РЕПРОДУКТИВНОЕ ЗДОРОВЬЕ МУЖЧИН В СЕМЬЯХ С НАСЛЕДСТВЕННЫМ СИНДРОМОМ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ И ЯИЧНИКОВ

Subject Terms: BRCA1/2 mutations, сперматогенез, testosterone, мутации BRCA1/2, luteinizing hormone, тестостерон, наследственно обусловленный рак яичников, лютеинизирующий гормон, hereditary ovarian cancer, spermatogenesis

Peculiarities of morphological and functional restructuring of rat testicular parenchyma against the background of aortoiliac segment occlusion (experimental study)

Authors: D.V. Koval, O.O. Levenets, R.I. Chvankina, I.V. Smachylo, A.Z. Mykolenko

Source: Morphologia; Vol. 17 No. 3 (2023); 52-55
Morphologia; Том 17 № 3 (2023); 52-55

Subject Terms: оклюзія аорто-клубового сегменту, сім'яники, сперматогенез, aortoiliac segment occlusion, testes, spermatogenesis

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Access URL: http://morphology.dma.dp.ua/article/view/325964

Morphological and functional changes in the testicles of rats with acetylsalicylic acid poisoning

Authors: D.B. Koval, O.O. Levenets, J.-M.V. Shandra, A.Z. Mykolenko

Source: Morphologia; Vol. 17 No. 3 (2023); 56-59
Morphologia; Том 17 № 3 (2023); 56-59

Subject Terms: acetylsalicylic acid poisoning, testes, hemodynamic disorders, spermatogenesis, отруєння ацетилсаліциловою кислотою, сім'яники, розлади гемодинаміки, сперматогенез

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Access URL: http://morphology.dma.dp.ua/article/view/325966

Age-dependent telomere length changes in differentiating spermatogenic cells in azoospermic patients ; Зависимые от возраста пациента изменения длины теломер на разных этапах дифференцировки сперматогенных клеток при азооспермии

Authors: Y. M. Sagurova, A. A. Pendina, T. V. Chugunova, M. I. Krapivin, E. M. Komarova, O. A. Efimova, Я. М. Сагурова, А. А. Пендина, Т. В. Чугунова, М. И. Крапивин, Е. М Комарова, О. А. Ефимова

Contributors: This research was funded by Russian Science Foundation, grant number 24-15-00402, https://rscf.ru/project/24-15-00402/., Исследование выполнено за счет гранта Российского научного фонда № 24-15-00402, https://rscf.ru/ project/24-15-00402/.

Source: Medical Genetics; Том 24, № 9 (2025); 107-110 ; Медицинская генетика; Том 24, № 9 (2025); 107-110 ; 2073-7998

Subject Terms: сперматоциты II, spermatogenesis, azoospermia, spermatogonia, spermatocytes I, spermatocytes II, сперматогенез, азооспермия, сперматогонии, сперматоциты I

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Relation: https://www.medgen-journal.ru/jour/article/view/3190/2050; Turner K.J., Vasu V., Griffin D.K. Telomere Biology and Human Phenotype. Cells. 2019;8(1):73. doi:10.3390/cells8010073; Lindsey J., McGill N.I., Lindsey L.A., et al. In vivo loss of telomeric repeats with age in humans. Mutation Research. 1991; 256:45–48. doi:10.1016/0921-8734(91)90032-7.; Takubo K., Nakamura K.I., Izumiyama N., et al. Telomere shortening with aging in human liver. The journals of gerontology. Series A, Biological sciences and medical sciences. 2000; 55:B533– B536. doi:10.1093/gerona/55.11.B533.; Kimura M., Cherkas L.F., Kato B.S., et al. Offspring’s leukocyte telomere length, paternal age, and telomere elongation in sperm. PLoS Genetics. 2008; 4(2):e37. doi:10.1371/journal.pgen.0040037.; Aston K.I., Hunt S.C., Susser E., et al. Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for maledriven evolution of telomere length in humans. Molecular human reproduction. 2012; 18(10):517–522. doi:10.1093/molehr/gas028.; Pendina A.A., Krapivin M.I., Sagurova Y.M., et al. Telomere Length in Human Spermatogenic Cells as a New Potential Predictor of Clinical Outcomes in ART Treatment with Intracytoplasmic Injection of Testicular Spermatozoa. International journal of molecular sciences. 2023; 24(13): 10427. doi:10.3390/ijms241310427; Temura K., Ogura A., Cheong C., et al. Dynamic rearrangement of telomeres during spermatogenesis in mice. Developmental biology. 2005; 281(2):196–207. doi:10.1016/j.ydbio.2005.02.025; Achi M.V., Ravindranath N., Dym M. Telomere length in male germ cells is inversely correlated with telomerase activity. Biology of Reproduction. 2000; 63(2):591-598.; Pendina A.A., Krapivin M.I., Efimova O.A., et al. Telomere Length in Metaphase Chromosomes of Human Triploid Zygotes. International journal of molecular sciences. 2021; 22(11):5579. doi:10.3390/ijms22115579; Tire B., Ozturk S. Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos. Journal of Ovarian Research. 2023; 16(1):130. https://doi.org/10.1186/s13048-023-01211-4; Antunes D.M., Kalmbach K.H., Wang F., et al. A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity, as well as increasing mean telomere length in human spermatozoa with advancing age. Journal of Assisted Reproduction and Genetics. 2015; 32:1685–1690. doi:10.1007/s10815-015-0574-3.

