Major depression and atherosclerotic disease:Linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques

Συγγραφείς: Pruin,Emma, Bartels,Meike, Benavente, Ernest Diez, van den Dungen, Noortje A M, Hoekstra, Joost K R, de Kleijn, Dominique D P, Landsmeer,Lennart P L, Mokry, Michal, Pasterkamp, Gerard, Penninx,Brenda W J H, Peyrot,Wouter J, den Ruijter, Hester M, van der Laan, Sander W, Milaneschi,Yuri, Experimentele Afd. Cardiologie 1, Circulatory Health, CDL Research analisten, Cancer, Nefro Vasculaire Geneeskunde, Zorgeenheid Vaatchirurgie Medisch, CDL Onderzoek Pasterkamp, Child Health, Centraal Diagnostisch Laboratorium, Programmabureau Zorg van Morgen, Onderzoek Vrouw Hart & Vaatziekten

Θεματικοί όροι: Pharmacology, Psychiatry and Mental health, Neurology, Genetics, Mendelian randomization, Clinical Neurology, Journal Article, Major depression, Colocalization, Pharmacology (medical), Atherosclerosis, Cardiovascular disease, Biological Psychiatry

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/469311

Genetically determined ancestry associates with morphological and molecular carotid plaque features

Συγγραφείς: Fahim,Nima, Sakkers, Tim R., van der Zalm, Floor B.H., Hoekstra, Joost, de Kleijn, Dominique P.V., Mokry, Michal, Verdezoto Mosquera, Jose, Pasterkamp, Gerard, den Ruijter, Hester M., Miller,Clint L., van Setten, Jessica, van der Laan, Sander W., Experimental Cardiology Laboratory, Experimentele Afd. Cardiologie 1, Circulatory Health, CDL Poli WKZ, CDL Onderzoek Pasterkamp, Zorgeenheid Vaatchirurgie Medisch, Nefro Vasculaire Geneeskunde, Child Health, Centraal Diagnostisch Laboratorium, Programmabureau Zorg van Morgen, Onderzoek Vrouw Hart & Vaatziekten, Cardiologie, Onderzoek Precision medicine

Θεματικοί όροι: Journal Article, Cardiology and Cardiovascular Medicine

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/469568

Atherosclerotic Fibrous Plaques in Women Present ECM Remodeling Linked to TGF-β

Συγγραφείς: Sakkers, Tim R, Mili, Eloi, Winter,Hanna, Kapteijn,Daniek, Perry,R Noah, Barbera,Nicolas, Watts,Kelsey, Dias,Inês R, Meteva,Denitsa, Wesseling, Marian, Mol, Barend M, de Borst, Gert J, de Kleijn, Dominique P V, van der Laan, Sander W, Civelek,Mete, White,Stephen J, Maegdefessel,Lars, Mayr,Manuel, Pasterkamp, Gerard, Mokry, Michal, Benavente, Ernest Diez, den Ruijter, Hester M, Experimentele Afd. Cardiologie 1, Circulatory Health, CDL Onderzoek Pasterkamp, Zorgeenheid Vaatchirurgie Medisch, Regenerative Medicine and Stem Cells, Centraal Diagnostisch Laboratorium, Programmabureau Zorg van Morgen, Child Health, Onderzoek Vrouw Hart & Vaatziekten

Θεματικοί όροι: sex differences, Physiology, endothelial-mesenchymal transition, Journal Article, Cardiology and Cardiovascular Medicine, multiomics, acute coronary syndrome, plaque, atherosclerotic

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/469395

Sex chromosomes and cardiovascular disease

Συγγραφείς: Spiering, Anna E, Groenheide, Phebe J, Mokry, Michal, Onland-Moret, N Charlotte, Civelek,Mete, Reue,Karen, Diez Benavente, Ernest, den Ruijter, Hester M, Experimentele Afd. Cardiologie 1, Circulatory Health, Cancer, Onderzoek Beeld, CDL Onderzoek Pasterkamp, Child Health, Data gedreven innovatie, JC onderzoeksprogramma Cardiovascular Health, Onderzoek Vrouw Hart & Vaatziekten

Θεματικοί όροι: sex differences, cardiovascular disease, Epidemiology, sex chromosomes, Cardiology and Cardiovascular Medicine

