έκδοσης: Journal Article; Review

Στοιχεία περιοδικού: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962779 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-0064 (Electronic) Linking ISSN: 14710056 NLM ISO Abbreviation: Nat Rev Genet Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Genomics*/methods , Cellular Reprogramming Techniques*/methods, Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Cell Differentiation/genetics ; Regenerative Medicine/methods ; Humans ; Animals ; Single-Cell Analysis

Local delivery of OSK factors enables partial cellular reprogramming to mitigate osteoarthritis and cartilage fibrosis.

Συγγραφείς: Liu YW; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Zou JT; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Gong JS; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Jin L; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Cao J; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China.; Department of Neurology, Xiangya Hospital, Central South University, Changsha, China., He ZH; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Qian YX; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Wang X; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Wan MD; National Clinical Research Center for Geriatric Disease, Xiangya Hospital, Changsha, China., Hu XY; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China.; Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China., Hong CG; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China., Du W; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China.; National Clinical Research Center for Geriatric Disease, Xiangya Hospital, Changsha, China., Chen CY; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Angmedicine, Changsha, China.; National Clinical Research Center for Geriatric Disease, Xiangya Hospital, Changsha, China., Liu HJ; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China. liuhongji@hnu.edu.cn.; Hunan Key Laboratory of Angmedicine, Changsha, China. liuhongji@hnu.edu.cn., Xie H; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China. huixie@csu.edu.cn.; Hunan Key Laboratory of Angmedicine, Changsha, China. huixie@csu.edu.cn.; National Clinical Research Center for Geriatric Disease, Xiangya Hospital, Changsha, China. huixie@csu.edu.cn., Wang ZX; Department of Orthopedics, Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, China. wangzx@csu.edu.cn.; Hunan Key Laboratory of Angmedicine, Changsha, China. wangzx@csu.edu.cn.; National Clinical Research Center for Geriatric Disease, Xiangya Hospital, Changsha, China. wangzx@csu.edu.cn.

Πηγή: Experimental & molecular medicine [Exp Mol Med] 2026 Mar; Vol. 58 (3), pp. 782-797. Date of Electronic Publication: 2026 Mar 05.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Osteoarthritis*/therapy , Osteoarthritis*/pathology , Osteoarthritis*/metabolism , Osteoarthritis*/genetics , Osteoarthritis*/etiology , Cellular Reprogramming*/genetics , Kruppel-Like Transcription Factors*/genetics , Kruppel-Like Transcription Factors*/metabolism , SOXB1 Transcription Factors*/genetics , SOXB1 Transcription Factors*/metabolism , Cartilage*/pathology , Cartilage*/metabolism, Chondrocytes/metabolism ; Dependovirus/genetics ; Genetic Vectors/genetics ; Genetic Vectors/administration & dosage ; Animals ; Mice ; Kruppel-Like Factor 4 ; Fibrosis ; Humans ; Male ; Disease Models, Animal ; Cell Differentiation

Proteomic Signatures of Cellular Reprogramming in Bladder Cancer: Insights into the Acquisition of Cancer Stem-like States and Phenotypic Plasticity.

Συγγραφείς: Barlak BSR; Protein Research and Proteomics Laboratory, Department of Medical Biology, Faculty of Medicine, Kocaeli University, Izmit, Türkiye., Iskender B; Protein Research and Proteomics Laboratory, Department of Medical Biology, Faculty of Medicine, Kocaeli University, Izmit, Türkiye banu.iskender@kocaeli.edu.tr.

Πηγή: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2026 Mar-Apr; Vol. 23 (2), pp. 300-321.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium: Internet ISSN: 1790-6245 (Electronic) Linking ISSN: 11096535 NLM ISO Abbreviation: Cancer Genomics Proteomics Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Urinary Bladder Neoplasms*/pathology , Urinary Bladder Neoplasms*/metabolism , Urinary Bladder Neoplasms*/genetics , Neoplastic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology , Proteomics*/methods , Cellular Reprogramming*, Humans ; Cell Line, Tumor ; Phenotype ; Epithelial-Mesenchymal Transition ; Cell Plasticity

Interleukin-4-mediated Pro-Regenerative Cellular Reprogramming in 3-dimensional Liver Culture.

