Εμφανίζονται 1 - 17 Αποτελέσματα από 17 για την αναζήτηση '"морфологическая гетерогенность"', χρόνος αναζήτησης: 0,58δλ Περιορισμός αποτελεσμάτων
  1. 1
  2. 2
    Academic Journal

    Πηγή: Siberian journal of oncology; Том 22, № 2 (2023); 93-102 ; Сибирский онкологический журнал; Том 22, № 2 (2023); 93-102 ; 2312-3168 ; 1814-4861

    Περιγραφή αρχείου: application/pdf

    Relation: https://www.siboncoj.ru/jour/article/view/2538/1099; McGuigan A., Kelly P., Turkington R.C., Jones C., Coleman H.G., McCain R.S. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol. 2018; 24(43): 4846–61. doi:10.3748/wjg.v24.i43.4846.; Park W., Chawla A., O’Reilly E.M. Pancreatic Cancer: A Review. JAMA. 2021; 326(9): 851–62. doi:10.1001/jama.2021.13027.; Dorman K., Heinemann V., Kobold S., von Bergwelt-Baildon M., Boeck S. Novel systemic treatment approaches for metastatic pancreatic cancer. Expert Opin Investig Drugs. 2022; 31(3): 249–62. doi:10.1080/13543784.2022.2037552.; Ren B., Cui M., Yang G., Wang H., Feng M., You L., Zhao Y. Tumor microenvironment participates in metastasis of pancreatic cancer. Mol Cancer. 2018; 17(1): 108. doi:10.1186/s12943-018-0858-1.; Schaffner F., Ray A.M., Dontenwill M. Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors. Cancers (Basel). 2013; 5(1): 27–47. doi:10.3390/cancers5010027.; Pan B., Guo J., Liao Q., Zhao Y. β1 and β3 integrins in breast, prostate and pancreatic cancer: A novel implication. Oncol Lett. 2018; 15(4): 5412–6. doi:10.3892/ol.2018.8076.; Sliker B.H., Goetz B.T., Barnes R., King H., Maurer H.C., Olive K.P., Solheim J.C. HLA-B infuences integrin beta-1 expression and pancreatic cancer cell migration. Exp Cell Res. 2020; 390(2): 111960. doi:10.1016/j.yexcr.2020.111960.; Casari I., Howard J.A., Robless E.E., Falasca M. Exosomal integrins and their infuence on pancreatic cancer progression and metastasis. Cancer Lett. 2021; 507: 124–34. doi:10.1016/j.canlet.2021.03.010.; Zeltz C., Primac I., Erusappan P., Alam J., Noel A., Gullberg D. Cancer-associated fbroblasts in desmoplastic tumors: emerging role of integrins. Semin Cancer Biol. 2020; 62: 166–81. doi:10.1016/j.semcancer.2019.08.004.; Görte J., Danen E., Cordes N. Therapy-Naive and Radioresistant 3-Dimensional Pancreatic Cancer Cell Cultures Are Efectively Radiosensitized by β1 Integrin Targeting. Int J Radiat Oncol Biol Phys. 2022; 112(2): 487–98. doi:10.1016/j.ijrobp.2021.08.035.; Torres C., Grippo P.J. Pancreatic cancer subtypes: a roadmap for precision medicine. Ann Med. 2018; 50(4): 277–87. doi:10.1080/07853890.2018.1453168.; Ракина Ю.Ю., Завьялова М.В., Крахмаль Н.В., Кошель А.П., Афанасьев С.Г., Вторушин С.В. Морфологические и экспрессионные особенности протоковой аденокарциномы поджелудочной железы. Сибирский онкологический журнал. 2017; 16(4): 26–31. doi:10.21294/1814-4861-2017-16-4-26-31.; Krakhmal N.V., Zavyalova M.V., Denisov E.V., Vtorushin S.V., Perelmuter V.M. Cancer Invasion: Patterns and Mechanisms. Acta Naturae. 2015; 7(2): 17–28. doi:10.32607/20758251-2015-7-2-17-28.; Dong S., Wang L., Guo Y.B., Ying H.F., Shen X.H., Meng Z.Q., Chen Hao, Chen Q.W., Li Z.S. Risk factors of liver metastasis from advanced pancreatic adenocarcinoma: a large multicenter cohort study. World J Surg Onc. 2017; 15(1): 120. doi:10.1186/s12957-017-1175-7.; https://www.siboncoj.ru/jour/article/view/2538

  3. 3
    Academic Journal

    Συνεισφορές: The study was carried out using the equipment of the Center for Collective Use “Medical Genomics” of the Tomsk National Research Medical Center, Работа выполнена с использованием оборудования ЦКП «Медицинская геномика» Томского НИМЦ