Availability: https://www.medgen-journal.ru/jour/article/view/3190
https://doi.org/10.25557/2073-7998.2025.09.107-110

CLINICAL AND TRANSFUSIOLOGICAL ASPECTS OF PLATELET-RICH PLASMA APPLICATION IN NON-OBSTRUCTIVE AZOOSPERMIA ; КЛИНИЧЕСКИЕ И ТРАНСФУЗИОЛОГИЧЕСКИЕ АСПЕКТЫ ПРИМЕНЕНИЯ ТРОМБОЦИТАРНО ОБОГАЩЁННОЙ ПЛАЗМЫ ПРИ НЕОБСТРУКТИВНОЙ АЗООСПЕРМИИ

Authors: Алимов , Бахромжон

Source: Eurasian Journal of Medical and Natural Sciences; Vol. 5 No. 10 Part 2 (2025): Eurasian Journal of Medical and Natural Sciences; 257-261 ; Евразийский журнал медицинских и естественных наук; Том 5 № 10 Part 2 (2025): Евразийский журнал медицинских и естественных наук; 257-261 ; Yevrosiyo tibbiyot va tabiiy fanlar jurnali; Jild 5 Nomeri 10 Part 2 (2025): Евразийский журнал медицинских и естественных наук; 257-261 ; 2181-287X

Subject Terms: Необструктивная азооспермия, тромбоцитарно обогащённая плазма, факторы роста, сперматогенез, трансфузиология, Non-obstructive azoospermia, platelet-rich plasma, growth factors, spermatogenesis, transfusiology

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Relation: https://in-academy.uz/index.php/EJMNS/article/view/65012/40891

Availability: https://in-academy.uz/index.php/EJMNS/article/view/65012

From a reproductive specialist to a pulmonologist, or a Long path to diagnosis: clinical observations ; От репродуктолога к пульмонологу, или Долгий путь к диагнозу: клинические наблюдения

Authors: V. B. Chernykh, Yu. L. Melyanovskaya, T. A. Kyian, E. E. Bragina, O. A. Solovova, E. I. Kondratyeva, В. Б. Черных, Ю. Л. Мельяновская, Т. А. Киян, Е. Е. Брагина, О. А. Соловова, Е. И. Кондратьева

Contributors: The study was carried out as part of the research project “Complex analysis of genophenotypic correlations in cystic fibrosis and primary ciliary dyskinesia” (registration number 122032300396-1), Исследование выполнено в рамках Научно-исследовательской работы «Комплексный анализ генофенотипических корреляций при муковисцидозе и первичной цилиарной дискинезии» (регистрационный номер 122032300396-1)

Source: PULMONOLOGIYA; Том 35, № 2 (2025); 269-275 ; Пульмонология; Том 35, № 2 (2025); 269-275 ; 2541-9617 ; 0869-0189

Subject Terms: полноэкзомное секвенирование, cilium, flagellum, spermatogenesis, asthenoteratozoospermia, primary ciliary dyskinesia, whole exome sequencing, ресничка, жгутик, сперматогенез, астенотератозооспермия, первичная цилиарная дискинезия

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Relation: https://journal.pulmonology.ru/pulm/article/view/4691/3772; https://journal.pulmonology.ru/pulm/article/downloadSuppFile/4691/3264; https://journal.pulmonology.ru/pulm/article/downloadSuppFile/4691/3279; https://journal.pulmonology.ru/pulm/article/downloadSuppFile/4691/3280; World Health Organization. WHO laboratory manual for the examination and processing of human semen. World Health Organization; 2010. Available at: https://andrologylab.gr/wp-content/uploads/2020/09/WHO-Manual-2010.pdf; Брагина Е.Е., Арифулин Е.А., Сенченков Е.П. Генетически обусловленные нарушения подвижности сперматозоидов человека. Онтогенез. 2016; 47 (5): 271–286. Доступно на: http://ontogenez.org/archive/2016/5/Bragina_2016_5.pdf; Кондратьева Е.И., Авдеев С.Н., Мизерницкий Ю.Л. и др. Первичная цилиарная дискинезия : обзор проекта клинических рекомендаций 2022 года. Пульмонология. 2022; 32 (4): 517–538. DOI:10.18093/0869-0189-2022-32-4-517-538.; Aprea I., Nöthe-Menchen T., Dougherty G.W. et al. Motility of efferent duct cilia aids passage of sperm cells through the male reproductive system. Mol. Hum. Reprod. 2021; 27 (3): gaab009. DOI:10.1093/molehr/gaab009.; Черных В.Б., Соловова О.А. Мужское бесплодие: взгляд генетика на актуальную проблему. Consilium Medicum. 2019; 21 (7): 19–24. DOI:10.26442/20751753.2019.7.190517.; Derichs N., Sanz J., Von Kanel T. et al. Intestinal current measurement for diagnostic classification of patients with questionable cystic fibrosis: validation and reference data. Thorax. 2010; 65 (7): 594–599. DOI:10.1136/thx.2009.125088.; Sedova A.O., Shtaut M.I., Bragina E.E. et al. Comprehensive semen examination in patients with pancreatic-sufficient and pancreatic-insufficient cystic fibrosis. Asian J. Androl. 2023; 25 (5): 591–597. DOI:10.4103/aja2022115.; Репина С.А., Красовский С.А., Сорокина Т.М. и др. Патогенный вариант 3849+10kbC>T гена CFTR как главный предиктор сохранения фертильности у мужчин с муковисцидозом. Генетика. 2019; 55 (12): 1481–1486. DOI:10.1134/S0016675819120105.; Репина С.А., Красовский С.А., Шмарина Г.В. и др. Состояние репродуктивной системы и алгоритм решения вопроса деторождения у мужчин с муковисцидозом. Альманах клинической медицины. 2019; 47 (1): 26–37. DOI:10.18786/2072-0505-2019-47-001.; Newman L., Chopra J., Dossett C. et al. The impact of primary ciliary dyskinesia on female and male fertility : a narrative review. Hum. Reprod. Update. 2023; 29 (3): 347–367. DOI:10.1093/humupd/dmad003.; https://journal.pulmonology.ru/pulm/article/view/4691

Availability: https://journal.pulmonology.ru/pulm/article/view/4691
https://doi.org/10.18093/0869-0189-2025-35-2-269-275

РОЛЬ ОКСИДА АЗОТА В НАРУШЕНИИ МЕТАБОЛИЗМА ФРУКТОЗЫ У ЛИЦ С АСТЕНОЗОСПЕРМИЕЙ: THE ROLE OF NITRIC OXIDE IN FRUCTOSE METABOLISM DISORDERS IN ASTENOSPERMIC INDIVIDUALS

Authors: Nəzərova, G.E.

