Αποτελέσματα αναζήτησης - "ноцицепция"

Συνεισφορές: Работа выполнена при поддержке гранта Российского научного фонда (№ 20-12-00175-п), Ивановский государственный химико-технологический университет

Πηγή: Neurology, Neuropsychiatry, Psychosomatics; Vol 15, No 3 (2023); 128-138 ; Неврология, нейропсихиатрия, психосоматика; Vol 15, No 3 (2023); 128-138 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2023-3

Θεματικοί όροι: Комплигам В Комплекс, nociception, analgesia, bioinformatics, Compligam B Complex. Contact, ноцицепция, аналгезия, биоинформатика

Περιγραφή αρχείου: application/pdf

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Систематический анализ экспериментальной и клинической фармакологии никотинамида и перспективы лечения атеросклероза. Экспериментальная и клиническая гастроэнтерология. 2022;(10):111-25. doi:10.31146/1682-8658-ecg-206-10-111-125; Kotaka M, Gover S, Vandeputte-Rutten L, et al. Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6phosphate dehydrogenase. Acta Crystallogr D Biol Crystallogr. 2005 May;61(Pt 5):495-504. doi:10.1107/S0907444905002350; Sun Q, Zhang BY, Zhang PA, et al. Downregulation of glucose-6-phosphate dehydrogenase contributes to diabetic neuropathic pain through upregulation of toll-like receptor 4 in rats. Mol Pain. 2019 JanDec;15:1744806919838659. doi:10.1177/1744806919838659; Громова ОА, Рудаков КВ, Торшин ИЮ. Систематический анализ эффектов холина на нервную систему на основе биохимических маршрутов. Анализ независимой литературы по молекулярной фармакологии и клиническим исследованиям. 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Biochim Biophys Acta. 2010 Sep;1802(9):728-32. doi:10.1016/j.bbadis.2010.06.002; Arelin M, Zierz S, Ceglarek U, et al. Recurrent Myalgia since Early InfancyMisleading Clinical Course in a Child with Carnitine Palmitoyltransferase-II Deficiency. Neuropediatrics. 2020 Feb;51(1):536. doi:10.1055/s-0039-1694977; Taggart RT, Smail D, Apolito C, Vladutiu GD. Novel mutations associated with carnitine palmitoyltransferase II deficiency. Hum Mutat. 1999;13(3):210-20. doi:10.1002/(SICI)10981004(1999)13:33.0.CO;2-0; Dawkins JL, Hulme DJ, Brahmbhatt SB, et al. Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I. Nat Genet. 2001 Mar;27(3):309-12. doi:10.1038/85879; Hanna MC, Turner AJ, Kirkness EF. Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor. J Biol Chem. 1997 Apr 18;272(16):1075660. doi:10.1074/jbc.272.16.10756; Chelban V, Wilson MP, Warman Chardon J, et al. PDXK mutations cause polyneuropathy responsive to pyridoxal 5'-phosphate supplementation. Ann Neurol. 2019 Aug;86(2):225-40. doi:10.1002/ana.25524; Han G, Gupta SD, Gable K, et al. Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8186-91. doi:10.1073/pnas.0811269106; Mühle C, Reichel M, Gulbins E, Kornhuber J. Sphingolipids in psychiatric disorders and pain syndromes. Handb Exp Pharmacol. 2013;(216):431-56. doi:10.1007/978-3-7091-1511-4_22; Waldrop GL, Holden HM, St Maurice M. The enzymes of biotin dependent CO2 metabolism: what structures reveal about their reaction mechanisms. Protein Sci. 2012 Nov;21(11):1597-619. doi:10.1002/pro.2156; Zempleni J, Hassan YI, Wijeratne SS. Biotin and biotinidase deficiency. Expert Rev Endocrinol Metab. 2008 Nov 1;3(6):715-24. doi:10.1586/17446651.3.6.715; Abed AR, Abed A, Banafshe HR, et al. Effect of biotin supplementation on neuropathic pain induced by chronic constriction of the sciatic nerve in the rat. Res Pharm Sci. 2021 May 12;16(3):250-9. doi:10.4103/1735-5362.314823; Oguma S, Ando I, Hirose T, et al. Biotin ameliorates muscle cramps of hemodialysis patients: a prospective trial. Tohoku J Exp Med. 2012 Jul;227(3):217-23. doi:10.1620/tjem.227.217; Chu CH, Cheng D. Expression, purification, characterization of human 3methylcrotonyl-CoA carboxylase (MCCC). Protein Expr Purif. 2007 Jun;53(2):421-7. doi:10.1016/j.pep.2007.01.012; Boneh A, Baumgartner M, Hayman M, Peters H. Methylcrotonyl-CoA carboxylase (MCC) deficiency associated with severe muscle pain and physical disability in an adult. J Inherit Metab Dis. 2005;28(6):1139-40. doi:10.1007/s10545-005-0163-1; Лиманова ОА, Громова ОА, Торшин ИЮ и др. Систематический анализ молекулярно-физиологических эффектов миоинозитола: данные молекулярной биологии, экспериментальной и клинической медицины. Эффективная фармакотерапия. Акушерство и гинекология. 2013;28 (3):32-41.; Калачева АГ, Торшин ИЮ, Стельмашук ЕВ и др. Нейропротекторное действие миоинозитола на клеточной модели глутаматного стресса как основа для профилактики нарушений внутриутробного развития головного мозга. Фармакокинетика и фармакодинамика. 2018;(3):9-20. doi:10.24411/2587-7836-2018-10018; Larner J. D-chiro-inositol – its functional role in insulin action and its deficit in insulin resistance. Int J Exp Diabetes Res. 2002;3(1):47-60. doi:10.1080/15604280212528; Rapiejko PJ, Northup JK, Evans T, et al. G-proteins of fat-cells. Role in hormonal regulation of intracellular inositol 1,4,5-trisphosphate. Biochem J. 1986 Nov 15;240(1):35-40. doi:10.1042/bj2400035; Ivison SM, Graham NR, Bernales CQ, et al. Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin. J Immunol. 