Inhibiting translation elongation by reducing eIF5A activity induces feedback inhibition of initiation, limiting tumour cell proliferation

Authors: Sfakianos, AP, Raven, RM, Smith, T, Sun, X-M, Mulroney, TE, Pizzinga, M, Dezi, V, Tenor, AR, Stoneley, M, Cole, CH, Al-Doori, K, Nur, HA, Pennie, RL, Powley, I, Officer-Jones, L, Sawarkar, R, Turner, M, MacFarlane, M, Sansom, OJ, Bushell, M, Le Quesne, J, Harvey, RF, Willis, AE

Source: Nat Commun

Subject Terms: Feedback, Physiological, Eukaryotic Initiation Factor-2, Peptide Chain Elongation, Translational, RNA-Binding Proteins, Eukaryotic Translation Initiation Factor 5A, Article, Mitochondria, Peptide Initiation Factors, Cell Line, Tumor, Neoplasms, Protein Biosynthesis, Humans, Phosphorylation, Peptide Chain Initiation, Translational, Cell Proliferation, Signal Transduction

Access URL: https://pubmed.ncbi.nlm.nih.gov/41390489
https://pmc.ncbi.nlm.nih.gov/articles/PMC12749925/
https://doi.org/10.1038/s41467-025-66531-z
https://pubmed.ncbi.nlm.nih.gov/41390489/

Correction: Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1

Authors: Cobbold, L. C.^Aff1, Wilson, L. A.^Aff1, Sawicka, K.^Aff1, King, H. A.^Aff1, Kondrashov, A. V.^Aff1, Spriggs, K. A.^Aff1, Bushell, M.^Aff1, Willis, A. E.^{Aff1, IDs41388024031457_cor8}

Source: Oncogene. 43(42):3137-3138

Emerging Treatment Strategies for Impetigo in Endemic and Nonendemic Settings: A Systematic Review

Authors: Gahlawat, G, Tesfaye, W, Bushell, M, Abrha, S, Peterson, GM, Mathew, C, Sinnollareddy, M, McMillan, F, Samarawickrema, I, Calma, T, Chang, AY, Engelman, D, Steer, A, Thomas, J

Source: Clinical Therapeutics. 43:986-1006

Subject Terms: Staphylococcus aureus, group A Streptococcus, MDA, impetigo, Impetigo, drug therapy, Anti-Bacterial Agents, 3. Good health, Ointments, 03 medical and health sciences, 3004 Pharmacology, Treatment Outcome, 0302 clinical medicine, systematic review, 2736 Pharmacology (medical), Humans, Child, RCT

Access URL: http://www.clinicaltherapeutics.com/article/S0149291821002083/pdf
https://pubmed.ncbi.nlm.nih.gov/34053699
https://api.library.uq.edu.au/view/UQ:7c2bca1
https://espace.library.uq.edu.au/view/UQ:7c2bca1

Cannabinoids in integumentary wound care : a systematic review of emerging preclinical and clinical evidence

Authors: Niyangoda, D., Muayad, M., Tesfaye, W., Bushell, M., Ahmad, D., Samarawickrema, I., Sinclair, Justin (R19074), Kebriti, S., Maida, V., Thomas, J.

Subject Terms: XXXXXX - Unknown

File Description: print

Relation: Pharmaceutics--1999-4923-- Vol. 16 Issue. 8 No. 1081 pp: -

Availability: https://doi.org/10.3390/pharmaceutics16081081
https://hdl.handle.net/1959.7/uws:78908

Mass drug administration campaigns for scabies and impetigo: protocol for a systematic review and meta-analysis.

