A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology

Συγγραφείς: Hanna Huber, Laia Montoliu-Gaya, Wagner S. Brum, Jakub Vávra, Yara Yakoub, Haley Weninger, Luisa Sophie Braun-Wohlfahrt, Joel Simrén, Mercé Boada, Agustín Ruiz, Amanda Cano, Adelina Orellana, Sergi Valero, Laia Cañada, Natalia Tantinya, Ana Belen Nogales, Pilar Sanz-Cartagena, Anna Dittrich, Ingmar Skoog, Millie Sander-Long, Clive Ballard, Megan Richards, Mary O’Leary, Frederikke Kragh Clemmensen, Hannah H. D. Wandall, Daniele Altomare, Valentina Cantoni, Erik Stomrud, Sebastian Palmqvist, Alberto Lleo, Daniel Alcolea, Maria Carmona Iragui, Aida Sanjuan Hernandez, Bessy Benejam, Laura Videla Toro, Alpana Singh, Marisa N. Denkinger, Anja Hviid Simonsen, Silke Kern, Anne Corbett, Juan Fortea, Lee Honigberg, Barbara Borroni, Oskar Hansson, Xavier Morató, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton

Πηγή: Nat Med
Nature medicine 32(2), 599-608 (2026). doi:10.1038/s41591-025-04080-0

Θεματικοί όροι: Male, Aged, 80 and over, Dried Blood Spot Testing: methods, tau Proteins: blood, Alzheimer Disease: diagnosis, tau Proteins, MAPT protein, human, Middle Aged, Alzheimer Disease: blood, Article, Neurofilament Proteins: blood, Alzheimer Disease: pathology, Biomarkers: blood, Neurofilament Proteins, Glial Fibrillary Acidic Protein, Humans, Biomarkers: cerebrospinal fluid, Female, Glial Fibrillary Acidic Protein: blood, Phosphorylation, neurofilament protein L, Biomarkers, Aged

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41491101
https://pubmed.ncbi.nlm.nih.gov/41491101/
https://doi.org/10.1038/s41591-025-04080-0
https://pmc.ncbi.nlm.nih.gov/articles/PMC12920126/
https://pub.dzne.de/record/285353

Medial temporal lobe atrophy in Down syndrome along the Alzheimer’s disease continuum

Συγγραφείς: Benjamin J Buehner, Alejandra O Morcillo-Nieto, Sara E Zsadanyi, Mateus Rozalem Aranha, José Enrique Arriola-Infante, Lídia Vaqué-Alcázar, Javier Arranz, Íñigo Rodríguez-Baz, Lucia Maure Blesa, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Nuria Bargalló, Sofía González-Ortiz, Sandra Giménez, Robin de Flores, Paul A Yushkevich, Daniel Alcolea, Olivia Belbin, Alberto Lleó, Maria Carmona-Iragui, Juan Fortea, Alexandre Bejanin

Πηγή: BRAIN
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Brain

Θεματικοί όροι: Male, Adult, neuroimaging, Amyloid beta-Peptides, Down syndrome, tau Proteins, Alzheimer's disease, Middle Aged, Magnetic Resonance Imaging, Temporal Lobe, medial temporal lobe, Cross-Sectional Studies, Alzheimer Disease, grey matter atrophy, Disease Progression, magnetic resonance imaging, Humans, Female, Down Syndrome, Atrophy, Biomarkers, Aged

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40243675
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19817

Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome

Συγγραφείς: Alejandra O. Morcillo‐Nieto, Mateus Rozalem‐Aranha, Lucia Maure‐Blesa, Íñigo Rodríguez‐Baz, José Enrique Arriola‐Infante, Maria Franquesa‐Mullerat, Sara E. Zsadanyi, Lídia Vaqué‐Alcázar, José Allende Parra, Zili Zhao, Javier Arranz, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Lucia Pertierra, Sandra Giménez, Daniel Alcolea, Olivia Belbin, Alberto Lleó, María Carmona‐Iragui, Juan Fortea, Alexandre Bejanin

Πηγή: Alzheimers Dement

Θεματικοί όροι: Male, Adult, Alzheimer Disease, Disease Progression, Humans, Brain, Female, Longitudinal Studies, Down Syndrome, Middle Aged, White Matter, Magnetic Resonance Imaging, Research Article

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/41639041
https://pmc.ncbi.nlm.nih.gov/articles/PMC12872401/
https://pubmed.ncbi.nlm.nih.gov/41639041/
https://doi.org/10.1002/alz.71157

Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum

Συγγραφείς: Maria Franquesa‐Mullerat, Alejandra O. Morcillo‐Nieto, José Enrique Arriola‐Infante, Sara E. Zsadanyi, Lídia Vaqué‐Alcázar, Mateus Rozalem‐Aranha, Javier Arranz, Íñigo Rodríguez‐Baz, Lucia Maure‐Blesa, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Sandra Giménez, Daniel Alcolea, Olivia Belbin, Alberto Lleó, María Carmona‐Iragui, Juan Fortea, Alexandre Bejanin

Πηγή: Alzheimers Dement
Alzheimers & Dementia
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)

Θεματικοί όροι: Male, Adult, arterial transit time, neuroimaging, brain perfusion, Down syndrome, Brain, Alzheimer's disease, Middle Aged, arterial spin labeling, Magnetic Resonance Imaging, Alzheimer Disease, Cerebrovascular Circulation, magnetic resonance imaging, Humans, Female, Spin Labels, Down Syndrome, Research Article, Aged

Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/40968330
https://pmc.ncbi.nlm.nih.gov/articles/PMC12445992/
https://doi.org/10.1002/alz.70581
https://pubmed.ncbi.nlm.nih.gov/40968330/
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=20471