2007 May 1;178(9):5735-43. doi:10.4049/jimmunol.178.9.5735; Zhu H, Yang Y, Zhang H, et al. Interaction between protein kinase D1 and transient receptor potential V1 in primary sensory neurons is involved in heat hypersensitivity. Pain. 2008 Jul 31;137(3):574-88. doi:10.1016/j.pain.2007.10.025; Xu JT, Tu HY, Xin WJ, et al. Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats. Exp Neurol. 2007 Aug;206(2):269-79. doi:10.1016/j.expneurol.2007.05.029; Jin J, Daniel JL, Kunapuli SP. Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets. J Biol Chem. 1998 Jan 23;273(4):2030-4. doi:10.1074/jbc.273.4.2030; Zou Y, Yang R, Li L, et al. Purinergic signaling: a potential therapeutic target for depression and chronic pain. Purinergic Signal. 2023 Mar;19(1):163-72. doi:10.1007/s11302-02109801-x; Jimenez E, Zafra F, Perez-Sen R, et al. P2Y purinergic regulation of the glycine neurotransmitter transporters. J Biol Chem. 2011 Mar 25;286(12):10712-24. doi:10.1074/jbc.M110.167056; Torres R, Croll SD, Vercollone J, et al. Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses. Pain. 2007 Aug;130(3):267-78. doi:10.1016/j.pain.2007.01.036; Greenberg JA, Bell SJ, Guan Y, Yu YH. Folic Acid supplementation and pregnancy: more than just neural tube defect prevention. Rev Obstet Gynecol. 2011 Summer;4(2):52-9.; Jiang W, Tan XY, Li JM, et al. DNA Methylation: A Target in Neuropathic Pain. Front Med (Lausanne). 2022 Jul 7;9:879902. doi:10.3389/fmed.2022.879902. eCollection 2022.; Zhang R, Huang M, Cao Z, et al. MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway. Mol Pain. 2015 Apr 12;11:19. doi:10.1186/s12990-015-0015-4; Wolthers KR, Lou X, Toogood HS, et al. Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry. Biochemistry. 2007 Oct 23;46(42):11833-44. doi:10.1021/bi701209p. Epub 2007 Sep 25.; Menon S, Lea RA, Roy B, et al. Genotypes of the MTHFR C677T and MTRR A66G genes act independently to reduce migraine disability in response to vitamin supplementation. Pharmacogenet Genomics. 2012 Oct;22(10):7419. doi:10.1097/FPC.0b013e3283576b6b; Brown GM. The biosynthesis of folic acid. II. Inhibition by sulfonamides. J Biol Chem. 1962 Feb;237:536-40.; Maki T, Takeda K. Benzoic Acid and Derivatives. In: Ullmann’s Encyclopedia of Industrial Chemistry. Wiley-VCH. doi:10.1002/14356007.a03_555. ISBN 3527306730; Takahashi N, Kuwaki T, Kiyonaka S, et al. TRPA1 underlies a sensing mechanism for O2. Nat Chem Biol. 2011 Aug 28;7(10):70111. doi:10.1038/nchembio.640; Kremeyer B, Lopera F, Cox JJ, et al. A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome. Neuron. 2010 Jun 10;66(5):671-80. doi:10.1016/j.neuron.2010.04.030; Bang S, Yang TJ, Yoo S, et al. Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben. Neurosci Lett. 2012 Jan 11;506(2):297-302. doi:10.1016/j.neulet.2011.11.026; Itoh Y, Hatano N, Hayashi H, et al. An environmental sensor, TRPV4 is a novel regulator of intracellular Ca2+ in human synoviocytes. Am J Physiol Cell Physiol. 2009 Nov;297(5):C1082-90. doi:10.1152/ajpcell.00204.2009; Köttgen M, Buchholz B, Garcia-Gonzalez MA, et al. TRPP2 and TRPV4 form a polymodal sensory channel complex. J Cell Biol. 2008 Aug 11;182(3):437-47. doi:10.1083/jcb.200805124; Boehmerle W, Huehnchen P, Lee SLL, et al. TRPV4 inhibition prevents paclitaxel-induced neurotoxicity in preclinical models. Exp Neurol. 2018 Aug;306:64-75. doi:10.1016/j.expneurol.2018.04.014; Günes HN, Bekircan-Kurt CE, Tan E, Erdem-Özdamar S. The histopathological evaluation of small fiber neuropathy in patients with vitamin B12 deficiency. Acta Neurol Belg. 2018 Sep;118(3):405-10. doi:10.1007/s13760017-0847-y; Wu F, Xu K, Liu L, et al. Vitamin B(12) Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury. Front Pharmacol. 2019 Apr 24;10:406. doi:10.3389/fphar.2019.00406; Xu J, Wang W, Zhong XX, et al. EXPRESS: Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats: Effect on loss of peripheral nerve fibers and imbalance of cytokines in the spinal dorsal horn. Mol Pain. 2016 Jun 15;12:1744806916657089. doi:10.1177/1744806916657089; Громова ОА, Торшин ИЮ, Путилина МВ и др. О механизмах синергидного действия толперизона, мелоксикама и витаминов группы В в терапии периферических болевых синдромов. Медицинский совет. 2020;(8):5464. doi:10.21518/2079-701X-2020-8-54-64; Gharibpoor F, Ghavidel-Parsa B, Sattari N, et al. Effect of vitamin B12 on the symptom severity and psychological profile of fibromyalgia patients; a prospective pre-post study. BMC Rheumatol. 2022 Sep 1;6(1):51. doi:10.1186/s41927-022-00282-y; Karedath J, Batool S, Arshad A, et al. The Impact of Vitamin B12 Supplementation on Clinical Outcomes in Patients With Diabetic Neuropathy: A Meta-Analysis of Randomized Controlled Trials. Cureus. 2022 Nov 22;14(11):e31783. doi:10.7759/cureus.31783; Didangelos T, Karlafti E, Kotzakioulafi E, et al. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, DoubleBlind, Placebo-Controlled Trial. Nutrients. 2021;13(2):395. doi:10.3390/nu13020395; Zhang A, Ackley BD, Yan D. Vitamin B12 Regulates Glial Migration and Synapse Formation through Isoform-Specific Control of PTP-3/LAR PRTP Expression. Cell Rep. 2020 Mar 24;30(12):3981-8.e3. doi:10.1016/j.celrep.2020.02

