Prediction of Local Infectious and Inflammatory Complications After Reconstructive Surgery of Aorta ; Прогнозирование локальных инфекционно-воспалительных осложнений при реконструктивных операциях на аорте

Authors: Oksana O. Grin, Natalia V. Beloborodova, Marina S. Grekova, Aliсa K. Pautova, Eduard R. Charchyan, Boris A. Akselrod, Olga V. Dymova, Lyubov I. Rizun, Alexander A. Eremenko, Maxim A. Babaev, О. О. Гринь, Н. В. Белобородова, М. С. Грекова, А. К. Паутова, Э. Р. Чарчян, Б. А. Аксельрод, О. В. Дымова, Л. И. Ризун, А. А. Еременко, M. А. Бабаев

Source: General Reanimatology; Том 21, № 1 (2025); 4-14 ; Общая реаниматология; Том 21, № 1 (2025); 4-14 ; 2411-7110 ; 1813-9779

Subject Terms: кардиохирургия, biomarkers, interleukin-6, aromatic microbial metabolites, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, cardiac surgery, биомаркеры, интерлейкин-6, ароматические метаболиты микробиоты, нейтрофильно-лимфоцитарный индекс, тромбоцитарно-лимфоцитарный индекс

File Description: application/pdf

Relation: https://www.reanimatology.com/rmt/article/view/2492/1907; https://www.reanimatology.com/rmt/article/view/2492/1914; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1065; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1066; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1067; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1068; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1069; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1070; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1071; https://www.reanimatology.com/rmt/article/downloadSuppFile/2492/1072; Попов Д. А. Послеоперационные инфекционные осложнения в кардиохирургии. Анналы хирургии. 2013; (5): 15–21.; Robich M. P., Sabik J. F. 3rd Houghtaling P. L., Kelava M., Gordon S., Blackstone E. H., Koch C. G. Prolonged effect of postoperative infectious complications on survival after cardiac surgery. Ann Thorac Surg. 2015; 99 (5): 1591–1599. DOI:10.1016/j.athoracsur.2014.12.037. PMID: 25686669.; Jenney A. W., Harrington G. A., Russo P. L., Spelman D. W. Cost of surgical site infections following coronary artery bypass surgery. ANZ J Surg. 2001; 71 (11): 662–664. DOI:10.1046/j.1445-1433.2001.02225.x. PMID: 11736828.; Jonkers D., Elenbaas T., Terporten P., Nieman F., Stobberingh E. Prevalence of 90-days postoperative wound infections after cardiac surgery. Eur J Cardiothorac Surg. 2003; 23 (1): 97–102. DOI:10.1016/s1010-7940(02)00662-0. PMID: 12493512.; Aljure O. D., Fabbro M. 2nd Cardiopulmonary bypass and inflammation: the hidden enemy. J Cardiothorac Vasc Anesth. 2019; 33 (2): 346–347. DOI:10.1053/j.jvca.2018.05.030. PMID: 30057250.; Paparella D., Yau T. M., Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update. Eur J Cardiothorac Surg. 2002; 21 (2): 232–244. DOI:10.1016/s1010-7940(01)01099-5. PMID: 11825729.; Maisat W., Yuki K. Narrative review of systemic inflammatory response mechanisms in cardiac surgery and immunomodulatory role of anesthetic agents. Ann Card Anaesth. 2023; 26 (2): 133–142. DOI:10.4103/aca.aca_147_22. PMID: 37706376.; Kraft F., Schmidt C., Van Aken H., Zarbock A. Inflammatory response and extracorporeal circulation. Best Pract Res Clin Anaesthesiol. 