    Πηγή: Siberian journal of oncology; Том 22, № 1 (2023); 74-81 ; Сибирский онкологический журнал; Том 22, № 1 (2023); 74-81 ; 2312-3168 ; 1814-4861

    Περιγραφή αρχείου: application/pdf

    Relation: https://www.siboncoj.ru/jour/article/view/2433/1078; Шевченко Ю.А., Кузнецова М.С., Христин А.А., Сидоров С.В., Сенников С.В. Современная терапия рака молочной железы: от тамоксифена до Т-клеточной инженерии. Сибирский онкологический журнал. 2022; 21(5): 109–22. doi:10.21294/1814-4861-2022-21-5-109-122.; Graziani V., Rodriguez-Hernandez I., Maiques O., Sanz-Moreno V. The amoeboid state as part of the epithelial-to-mesenchymal transition programme. Trends Cell Biol. 2022; 32(3): 228–42. doi:10.1016/j.tcb.2021.10.004.; Wong S.Y., Hynes R.O. Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide? Cell Cycle. 2006; 5(8): 812–7. doi:10.4161/cc.5.8.2646.; Zavyalova M.V., Denisov E.V., Tashireva L.A., Savelieva O.E., Kaigorodova E.V., Krakhmal N.V., Perelmuter V.M. Intravasation as a Key Step in Cancer Metastasis. Biochemistry (Mosc). 2019; 84(7): 762–72. doi:10.1134/S0006297919070071.; Yang Y., Zheng H., Zhan Y., Fan S. An emerging tumor invasion mechanism about the collective cell migration. Am J Transl Res. 2019; 11(9): 5301–12.; Pearson G.W. Control of Invasion by Epithelial-to-Mesenchymal Transition Programs during Metastasis. J Clin Med. 2019; 8(5): 646. doi:10.3390/jcm8050646.; Lin Y.H., Zhen Y.Y., Chien K.Y., Lee I.C., Lin W.C., Chen M.Y., Pai L.M. LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration. Mol Biol Cell. 2017; 28(8): 1054–65. doi:10.1091/mbc.E15-04-0218.; Zavyalova M.V., Denisov E.V., Tashireva L.A., Gerashchenko T.S., Litviakov N.V., Skryabin N.A., Vtorushin S.V., Telegina N.S., Slonimskaya E.M., Cherdyntseva N.V., Perelmuter V.M. Phenotypic drift as a cause for intratumoral morphological heterogeneity of invasive ductal breast carcinoma not otherwise specified. Biores Open Access. 2013; 2(2): 148–54. doi:10.1089/biores.2012.0278.; Wittekind C. Diagnosis and staging of lymph node metastasis. Recent Results Cancer Res. 2000; 157: 20–8. doi:10.1007/978-3-64257151-0_3.; Alifanov V.V., Tashireva L.A., Zavyalova M.V., Perelmuter V.M. LIMCH1 as a New Potential Metastasis Predictor in Breast Cancer. Asian Pac J Cancer Prev. 2022; 23(11): 3947–52. doi:10.31557/APJCP.2022.23.11.3947.; https://www.siboncoj.ru/jour/article/view/2433

  4. 4
    Academic Journal

    Πηγή: Siberian journal of oncology; Том 21, № 5 (2022); 69-81 ; Сибирский онкологический журнал; Том 21, № 5 (2022); 69-81 ; 2312-3168 ; 1814-4861