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/465757

Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease

Συγγραφείς: von Scheidt,Moritz, Adkar,Shaunak S, Krefting,Johannes, Hoermann,Gregor, Meggendorfer,Manja, Bauer,Sabine, Mitchell,Shaneice, Pugach,Irina, Friess,Christian, Ma,Angela, Hao,Ke, Steigerwald,Sophia, Wahle,Maria, Kessler,Thorsten, Schwab,Marius, Voll,Felix, Mokry, Michal, Sofokleous,Charalampos, Palm, Kaylin C A, Bongiovanni,Dario, Fleig,Julia, Oldenbuettel,Lilith, Chen,Zhifen, Hecker,Judith S, Bassermann,Florian, Maegdefessel,Lars, Graw,Matthias, Ruusalepp,Arno, Hilgendorf,Ingo, Leuschner,Florian, Sager,Hendrik B, Heimlich,J Brett, Koenig,Wolfgang, Cremer,Sebastian, Leistner,David M, Abplanalp,Wesley T, Dimmeler,Stefanie, Zeiher,Andreas M, van der Laan, Sander W, Pasterkamp, Gerard, Braun,Christian, Jaiswal,Siddhartha, Kovacic,Jason C, Kern,Wolfgang, Haferlach,Claudia, Mann,Matthias, Cassese,Salvatore, Kastrati,Adnan, Haferlach,Torsten, Leeper,Nicholas J, Björkegren,Johan L M, Schunkert,Heribert, CDL Onderzoek Pasterkamp, Experimentele Afd. Cardiologie 1, Child Health, Circulatory Health, Centraal Diagnostisch Laboratorium

Θεματικοί όροι: Clonal haematopoiesis of indeterminate potential, Inflammation, Aging, TET2, LDLR, Atherosclerotic cardiovascular disease, Macrophages, Journal Article, Mortality, Cardiovascular disease, Cardiology and Cardiovascular Medicine, Coronary artery disease

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/467520

A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease

Συγγραφείς: Shojaei Jeshvaghani,Zahra, Argmann,Carmen, de Vries, Maaike H, van Es, Johan H, Collen,Lauren V, Kotlarz,Daniel, Sveen,Mia, Comella,Phillip H, Snapper,Scott B, Klein,Christoph, Schadt,Eric E, Clevers, Hans, Mokry, Michal, Kuijk, Ewart, Nieuwenhuis, Edward, MDL onderzoek 1, Cancer, Infection & Immunity, Regenerative Medicine and Stem Cells, Hubrecht Institute with UMC, CMM, CDL Onderzoek Pasterkamp, Experimentele Afd. Cardiologie 1, Child Health, Circulatory Health, Cellular disease models 1, Onderzoek

Θεματικοί όροι: VEO-IBD, inflammation, IBD, Taverne, Journal Article, intestinal epithelium, organoids

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/468523

Enhancing cardiomyocyte reprogramming efficiency by targeting cellular senescence is mediated via Rb1 gene

Συγγραφείς: Fang, Juntao, Yang, Qiangbing, Maas, Renée G.C., Vader, Pieter, Mokry, Michal, van den Dungen, Noortje A.M., Qian,Li, Xiao,Junjie, Schiffelers, Raymond, Lei, Zhiyong, Sluijter, Joost P.G., Cardiologie, Experimentele Afd. Cardiologie 1, CDL Staf Research, CDL Nanomedicine, Experimentele Afd. Cardiologie 2, Circulatory Health, CDL Cluster Onderzoek en Onderwijs, CDL Poli WKZ, CDL Onderzoek Pasterkamp, Child Health, CDL Research analisten, Cancer, Centraal Diagnostisch Laboratorium, Regenerative Medicine and Stem Cells, Onderzoek Cardiovasculair Reg. Med.