Source: Azerbaijan Medical Journal. :155-158

Subject Terms: мужское бесплодие, azot oksid, сперматогенез, nitric oxide, фруктоза, оксид азота, kişi sonsuzluğu, fruktoza, spermatogenez, male infertility, spermatogenesis, 3. Good health, fructose

ГИСТОФИЗИОЛОГИЯ МУЖСКИХ ГОНАД В ПОСТНАТАЛЬНОМ ПЕРИОДЕ

Authors: Сaидов Aкмaл Aбдуллaевич

Source: SCIENTIFIC JOURNAL OF APPLIED AND MEDICAL SCIENCES; Vol. 3 No. 6 (2024): AMALIY VA TIBBIYOT FANLARI ILMIY JURNALI; 1001-1009 ; НАУЧНЫЙ ЖУРНАЛ ПРИКЛАДНЫХ И МЕДИЦИНСКИХ НАУК; Том 3 № 6 (2024): AMALIY VA TIBBIYOT FANLARI ILMIY JURNALI; 1001-1009 ; 2181-3469

Subject Terms: сперматогенез

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Relation: https://sciencebox.uz/index.php/amaltibbiyot/article/view/11380/10387; https://sciencebox.uz/index.php/amaltibbiyot/article/view/11380

Availability: https://sciencebox.uz/index.php/amaltibbiyot/article/view/11380

Морфофункціональна характеристика яєчок людини в нормі (огляд літератури) ; Morphological and functional characteristics of the human testicles in the normal state (literature review)

Authors: Макеєнко, Вікторія Ігорівна, Старченко, Іван Іванович, Прилуцький, Олексій Костянтинович, Филенко, Борис Миколайович, Ройко, Наталія Віталіївна, Makeyenko, V. I., Starchenko, I. I., Prilutskyi, O. K., Fylenko, B. M., Roiko, N. V.

Subject Terms: морфологія, яєчко, придаток яєчка, сперматогенез, сім’явиносна протока, клітини Лейдіга, morphology, testis, epididymis, spermatogenesis, vas deferens, Leydig cells

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Relation: Морфофункціональна характеристика яєчок людини в нормі (огляд літератури) / В. І. Макеєнко, І. І. Старченко, О. К. Прилуцький, Б. М. Филенко, Н. В. Ройко // Перспективи та інновації науки (Серія «Педагогіка», Серія «Психологія», Серія «Медицина»). – 2024. – № 5 (39). – С. 1316–1329.; https://repository.pdmu.edu.ua/handle/123456789/23831

Availability: https://repository.pdmu.edu.ua/handle/123456789/23831
https://doi.org/10.52058/2786-4952-2024-5(39)-1316-1329

RELATIONSHIP BETWEEN INFECTION WITH HUMAN PAPILLOMA VIRUS AND PROBLEMS WITH FERTILITY OF WOMEN AND MEN IN MARRIED COUPLES ; ВЗАЄМОЗВ'ЯЗОК МІЖ ІНФІКУВАННЯМ ВІРУСОМ ПАПІЛОМИ ЛЮДИНИ ТА ПРОБЛЕМАМИ З ФЕРТИЛЬНІСТЮ ЖІНОК ТА ЧОЛОВІКІВ У ПОДРУЖНІХ ПАРАХ

Authors: Курташ, Н. Я., Бахматюк, І. В.

Source: Achievements of Clinical and Experimental Medicine; No. 1 (2024); 120-124 ; Достижения клинической и экспериментальной медицины; № 1 (2024); 120-124 ; Здобутки клінічної і експериментальної медицини; № 1 (2024); 120-124 ; 2415-8836 ; 1811-2471 ; 10.11603/1811-2471.2024.v.i1

Subject Terms: human papilloma virus, spermatogenesis, married couples, вірус папіломи людини, сперматогенез, подружні пари

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Relation: https://ojs.tdmu.edu.ua/index.php/zdobutky-eks-med/article/view/14533/13371

Availability: https://ojs.tdmu.edu.ua/index.php/zdobutky-eks-med/article/view/14533
https://doi.org/10.11603/1811-2471.2024.v.i1.14533

Prevalence of AZFс Y chromosome microdeletions and association with spermatogenesis in Russian men from the general population ; Распространенность микроделеций AZFc региона Y-хромосомы и влияние на сперматогенез у российских мужчин из общей популяции

Authors: L. V. Osadchuk, G. V. Vasiliev, M. K. Ivanov, M. A. Prasolova, M. A. Kleshchev, A. V. Osadchuk, Л. В. Осадчук, Г. В. Васильев, М. К. Иванов, М. А. Прасолова, М. А. Клещев, А. В. Осадчук

Contributors: This study was supported by the state assignment FWNR-2022-0021.

Source: Vavilov Journal of Genetics and Breeding; Том 28, № 7 (2024); 780-791 ; Вавиловский журнал генетики и селекции; Том 28, № 7 (2024); 780-791 ; 2500-3259 ; 10.18699/vjgb-24-75

Subject Terms: общая популяция, spermatogenesis, male fertility, general population, сперматогенез, мужская фертильность