2015; 29 (2): 113–123. DOI:10.1016/j.bpa.2015.03.001. PMID: 26060024.; Jayakumar S., Khoynezhad A., Jahangiri M. Surgical site infections in cardiac surgery. Crit Care Clin. 2020; 36 (4): 581–592. DOI:10.1016/j.ccc.2020.06.006. PMID: 32892815.; Michalopoulos A., Geroulanos S., Rosmarakis E. S., Falagas M. E. Frequency, characteristics, and predictors of microbiologically documented nosocomial infections after cardiac surgery. Eur J Cardiothorac Surg. 2006; 29 (4): 456–460. DOI:10.1016/j.ejcts.2005.12.035. PMID: 16481186.; Kollef M. H., Sharpless L., Vlasnik J., Pasque C., Murphy D., Fraser V. J. The impact of nosocomial infections on patient outcomes following cardiac surgery. Chest. 1997; 112 (3): 666–675. DOI:10.1378/chest.112.3.666. PMID: 9315799.; Damavandi D. S., Javan M., Moshashaei H., Forootan M., Darvishi M. Microbial contamination after cardiac surgery in a hospital cardiac surgery ward. J Med Life. 2020; 13 (3): 342–348. DOI:10.25122/jml-2019-0071. PMID: 33072206.; Orita H., Shimanuki T., Fukasawa M., Inui K., Goto S., Washio M., Horikawa H. A clinical study of postoperative infections following open-heart surgery: occurrence and microbiological findings in 782 cases. Surg Today. 1992; 22 (3): 207–212. DOI:10.1007/BF00308824. PMID: 1392323.; Paternoster G., Guarracino F. Sepsis after cardiac surgery: from pathophysiology to management. J Cardiothorac Vasc Anesth. 2016; 30 (3): 773–780. DOI:10.1053/j.jvca.2015.11.009. PMID: 26947713.; Гринь О. О., Бабаев М. А., Грекова М. С., Котельникова Е. О., Исалова К. М., Еременко А. А. Предиктивная значимость гематологических индексов при реконструктивных операциях на аорте: проспективное наблюдательное исследование. Вестник интенсивной терапии им. А. И. Салтанова. 2024; 1: 82–93.; Нозокомиальная пневмония у взрослых: Российские национальные рекомендации. Под ред. акад. РАН Б. Р. Гельфанда; отв. ред. к. м. н., доцент Д. Н. Проценко, к. м. н., доцент Б. З. Белоцерковский. — 2-е изд., перераб. и доп. — М.: ООО «Издательство «Медицинское информационное агентство»; 2016: 176.; Smid J., Scherner M., Wolfram O., Groscheck T., Wippermann J., Braun-Dullaeus R. C. Cardiogenic causes of fever. Dtsch Arztebl Int. 2018; 115 (12): 193–199. DOI:10.3238/arztebl.2018.0193. PMID: 29642989.; Garibaldi R. A., Brodine S., Matsumiya S., Coleman M. Evidence for the non-infectious etiology of early postoperative fever. Infect Control. 1985; 6 (7): 273–277. DOI:10.1017/s0195941700061749. PMID: 3847403.; Livelli F. D. Jr., Johnson R. A., McEnany M.T., Sherman E., Newell J., Block P. C., DeSanctis R. W. Unexplained in-hospital fever following cardiac surgery. Natural history, relationship to postpericardiotomy syndrome, and a prospective study of therapy with indomethacin versus placebo. Circulation. 1978; 57 (5): 968–975. DOI:10.1161/01.cir.57.5.968. PMID: 346257.; Rhee C., Sax P. E. Evaluation of fever and infections in cardiac surgery patients. 2015; 19 (2): 143–153. DOI:10.1177/1089253214538524. PMID: 24958717.; Bateman R. M., Sharpe M. D., Jagger J. E., Ellis C. G., Solle-Volan J., Lopez-Rodrigez M., Herrera-Ramos E., et al. 36th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 15-18 March 2016. Crit Care. 2016; 20 (Suppl 2): 94. DOI:10.1186/s13054-016-1208-6. PMID: 27885969.; Verkkala K., Valtonen V., Järvinen A., Tolppanen E. M. Fever, leucocytosis and C-reactive protein after open-heart surgery and their value in the diagnosis of postoperative infections. Thorac Cardiovasc Surg. 1987; 35 (2): 78–82. DOI:10.1055/s-2007-1020201. PMID: 2440139.; Smith S. E., Muir J., Kalabalik-Hoganson J. Procalcitonin in special patient populations: guidance for antimicrobial therapy. Am J Health Syst Pharm. 