Διαθεσιμότητα: https://nnp.ima-press.net/nnp/article/view/2041
https://doi.org/10.14412/2074-2711-2023-3-128-138

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5

Academic Journal

Analgesic action of hexaazaisowurtzitane derivative in somatic pain models caused by TRPA1 and TRPV1 Ion channels activation

Συγγραφείς: S. G. Krylova, K. A. Lopatina, E. P. Zueva, E. A. Safonova, T. N. Povet’eva, Yu. V. Nesterova, O. G. Afanas’eva, P. V. Kul’pin, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

Πηγή: Бюллетень сибирской медицины, Vol 19, Iss 4, Pp 110-118 (2021)

Θεματικοί όροι: гексаазаизовюрцитан, тиовюрцин, анальгетическая активность, соматогенная ноцицепция, trp-ионные каналы, кеторолак, диклофенак, капсаицин, формалиновый тест, противовоспалительная активность, Medicine

Relation: https://bulletin.ssmu.ru/jour/article/view/4158; https://doaj.org/toc/1682-0363; https://doaj.org/toc/1819-3684; https://doaj.org/article/80f5ad2763cf450ca9a0a959b0b2685d

Διαθεσιμότητα: https://doi.org/10.20538/1682-0363-2020-4-110-118
https://doaj.org/article/80f5ad2763cf450ca9a0a959b0b2685d

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6

Academic Journal

Molecular screening for potential selective antagonists of TRPA1 ion channel

Συγγραφείς: E. A. Beskhmelnitsyna, D. V. Kravchenko, M. V. Pokrovsky, M. V. Korokin, A. A. Peresypkina, E. I. Varavin, D. A. Kostina

Πηγή: Регуляторные исследования и экспертиза лекарственных средств, Vol 7, Iss 3, Pp 186-189 (2018)

Θεματικοί όροι: ионный канал trpa1, боль, ноцицепция, воспаление, высокопроизводительный молекулярный скрининг, молекулы-кандидаты в селективные антагонисты ионного канала trpa1, trpa1 ion channel, pain, nociception, inflammation, high throughput screening, candidate molecules for selective antagonists of trpa1 ion channel, Medicine (General), R5-920

Περιγραφή αρχείου: electronic resource

Relation: https://www.vedomostincesmp.ru/jour/article/view/140; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453

Σύνδεσμος πρόσβασης: https://doaj.org/article/79de8f60e895454face3ae8ac3204ba4

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7

Academic Journal

EXPERIMENTAL STUDY OF THE MEDIATOR MECHANISMS OF THE ANTINOCYCEPTIVE ACTION OF 4-[4-OXO-(4H)-QUINAZOLIN-3-YL]-BENZOIC ACID ; ЭКСПЕРИМЕНТАЛЬНОЕ ИССЛЕДОВАНИЕ МЕДИАТОРНЫХ МЕХАНИЗМОВ АНТИНОЦИЦЕПТИВНОГО ДЕЙСТВИЯ 4-[4-ОКСО-(4Н)-ХИНАЗОЛИН-3-ИЛ] БЕНЗОЙНОЙ КИСЛОТЫ (СОЕДИНЕНИЯ ПК-66) ; ЕКСПЕРИМЕНТАЛЬНЕ ДОСЛІДЖЕННЯ МЕДІАТОРНИХ МЕХАНІЗМІВ АНТИНОЦИЦЕПТИВНОЇ ДІЇ 4-[4-ОКСО-(4Н)-ХІНАЗОЛІН-3-ІЛ] БЕНЗОЙНОЇ КИСЛОТИ (СПОЛУКИ ПК-66)

Συγγραφείς: Kramar, H. I., Stepaniuk, H. I., Voloshchuk, N. I., Alchuk, O. I.

Πηγή: Medical and Clinical Chemistry; No. 4 (2019); 67-73 ; Медицинская и клиническая химия; № 4 (2019); 67-73 ; Медична та клінічна хімія; № 4 (2019); 67-73 ; 2414-9934 ; 2410-681X ; 10.11603/mcch.2410-681X.2019.v.i4

Θεματικοί όροι: 4- [4-oxo (4H) -quinazolin-3-yl] benzoic acid, nociception, mediator mechanisms, bradykinin, 4-[4-оксо-(4Н)-хиназолин-3-ил] бензойной кислоты, ноцицепция, медиаторные механизмы, брадикинин, 4-[4-оксо-(4Н)-хіназолін-3-іл] бензойної кислоти, ноцицепція, медіаторні механізми, брадикінін

Περιγραφή αρχείου: application/pdf

Relation: https://ojs.tdmu.edu.ua/index.php/MCC/article/view/10841/10345; https://ojs.tdmu.edu.ua/index.php/MCC/article/view/10841

Διαθεσιμότητα: https://ojs.tdmu.edu.ua/index.php/MCC/article/view/10841
https://doi.org/10.11603/mcch.2410-681X.2019.v.i4.10841

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8

Academic Journal

Analysis of the association of the PRDM12 gene with pain sensitivity in individuals with psychoactive substance dependence ; Анализ ассоциации гена PRDM12 с болевой чувствительностью у лиц с зависимостью от психоактивных веществ

Συγγραφείς: E. G. Poltavskaya, D. N. Savochkina, Е. Г. Полтавская, Д. Н. Савочкина

Συνεισφορές: Исследование проведено при поддержке гранта РФФИ №17-36-01113-ОГН «Патофизиологические параметры ноцицепции, обусловленные генетическими особенностями, как предиктор риска формирования зависимости от психоактивных веществ у лиц подростково-юношеского возраста».