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Relation: https://vavilov.elpub.ru/jour/article/view/4351/1885; Akbarzadeh Khiavi M., Jalili A., Safary A., Gharedaghchi Z., Mirinezhad S.K., Mehdizadeh A., Rahmani S.A. Karyotypic abnormalities and molecular analysis of Y chromosome microdeletion in Iranian Azeri Turkish population infertile men. Syst. Biol. Reprod. Med. 2020;66(2):140-146. DOI 10.1080/19396368.2019.1682083; Alimardanian L., Saliminejad K., Razi S., Ahani A. Analysis of partial azoospermia factor c deletion and DAZ copy number in azoospermia and severe oligozoospermia. Andrologia. 2016;48(9):890-894. DOI 10.1111/and.12527; Arredi B., Ferlin A., Speltra E., Bedin C., Zuccarello D., Ganz F., Marchina E., Stuppia L., Krausz C., Foresta C. Y-chromosome haplogroups and susceptibility to azoospermia factor c microdeletion in an Italian population. J. Med. Genet. 2007;44(3):205-208. DOI 10.1136/jmg.2006.046433; Bahmanimehr A., Zeighami S., Namavar Jahromi B., Anvar Z., Parsanezhad M.E., Davari M., Montazeri S. Detection of Y chromosome microdeletions and hormonal profile analysis of infertile men undergoing assisted reproductive technologies. Int. J. Fertil. Steril. 2018;12(2):173-177. DOI 10.22074/ijfs.2018.5244; Balanovska E.V., Balanovsky O.P. The Russian Gene Pool on the Russian Plain. Moscow, 2007 (in Russian); Bansal S.K., Gupta G., Rajender S. Y chromosome b2/b3 deletions and male infertility: a comprehensive meta-analysis, trial sequential analysis and systematic review. Mutat. Res. Rev. Mutat. Res. 2016a; 768:78-90. DOI 10.1016/j.mrrev.2016.04.007; Bansal S.K., Jaiswal D., Gupta N., Singh K., Dada R., Sankhwar S.N., Gupta G., Rajender S. Gr/gr deletions on Y-chromosome correlate with male infertility: an original study, meta-analyses, and trial sequential analyses. Sci. Rep. 2016b;6:19798. DOI 10.1038/srep19798; Barkov I.Yu., Soroka N.E., Popova A.Yu., Gamidov S.I., Belyaeva N.A., Glinkina Zh.I., Kalinina E.A., Trofimov D.Yu., Sukhikh G.T. Diagnosis of male infertility associated with microdeletions at the AZF locus of the Y chromosome. Akusherstvo i Ginekologiya = Obstetrics and Gynecology. 2014;1:59-64 (in Russian); Behulova R., Varga I., Strhakova L., Bozikova A., Gabrikova D., Boronova I., Repiska V. Incidence of microdeletions in the AZF region of the Y chromosome in Slovak patients with azoospermia. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech. Repub. 2011;155(1): 33-38. DOI 10.5507/bp.2011.006; Beyaz C.C., Gunes S., Onem K., Kulac T., Asci R. Partial deletions of Y-chromosome in infertile men with non-obstructive azoospermia and oligoasthenoteratozoospermia in a Turkish population. In Vivo. 2017;31(3):365-371. DOI 10.21873/invivo.11068; Chernykh V.B., Chukhrova A.L., Beskorovainaya T.S., Grishina E.M., Sorokina T.M., Shileiko L.V., Gogolevsky P.A., Kalugina A.S., Morina G.V., Togobetsky A.S., Tanevsky V.E., Zdanovsky V.M., Gogolevskaya I.K., Kramerov D.A., Polyakov A.V., Kurilo L.F. Types of Y chromosome deletions and their frequency in infertile men. Russ. J. Genet. 2006;42(8):936-941. DOI 10.1134/S1022795406080138; ChernykhV.B., Rudneva S.A., Sorokina T.M., Shileyko L.V., Kurilo L.F., Ryzhkova O.P., Chukhrova A.L., Polyakov A.V. Characteristics of spermatogenesis in infertile men with the AZFc region deletions. Andrologiya i Genitalnaya Khirurgiya = Andrology and Genital Surgery. 2014;2:48-57 (in Russian); Chernykh V.B., Ryzhkova O.P., Kuznetsova I.A., Kazaryan M.S., Sorokina T.M., Kurilo L.F., Schagina O.A., Polyakov A.V. Deletions in AZFc region of Y chromosome in Russian fertile men. Russ. J. Genet. 2022;58(7):850-856. DOI 10.1134/s1022795422070043; Choi J., Song S.H., Bak C.W., Sung S.R., Yoon T.K., Lee D.R., Shim S.H. Impaired spermatogenesis and gr/gr deletions related to Y chromosome haplogroups in Korean men. PLoS One. 2012;7(8): e43550. DOI 10.1371/journal.pone.0043550; Cioppi F., Rosta V., Krausz C. Genetics of azoospermia. Int. J. Mol. 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DOI 10.17116/repro2017234109-113 (in Russian).; https://vavilov.elpub.ru/jour/article/view/4351

Availability: https://vavilov.elpub.ru/jour/article/view/4351
https://doi.org/10.18699/vjgb-24-86

The study of the influence of Thlaspi arvense L. on the characteristics of the reproductive system of male rats ; Изучение влияния ярутки полевой (Thlaspi arvense L.) на характеристики репродуктивной системы самцов крыс

Authors: R. G. Farkhutdinov, K. A. Pupykina, L. A. Sharafutdinova, A. M. Fedorova, Z. R. Hismatullina, M. I. Garipova, E. F. Koroleva, A. A. Yamaleeva, T. D. Rendyuk, Р. Г. Фархутдинов, К. А. Пупыкина, Л. А. Шарафутдинова, А. М. Федорова, З. Р. Хисматуллина, М. И. Гарипова, Е. Ф. Королева, А. А. Ямалеева, Т. Д. Рендюк

Source: Drug development & registration; Том 13, № 2 (2024); 208-216 ; Разработка и регистрация лекарственных средств; Том 13, № 2 (2024); 208-216 ; 2658-5049 ; 2305-2066

Subject Terms: тестостерон, sexual behavior, sperm motility, spermatogenesis, testosterone, половое поведение, подвижность сперматозоидов, сперматогенез

File Description: application/pdf

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Availability: https://www.pharmjournal.ru/jour/article/view/1828
https://doi.org/10.33380/2305-2066-2024-13-2-1677

Coenzyme Q10 and embryonic development: a potential role in reproductive medicine ; Коэнзим Q10 и эмбриональное развитие: потенциальная роль в репродуктивной медицине

Authors: A. U. Khamadyanova, R. M. Mannanov, D. M. Smakova, F. I. Musaeva, D. G. Bedelov, A. E. Ibragimov, A. A. Rusinova, M. M. Salikhova, S. V. Shtukaturova, T. V. Doroshenko, M. V. Fattakhova, M. K. Rakhimova, L. R. Marinova, А. У. Хамадьянова, Р. М. Маннанов, Д. М. Смакова, Ф. И. Мусаева, Д. Г. Беделов, А. Э. Ибрагимов, А. А. Русинова, М. М. Салихова, С. В. Штукатурова, Т. В. Дорошенко, М. В. Фаттахова, М. К. Рахимова, Л. Р. Маринова