Θεματικοί όροι: Direct cardiac reprogramming, Medicine (miscellaneous), Molecular Medicine, Cell Biology, RB1, Senescence, Biochemistry, Genetics and Molecular Biology (miscellaneous)

Περιγραφή αρχείου: text/plain

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/469057

The immune system in cardiovascular diseases:from basic mechanisms to therapeutic implications

Συγγραφείς: Wang,Xiaoyan, Chen,Liming, Wei, Jianming, Zheng,Hao, Zhou,Ning, Xu,Xinjie, Deng,Xin, Liu,Tao, Zou,Yunzeng, CDL Onderzoek Pasterkamp

Θεματικοί όροι: Adaptive Immunity/genetics, Cardiovascular Diseases/immunology, Cancer Research, Signal Transduction/immunology, Inflammasomes/immunology, Genetics, Journal Article, Animals, Humans, Immunity, Innate/genetics, Immunotherapy, Review

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/466271

Technical and legal aspects of federated learning in bioinformatics:applications, challenges and opportunities

Συγγραφείς: Malpetti,Daniele, Scutari,Marco, Gualdi,Francesco, van Setten, Jessica, van der Laan, Sander, Haitjema, Saskia, Lee,Aaron Mark, Hering,Isabelle, Mangili,Francesca, Onderzoek Precision medicine, Circulatory Health, CDL Onderzoek Pasterkamp, CDL Cluster Onderzoek en Onderwijs, CDL Cluster Speciële Diagnostiek

Θεματικοί όροι: Journal Article, Review

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/468712

Insights, opportunities, and challenges provided by large cell atlases

Συγγραφείς: Hemberg,Martin, Marini,Federico, Ghazanfar,Shila, Al Ajami,Ahmad, Abassi,Najla, Anchang,Benedict, Benayoun,Bérénice A., Cao,Yue, Chen,Ken, Cuesta-Astroz,Yesid, DeBruine,Zachary, Dendrou,Calliope A., De Vlaminck,Iwijn, Imkeller,Katharina, Korsunsky,Ilya, Lederer,Alex R., Li,Jessica Jingyi, Meysman,Pieter, Miller,Clint L., Mullan,Kerry A., Ohler,Uwe, Panwar,Pratibha, Patikas,Nikolaos, Schuck,Jonas, Siu,Jacqueline H.Y., Triche,Timothy J., Tsankov,Alex, van der Laan, Sander W., Yajima,Masanao, Yang,Jean, Zanini,Fabio, Jelic,Ivana, CDL Onderzoek Pasterkamp, Circulatory Health

Θεματικοί όροι: Genetics, Cell Biology, Ecology, Evolution, Behavior and Systematics

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/468109

Human colon stem cells are the predominant epithelial responders to bacterial antigens

Συγγραφείς: De Vries, Maaike H, Meddens, Claartje A, Hijma,Hemme J, Berrens,Anne-Claire, Jansen, Suze A, Kooiman,Berend A P, Snapper,Scott, Clevers, Hans, Mokry, Michal, Kuijk, Ewart W, Nieuwenhuis, Edward E S, MDL onderzoek 1, Cancer, Infection & Immunity, Regenerative Medicine and Stem Cells, Arts-assistenten Kinderen, Child Health, Cluster B, CMM, Hubrecht Institute with UMC, CDL Onderzoek Pasterkamp, Experimentele Afd. Cardiologie 1, Circulatory Health, Cellular disease models 1, Onderzoek

Θεματικοί όροι: intestinal stem cells, WNT pathway, inflammatory bowel disease, immune regulation, Immunology, Journal Article, Immunology and Allergy, intestinal epithelium, innate immunity

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/468148

Combination of antithrombin and soluble thrombomodulin for early prediction of sepsis-Induced disseminated intravascular coagulation

Συγγραφείς: Zeng,Huan, Wei, Jianming, Zeng,Jiujiang, Sun,Yuexi, Wang,Mengmeng, Dai,Guoxing, Song,Yanli, CDL Onderzoek Pasterkamp

Θεματικοί όροι: Antithrombin, Sepsis, Soluble Thrombomodulin, Journal Article, Disseminated intravascular coagulation (DIC)

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/467931

Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of the RNA sensor MDA5 in atherosclerosis

Συγγραφείς: Weldy,Chad S, Li,Qin, Monteiro,João P, Peters, Tim S, Guo,Hongchao, Galls,Drew, Gu,Wenduo, Cheng,Paul P, Ramste,Markus, Li,Daniel, Palmisano,Brian T, Sharma,Disha, Worssam,Matthew D, Zhao,Quanyi, Bhate,Amruta, Kundu,Ramendra K, Nguyen,Trieu, Mokry, Michal, Miller,Clint L, van der Laan, Sander W, Li,Jin Billy, Quertermous,Thomas, CDL Onderzoek Pasterkamp, Brain, Experimentele Afd. Cardiologie 1, Child Health, Circulatory Health