Πηγή: Neurology, Neuropsychiatry, Psychosomatics; Vol 12, No 1 (2020); 27-32 ; Неврология, нейропсихиатрия, психосоматика; Vol 12, No 1 (2020); 27-32 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2020-1

Θεματικοί όροι: ген PRDM12, nociception, PRDM12 gene, ноцицепция

Περιγραφή αρχείου: application/pdf

Relation: https://nnp.ima-press.net/nnp/article/view/1257/994; https://nnp.ima-press.net/nnp/article/view/1257/1013; Смирнов АВ. Предрасположенность к аддиктивному поведению в структуре интегральной индивидуальности. Психопедагогика в правоохранительных органах. 2010;(2):44–9.; Фурманов ИА, Сизанов АН, Хриптович ВА. Профилактика нарушений поведения в учреждениях образования: учебно-методическое пособие. Минск: РИВШ; 2011. 250 с.; Внуков ВВ, Черникова ИВ, Милютина НП и др. Молекулярные и клеточные механизмы опийной наркомании. Журнал фундаментальной медицины и биологии. 2013; (3):4–12.; Гуров ДЮ, Туманов ВП, Смирнов АВ и др. Морфологические изменения нейронов супраоптических ядер гипоталамуса крыс, предрасположенных к алкогольной зависимости. Современные проблемы науки и образования. 2019; (2):163.; Koob GF, Volkow ND. Neurocircuitry of addiction. Neuropsychopharmacology. 2010 Jan; 35(1):217-38. doi:10.1038/npp.2009.110.; Clarke TK, Krause K, Li T, Schumann G. An association of prodynorphin polymorphisms and opioid dependence in females in a Chinese population. Addict Biol. 2009 Jul;14(3):366-70. doi:10.1111/j.1369-1600.2009.00151.x. Epub 2009 Mar 5.; Koob GF. Neurocircuitry of alcohol addiction: synthesis from animal models. Handb Clin Neurol. 2014;125:33-54. doi:10.1016/B978-0-444-62619-6.00003-3.; Belin D, Everitt BJ. Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum. Neuron. 2008 Feb 7;57(3):432-41. doi:10.1016/j.neuron.2007.12.019.; Wise RA. The brain and reward. In: Liebman JM, Cooper SJ, editors. The neuropharmacological basis of reward. Oxford: Clarendon; 1989. P. 377–424.; Everitt BJ, Robbins TW. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci. 2005 Nov;8(11):1481-9.; Sesack SR, Grace AA. Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology. 2010 Jan;35(1): 27-47. doi:10.1038/npp.2009.93.; Bailey KP. The brain's rewarding system & addiction. J Psychosoc Nurs Ment Health Serv. 2004 Jun;42(6):14-8.; Лелевич ВВ, Курбат МН, Лелевич СВ. Нейромедиаторные механизмы опиатной наркомании (обзор литературы). Журнал ГрГМУ. 2006;(3):12-5.; Cohen JY, Haesler S, Vong L, et al. Neuron-type-specific signals for reward and punishment in the ventral tegmental area. Nature. 2012 Jan 18;482(7383):85-8. doi:10.1038/nature10754.; Mitsi V, Zachariou V. Modulation of pain, nociception, and analgesia by the brain reward center. Neuroscience. 2016 Dec 3;338:81-92. doi:10.1016/j.neuroscience.2016.05.017. Epub 2016 May 14.; Nevidimova TI, Batukhtina EI, Vetlugina TP, et al. Association of Cytokine Production with Hormone Level and Sensory Responses during the Formation of Psychoactive Drug Addiction in Men. Bull Exp Biol Med. 2015 Oct;159(6):768-71. doi:10.1007/s10517-015-3071-x. Epub 2015 Oct 31.; Chen YC, Auer-Grumbach M, Matsukawa S, et al. Transcriptional regulator PRDM12 is essential for human pain perception. Nat Genet. 2015 Jul;47(7):803-8. doi:10.1038/ng.3308. Epub 2015 May 25.; Hohenauer T, Moore AW. The Prdm family: expanding roles in stem cells and development. Development. 2012 Jul;139(13):2267-82. doi:10.1242/dev.070110.; Cortes D, Holt R, de Knegt VE. Hormonal aspects of the pathogenesis and treatment of cryptorchidism. Eur J Pediatr Surg. 2016 Oct; 26(5):409-417. Epub 2016 Sep 19.; Shirane K, Kurimoto K, Yabuta Y, et al. Global landscape and regulatory principles of DNA methylation reprogramming for germ cell specification by mouse pluripotent stem cells. Dev Cell. 2016 Oct 10;39(1):87-103. doi:10.1016/j.devcel.2016.08.008. Epub 2016 Sep 15.; Kobayashi T, Zhang H, Tang WWC, et al. Principles of early human development and germ cell program from conserved model systems. Nature. 2017 Jun 15;546(7658):416-420. doi:10.1038/nature22812. Epub 2017 Jun 7.; Dickinson ME, Flenniken AM, Ji X, et al. High-throuput discovery of novel developmental phenotypes. Nature. 2016 Sep 22;537(7621): 508-514. doi:10.1038/nature19356. Epub 2016 Sep 14.; Smagulova F, Brick K, Pu Y, et al. The evolutionary turnover of recombination hot spots contributes to speciation in mice. Genes Dev. 2016 Feb 1;30(3):266-80. doi:10.1101/gad.270009.115.; Kinameri E, Inoue T, Aruga J, et al. Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008; 3(12):e3859. doi:10.1371/journal.pone.0003859. Epub 2008 Dec 3.; Saitou M, Kagiwada S, Kurimoto K. Epigenetic reprogramming in mouse preimplantation development and primordial germ cells. Development. 2012 Jan;139(1):15-31. doi:10.1242/dev.050849.; Yang CM, Shinkai Y. Prdm12 is induced by retinoic acid and exhibits anti-proliferative properties through the cell cycle modulation of P19 embryonic carcinoma cells. Cell Struct Funct. 2013;38(2):197-206. Epub 2013 Jul 12.; Nagy V, Cole T, Van Campenhout C, et al. The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception. Cell Cycle. 2015; 14(12):1799-808. doi:10.1080/15384101.2015.1036209.; Meehan TF, Conte N, West DB, et al. Disease model discovery from 3328 gene knockouts by the international mouse phenotyping consortium. Nat Genet. 2017 Aug;49(8): 1231-1238. doi:10.1038/ng.3901. Epub 2017 Jun 26.; Бохан НА, Мандель АИ, Иванова СА и др. Старые и новые проблемы наркологии в контексте междисциплинарных исследований. Вопросы наркологии. 2017;(1):26–62.; Fedorenko OY, Golimbet VE, Ivanova SА, et al. Opening up new horizons for psychiatric genetics in the Russian Federation: moving toward a national consortium. Mol Psychiatry. 2019 Aug;24(8):1099-1111. doi:10.1038/s41380-019-0354-z. Epub 2019 Jan 21.; Невидимова ТИ, Бохан НА, Коконова ДН. 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Διαθεσιμότητα: https://nnp.ima-press.net/nnp/article/view/1257
https://doi.org/10.14412/2074-2711-2020-1-27-32