Source: Obstetrics, Gynecology and Reproduction; Vol 18, No 5 (2024); 720-734 ; Акушерство, Гинекология и Репродукция; Vol 18, No 5 (2024); 720-734 ; 2500-3194 ; 2313-7347

Subject Terms: сперматогенез, coenzyme Q10, CoQ10, oxidative stress, reproduction, mitochondria, organogenesis, oogenesis, spermatogenesis, коэнзим Q10, окислительный стресс, репродукция, митохондрии, органогенез, оогенез

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Availability: https://www.gynecology.su/jour/article/view/2136
https://doi.org/10.17749/2313-7347/ob.gyn.rep.2024.541

Balanced X-autosome translocations and male infertility ; Сбалансированные Х-аутосомные транслокации и мужское бесплодие

Authors: M. V. Andreeva, L. F. Kurilo, V. B. Chernykh, М. В. Андреева, Л. Ф. Курило, В. Б. Черных

Contributors: The work was carried out under the state assignment for the Research Centre for Medical Genetics., Работа выполнена в рамках государственного задания Минобрнауки России для ФГБНУ «МГНЦ».

Source: Medical Genetics; Том 23, № 3 (2024); 3-11 ; Медицинская генетика; Том 23, № 3 (2024); 3-11 ; 2073-7998

Subject Terms: фертильность, male infertility, meiosis, germ cells, spermatogenesis, fertility, мужское бесплодие, мейоз, половые клетки, сперматогенез