2020; 77 (10): 745–758. DOI:10.1093/ajhp/zxaa089. PMID: 32340027.; Sharma P., Patel K., Baria K., Lakhia K., Malhotra A., Shah K., Patel S. Procalcitonin level for prediction of postoperative infection in cardiac surgery. Asian Cardiovasc Thorac Ann. 2016; 24 (4): 344–349. DOI:10.1177/0218492316640953. PMID: 27002098.; de la Varga-Martínez O., Martín-Fernández M., Heredia-Rodríguez M., Ceballos F., Cubero-Gallego H., Priede-Vimbela J. M., Bardají-Carrillo M., et al. Influence of renal dysfunction on the differential behaviour of procalcitonin for the diagnosis of postoperative infection in cardiac surgery. J Clin Med. 2022; 11 (24): 7274. DOI:10.3390/jcm11247274. PMID: 36555891.; Xie M., Chen Y. T., Zhang H., Zhang H. T., Pan K., Chen X. F., Xie X. L. Diagnostic value of procalcitonin and interleukin6 on early postoperative pneumonia after adult cardiac surgery: a prospective observational study. Heart Surg Forum. 2022; 25 (1): E020–E029. DOI:10.1532/hsf.4297. PMID: 35238309.; Sander M., von Heymann C., von Dossow V., Spaethe C., Konertz W. F., Jain U., Spies C. D. Increased interleukin-6 after cardiac surgery predicts infection. Anesth Analg. 2006; 102 (6): 1623–1629. DOI:10.1213/01.ane.0000215998.21739.48. PMID: 16717298.; Cremer J., Martin M., Redl H., Bahrami S., Abraham C., Graeter T., Haverich A., et al. Systemic inflammatory response syndrome after cardiac operations. Ann Thorac Surg. 1996; 61 (6): 1714–1720. DOI:10.1016/0003-4975(96)00055-0. PMID: 8651772.; Черневская Е. А., Гецина М. Л., Черпаков Р. А., Сорокина Е. А., Шабанов А. К., Мороз В. В., Белобородова Н. В. Сепсис-ассоциированные метаболиты и их биотрансформация кишечной микробиотой. Общая реаниматология. 2023; 19 (6): 4–12.; Beloborodova N., Pautova A., Grekova M., Yadgarov M., Grin O., Eremenko A., Babaev M. Microbiota metabolism failure as a risk factor for postoperative complications after aortic prosthetics. Biomedicines. 2023; 11 (5): 1335. DOI:10.3390/biomedicines11051335. PMID: 37239006.; Nguyen M., Stiel L., Guilloteau A., Bahr P. A., Masson D., Thomas C., Blot M., et al. Leukocyte cell population data in patients with cardiac surgery and cardiopulmonary bypass: a potential readily available tool to monitor immunity. Front Immunol. 2023; 13: 1101937. DOI:10.3389/fimmu.2022.1101937. PMID: 36741408.; Gibson P. H., Croal B. L., Cuthbertson B. H., Small G. R., Ifezulike A. I., Gibson G., Jeffrey R. R., et al. Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting. Am Heart J. 2007; 154 (5): 995–1002. DOI:10.1016/j.ahj.2007.06.043. PMID: 17967611.; King A. H., Schmaier A. H., Harth K. C., Kumins N. H., Wong V. L., Zidar D. A., Kashyap V. S., et al. Elevated neutrophillymphocyte ratio predicts mortality following elective endovascular aneurysm repair. J Vasc Surg. 2020; 72 (1): 129–137. DOI:10.1016/j.jvs.2019.10.058. PMID: 32037083.; Khalil C., Pham M., Sawant A. C., Sinibaldi E., Bhardwaj A., Ramanan T., Qureshi R., et al. Neutrophil-to-lymphocyte ratio predicts heart failure readmissions and outcomes in patients undergoing transcatheter aortic valve replacement. Indian Heart J. 2018; 70 Suppl 3 (Suppl 3): S313-S318. DOI:10.1016/j.ihj.2018.08.002. PMID: 30595282.; Zhu Y., Peng W., Zhen S., Jiang X. Postoperative neutrophilto-lymphocyte ratio is associated with mortality in adult patients after cardiopulmonary bypass surgery: a cohort study. Med Sci Monit. 2021; 27: e932954. DOI:10.12659/MSM.932954. PMID: 34565791.; https://www.reanimatology.com/rmt/article/view/2492