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9

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ПАТОФИЗИОЛОГИЧЕСКИЕ АСПЕКТЫ ПОСЛЕОПЕРАЦИОННОГО БОЛЕВОГО СИНДРОМА ПРИ ИНВАЗИВНЫХ ВМЕШАТЕЛЬСТВАХ В СОВРЕМЕННОЙ МЕДИЦИНЕ

Θεματικοί όροι: антиноцицептивная система, послеоперационный болевой синдром, surgery, ноцицепция, medicine, nociception, antinociceptive system, гиперальгезия, postoperative pain syndrome, медицина, 3. Good health, hyperalgesia

10

Academic Journal

Пуринергические механизмы боли и обезболивания

Θεματικοί όροι: neuropathic pain, нуклеотиды, ноцицепция, purine receptors, невропатическая боль, uridine, антиноцицепция, пуриновые рецепторы, уридин, nociception, nucleotides, antinociception, 3. Good health

11

Academic Journal

Molecular screening for potential selective antagonists of TRPA1 ion channel ; Молекулярный поиск перспективных молекул-кандидатов в селективные антагонисты ионного канала TRPA1

Συγγραφείς: E. A. Beskhmelnitsyna, D. V. Kravchenko, M. V. Pokrovsky, M. V. Korokin, A. A. Peresypkina, E. I. Varavin, D. A. Kostina, Е. А. Бесхмельницына, Д. В. Кравченко, М. В. Покровский, М. В. Корокин, А. А. Пересыпкина, Е. И. Варавин, Д. А. Костина

Πηγή: Regulatory Research and Medicine Evaluation; Том 7, № 3 (2017); 186-189 ; Регуляторные исследования и экспертиза лекарственных средств; Том 7, № 3 (2017); 186-189 ; 3034-3453 ; 3034-3062 ; undefined

Θεματικοί όροι: candidate molecules for selective antagonists of TRPA 1 ion channel, боль, ноцицепция, воспаление, высокопроизводительный молекулярный скрининг, молекулы-кандидаты в селективные антагонисты ионного канала TRPA 1, TRPA 1 ion channel, pain, nociception, inflammation, high throughput screening