    Περιγραφή αρχείου: application/pdf

    Relation: https://www.siboncoj.ru/jour/article/view/2310/1032; Wu Y., Han C., Gong L., Wang Z., Liu J., Liu X., Chen X., Chong Y., Liang N., Li S. Metastatic Patterns of Mediastinal Lymph Nodes in SmallSize Non-small Cell Lung Cancer (T1b). Front Surg. 2020; 7. doi:10.3389/fsurg.2020.580203.; Sereno M., Rodríguez-Esteban I., Gómez-Raposo C., Merino M., López-Gómez M., Zambrana F., Casado E. Lung cancer and peritoneal carcinomatosis. Oncol Lett. 2013; 6(3): 705–8. doi:10.3892/ol.2013.1468.; Meza R., Meernik C., Jeon J., Cote M.L. Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010. PLoS One. 2015; 10(3). doi:10.1371/journal.pone.0121323.; Yuan M., Liu J.Y., Zhang T., Zhang Y.D., Li H., Yu T.F. Prognostic Impact of the Findings on Thin-Section Computed Tomography in stage I lung adenocarcinoma with visceral pleural invasion. Sci Rep. 2018; 8(1): 4743. doi:10.1038/s41598-018-22853-1.; Lakha S., Gomez J.E., Flores R.M., Wisnivesky J.P. Prognostic significance of visceral pleural involvement in early-stage lung cancer. Chest. 2014; 146(6): 1619–26. doi:10.1378/chest.14-0204.; Савенкова О.В., Завьялова М.В., Бычков В.А., Чойнзонов Е.Л, Перельмутер В.М. Связь экспрессии матриксных металлопротеиназ с морфологической гетерогенностью, дифференцировкой опухоли и лимфогенным метастазированием плоскоклеточной карциномы гортани. Сибирский онкологический журнал. 2015; 1(1): 51–8.; An N., Leng X., Wang X., Sun Y., Chen Z. Survival comparison of Three histological subtypes of lung squamous cell carcinoma: A populationbased propensity score matching analysis. Lung Cancer. 2020; 142: 13–9. doi:10.1016/j.lungcan.2020.01.020.; Pankova O.V., Denisov E.V., Ponomaryova A.A., Gerashchenko T.S., Tuzikov S.A., Perelmuter V.M. Recurrence of squamous cell lung carcinoma is associated with the co-presence of reactive lesions in tumor-adjacent bronchial epithelium. Tumour Biol. 2016; 37(3): 3599–607. doi:10.1007/s13277-015-4196-2.; Pankova O.V., Rodionov E.O., Miller S.V., Tuzikov S.A., Tashireva L.A., Gerashchenko T.S., Denisov E.V., Perelmuter V.M. Neoadjuvant chemotherapy combined with intraoperative radiotherapy is effective to prevent recurrence in high-risk non-small cell lung cancer (NSCLC) patients. Transl Lung Cancer Res. 2020; 9(4): 988–99. doi:10.21037/tlcr-19-719.; Amin M.B., Greene F.L., Edge S.B., Compton C.C., Gershenwald J.E., Brookland R.K., Meyer L., Gress D.M., Byrd D.R., Winchester D.P. The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging. CA Cancer J Clin. 2017; 67(2): 93–9. doi:10.3322/caac.21388.; Nicholson A.G., Tsao M.S., Beasley M.B., Borczuk A.C., Brambilla E., Cooper W.A., Dacic S., Jain D., Kerr K.M., Lantuejoul S., Noguchi M., Papotti M., Rekhtman N., Scagliotti G., van Schil P., Sholl L., Yatabe Y., Yoshida A., Travis W.D. The 2021 WHO Classification of Lung Tumors: Impact of Advances Since 2015. J Thorac Oncol. 2022; 17(3): 362–87. doi:10.1016/j.jtho.2021.11.003.; Salgado R., Denkert C., Demaria S., Sirtaine N., Klauschen F., Pruneri G., Wienert S., Van den Eynden G., Baehner F.L., Penault-Llorca F., Perez E.A., Thompson E.A., Symmans W.F., Richardson A.L., Brock J., Criscitiello C., Bailey H., Ignatiadis M., Floris G., Sparano J., Kos Z., Nielsen T., Rimm D.L., Allison K.H., Reis-Filho J.S., Loibl S., Sotiriou C., Viale G., Badve S., Adams S., Willard-Gallo K., Loi S.; International TILs Working Group 2014. The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. Ann Oncol. 2015; 26(2): 259–71. doi:10.1093/annonc/mdu450.; https://www.siboncoj.ru/jour/article/view/2310

  5. 5
    Academic Journal

    Συνεισφορές: Работа выполнена при поддержке гранта РФФИ 18-315-00437

    Πηγή: Siberian journal of oncology; Том 20, № 6 (2021); 55-68 ; Сибирский онкологический журнал; Том 20, № 6 (2021); 55-68 ; 2312-3168 ; 1814-4861 ; 10.21294/1814-4861-2021-20-6