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Relation: https://www.medgen-journal.ru/jour/article/view/2451/1775; Zegers-Hochschild F., Adamson G.D., de Mouzon J., et al. International Committee for Monitoring Assisted Reproductive Technology; World Health Organization. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril. 2009;92(5):1520-4. doi:10.1016/j.fertnstert.2009.09.009.; Sharlip I.D., Jarow J.P., Belker A.M., et al. Best practice policies for male infertility. Fertil Steril. 2002;77(5):873-82. doi:10.1016/s0015-0282(02)03105-9.; Thonneau P., Marchand S., Tallec A., et al. Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988-1989). Hum Reprod. 1991;6(6):811-6. doi:10.1093/oxfordjournals.humrep.a137433.; WHO laboratory manual for the examination and processing of human semen. 5th ed. WHO, 2010. 271 p.; Chandley A.C. The chromosomal basis of human infertility. Br Med Bull. 1979;35(2):181-6. doi:10.1093/oxfordjournals.bmb.a071567.; Mattei M.G., Mattei J.F., Ayme S., Giraud F. X-autosome translocations: cytogenetic characteristics and their consequences. Hum Genet. 1982;61(4):295-309. doi:10.1007/BF00276593.; McKinlay Gardner R.J., Amor D.J. Gardner and Sutherland’s Chromosome Abnormalities and Genetic Counseling, 5 edn, Oxford Monographs on Medical Genetics (New York, 2018; online edn, Oxford Academic, 1 Feb. 2018), https://doi.org/10.1093/med/9780199329007.001.0001; Madan K. Balanced structural changes involving the human X: effect on sexual phenotype. Hum Genet. 1983;63(3):216-21. doi:10.1007/BF00284652.; Diedrich U., Hansmann I. A familial X-autosome translocation with the breakpoint in the “critical region”. Hum Genet. 1985;70(3):281-3. doi:10.1007/BF00273458.; Choi L., Levy G., Donlon T., et al. Azoospermia Secondary to a Novel X-Autosomal Reciprocal Translocation: 46,Y, t(X:16) (p22.1:p11.2). Mil Med. 2020;185(9-10):e1860-e1863. doi:10.1093/milmed/usaa047.; Karaer K., Ergun M.A., Weise A., et al. The case of an infertile male with an uncommon reciprocal X-autosomal translocation: how does this affect male fertility? Genet Couns. 2010;21(4):397-404. PMID: 21290969.; Leichtman D.A., Schmickel R.D., Gelehrter T.D., et al. Familial Turner syndrome. Ann Intern Med. 1978;89(4):473-6. doi:10.7326/0003-4819-89-4-473.; Li Y., Sha Y., Wei Z., et al. A familial analysis of two brothers with azoospermia caused by maternal 46,Y, t(X;1)(q28;q21) chromosomal abnormality. Andrologia. 2021;53(1):e13867. doi:10.1111/and.13867.; Dutrillaux B., Couturier J., Rotman J., et al. Stérilité et translocation familiale t (1q-;Xq+ [Sterility and familial t (1q-;Xq+) translocation]. C R Acad Hebd Seances Acad Sci D. 1972 12;274(24):3324-7. French. PMID: 4626028.; Quack B., Speed R.M., Luciani J.M., et al. Meiotic analysis of two human reciprocal X-autosome translocations. Cytogenet Cell Genet. 1988;48(1):43-7. doi:10.1159/000132583.; Solari A.J., Rahn I.M., Ferreyra M.E., Carballo M.A. The behavior of sex chromosomes in two human X-autosome translocations: failure of extensive X-inactivation spreading. Biocell. 2001;25(2):155-66. PMID: 11590891.; Perrin A., Vialard F., Douet-Guilbert N., et al. Meiotic segregation of X-autosome translocation in two carriers and implications for assisted reproduction. Reprod Biomed Online. 2009;18(6):850-5. doi:10.1016/s1472-6483(10)60036-3.; Dong Y., Pan Y., Wang R., et al. Copy number variations in spermatogenic failure patients with chromosomal abnormalities and unexplained azoospermia. Genet Mol Res. 2015;14(4):16041-9. doi:10.4238/2015.December.7.17.; Chamayou S., Sicali M., Lombardo D., et al. The decision on the embryo to transfer after Preimplantation Genetic Diagnosis for X-autosome reciprocal translocation in male carrier. Mol Cytogenet. 2018;11:63. doi:10.1186/s13039-018-0409-x.; Kalz-Füller B., Sleegers E., Schwanitz G., Schubert R. Characterisation, phenotypic manifestations and X-inactivation pattern in 14 patients with X-autosome translocations. Clin Genet. 1999;55(5):362-6. doi:10.1034/j.1399-0004.1999.550511.x.; Cantú J.M., Díaz M., Möller M., et al. Azoospermia and duplication 3qter as distinct consequences of a familial t(X;3) (q26;q13.2). Am J Med Genet. 1985;20(4):677-84. doi:10.1002/ajmg.1320200413.; Stengel-Rutkowski S., Zankl H., Rodewald A., et al. Aspermia, associated with a presumably balanced X/autosomal translocation karyotype 46,Y,t(X;5)(q28;q11). Hum Genet. 1976 28;31(1):97-106. doi:10.1007/BF00270405.; Требка Е.Г., Богачева А.В., Гусина Н.Б. Хромосомные транслокации как причина олигозооспермии тяжелой степени и необструктивной азооспермии у мужчин. Молекулярная и прикладная генетика. 2019;26:115-125.; Lee S., Lee S.H., Chung T.G., et al. Molecular and cytogenetic characterization of two azoospermic patients with X-autosome translocation. J Assist Reprod Genet. 2003;20(9):385-9. doi:10.1023/a:1025437329427.; Zhang H.G., Wang R.X., Li L.L., et al. Male carriers of balanced reciprocal translocations in Northeast China: sperm count, reproductive performance, and genetic counseling. Genet Mol Res. 2015;14(4):18792-8. doi:10.4238/2015.; Alhalabi M., Jaber B., Al-Baroudi B., Alchamat G.A. A Rare Inherited Reciprocal Translocation Found in Two Male Infertile Siblings. JFIV Reprod Med Genet 2014; 2:1 doi:10.4172/2375-4508.1000120; Ishikawa T., Kondo Y., Yamaguchi K., et al. An unusual reciprocal X-autosome translocation in an infertile azoospermic man. Fertil Steril. 2007;88(3):705.e15-7. doi:10.1016/j.fertnstert.2006.12.067.; Buckton K.E., Jacobs P.A., Rae L.A., et al. An inherited X-autosome translocation in man. Ann Hum Genet. 1971;35(2):171-8. doi:10.1111/j.1469-1809.1956.tb01390.x.; Hwang S.H., Lee S.M., Seo E.J., et al. [A case of male infertility with a reciprocal translocation t(X;14)(p11.4;p12)]. Korean J Lab Med. 2007;27(2):139-42. Korean. doi:10.3343/kjlm.2007.27.2.139.; Fraccaro M., Maraschio P., Pasquali F., Scappaticci S. Women heterozygous for deficiency of the (p21 leads to pter) region of the X chromosome are fertile. Hum Genet. 1977;39(3):283-92. doi:10.1007/BF00295421.; Szvetko A., Martin N., Joy C., et al. Detection of chromosome x;18 breakpoints and translocation of the xq22.3;18q23 regions resulting in variable fertility phenotypes. Case Rep Genet. 2012;2012:681747. doi:10.1155/2012/681747.; Ma S., Yuen B.H., Penaherrera M., et al. ICSI and the transmission of X-autosomal translocation: a three-generation evaluation of X;20 translocation: case report. Hum Reprod. 2003;18(7):1377-82. doi:10.1093/humrep/deg247.; Ghieh F., Barbotin A.L., Prasivoravong J., et al. Azoospermia and reciprocal translocations: should whole-exome sequencing be recommended? Basic Clin Androl. 2021;31(1):27. doi:10.1186/s12610-021-00145-5.; Faed M.J., Robertson J., Lamont M.A., et al. A cytogenetic survey of men being investigated for subfertility. J Reprod Fertil. 1979;56(1):209-16. doi:10.1530/jrf.0.0560209.; Cuoco C., Gimelli G., Maraschio P., Pasquali F. X-autosomal translocations and male sterility. Clin Genet. 1980;17:61-62.; Grzesiuk J.D., Pereira C.S., Grangeiro C.H., et al. Familial chromosomal translocation X; 22 associated with infertility and recurrent X mosaicism. Mol Cytogenet. 2016 Jun 15;9:45. doi:10.1186/s13039-016-0249-5. Erratum in: Mol Cytogenet. 2016;9:53.; Marmor D., Taillemite J.L., Van den Akker J., et al. Semen analysis in subfertile balanced-translocation carriers. Fertil Steril. 1980;34(5):496-502. doi:10.1016/s0015-0282(16)45144-7.; Jalbert P., Sele B., Jalbert H. Reciprocal translocations: a way to predict the mode of imbalanced segregation by pachytene-diagram drawing. Hum Genet. 1980;55(2):209-22. doi:10.1007/BF00291769.; Alavattam K.G., Maezawa S., Andreassen P.R., Namekawa S.H. Meiotic sex chromosome inactivation and the XY body: a phase separation hypothesis. Cell Mol Life Sci. 2021;79(1):18. doi:10.1007/s00018-021-04075-3.; Oliver-Bonet M., Ko E., Martin R.H. Male infertility in reciprocal translocation carriers: the sex body affair. Cytogenet Genome Res. 2005;111(3-4):343-6. doi:10.1159/000086908.; Gabriel-Robez O., Ratomponirina C., Dutrillaux B., et al. Meiotic association between the XY chromosomes and the autosomal quadrivalent of a reciprocal translocation in two infertile men, 46,XY,t(19;22) and 46,XY,t(17;21). Cytogenet Cell Genet. 1986;43(3-4):154-60. doi:10.1159/000132314.; Perrin A., Douet-Guilbert N., Le Bris M.J., et al. Segregation of chromosomes in sperm of a t(X;18)(q11;p11.1) carrier inherited from his mother: case report. Hum Reprod. 2008;23(1):227-30. doi:10.1093/humrep/dem359.