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Relation: https://www.vedomostincesmp.ru/jour/article/view/140/139; Тактика и неотложная терапия болевого синдрома. Научно-информационный материал. М.: Ассоциация московских ВУЗов; 2010.; Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Hogestatt ED, et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 2004; 427(6971): 260-5.; Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, et al. 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA 2007; 104(33): 13519-24.; Shelukhina I, Mikhailov N, Abushik P, Nurulin L, Nikolsky EE, Giniatullin R. Cholinergic Nociceptive Mechanisms in Rat Meninges and Trigeminal Ganglia: Potential Implications for Migraine Pain. Front Neurol. 2017; (8): 163.; Bohonyi N, Pohoczky K, Szalontai B, Perkecz A, Kovacs K, Kajtar B, et al. Local upregulation of transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1 ion channels in rectosigmoid deep infiltrating endometriosis. Mol Pain 2017; (13): 1744806917705564.; Asai Y, Holt JR, Geleoc GS. A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea. J Assoc Res Otolaryngol. 2010; 11(1): 27-37.; Matta JA, Cornett PM, Miyares RL, Abe K, Sahibzada N, Ahern GP. General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. Proc Natl Acad Sci USA 2008; 105(25): 8784-9.; Бесхмельницына ЕА, Покровский МВ, Корокин МВ, Якушев ВИ, Гудырев ОС. Биологическая роль ионного канала TRPA1 при различных патологических состояниях. Научные ведомости Белгородского государственного университета. Серия: Медицина. Фармация 2012; 20(22-3): 30-5.; Nie Y, Huang C, Zhong C, Wortley MA, Luo Y, Luo W, et al. Cigarette smoke extract (CSE) induces transient receptor potential ankyrin 1 (TRPA1) expression via activation of HIF1α in A549 cells. Free Radic Biol Med. 2016; (99): 498-507.; Nakao S, Mabuchi M, Wang S, Koqure Y, Shimizu T, Noguchi K, et al. Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor. Bioorg Med Chem Lett. 2017; 27(14): 3167-72.; Pryde DC, Marron BE, West CW, Reister S, Amato G, Yoger K, et al. Discovery of a Series of Indazole TRPA1 Antagonists. ACS Med Chem Lett. 2017; 8(6): 666-71.; Kravchenko DV, Beskhmelnitsyna EA, Korokin MV, Avtina TV, Sernov LN, Tishin AN, Kostina DA. Molecular screening of prospective candidates for TRPA1 ion channel selective antagonists. Research Result: Pharmacology and Clinical Pharmacology 2016; 2(1): 63-6.; Skerratt S. Recent Progress in the Discovery and Development of TRPA1 Modulators. Prog Med Chem. 2017; (56): 81-115.; Mukhopadhyay I, Kulkarni A, Aranake S, Karnik P, Shetty M, Thorat S, et al. Transient receptor potential ankyrin 1 receptor activation in vitro and in vivo by pro-tussive agents: GRC 17536 as a promising anti-tussive therapeutic. PLoS One 2014; 9(5): e97005.; https://www.vedomostincesmp.ru/jour/article/view/140; undefined

Διαθεσιμότητα: https://www.vedomostincesmp.ru/jour/article/view/140

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12

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Экспериментальное исследование механизмов антиноцицептивного действия 4-[4-оксо-4н-хиназолин-3-ил] бензойной кислоты

Συγγραφείς: Stepaniuk, G.I., Степанюк, Г.И., Kramar, A.I., Крамар, А.И., Voloșciuk, N.I., Волощук, Н.И., Alciuk, A.I., Альчук, А.И.

Πηγή: Sănătate Publică, Economie şi Management în Medicină 78 (4) 143-143

Θεματικοί όροι: 4-[4-оксо-4Н-хиназолин-3-ил] бензойной кислоты, ноцицепция, адренергическая, дофаминергическая и ГАМК -ергическая системы

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Relation: https://ibn.idsi.md/vizualizare_articol/69238; urn:issn:17298687

Διαθεσιμότητα: https://ibn.idsi.md/vizualizare_articol/69238

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13

Academic Journal

Molecular screening for potential selective antagonists of TRPA 1 ion channel

Συγγραφείς: E. A. Beskhmelnitsyna, D. V. Kravchenko, M. V. Pokrovsky, M. V. Korokin, A. A. Peresypkina, E. I. Varavin, D. A. Kostina

Πηγή: Регуляторные исследования и экспертиза лекарственных средств, Vol 7, Iss 3, Pp 186-189 (2018)

Θεματικοί όροι: ионный канал trpa 1, боль, ноцицепция, воспаление, высокопроизводительный молекулярный скрининг, молекулы-кандидаты в селективные антагонисты ионного канала trpa 1, trpa 1 ion channel, pain, nociception, inflammation, high throughput screening, candidate molecules for selective antagonists of trpa 1 ion channel, Medicine (General), R5-920

Relation: https://www.vedomostincesmp.ru/jour/article/view/140; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453; https://doaj.org/article/79de8f60e895454face3ae8ac3204ba4

Διαθεσιμότητα: https://doaj.org/article/79de8f60e895454face3ae8ac3204ba4

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14

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CYTOKINE GENE POLYMORPHISMS AS PREDICTORS OF CHRONIC PAIN SYNDROME IN ONCOLOGY ; ГЕНЕТИЧЕСКИЙ ПОЛИМОРФИЗМ ЦИТОКИНОВ КАК ПРЕДИКТОР ФЕНОТИПИЧЕСКОЙ РЕАЛИЗАЦИИ ХРОНИЧЕСКОГО БОЛЕВОГО СИНДРОМА В ОНКОЛОГИИ

Συγγραφείς: O. P. Bobrova, N. A. Shnayder, M. M. Petrova, K. S. Zyryanov, D. A. Sychev, О. П. Боброва, Н. А. Шнайдер, М. М. Петрова, С. К. Зырянов, Д. А. Сычев

Πηγή: Siberian journal of oncology; Том 16, № 5 (2017); 87-94 ; Сибирский онкологический журнал; Том 16, № 5 (2017); 87-94 ; 2312-3168 ; 1814-4861 ; 10.21294/1814-4861-2017-16-5

Θεματικοί όροι: цитокиновые рецепторы, oncology, single nucleotide polymorphisms (SNPs), analgesic therapy, review, TNF-α, IL-1, IL-6, IL-10, pharmacogenetics, nociception, cytokine receptors, онкология, однонуклеотидный полиморфизм (ОНП), анальгетическая терапия, обзор, ФНО-α, фармакогенетика, ноцицепция