Authors: Ghosh, P, Tesfaye, W, Manandhar, A, Calma, T, Bushell, M, Oguoma, VM, Kosari, S, McMillan, F, Peterson, G, Thomas, J

Subject Terms: 3213 Paediatrics, Australia, Humans, Impetigo, Mass Drug Administration, Meta-Analysis as Topic, Prospective Studies, Scabies, Systematic Reviews as Topic

File Description: Electronic-eCollection; application/pdf

Relation: BMJ Paediatr Open; BMJ Paediatr Open, 2021, 5, (1), pp. e001132; http://hdl.handle.net/10453/176152

Availability: http://hdl.handle.net/10453/176152

Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation

Authors: Kanellos, G., Giacomelli, C., Raven, A., Vlahov, N., Jin, H., Herviou, P., Malla, S. B., Nasreddin, N., Centeno, P. P., Alexandrou, C., Gilroy, K., Baird, R. L., Pennel, K., Munro, J., Waldron, J. A., Hall, H., Officer-Jones, L., Bryson, S., Strathdee, D., Lilla, S., Zanivan, S., Morrison, V., Nixon, C., Ridgway, R. A., Miller, C., Knight, J. R. P., Campbell, A. D., Dunne, P. D., Le Quesne, J., Edwards, J., Park, P. J., Bushell, M., Sansom, O. J.

Contributors: Division of Cancer Sciences, University of Manchester, Manchester, UK.

File Description: application/pdf

Relation: https://christie.openrepository.com/handle/10541/628419; Nature Genetics

Availability: https://doi.org/10.1038/s41588-025-02408-7
https://christie.openrepository.com/handle/10541/628419

Changing the rules of the game for future agriculture, The University Innovation Centre (UIC) model

Authors: Grieve, B., Bushell, M., Lant, M., Georghiou, L., Malik, K.

Source: PICMET '09 - 2009 Portland International Conference on Management of Engineering & Technology Management of Engineering & Technology, 2009. PICMET 2009. Portland International Conference on. :288-298 Aug, 2009

Relation: PICMET '09 - 2009 Portland International Conference on Management of Engineering & Technology

Variable Ionizing Radiation Pulse Shape At The Aurora

Authors: Bushell, M., Fleetwood, R., Merkel, G., Smith, M.

Source: Eighth IEEE International Conference on Pulsed Power Pulsed Power Conference, 1991. Digest of Technical Papers. Eighth IEEE International. :826-829 1991

Relation: 1991 Eighth IEEE International Conference on Pulsed Power

eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation

Authors: Schmidt T, Dabrowska A, Waldron JA, Hodge K, Koulouras G, Gabrielsen M, Munro J, Tack DC, Harris G, McGhee E, Scott D, Carlin L, Huang D, Le Quesne J, Zanivan S, Wilczynska A, Bushell M

Relation: urn:ISSN; Nucleic Acids Res; http://purl.org/net/epubs/series/1721; ISIS (1984- ); Science and Technology Facilities Council (2007- ); http://purl.org/net/epubs/work/53885309

Availability: http://purl.org/net/epubs/work/53885309

In situ microwave ionized air chemistry measurements

Authors: Smith, R.S., Bushell, M., Fleetwood, R., Merkel, G., Smith, M.

Source: IEEE Transactions on Nuclear Science IEEE Trans. Nucl. Sci. Nuclear Science, IEEE Transactions on. 39(6):1935-1942 Dec, 1992

Bremsstrahlung risetime shortening by diode geometry reconfiguration

Authors: Bushell, M., Fleetwood, R., Judy, D., Merkel, G., Smith, M., Nguyen, K., Weidenheimer, D.

Source: IEEE Transactions on Nuclear Science IEEE Trans. Nucl. Sci. Nuclear Science, IEEE Transactions on. 39(6):2070-2077 Dec, 1992

Translational Repression and eIF4A2 Activity Are Critical for MicroRNA-Mediated Gene Regulation

Authors: Meijer, H. A., Kong, Y. W., Lu, W. T., Wilczynska, A., Spriggs, R. V., Robinson, S. W., Godfrey, J. D., Willis, A. E., Bushell, M.

Source: Science, 2013 Apr 01. 340(6128), 82-85.