Συγγραφείς: Camat D; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, Toronto, Ontario, Canada. Electronic address: damra.camat@mail.utoronto.ca., Nakib D; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, Toronto, Ontario, Canada. Electronic address: diana.nakib@mail.utoronto.ca., Chung SW; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Sekhon M; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Liu Y; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Lumanto P; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., Hyduk SJ; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., Perciani CT; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Bartczak AM; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Cheng ML; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Pezzutti OI; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Kaltagian M; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., Altaf F; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., Jafari SM; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., Manuel J; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., Thoeni C; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Ogawa S; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; McEwen Stem Cell Institute, University Health Network, Toronto, Ontario, Canada., Ma XZ; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada., McGilvray ID; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada. Electronic address: ian.mcgilvray@uhn.ca., MacParland SA; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address: sonya.macparland@uhn.ca.

Πηγή: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2026; Vol. 20 (2), pp. 101626. Date of Electronic Publication: 2025 Sep 02.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Interleukin-4*/pharmacology , Interleukin-4*/metabolism , Liver Regeneration*/drug effects , Cellular Reprogramming*/drug effects , Liver*/cytology , Liver*/drug effects , Liver*/pathology , Liver*/metabolism, Hepatocytes/metabolism ; Hepatocytes/drug effects ; Cell Proliferation/drug effects ; Thioacetamide/toxicity ; Adenosine Triphosphate/metabolism ; Animals ; Mice ; Mice, Inbred C57BL ; Male

In Vitro Generation of Brown and Beige Adipocytes via Cellular Reprogramming.

Συγγραφείς: Toshihiro K; Department of Cellular Regenerative Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Harada Y; Department of Pathology and Cell Regulation, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Dai P; Department of Cellular Regenerative Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Πηγή: Cellular reprogramming [Cell Reprogram] 2025 Dec; Vol. 27 (6), pp. 216-227. Date of Electronic Publication: 2025 Nov 18.

Τύπος έκδοσης: Journal Article; Review; Research Support, Non-U.S. Gov't

Στοιχεία περιοδικού: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101528176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-4998 (Electronic) Linking ISSN: 21524971 NLM ISO Abbreviation: Cell Reprogram Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Adipocytes, Beige*/cytology , Adipocytes, Beige*/metabolism , Adipocytes, Brown*/cytology , Adipocytes, Brown*/metabolism , Cellular Reprogramming Techniques*/methods , Cellular Reprogramming*, Humans ; Animals ; Thermogenesis

[Systemic Reprogramming of Cellular Senescence: Coordinated Regulation of Metabolism, Epigenetics, and Proteostasis].

Μεταγλωττισμένος Τίτλος: 细胞衰老的系统性重编程：代谢、表观遗传与蛋白稳态的协同调控.

Συγγραφείς: Zheng Y; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China., Liu Q; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China., Wang R; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China., Sun C; •（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China.

Πηγή: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2026 Jul 20; Vol. 57 (4), pp. 915-924.

Τύπος έκδοσης: Journal Article; Review; English Abstract

Στοιχεία περιοδικού: Publisher: Sichuan da xue xue bao (yi xue ban) bian ji bu Country of Publication: China NLM ID: 101162609 Publication Model: Print Cited Medium: Print ISSN: 1672-173X (Print) Linking ISSN: 1672173X NLM ISO Abbreviation: Sichuan Da Xue Xue Bao Yi Xue Ban Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Senescence*/genetics , Cellular Senescence*/physiology , Proteostasis*/genetics , Cellular Reprogramming*/genetics , Epigenesis, Genetic*, NAD/metabolism ; Humans ; Kruppel-Like Factor 4 ; Metabolic Reprogramming ; Animals

Cellular Reprogramming and Microfluidics Enable Large-Scale Blastoid Production from Aged Donors.