Περιγραφή αρχείου: application/pdf

Relation: https://www.siboncoj.ru/jour/article/view/617/479; Микаэлян М.Ф., Аджиенко В.Л. Концепции и проблемы лечения хронического болевого синдрома на современном этапе. Лекарствен- ный вестник. 2016; 2 (62): 28–30.; Яхно Н.Н., Кукушкина М.Л. Боль (практическое руководство для врачей). М.: Изд-во РАМН, 2011; 512.; Балашова Т.В., Андреева Н.А., Мнацаканяни Л.А., Котельнико- ва А.Г., Долгунов А.М. Современные представления о патогенезе боли. Тихоокеанский медицинский журнал. 2012; 3: 13–16.; Wang X.B., Li Y.S., Li J., Han Y., Liu Z.D. Interleukin-8 -251A/T gene polymorphism and lung cancer susceptibility: a meta-analysis. J Cell Mol Med. 2015 Jun; 19 (6): 1218–22. doi:10.1111/jcmm.12466.; Schmidt B.L., Hamamoto D.T., Simone D.A., Wilcox G.L. Mechanisms of cancer pain. J Mol Interv. 2010; 10 (3): 164–78. doi:10.1124/mi.10.3.7.; Yoneda T., Hata K., Nakanishi M., Nagae M., Nagayama T., Wakabayashi H., Nishisho T., Sakurai T., Hiraga T. Involvement of acidic microenvironment in the pathophysiology of cancer-associated bone pain. Bone. 2011; 48 (1): 100–5. doi:10.1016/j.bone.2010.07.009.; Grivennikov S.I., Greten F.R., Karin M. Immunity, inflammation, and cancer. Cell. 2010; 140(6): 88399. doi:10.1016/j.cell.2010.01.025.; Матвеева Л.В., Мосина Л.М. Роль цитокинов семейства интерлейкина-1 в желудочном канцерогенезе. Вестник РАМН. 2012; 11: 59–65.; Branford R., Droney J., Ross J.R. Opioid genetics: the key to personalized pain control? Clin Genet. 2012; 82: 301–310. doi:10.1111/j.1399- 0004.2012.01923.x.; Neeb L., Hellen P., Boehnke C., Hoffmann J., Schuh-Hofer S., Dirnagl U., Reuter U. IL-1beta stimulates COX-2 dependent PGE synthesis and CGRP release in rat trigeminal ganglia cells. PLoS One. 2011; 6 (3): e17360. doi:10.1371/journal.pone.0017360.; Hirata H., Tetsumoto S., Kijima T., Kida H., Kumagai T., Takahashi R., Otani Y., Inoue K., Kuhara H., Shimada K., Nagatomo I., Takeda Y., Goya S., Yoshizaki K., Kawase I., Tachibana I., Kishimoto T., Kumanogoh A. Favorable responses to tocilizumab in two patients with cancer – related cachexia. J Pain Symptom Manage. 2013; 46 (2): e9–e13. doi:10.1016/j.jpainsymman.2013.01.009.; Wang X.M., Lehky T.J., Brell J.M., Dorsey S.G. Discovering cytokines as targets for chemotherapy-induced painful peripheral neuropathy. Cytokine. 2012; 59 (1): 3–9. doi:10.1016/j.cyto.2012.03.027.; Guo G., Gao F. CXCR3: latest evidence for the in volvemen to chemokine signaling in bone cancer pain. Exp Neurol. 2015; 265: 1769. doi:10.1016/j.expneurol.2015.02.003.; Vendrell D., Macedo I., Alho M., Dionísio R., Costa L. Treatment of cancer pain by targeting cytokines. 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Tumor necrosis factor-alpha promoter polymorphism 308 G/A is not significantly associated with esophageal cancer risk: a meta-analysis. Oncotarget. 2016; 7 (48): 79901–13. doi:10.18632/oncotarget.13093.; Bandil K., Singhal P., Sharma U., Hussain S., Basu S., Parashari A., Singh V., Sehgal A., Shivam A., Ahuja P., Bharadwaj M., Banerjee B.D., Mehrotra R. Impacts of TNF-LTA SNPs/Haplotypes and Lifestyle Factors on Oral Carcinoma in an Indian Population. Mol Diagn Ther. 2016; 20 (5): 469–80. doi:10.1007/s40291-016-0215-2.; Zhao H., Zhang H.W., Zhang T., Gu X.M. Tumor necrosis factor alpha gene -308G>A polymorphism association with the risk of esophageal cancer in a Han Chinese population. Genet Mol Res. 2016 Oct 7; 15 (4). doi:10.4238/gmr.150458661.; Reyes-Gibby C.C., Spitz M.R., Yennurajalingam S., Swartz M., Gu J., Wu X., Bruera E., Shete S. Role of inflammation gene polymorphisms on pain severity in lung cancer patients. Cancer Epidemiol Biomarkers Prev. 2009; 18 (10): 2636–2642. doi:10.1158/1055-9965.EPI-09-0426.; Sun Q., Guo X., Wang Q., Zhao F. The association of TNF-308 (G/A) gene polymorphisms and hepatocellular carcinoma risk: a metaanalysis. Chin J Cancer Res. 2016; 28 (5): 536–542. doi:10.21147/j. issn.1000-9604.2016.05.09.; Rausch S.M., Gonzalez B.D., Clark M.M., Patten C., Felten S., Liu H., Li Y., Sloan J., Yang P. SNPs in PTGS2 and LTA predict pain and quality of life in long term lung cancer survivors. Lung Cancer. 2012; 77 (1): 217–23. doi:10.1016/j.lungcan.2012.02.017.; Wang Z., Liu Y., Yang L., Yin S., Zang R., Yang G. The polymorphism interleukin-8 -251A/T is associated with a significantly increased risk of cancers from a meta-analysis. Tumour Biol. 2014; 35 (7): 7115–23. doi:10.1007/s13277-014-1881-5.; Baune B.T., Dannlowski U., Domschke K., Janssen D.G., Jordan M.A., Ohrmann P., Bauer J., Biros E., Arolt V., Kugel H., Baxter A.G., Suslow T. The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression. Biol Psychiatry. 2010; 67 (6): 543–9. doi:10.1016/j. biopsych.2009.11.004; Reyes-Gibby C.C., Spitz M., Wu X., Merriman K., Etzel C., Bruera E., Kurzrock R., Shete S. Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A. Cancer Epidemiol Biomarkers Prev. 2007; 16 (12): 2745–2751. doi:10.1158/1055-9965.epi-07-0651.; Reyes Gibby C.C., Spitz M.R., Yennurajalingam S., Swartz M., Gu J., Wu X., Bruera E., Shete S. Role of inflammation gene polymorphisms on pain severity in lung cancer patients. Cancer Epidemiol Biomarkers Prev. 2009; 18 (10): 2636–42. doi:10.1158/1055-9965.EPI-09-0426.; Müerköster S., Wegehenkel K., Arlt A., Witt M., Sipos B., Kruse M.L., Sebens T., Klöppel G., Kalthoff H., Fölsch U.R., Schäfer H. Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res. 2004; 64: 1331–1337.; Gan W.Y., Li H.M., Zhang Y.G., Li C.M., Wang Y. Association between IL18-607C/A and -137G/C polymorphisms and susceptibility to non-small cell lung cancer in a Chinese population. Genet Mol Res. 2016; 15 (4). doi:10.4238/gmr15048822.; Zhao K., Xu J., Tian H. Correlation analysis between an IL-6 genetic polymorphism and non-small cell lung cancer prognosis. Genet Mol Res. 2016; 15 (1): 15017021. doi:10.4238/gmr.15017021.; Quesada B.J.R., Talpaz M., Rios A., Kurzrock R., Gutterman J.U. Clinical toxicity of interferons in cancer patients: a review. J Clin Oncol. 2015; 4 (20): 234–243. doi:10.1200/JCO.1986.4.2.234; Von Ah.D.M., Kang D.H., Carpenter J.S. Predictors of cancerrelated fatigue in women with breast cancer before, during, and after adjuvant therapy. 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J Clin Oncol. 2013; 31 (60): e69–e72. doi:10.1200/JCO.2012.44.2020.; https://www.siboncoj.ru/jour/article/view/617