Access URL: http://dx.doi.org/10.1126/science.1231197

Aschiphasmatidae, Heteropteryginae and Lonchodinae in the Forestry Research Centre, Sepilok, Sabah

Authors: Bragg, P E, Bushell, M L T

Contributors: BioStor

Source: 11:1-4

Access URL: http://www.biodiversitylibrary.org/part/211212

MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.

Authors: Knight, JRP, Alexandrou, C, Skalka, GL, Vlahov, N, Pennel, K, Officer, L, Teodosio, A, Kanellos, G, Gay, DM, May-Wilson, S, Smith, EM, Najumudeen, AK, Gilroy, K, Ridgway, RA, Flanagan, DJ, Smith, RCL, McDonald, L, MacKay, C, Cheasty, A, McArthur, K, Stanway, E, Leach, JD, Jackstadt, R, Waldron, JA, Campbell, AD, Vlachogiannis, G, Valeri, N, Haigis, KM, Sonenberg, N, Proud, CG, Jones, NP, Swarbrick, ME, McKinnon, HJ, Faller, WJ, Le Quesne, J, Edwards, J, Willis, AE, Bushell, M, Sansom, OJ

Contributors: Valeri, Nicola

File Description: Print-Electronic; application/pdf

Relation: Cancer discovery, 2020; https://repository.icr.ac.uk/handle/internal/4389

Availability: https://repository.icr.ac.uk/handle/internal/4389

Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease

Authors: Chernova, T, Sun, X M, Powley, I R, Galavotti, S, Grosso, S, Murphy, F A, Miles, G J, Cresswell, L, Antonov, A V, Bennett, J, Nakas, A, Dinsdale, D, Cain, K, Bushell, M, Willis, A E, MacFarlane, M

Source: Cell Death Differ

Subject Terms: Male, Mesothelioma, 0301 basic medicine, Lung Neoplasms, Microbiology, Genomic Instability, 03 medical and health sciences, Oxygen Consumption, 0302 clinical medicine, Tumor Suppressor Protein p14ARF, Tumor Cells, Cultured, Cyclin-Dependent Kinase Inhibitor p18, Humans, Cyclin-Dependent Kinase Inhibitor p16, Aged, Original Paper, Neurofibromin 2, Principal Component Analysis, Mesothelioma, Malignant, Middle Aged, 3. Good health, Tandem Repeat Sequences, Metabolome, Female, Tumor Suppressor Protein p53, Transcriptome

File Description: application/pdf; text

Access URL: https://www.nature.com/articles/cdd2015165.pdf
https://pubmed.ncbi.nlm.nih.gov/26891694
https://eprints.gla.ac.uk/178421/1/178421.pdf
https://strathprints.strath.ac.uk/83540/

European Red List of Grasshoppers, Crickets and Bush-crickets

Authors: Hochkirch A., Nieto A., García Criado M., Cálix M., Braud Y., Buzzetti F. M., Chobanov D., Odé B., Presa Asensio J. J., Willemse L., Zuna-Kratky T., Barranco Vega P., Bushell M., Clemente M. E., Correas J. R., Dusoulier F., Ferreira S., Fontana P., García M. D., Heller K-G, Iorgu I. Ș., Ivković S., Kati V., Kleukers R., Krištín A., Lemonnier-Darcemont M., Lemos P., Massa B., Monnerat C., Papapavlou K. P., Prunier F., Pushkar T., Roesti C., Rutschmann F., Şirin D., Skejo J., Szövényi G., Tzirkalli E., Vedenina V., Barat Domenech J., Barros F., Cordero Tapia P. J., Defaut B., Fartmann T., Gomboc S., Gutiérrez-Rodríguez J., Holuša J., Illich I., Karjalainen S., Kočárek P., Korsunovskaya O., Liana A., López H., Morin D., Olmo-Vidal J. M., Puskás G., Savitsky V., Stalling T., Tumbrinck J.