    Περιγραφή αρχείου: application/pdf

    Relation: https://www.siboncoj.ru/jour/article/view/1985/931; Virchow R. Cellular pathology. As based upon physiological and pathological histology. Lecture XVI--Atheromatous affection of arteries. 1858. Nutr Rev. 1989 Jan; 47(1): 23–5. doi:10.1111/j.1753-4887.1989.tb02747.x.; Strauss Y., Globus J. Spongioblastoma with unusually rapid growth following decompression. Neurol. Bull. 1918; 1: 273–279.; Земская А.Г. Мультиформные глиобластомы головного мозга. Л., 1976. 178 с.; Смирнов Л.И. Морфология нервной системы, общая нормальная и патологическая гистология. М., 1935. 256 с.; Гейманович А.И., Смирнова Л.И. Опухоли центральной нервной системы. Гос. мед. издат. УССР, 1936; С. 401–421.; Васкин И.С., Васильев А.А. Патогистологическая характеристика опухолей центральной нервной системы. Современная хирургия. 1934; 6: 506–526.; Савенко С.Н. Мультиформная спонгиобластома. Опухоли центральной нервной системы. 1936; С. 424–443.; Scherer H., Gliomstudien. I.I. Uber die Grenzen der Zelldiagnostik der Gehirngeschwulsten, gargestellt am Beispiel des «Glioblastoma multiforme ganglioides. Virchow s, Arch. 1935; 294: 795–822.; Scherer H. The forms of growth in gliomas and their practical significance. Brain. 1940; 63: 11–35.; Hegi M.E., Diserens A.C., Gorlia T., Hamou M.F., de Tribolet N., Weller M., Kros J.M., Hainfellner J.A., Mason W., Mariani L., Bromberg J.E., Hau P., Mirimanoff R.O., Cairncross J.G., Janzer R.C., Stupp R. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005 Mar 10; 352(10): 997–1003. doi:10.1056/NEJMoa043331.; Chinot O.L., Barrié M., Fuentes S., Eudes N., Lancelot S., Metellus P., Muracciole X., Braguer D., Ouafik L., Martin P.M., Dufour H., Figarella-Branger D. Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide. J Clin Oncol. 2007 Apr 20; 25(12): 1470–5. doi:10.1200/JCO.2006.07.4807.; Watanabe T., Nobusawa S., Kleihues P., Ohgaki H. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol. 2009 Apr; 174(4): 1149–53. doi:10.2353/ajpath.2009.080958.; Kim Y.H., Nobusawa S., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Nakazato Y., Tanaka Y., Vital A., Mariani L., Stawski R., Watanabe T., De Girolami U., Kleihues P., Ohgaki H. Molecular classification of low-grade diffuse gliomas. Am J Pathol. 2010 Dec; 177(6): 2708–14. doi:10.2353/ajpath.2010.100680.; Labussière M., Idbaih A., Wang X.W., Marie Y., Boisselier B., Falet C., Paris S., Laffaire J., Carpentier C., Crinière E., Ducray F., El Hallani S., Mokhtari K., Hoang-Xuan K., Delattre J.Y., Sanson M. All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2. Neurology. 2010; 74(23): 1886–90. doi:10.1212/WNL.0b013e3181e1cf3a.; Kim Y.H., Nobusawa S., Mittelbronn M., Paulus W., Brokinkel B. Keyvani K., Sure U., Wrede K., Nakazato Y., Tanaka Y., Vital A., Mariani L., Stawski R., Watanabe T., De Girolami U., Kleihues P., Ohgaki H. Molecular classification of low-grade diffuse gliomas. Am J Pathol. 2010 Dec; 177(6): 2708–14. doi:10.2353/ajpath.2010.100680.; Hartmann C., Hentschel B., Tatagiba M., Schramm J., Schnell O., Seidel C., Stein R., Reifenberger G., Pietsch T., von Deimling A., Loeffler M., Weller M. Molecular markers in low-grade gliomas: predictive or prognostic? Clin Cancer Res. 2011; 17(13): 4588–99. doi:10.1158/1078-0432.CCR-10-3194.; Meyer M., Reimand J., Lan X., Head R., Zhu X., Kushida M., Bayani J., Pressey J.C., Lionel A.C., Clarke I.D., Cusimano M., Squire J.A., Scherer S.W., Bernstein M., Woodin M.A., Bader G.D., Dirks P.B. Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity. Proc Natl Acad Sci USA. 2015; 112(3): 851–6. doi:10.1073/pnas.1320611111.; Parker N.R., Hudson A.L., Khong P., Parkinson J.F., Dwight T., Ikin R.J., Zhu Y., Cheng Z.J., Vafaee F., Chen J., Wheeler H.R., Howell V.M. Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma. Sci Rep. 2016 Mar 4; 6: 22477. doi:10.1038/srep22477.; Qazi M.A., Vora P., Venugopal C., Sidhu S.S., Moffat J., Swanton C., Singh S.K. Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma. Ann Oncol. 