Θεματικοί όροι: Journal Article

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/467637

Candidate Biomarkers YES1, Troponin I, Lactate, and Ammonia for Evaluation of Cardiac Function Post Hypothermic Oxygenated Perfusion

Συγγραφείς: Ballan, Elisa M, Vervoorn, Mats T, Kaffka Genaamd Dengler, Selma E, Marsman, Judith, Mishra, Mudit, van Ginneken,Ilona M L J, van der Kraak,Petra, Vos, Annelotte, de Jager, Saskia C A, Sluijter, Joost P G, Doevendans, Pieter A, Mokry, Michal, van der Kaaij, Niels P, Innovatie CTC, Arts Assistenten CTC, Onderzoek Precision medicine, Experimentele Afd. Cardiologie 2, Pathologie Pathologen staf, Circulatory Health, Infection & Immunity, Onderzoek Cardiovasculair Reg. Med., Regenerative Medicine and Stem Cells, Team Medisch, CDL Onderzoek Pasterkamp, Experimentele Afd. Cardiologie 1, Child Health, CTC

Θεματικοί όροι: ex vivo heart preservation, Biomaterials, hypothermic machine perfusion, HOPE, Biophysics, Biomedical Engineering, biomarkers, Bioengineering, cardiac function, heart transplant, cardiac graft

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/465616

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Συγγραφείς: Smit,Roelof A J, Wade,Kaitlin H, Hui,Qin, Arias,Joshua D, Yin,Xianyong, Christiansen,Malene R, Yengo,Loic, Preuss,Michael H, Nakabuye,Mariam, Rocheleau,Ghislain, Graham,Sarah E, Buchanan,Victoria L, Chittoor,Geetha, Graff,Marielisa, Guindo-Martínez,Marta, Lu,Yingchang, Marouli,Eirini, Sakaue,Saori, Spracklen,Cassandra N, Vedantam,Sailaja, Wilson,Emma P, Chen,Shyh-Huei, Ferreira,Teresa, Ji,Yingjie, Karaderi,Tugce, Lüll,Kreete, Machado,Moara, Malden,Deborah E, Medina-Gomez,Carolina, Moore,Amy, Rüeger,Sina, Akiyama,Masato, Allison,Matthew A, Alvarez,Marcus, Andersen,Mette K, Appadurai,Vivek, Arbeeva,Liubov, Bartell,Eric, Bhaskar,Seema, Bielak,Lawrence F, Bis,Joshua C, Bollepalli,Sailalitha, Hemerich, Daiane, van der Laan, Sander W, van Setten, Jessica, Asselbergs, Folkert W, de Borst, Gert J, de Kleijn, Dominique P V, Kraaijeveld, Adriaan, van der Harst, Pim, 23andMe Research Team, CDL Onderzoek Pasterkamp, Circulatory Health, Onderzoek Precision medicine, Team Medisch, Zorgeenheid Vaatchirurgie Medisch, Regenerative Medicine and Stem Cells, DHL-Bedrijfsvoering

Θεματικοί όροι: General Biochemistry,Genetics and Molecular Biology, Journal Article, General Medicine

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/466991

Uncovering leading compounds for alzheimer's disease treatment:mendelian randomization and virtual screening insights into plasma protein modulation

Συγγραφείς: Sun,Xiaohan, Hu,Xiaofei, Wei, Jianming, An,Haoyu, CDL Onderzoek Pasterkamp

Συνεισφορές: CDL Onderzoek Pasterkamp

Θεματικοί όροι: Alzheimer Disease/genetics, Blood Proteins/genetics, Journal Article, Humans, Genetic Predisposition to Disease, Mendelian Randomization Analysis, Genome-Wide Association Study

Περιγραφή αρχείου: text/plain; application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/461060