Availability: https://www.reanimatology.com/rmt/article/view/2492
https://doi.org/10.15360/1813-9779-2025-1-4-14

Comprehensive assessment of the systemic and local immunity, inflammatory factors and clinical indicators in patients with gastric cancer ; Комплексная оценка системного и локального иммунитета, факторов воспаления и клинических показателей у больных раком желудка. Злокачественные опухоли

Authors: G. G. Khakimova, A. A. Tryakin, T. N. Zabotina, Sh. G. Khakimova, Г. Г. Хакимова, А. А. Трякин, Т. Н. Заботина, Ш. Г. Хакимова

Source: Malignant tumours; Том 10, № 4 (2020); 5-15 ; Злокачественные опухоли; Том 10, № 4 (2020); 5-15 ; 2587-6813 ; 2224-5057

Subject Terms: тромбоцитарно‑лимфоцитарный индекс, cellular immunity, local immunity, subpopulation of lymphocytes, neutrophil‑ lymphocyte index, platelet‑lymphocyte index, клеточный иммунитет, локальный иммунитет, субпопуляция лимфоцитов, нейтрофильно‑лимфоцитраный индекс

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Relation: https://www.malignanttumors.org/jour/article/view/823/577; Бережная Н. М. Взаимодействие клеток системы иммунитета с другими компонентами микроокружения. Онкология. 2009; 1 (2): 86–93.; Mantovani A. et al. Tumor immunity: effector response to tumor and role of the microenvironment. Lancet 2008; 371 (9614): 771–83.; Тупицын Н. Н. Иммунофенотип рака молочнойжелезы. В кн.: Рак молочнойжелезы. Под ред. Н. Е. Кушлинского, С.М. Портного, К. П. Лактионова. М.: Издательство РАМН, 2005; с. 174–97.; Balch C., Riley L., Bae T. et al. Patterns of human tumor infiltrating lymphocytes in 120 human cancers. Arch Surg 1990; 125 (2): 200–5.; Galon J., Pages F. et al. Cancer classification using the immunoscore: a worldwide task force. J Transl Med 2012; 10: 205.; Zamarron B. F., Chen W. Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci. 2011; 7 (5): 651–658.; Ruffell B., DeNardo D. G., Affara N. I. et al. Lymphocytes in cancer development: polarization towards protumor immunity. Cytokine Growth Factor Rev. 2010; 21: 3–10.; Shen Z. Zhou S., Wang Y. et al. Higher intratumoral infiltrated Foxp3 + Treg numbers and Foxp3 + / C8 + ratio are associated with adverse prognosis in resectable gastric cancer. J Cancer Res Clin. Oncol. 2010; 136:1585–1595.; Mori M., Shuto K., Kosugi C. et al. An increase in the neutrophil to lymphocyte ratio during adjuvant chemotherapy indicates a poor prognosis in patients with stage II or III gastric cancer. BMC Cancer. 2018;18 (1):1261.; Passardi A., Scarpi E., Cavanna L. et al. Inflammatory indexes as predictors of prognosis and bevacizumab efficacy in patients with metastatic colorectal cancer. Oncotarget 2016;7 (22):33210–9. DOI:10.18632 / oncotarget. 8901.; Gunaldi M., Goksu S., Erdem D. et al. Prognostic impact of platelet / lymphocyte and neutrophil / lymphocyte ratios in patients with gastric cancer: a multicenter study. Int J Clin Exp Med. 2015;8 (4):5937–42.; Zheng X., Song X., Shao Y. et al. Prognostic role of tumor-infiltrating lymphocytes in gastric cancer: A meta-analysis. Oncotarget. 2017; 8. 10.18632 / oncotarget. 18065.; Cancer Genome Atlas Research N. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014; 513: 202–209.; Müller P., Rothschild S. I., Arnold W. et al. Metastatic spread in patients with non-small cell lung cancer is associated with a reduced density of tumor-infiltrating T cells. Cancer Immunol Immunother 2016; 65: 1–1.; Kollmann D., Ignatova D., Jedamzik J. et al. Expression of programmed cell death protein 1 by tumor-infiltrating lymphocytes and tumor cells is associated with advanced tumor stage in patients with esophageal adenocarcinoma. Ann Surg Oncol 2017; 24: 2698–706.; Huszno J., Nożyńska E. Z., Lange D. et al. The association of tumor lymphocyte infiltration with clinicopathological factors and survival in breast cancer. Pol J Pathol 2017; 68: 26–32.; Lu J., Xu Y., Wu Y. et al. Tumor-infiltrating CD8 + T cells combined with tumor-associated CD68 + macrophages predict postoperative prognosis and adjuvant chemotherapy benefit in resected gastric cancer. BMC Cancer 2019; 920 (19).; Ebihara T., Sakai N., Koyama S. Suppression by sorted CD8 + CD11b-cells from T-cell growth factor-activated peripheral blood lymphocytes on cytolytic activity against tumor in patients with gastric carcinoma. Eur J of Cancer 1991; 27 (12): 1654–7 / 19. Hou J., Yu Z., Xiang R. et al. Correlation between infiltration of FOXP3 + regulatory T cells and expression of B7-H1 in the tumor tissues of gastric cancer. Exp Molecular Pathol 2014; 96 (3): 284–91.; Yuan X. L., Chen L., Li M-X. et al. Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX - 2-dependent manner. Clin Immunol 2010; 134 (3): 277–88.; Peng L. S., Mao F. Y., Zhao Y. L. et al. Altered phenotypic and functional characteristics of CD3 + CD56 + NKT-like cells in human gastric cancer. Oncotarget 2016; 7 (34): 55222–30. DOI:10.18632 / oncotarget. 10484; Takeuchi H., Maehara Y., Tokunaga E. et al. Prognostic Significance of Natural Killer Cell Activity in Patients With Gastric Carcinoma: A Multivariate Analysis. Am J Gastroenterol 2001; 96 (2): 574–8.; https://www.malignanttumors.org/jour/article/view/823