Availability: https://www.medgen-journal.ru/jour/article/view/2451
https://doi.org/10.25557/2073-7998.2024.03.3-11

An evaluation of the Y chromosome microdeletions and spermatogenesis defects in patients with Y-autosomal translocations ; Исследование микроделеций Y-хромосомы и сперматологических нарушений у пациентов с Y-аутосомными транслокациями

Authors: M. I. Shtaut, N. V. Oparina, M. V. Andreeva, L. F. Kurilo, A. O. Solovova, T. M. Sorokina, N. V. Shilova, A. V. Polyakov, V. B. Chernykh, М. И. Штаут, Н. В. Опарина, М. В. Андреева, Л. Ф. Курило, О. А. Соловова, Т. М. Сорокина, Н. В. Шилова, А. В. Поляков, В. Б. Черных

Contributors: The study was carried out under the state assignment for the Research Centre for Medical Genetics., Работа выполнена в рамках государственного задания Минобрнауки России для ФГБНУ «МГНЦ»

Source: Medical Genetics; Том 23, № 2 (2024); 46-54 ; Медицинская генетика; Том 23, № 2 (2024); 46-54 ; 2073-7998

Subject Terms: AZF локус, microdeletions, male infertility, sex chromosomes, spermatogenesis, translocations, AZF locus, олигозооспермия, микроделеции, мужское бесплодие, половые хромосомы, сперматогенез, транслокации

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Relation: https://www.medgen-journal.ru/jour/article/view/2421/1773; Gardner and Sutherland’s Chromosome abnormalities and genetic counseling. 5th edition. R.J. McKinlay Gardner, D.J. Amor. Oxford University Press 2018.; Nielsen J., Rasmussen K. Y/autosomal translocations. Clin Genet. 1976;9(6):609-617.; Hsu L.Y. Phenotype/karyotype correlations of Y chromosome aneuploidy with emphasis on structural aberrations in postnatally diagnosed cases. Am J Med Genet. 1994;53(2):108-140.; Alitalo T., Tiihonen J., Hakola P., de la Chapelle A. Molecular characterization of a Y;15 translocation segregating in a family. Hum Genet. 1988;79(1):29-35.; Черных В.Б. Макро- и микроструктурные перестройки Y хромосомы. Медицинская генетика. 2007; 10: 45-52.; Onrat S.T., Söylemez Z., Elmas M. 46,XX,der(15),t(Y;15)(q12;p11) karyotype in an azoospermic male. Indian J Hum Genet. 2012;18(2):241-245.; Gonzales J., Lesourd S., Dutrillaux B. Mitotic and meiotic analysis of a reciprocal translocation t(Y;3) in an azoospermic male. Hum Genet. 1981;57(1):111-114.; Viguié F., Romani F., Dadoune J.P. Male infertility in a case of (Y; 6) balanced reciprocal translocation. Mitotic and meiotic study. Hum Genet. 1982;62(3):225-7.; Brisset S., Izard V., Misrahi M. et al. Cytogenetic, molecular and testicular tissue studies in an infertile 45,X male carrying an unbalanced (Y;22) translocation: case report. Hum Reprod. 2005;20(8):2168-2172.; McGowan-Jordan J., Hantings R.J., Moore S. ISCN 2020: an international system for human cytogenomic nomenclature (2020). S. Karger: Medical and Scientific Publishers; 2020.; WHO laboratory manual for the examination and processing of human semen. 5th edition. 2010; Курило Л.Ф., Дубинская В.П., Остроумова Т.В. и др. Оценка сперматогенеза по незрелым половым клеткам эякулята. Проблемы репродукции 1995;3:33-38.; Mekkawy M.K., El Guindi A.M., Mazen I.M. et al. An infertile azoospermic male with 45,X karyotype and a unique complex (Y;14);(Y;22) translocation: cytogenetic and molecular characterization. J Assist Reprod Genet. 2018;35(8):1503-1508.; Mancini A., Zollino M., Leone E. et al. A case of 45,X male: genetic reevaluation and hormonal and metabolic follow-up in adult age. Fertil Steril. 2008;90(5):2011.e17-21.; Bilen S., Okten A., Karaguzel G. et al. A 45 X male patient with 7q distal deletion and rearrangement with SRY gene translocation: a case report. Genet Couns. 2013;24(3):299-305.; Qin S., Wang X., Wang J. et al. Verification of a cryptic t(Y;15) translocation in a male with an apparent 45,X karyotype. Mol Cytogenet. 2022;15(1):3.; Maraschio P., Tupler R., Dainotti E. et al. Molecular analysis of a human Y;1 translocation in an azoospermic male. Cytogenet Cell Genet. 1994;65(4):256-260.; Buonadonna A.L., Cariola F, Caroppo E et al. Molecular and cytogenetic characterization of an azoospermic male with a de-novo Y;14 translocation and alternate centromere inactivation. Hum Reprod. 2002;17(3):564-569.; Jiang Y.T., Zhang H.G., Wang R.X. et al. Novel Y chromosome breakpoint in an infertile male with a de novo translocation t(Y;16): a case report. J Assist Reprod Genet. 2012;29(12):1427-1430.; Pinho M.J., Neves R., Costa P. et al. Unique t(Y;1)(q12;q12) reciprocal translocation with loss of the heterochromatic region of chromosome 1 in a male with azoospermia due to meiotic arrest: a case report. Hum Reprod. 2005;20(3):689-696.; Wang D., Chen R., Kong S. et al. Cytogenic and molecular studies of male infertility in cases of Y chromosome balanced reciprocal translocation. Mol Med Rep. 2017;16(2):2051-2054.; Deng S., Zhang H., Liu X. et al. Cytogenetic and molecular detection of a rare unbalanced Y;3 translocation in an infertile male: A case report. Medicine (Baltimore). 2020;99(26):e20863.; Röpke A., Stratis Y., Dossow-Scheele D. et al. Mosaicism for an unbalanced Y;21 translocation in an infertile man: a case report. J Assist Reprod Genet. 2013;30(12):1553-1558.; Giltay J.C., Kastrop P.M., Tiemessen C.H. et al. Sperm analysis in a subfertile male with a Y;16 translocation, using four-color FISH. Cytogenet Cell Genet. 1999;84(1-2):67-72.; Alves C., Carvalho F., Cremades N. et al. Unique (Y;13) translocation in a male with oligozoospermia: cytogenetic and molecular studies. Eur J Hum Genet. 2002;10(8):467-474.; Vialard F., Molina-Gomes D., Roume J. et al. Case report: Meiotic segregation in spermatozoa of a 46,X,t(Y;10)(q11.2;p15.2) fertile translocation carrier. Reprod Biomed Online. 2009;18(4):549-554.; Delobel B., Djlelati R., Gabriel-Robez O. et al. Y-autosome translocation and infertility: usefulness of molecular, cytogenetic and meiotic studies. Hum Genet. 1998;102(1):98-102.; Mennicke K., Diercks P., Schlieker H. et al. Molecular cytogenetic diagnostics in sperm. Int J Androl. 1997;20 Suppl 3:11-19.; Kékesi A., Erdei E., Török M. et al. Segregation of chromosomes in spermatozoa of four Hungarian translocation carriers. Fertil Steril. 2007;88(1):212.e5-11.