A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis

Συγγραφείς: Asare,Yaw, Yan,Guangyao, Schlegl,Christina, Prestel,Matthias, van der Vorst,Emiel P C, Teunissen,Abraham J P, Aronova,Arailym, Tosato,Federica, Naser,Nawraa, Caputo,Julio, Prevot,Geoffrey, Azzun,Anthony, Wefers,Benedikt, Wurst,Wolfgang, Schneider,Melanie, Forne,Ignasi, Bidzhekov,Kiril, Naumann,Ronald, van der Laan, Sander W, Brandhofer,Markus, Cao,Jiayu, Roth,Stefan, Malik,Rainer, Tiedt,Steffen, Mulder,Willem J M, Imhof,Axel, Liesz,Arthur, Weber,Christian, Bernhagen,Jürgen, Dichgans,Martin, CDL Onderzoek Pasterkamp, Circulatory Health

Συνεισφορές: CDL Onderzoek Pasterkamp, Circulatory Health

Θεματικοί όροι: Immunology, cis-regulatory element, stroke, nanobiologics, Infectious Diseases, NLRP3, inflammasome, inflammation, HDAC9, therapeutics, Journal Article, GWAS, Immunology and Allergy, atherosclerosis

Περιγραφή αρχείου: text/plain; application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/460511

Disturbed Flow Induces Reprogramming of Endothelial Cells to Immune-like and Foam Cells under Hypercholesterolemia during Atherogenesis

Συγγραφείς: Park,Christian, Baek,Kyung In, Hung,Ruei-Chun, Choi,Leandro, Jeong,Kiyoung, Kim,Paul, Jahng,Andrew Keunho, Kim,Jung Hyun, Kim,Yerin, Meselhe,Mostafa, Kannan,Ashwin, Chou,Chien-Ling, Kang,Dong Won, Song,Eun Ju, Bowman-Kirigin,Jay Aaron, Clark,Michael David, van der Laan, Sander W, Pasterkamp, Gerard, Villa-Roel,Nicolas, Panitch,Alyssa, Jo,Hanjoong, CDL Onderzoek Pasterkamp, Circulatory Health, Centraal Diagnostisch Laboratorium

Συνεισφορές: CDL Onderzoek Pasterkamp, Circulatory Health, Centraal Diagnostisch Laboratorium

Θεματικοί όροι: Endothelial-to-immune cell-like transition, Physiology, Physiology (medical), Flow-induced reprogramming of endothelial cells (FIRE), Taverne, Journal Article, Endothelial-to-foam cell-like transition, Disturbed Flow, Atherosclerosis, Cardiology and Cardiovascular Medicine

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://utrecht-main-prod.atmire.com/handle/1874/461155
https://dspace.library.uu.nl/handle/1874/461155
https://dspace.library.uu.nl/handle/1874/468508

Computational Modeling Predicts Benefits of Proefferocytic Therapy in Human Atherosclerosis

Συγγραφείς: Jarr,Kai-Uwe, Palm, Kaylin C A, Pasterkamp, Gerard, Mokry, Michal, Leeper,Nicholas J, Centraal Diagnostisch Laboratorium, Circulatory Health, Experimentele Afd. Cardiologie 1, CDL Onderzoek Pasterkamp, Child Health

Θεματικοί όροι: efferocytosis, Physiology (medical), computer simulation, atherosclerosis, Cardiology and Cardiovascular Medicine, cardiovascular diseases

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/466989

Proteomic profiling reveals a higher presence of glycolytic enzymes in human atherosclerotic lesions with unfavourable histological characteristics

Συγγραφείς: Palm, Kaylin C A, Yin,Xiaoke, Baig,Ferheen, Theofilatos,Konstantinos, van der Laan, Sander W, de Borst, Gert J, de Kleijn, Dominique P V, Wojta,Johann, Stojkovic,Stefan, Mayr,Manuel, den Ruijter, Hester M, Pasterkamp, Gerard, Diez Benavente, Ernest, Mokry, Michal, CDL Onderzoek Pasterkamp, Circulatory Health, Zorgeenheid Vaatchirurgie Medisch, Regenerative Medicine and Stem Cells, Onderzoek Vrouw Hart & Vaatziekten, Centraal Diagnostisch Laboratorium, Experimentele Afd. Cardiologie 1, Child Health

Θεματικοί όροι: Proteomics, Multi-omics, Metabolism, Physiology, Physiology (medical), Atherosclerosis, Cardiovascular disease, Cardiology and Cardiovascular Medicine, Glycolysis

Περιγραφή αρχείου: application/pdf

Σύνδεσμος πρόσβασης: https://dspace.library.uu.nl/handle/1874/466299