Contributors: Hochkirch, A., Nieto, A., García Criado, M., Cálix, M., Braud, Y., Buzzetti, F., Chobanov, D., Odé, B., Presa Asensio, J., Willemse, L., Zuna-Kratky, T., Barranco Vega, P., Bushell, M., Clemente, M., Correas, J., Dusoulier, F., Ferreira, S., Fontana, P., García, M., Heller, K., Iorgu, I., Ivković, S., Kati, V., Kleukers, R., Krištín, A., Lemonnier-Darcemont, M., Lemos, P., Massa, B., Monnerat, C., Papapavlou, K., Prunier, F., Pushkar, T., Roesti, C., Rutschmann, F., Şirin, D., Skejo, J., Szövényi, G., Tzirkalli, E., Vedenina, V., Barat Domenech, J., Barros, F., Cordero Tapia, P., Defaut, B., Fartmann, T., Gomboc, S., Gutiérrez-Rodríguez, J., Holuša, J., Illich, I., Karjalainen, S., Kočárek, P., Korsunovskaya, O., Liana, A., López, H., Morin, D., Olmo-Vidal, J., Puskás, G., Savitsky, V., Stalling, T., Tumbrinck, J.

Subject Terms: Insecta, Orthoptera, Red List, Europe, Settore AGR/11 - Entomologia Generale E Applicata

Relation: numberofpages:94; http://hdl.handle.net/10447/247753

Availability: http://hdl.handle.net/10447/247753
https://doi.org/10.2779/356312

European red list of grasshoppers, crickets and bush-crickets

Authors: Hochkirch, A., Nieto, A., García Criado, M., Cálix, M., Braud, Y., Buzzetti, F. M., Chobanov, D., Odé, B., Presa Asensio, J. J., Willemse, L., Zuna Kratky, T., Barranco Vega, P., Bushell, M., Clemente, M. E., Correas, J. R., Dusoulier, F., Ferreira, S., Fontana, Paolo, García, M. D., Heller, K. G., Iorgu, I. Ș., Ivković, S., Kati, V., Kleukers, R., Krištín, A., Lemonnier Darcemont, M., Lemos, P., Massa, B., Monnerat, C., Papapavlou, K. P., Prunier, F., Pushkar, T., Roesti, C., Rutschmann, F., Şirin, D., Skejo, J., Szövényi, G., Tzirkalli, E., Vedenina, V., Barat Domenech, J., Barros, F., Cordero Tapia, P. J., Defaut, B., Fartmann, T., Gomboc, S., Gutiérrez Rodríguez, J., Holuša, J., Illich, I., Karjalainen, S., Kočárek, P., Korsunovskaya, O., Liana, A., López, H., Morin, D., Olmo Vidal, J. M., Puskás, G., Savitsky, V., Stalling, T., Tumbrinck, J.

Contributors: Hochkirch, A., Nieto, A., García Criado, M., Cálix, M., Braud, Y., Buzzetti, F.M., Chobanov, D., Odé, B., Presa Asensio, J.J., Willemse, L., Zuna Kratky, T., Barranco Vega, P., Bushell, M., Clemente, M.E., Correas, J.R., Dusoulier, F., Ferreira, S., Fontana, P., García, M.D., Heller, K.G., Iorgu, I.Ș., Ivković, S., Kati, V., Kleukers, R., Krištín, A., Lemonnier Darcemont, M., Lemos, P., Massa, B., Monnerat, C., Papapavlou, K.P., Prunier, F., Pushkar, T., Roesti, C., Rutschmann, F., Şirin, D., Skejo, J., Szövényi, G., Tzirkalli, E., Vedenina, V., Barat Domenech, J., Barros, F., Cordero Tapia, P.J., Defaut, B., Fartmann, T., Gomboc, S., Gutiérrez Rodríguez, J., Holuša, J., Illich, I., Karjalainen, S., Kočárek, P., Korsunovskaya, O., Liana, A., López, H., Morin, D., Olmo Vidal, J.M., Puskás, G., Savitsky, V., Stalling, T., Tumbrinck, J.