Διαθεσιμότητα: https://www.siboncoj.ru/jour/article/view/617
https://doi.org/10.21294/1814-4861-2017-16-5-87-94

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15

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Общая характеристика боли. Механизм развития боли (обзор литературы)

Συγγραφείς: Б.Н. РАИМКУЛОВ, К.Б. РАИМКУЛОВА, Х.Б. РАИМКУЛОВА, Р.А. БАЕШОВ, Н.А. БХАТ

Θεματικοί όροι: боль, механизмы развития боли, ноцицепция, антиноцицепция, перцепция

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Διαθεσιμότητα: http://cyberleninka.ru/article/n/obschaya-harakteristika-boli-mehanizm-razvitiya-boli-obzor-literatury
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16

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Ионный канал trpa1 – перспективная терапевтическая мишень для лечения болевого синдрома

Συγγραφείς: Бесхмельницына Е.А., Корокин М.В., Автина Т.В., Мартынова О.В., Варавин И.И., Тишин А.Н.

Θεματικοί όροι: ионный канал TRP, TRPA1, боль, кеторолак, ноцицепция, анальгезия

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Διαθεσιμότητα: http://cyberleninka.ru/article/n/ionnyy-kanal-trpa1-perspektivnaya-terapevticheskaya-mishen-dlya-lecheniya-bolevogo-sindroma
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17

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РЕФЛЕКТОРНАЯ ВОЗБУДИМОСТЬ СПИНАЛЬНЫХ МОТОНЕЙРОНОВ У ПАЦИЕНТОВ С ОСТРОЙ ПАТОЛОГИЕЙ ОРГАНОВ БРЮШНОЙ ПОЛОСТИ

Συγγραφείς: Еремеев, А., Шайхутдинов, И., Шульман, А.

Θεματικοί όροι: MOTOR NEURONS,REFLEX IRRITABILITY,VISCERAL NOCICEPTION,HAND M-RESPONSES,МОТОНЕЙРОНЫ,РЕФЛЕКТОРНАЯ ВОЗБУДИМОСТЬ,ВИСЦЕРАЛЬНАЯ НОЦИЦЕПЦИЯ,НИ М-ОТВЕТЫ

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Διαθεσιμότητα: http://cyberleninka.ru/article/n/reflektornaya-vozbudimost-spinalnyh-motoneyronov-u-patsientov-s-ostroy-patologiey-organov-bryushnoy-polosti-1
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18

Academic Journal

Ионный канал TRPA1 – перспективная терапевтическая мишень для лечения болевого синдрома

Συγγραφείς: Бесхмельницына, Е. А., Корокин, М. В., Автина, Т. В., Мартынова, О. В., Варавин, И. И.

Θεματικοί όροι: медицина, фармакология, фармакокинетика, лекарственные средства, болевой синдром, лечение, ионный канал TRP, TRPA1, кеторолак, ноцицепция, анальгетики, анальгезия

Relation: http://dspace.bsu.edu.ru/handle/123456789/16777

Διαθεσιμότητα: http://dspace.bsu.edu.ru/handle/123456789/16777

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19

Academic Journal

Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy ; Современные представления о формировании механизмов болевого синдрома у пациенто в с о стеоартрозом. Рациональная фармакотерапия

Συγγραφείς: E. V. Igolkina, Е. В. Иголкина

Πηγή: Modern Rheumatology Journal; Том 8, № 3 (2014); 66-72 ; Современная ревматология; Том 8, № 3 (2014); 66-72 ; 2310-158X ; 1996-7012 ; 10.14412/1996-7012-2014-3

Θεματικοί όροι: лечение боли, osteoarthrosis, nociception, neuropathic pain, pain treatment, остеоартроз, ноцицепция, невропатическая боль

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