Availability: https://www.malignanttumors.org/jour/article/view/823
https://doi.org/10.18027/2224-5057-2020-10-4-5-15

Analysis of systemic immunity and inflammation in the prognosis of gastric adenocarcinoma ; Анализ системного иммунитета и воспаления в прогнозе аденокарциномы желудка

Authors: Khakimova G.G., Zabotina T.N., Tryakin A.A., Borunova A.A., Davidova T.V., Kalinin A.E., Vakhabova Y.V., Zakharova E.N., Tabakov D.V.

Source: Advances in Molecular Oncology; Vol 7, No 1 (2020); 38-46 ; Успехи молекулярной онкологии; Vol 7, No 1 (2020); 38-46 ; 2413-3787 ; 2313-805X

Subject Terms: gastric adenocarcinoma, cellular immunity, subpopulation of lymphocytes, neutrophilic lymphocytic index, platelet lymphocytic index, аденокарцинома желудка, клеточный иммунитет, субпопуляция лимфоцитов, нейтрофильно-лимфоцитраный индекс, тромбоцитарно-лимфоцитарный индекс

File Description: application/pdf

Relation: https://umo.abvpress.ru/jour/article/view/256/200; https://umo.abvpress.ru/jour/article/view/256

Availability: https://umo.abvpress.ru/jour/article/view/256
https://doi.org/10.17650/2313-805X-2020-7-1-38-46

Analysis of systemic immunity and inflammation in the prognosis of gastric adenocarcinoma ; Анализ системного иммунитета и воспаления в прогнозе аденокарциномы желудка

Authors: G. G. Khakimova, T. N. Zabotina, A. A. Tryakin, A. A. Borunova, T. V. Davidova, A. E. Kalinin, Yu. V. Vakhabova, E. N. Zakharova, D. V. Tabakov, Г. Г. Хакимова, Т. Н. Заботина, А. А. Трякин, А. А. Борунова, Т. В. Давыдова, А. Е. Калинин, Ю. В. Вахабова, Е. Н. Захарова, Д. В. Табаков

Source: Advances in Molecular Oncology; Том 7, № 1 (2020); 38-46 ; Успехи молекулярной онкологии; Том 7, № 1 (2020); 38-46 ; 2413-3787 ; 2313-805X ; 10.17650/2313-805X-2020-7-1

Subject Terms: тромбоцитарно-лимфоцитарный индекс, cellular immunity, subpopulation of lymphocytes, neutrophilic lymphocytic index, platelet lymphocytic index, клеточный иммунитет, субпопуляция лимфоцитов, нейтрофильно-лимфоцитраный индекс