Subject Terms: Settore AGR/11 - ENTOMOLOGIA GENERALE E APPLICATA

Relation: info:eu-repo/semantics/altIdentifier/isbn/9789279617515; numberofpages:86 p.; https://hdl.handle.net/10449/37510

Availability: https://hdl.handle.net/10449/37510
https://doi.org/10.2779/60944
https://portals.iucn.org/library/sites/library/files/documents/RL-4-021.pdf

Selective embedment of silver nanocrystals into spatially segregated domains in thin polymer films for controlled fabrication of functional nanocomposites

Authors: Bushell, M. (Michael), Ianoul, A.I. (Anatoli)

Source: RSC Advances vol. 9 no. 33, pp. 19131-19141

File Description: application/pdf

Relation: https://ir.library.carleton.ca/pub/24724

Availability: https://ir.library.carleton.ca/pub/24724
https://doi.org/10.1039/c9ra02490e

The role of microRNA in nutritional control

Authors: Nolte-'t Hoen, E. N. M., Van Rooij, E., Bushell, M., Zhang, C.-Y., Dashwood, R. H., James, W. P. T., Harris, C., Baltimore, D.

Contributors: Infection & Immunity, dB&C I&I, Fertility & Reproduction, LS Celbiologie-Algemeen

Source: J Intern Med

Subject Terms: 0301 basic medicine, 0303 health sciences, General Medicine, metabolic control, Cell Communication, Prognosis, Article, 3. Good health, MicroRNAs, 03 medical and health sciences, nutrition, Nutrition Assessment, SDG 3 - Good Health and Well-being, Neoplasms, Taverne, Animals, Humans, pathology, signalling, development, miRNA

File Description: application/pdf

Access URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/joim.12372
https://pubmed.ncbi.nlm.nih.gov/25832550
https://pubmed.ncbi.nlm.nih.gov/25832550/
https://pmc.ncbi.nlm.nih.gov/articles/PMC12910441/
https://doi.org/10.1111/joim.12372
https://research-portal.uu.nl/en/publications/41c81e26-671b-426b-982c-5e6a760c6d3f
https://doi.org/10.1111/joim.12372
https://dspace.library.uu.nl/handle/1874/340810

LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

Authors: Sturge, J., Weir, J., Michael, T., Mura, M., Hopkins, T. G., Abd-Latip, N., Aboagye, E., Mauri, F., Jameson, C., Gabra, H., Bushell, M., Willis, A. E., Curry, E., Blagden, S. P.

Contributors: GlaxoSmithKline Services Unlimited, Wellbeing of Women

Source: Oncogene

Subject Terms: 0301 basic medicine, Biochemistry & Molecular Biology, CERVICAL-CANCER, RNA Processing, Messenger, Post-Transcriptional, Autoantigens, LARP1, SS-B Antigen, MESSENGER-RNA STABILITY, Mice, 03 medical and health sciences, MAMMALIAN-CELLS, Neoplasms, Animals, Humans, Neoplasm Invasiveness, RNA, Messenger, Neoplasm Metastasis, RNA Processing, Post-Transcriptional, Inbred BALB C, GENE-EXPRESSION, Genetics & Heredity, Mice, Inbred BALB C, 0303 health sciences, Science & Technology, TOR Serine-Threonine Kinases, BINDING PROTEINS, Cell Biology, SPECIMENS, 3. Good health, TARGET, Oncology, Ribonucleoproteins, Disease Progression, RNA, EARLY-STAGE, Original Article, Female, TRANSLATION, Life Sciences & Biomedicine, DECAY

File Description: application/pdf

Access URL: https://www.nature.com/articles/onc2014428.pdf
https://pubmed.ncbi.nlm.nih.gov/25531318
https://eprints.gla.ac.uk/177949/1/177949.pdf
https://ora.ox.ac.uk/objects/uuid:f53acfee-8c6b-4289-9814-db3db9a1def5
https://doi.org/10.1038/onc.2014.428
https://discovery-pp.ucl.ac.uk/id/eprint/1478373/