Συγγραφείς: Moura MT; Departamento de Biologia Celular e Molecular, Centro de Biotecnologia, Universidade Federal da Paraíba (UFPB), João Pessoa, Brasil.

Πηγή: Cellular reprogramming [Cell Reprogram] 2025 Dec; Vol. 27 (6), pp. 213-215. Date of Electronic Publication: 2025 Oct 22.

Τύπος έκδοσης: News

Στοιχεία περιοδικού: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101528176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-4998 (Electronic) Linking ISSN: 21524971 NLM ISO Abbreviation: Cell Reprogram Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Microfluidics*/methods , Blastocyst*/cytology , Cellular Reprogramming Techniques*/methods , Cellular Reprogramming* , Aging*, Animals ; Macaca mulatta ; Humans

CRISPRa-identified transcription factors reprogram glioblastoma into dendritic cell-like cells to elicit systemic antitumor immunity.

Συγγραφείς: Liu X; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China; Department of Neurosurgery, Xijing Hospital, Xi'an 710000, China., Zhu M; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Zou C; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Cao Z; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Wang Y; Air Force Medical Center of PLA, Air Force Medical University, Beijing 100000, China., Yang G; Department of Neurosurgery, Xijing Hospital, Xi'an 710000, China., Liu X; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Wu Y; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Yu D; Department of Neurosurgery, General Hospital of Central Theater Command, Wuhan, China., Zheng D; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Zhang K; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Li J; Department of Neurosurgery, Xijing Hospital, Xi'an 710000, China., Zhang W; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Wang S; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Qin H; Department of Neurosurgery, Xijing Hospital, Xi'an 710000, China., Hao Q; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Zhang Y; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Yin A; Department of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China., He Y; Department of Neurosurgery, Xijing Hospital, Xi'an 710000, China., He L; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China., Luo X; School of Basic Medicine, Fourth Military Medical University, Xi'an, China. Electronic address: 631912271@qq.com., Lin W; Department of Neurosurgery, Xijing Hospital, Xi'an 710000, China; Department of Aviation Medicine, Xijing Hospital, Xi'an, China. Electronic address: linwei@fmmu.edu.cn., Li M; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China. Electronic address: limeng@fmmu.edu.cn., Gu J; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an 710000, China. Electronic address: gujintao@fmmu.edu.cn.

Πηγή: Cell reports. Medicine [Cell Rep Med] 2026 Sep 15; Vol. 7 (9), pp. 103018. Date of Electronic Publication: 2026 Sep 01.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Glioblastoma*/immunology , Glioblastoma*/genetics , Glioblastoma*/pathology , Glioblastoma*/therapy , Dendritic Cells*/immunology , Dendritic Cells*/metabolism , Transcription Factors*/metabolism , Transcription Factors*/genetics , Cellular Reprogramming*/genetics , Brain Neoplasms*/immunology , Brain Neoplasms*/pathology , Brain Neoplasms*/genetics, Tumor Microenvironment/immunology ; Immunotherapy/methods ; Animals ; Humans ; Mice ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic

Hepatic reprogramming occurs in a time-independent manner via an initial asymmetric division and continued mitotic activity.

Συγγραφείς: Goto N; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Miura S; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan; Division of Stem Cell Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Kawamata M; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Horisawa K; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Suzuki R; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Miyata T; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Taniguchi N; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan., Suzuki A; Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan. Electronic address: suzukicks@bioreg.kyushu-u.ac.jp.

Πηγή: Stem cell reports [Stem Cell Reports] 2026 Sep 08; Vol. 21 (9), pp. 103056. Date of Electronic Publication: 2026 Aug 27.

Τύπος έκδοσης: Journal Article

Στοιχεία περιοδικού: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

Ιατρικοί όροι (MeSH): Cellular Reprogramming*/genetics , Hepatocytes*/cytology , Hepatocytes*/metabolism , Mitosis* , Asymmetric Cell Division*, Fibroblasts/cytology ; Fibroblasts/metabolism ; Animals ; Time-Lapse Imaging ; Mice ; Time Factors