Availability: https://www.medgen-journal.ru/jour/article/view/2421
https://doi.org/10.25557/2073-7998.2024.02.46-54

Influence of surgical treatment of varicocele on the pathospermia and the level of sperm DNA fragmentation ; Влияние хирургического лечения варикоцеле на патоспермию и уровень фрагментации ДНК сперматозоидов

Authors: I. A. Panchenko, R. I. Panchenko, V. K. Naumov, И. А. Панченко, Р. И. Панченко, В. К. Наумов

Source: Andrology and Genital Surgery; Том 25, № 2 (2024); 104-109 ; Андрология и генитальная хирургия; Том 25, № 2 (2024); 104-109 ; 2412-8902 ; 2070-9781

Subject Terms: сперматопротекторы, spermatogenesis, fertility, DNA fragmentation, spermatoprotectors, сперматогенез, фертильность, фрагментация ДНК

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Relation: https://agx.abvpress.ru/jour/article/view/764/587; Neto FT, Bach PV, Najari BB, Li PS, Goldstein M. Spermatogenesis in humans and its affecting factors. Seminars in cell & developmental biology 2016;59:10-26.; Jensen CFS, Ostergren P, Dupree JM, Ohl DA, Sonksen J, Fode M. Varicocele and male infertility. Nature reviews Urology 2017;14:523-33.; Agarwal A, Hamada A, Esteves SC. Insight into oxidative stress in varicocele-associated male infertility: part 1. Nature reviews Urology 2012;9:678-90.; Cho CL, Esteves SC, Agarwal A. Novel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentation. Asian journal of andrology 2016;18:186-93.; Wang YJ, Zhang RQ, Lin YJ, Zhang RG, Zhang WL. Relationship between varicocele and sperm DNA damage and the effect of varicocele repair: a meta-analysis. Reproductive biomedicine online 2012;25:307-14.; Qiu D, Shi Q, Pan L. Efficacy of varicocelectomy for sperm DNA integrity improvement: A meta-analysis. Andrologia 2021;53:e13885.; Birowo P, Rahendra Wijaya J, Atmoko W, Rasyid N. The effects of varicocelectomy on the DNA fragmentation index and other sperm parameters: a meta-analysis. Basic Clin Androl 2020;30:15.; https://agx.abvpress.ru/jour/article/view/764

Availability: https://agx.abvpress.ru/jour/article/view/764
https://doi.org/10.62968/2070-9781-2024-25-2-104-109

COVID-19 Impact on Male Fertility: Review

Source: Репродуктивное здоровье. Восточная Европа. :701-709

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, мужское бесплодие, сперматогенез, coronavirus, коронавирус, COVID-19, reproductive health, репродуктивное здоровье, male infertility, spermatogenesis, 3. Good health

Analysis of Qualitative Disorders of Ejaculate of Infertile Men in the Framework of Preparation for the Program of Assisted Reproductive Technologies

Source: Health of Man; No. 3 (2023); 51-56
Здоровье мужчины; № 3 (2023); 51-56
Здоров'я чоловіка; № 3 (2023); 51-56

Subject Terms: assisted reproductive technologies, порушення репродуктивної функції, сперматогенез, DNA fragmentation, антиспермальні антитіла, антибіотикотерапія, фрагментація ДНК, spermatogenesis, 3. Good health, antisperm antibodies, antibiotic therapy, допоміжні репродуктивні технології, disorders of reproductive function, 616.697_021.3

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Access URL: https://health-man.com.ua/article/view/290636

Study of the effect of the xenobiotic hormone on the reproductive function of rats

Authors: Kononenko, Nadiia, Minukhin, Andrey, Chikitkina, Valentyna

Source: ScienceRise: Medical Science; № 5 (38) (2020); 57-62

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, УДК: 616.697:616.69:616.43-008.6, нонилфенол, репродуктивная система, гонады, сперматогенез, Nonylphenol, reproductive system, gonads, spermatogenesis, нонілфенол, репродуктивна система, гонади

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Access URL: http://journals.uran.ua/sr_med/article/download/212118/214140
http://journals.uran.ua/sr_med/article/view/212118
http://journals.uran.ua/sr_med/article/download/212118/214140
http://journals.uran.ua/sr_med/article/view/212118

Morphological and functional changes in the testicles of rats with acetylsalicylic acid poisoning ; Морфофункціональні зміни в яєчках щурів на тлі отруєння ацетилсаліциловою кислотою

Authors: Koval , D.B., Levenets , O.O., Shandra , J.-M.V., Mykolenko , A.Z.

Source: Morphologia; Vol. 17 No. 3 (2023); 56-59 ; Morphologia; Том 17 № 3 (2023); 56-59 ; 1997-9665

Subject Terms: acetylsalicylic acid poisoning, testes, hemodynamic disorders, spermatogenesis, отруєння ацетилсаліциловою кислотою, сім’яники, розлади гемодинаміки, сперматогенез

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Relation: http://morphology.dma.dp.ua/article/view/325966/315854; http://morphology.dma.dp.ua/article/view/325966

Availability: http://morphology.dma.dp.ua/article/view/325966