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Relation: https://umo.abvpress.ru/jour/article/view/256/200; Global Burden of Disease Cancer Collaboration, Fitzmaurice C., Allen C. et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the Global Burden of Disease Study. JAMA Oncol 2017;3(4):524–48. DOI:10.1001/jamaoncol.2016.5688.; Давыдов М.И., Аксель Е.М. Заболеваемость злокачественными новообразованиями населения России и стран СНГ в 2004 г. Вестник РОНЦ им. Н.Н. Блохина РАМН 2008; 19(2 прил.1):52–90.; Давыдов М.И., Тер Ованесов М.В. Современная стратегия хирургического лечения рака желудка. Современная онкология 2000;2(1):4–10.; Yazici O., Sendur M.A., Ozdemir N., Aksoy S. Targeted therapies in gastric cancer and future perspectives. World J Gastroenterol 2016;22(2):471–89. DOI:10.3748/wjg.v22.i2.471.; Waddell T., Verheij M., Allum W. et al. Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013;24 Suppl 6:vi57–63. DOI:10.1093/annonc/mdt344.; Okines A.F., Norman A.R., McCloud P. et al. Meta-analysis of the REAL-2 and ML17032 trials: evaluating capecitabinebased combination chemotherapy and infused 5-fluorouracil-based combination chemotherapy for the treatment of advanced oesophago-gastric cancer. Ann Oncol 2009;20(9):1529–34. DOI:10.1093/annonc/mdp047.; Бережная Н.М. Взаимодействие клеток системы иммунитета с другими компонентами микроокружения. Онкология 2009;1(2):86–93.; Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002;420(6917):860–7. DOI:10.1038/nature01322.; Takenaka Y., Oya R., Kitamiura T. et al. Platelet count and platelet-lymphocyte ratio as prognostic markers for head and neck squamous cell carcinoma: Metaanalysis. Head Neck 2018;40(12): 2714–23. DOI:10.1002/hed.25366.; Mori M., Shuto K., Kosugi C. et al. An increase in the neutrophil-tolymphocyte ratio during adjuvant chemotherapy indicates a poor prognosis in patients with stage II or III gastric cancer. BMC Cancer 2018;18(1):1261. DOI:10.1186/s12885-018-5171-2.; Galon J., Pages F., Marincola F.M. et al. Cancer classification using the immunoscore: a worldwide task force. J Transl Med 2012;10:205. DOI:10.1186/1479-5876-10-205.; Passardi A., Scarpi E., Cavanna L. et al. Inflammatory indexes as predictors of prognosis and bevacizumab efficacy in patients with metastatic colorectal cancer. Oncotarget 2016;7(22):33210–9. DOI:10.18632/oncotarget.8901.; Gunaldi M., Goksu S., Erdem D. et al. Prognostic impact of platelet/lymphocyte and neutrophil/lymphocyte ratios in patients with gastric cancer: a multicenter study. Int J Clin Exp Med 2015;8(4):5937–42.; Кутукова С.И., Беляк Н.П., Раскин Г.А. и др. Cистемное воспаление и иммунологическое микроокружение в прогнозе течения солидных опухолей. Злокачественные опухоли 2019;9(1):29–37. DOI:10.18027/2224-5057-2019-9-1-29-37.; Desbois M., Rusakiewicz S., Locher C. et al. Natural killer cells in non-hemato-poietic malignancies. Front Immunol 2012;3:395. DOI:10.3389/fimmu.2012.00395.; Liu G.O., Song-Wen H., Ke P. Prognostic significance of preoperative CD8+ central memory T cells for operable and advanced gastric cancer Int J Clin Exp Pathol 2017;10(3):3424–30.; Mantovani A., Romero P., Palucka A.K., Marincola F.M. Tumor immunity: effector response to tumor and role of the microenvironment. Lanset 2008;371(9614): 771–83. DOI:10.1016/S0140-6736(08)60241-X.; Тупицын Н.Н. Иммунофенотип рака молочной железы. В кн.: Рак молочной железы. Под ред. Н.Е. Кушлинского, С.М. Портного, К.Г. Лактионова. М.: РАМН, 2005. С. 174–197.; https://umo.abvpress.ru/jour/article/view/256

Availability: https://umo.abvpress.ru/jour/article/view/256
https://doi.org/10.17650/2313-805X-2020-7-1-38-46

The molecular-biological factors in bladder cancer prognosis ; Молекулярно-биологические факторы прогноза рака мочевого пузыря

Authors: Абдурагимова Зайдет Рагимовна, Abduragimova Zajdet Ragimovna

Contributors: Муравьев Александр Николаевич, Muravev Aleksandr Nikolaevic, Горелов Андрей Игоревич, Gorelov Andrej Igorevic

Subject Terms: рак мочевого пузыря, предиктор, прогрессия, нейтрофильно-лимфоцитарный индекс, С-реактивный белок, тромбоцитарно-лимфоцитарный индекс, bladder cancer, predictor, progression, neutrophil-to-lymphocyte ratio, C-reactive protein, platelet-to-lymphocyte ratio

Relation: 034156; http://hdl.handle.net/11701/26294

Availability: http://hdl.handle.net/11701/26294