2017 Jul 1; 28(7): 1448–56. doi:10.1093/annonc/mdx169.; Juillerat-Jeanneret L., Bernasconi C.C., Bricod C., Gros S., Trepey S., Benhattar J., Janzer R.C. Heterogeneity of human glioblastoma: glutathione-S-transferase and methylguanine-methyltransferase. Cancer Invest. 2008 Jul; 26(6): 597–609. doi:10.1080/07357900802072913.; Hamilton M.G., Roldán G., Magliocco A., McIntyre J.B., Parney I., Easaw J.C. Determination of the methylation status of MGMT in different regions within glioblastoma multiforme. J Neurooncol. 2011 Apr; 102(2): 255–60. doi:10.1007/s11060-010-0307-5.; Mitiushkina N.V., Iyevleva A.G., Poltoratskiy A.N., Ivantsov A.O., Togo A.V., Polyakov I.S., Orlov S.V., Matsko D.E., Novik V.I., Imyanitov E.N. Detection of EGFR mutations and EML4-ALK rearrangements in lung adenocarcinomas using archived cytological slides. Cancer Cytopathol. 2013 Jul; 121(7): 370–6. doi:10.1002/cncy.21281.; Журид И.С. К учению о спонгиобластомах. Сборник, посвященный 30-летию деятельности С.Н. Давиденкова. 1936; С. 193–194.; Маньковский Б.Н., Савенко С.Н. О корреляции клиники и структуры глиом. Советская психоневрология. 1937; 8: 43–49.; Ротенберг С.И. К характеристике мультиформных спонгиобластом. Труды II Всесоюзного съезда невропатологов и психиатров. T. IV. 1937; 331–355.; Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008 Oct 23; 455(7216): 1061–8. doi:10.1038/nature07385.; Johnson B.E., Mazor T., Hong C., Barnes M., Aihara K., McLean C.Y., Fouse S.D., Yamamoto S., Ueda H., Tatsuno K., Asthana S., Jalbert L.E., Nelson S.J., Bollen A.W., Gustafson W.C., Charron E., Weiss W.A., Smirnov I.V., Song J.S., Olshen A.B., Cha S., Zhao Y., Moore R.A., Mungall A.J., Jones S.J.M., Hirst M., Marra M.A., Saito N., Aburatani H., Mukasa A., Berger M.S., Chang S.M., Taylor B.S., Costello J.F. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science. 2014 Jan 10; 343(6167): 189–193. doi:10.1126/science.1239947.; Yip S., Miao J., Cahill D.P., Iafrate A.J., Aldape K., Nutt C.L., Louis D.N. MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance. Clin Cancer Res. 2009 Jul 15; 15(14): 4622–9. doi:10.1158/1078-0432.CCR-08-3012.; Little S.E., Popov S., Jury A., Bax D.A., Doey L., Al-Sarraj S., Jurgensmeier J.M., Jones C. Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity. Cancer Res. 2012 Apr 1; 72(7): 1614–20. doi:10.1158/0008-5472.CAN-11-4069.; Sottoriva A., Spiteri I., Piccirillo S.G., Touloumis A., Collins V.P., Marioni J.C., Curtis C., Watts C., Tavaré S. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc Natl Acad Sci USA. 2013 Mar 5; 110(10): 4009–14. doi:10.1073/pnas.1219747110.; Soeda A., Hara A., Kunisada T., Yoshimura S., Iwama T., Park D.M. The evidence of glioblastoma heterogeneity. Sci Rep. 2015 Jan 27; 5: 7979. doi:10.1038/srep07979.; Reinartz R., Wang S., Kebir S., Silver D.J., Wieland A., Zheng T., Küpper M., Rauschenbach L., Fimmers R., Shepherd T.M., Trageser D., Till A., Schäfer N., Glas M., Hillmer A.M., Cichon S., Smith A.A., Pietsch T., Liu Y., Reynolds B.A., Yachnis A., Pincus D.W., Simon M., Brüstle O., Steindler D.A., Scheffler B. Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma. Clin Cancer Res. 2017 Jan 15; 23(2): 562–574. doi:10.1158/1078-0432.CCR-15-2089.; Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J., Friedman H., Friedman A., Reardon D., Herndon J., Kinzler K.W., Velculescu V.E., Vogelstein B., Bigner D.D. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009 Feb 19; 360(8): 765–73. doi:10.1056/NEJMoa0808710.; Parkinson J.F., Wheeler H.R., Clarkson A., McKenzie C.A., Biggs M.T., Little N.S., Cook R.J., Messina M., Robinson B.G., McDonald K.L. Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma. J Neurooncol. 2008 Mar; 87(1): 71–8. doi:10.1007/s11060-007-9486-0.; Cao V.T., Jung T.Y., Jung S., Jin S.G., Moon K.S., Kim I.Y., Kang S.S., Park C.S., Lee K.H., Chae H.J. The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas. Neurosurgery. 2009 Nov; 65(5): 866–75; discussion 875. doi:10.1227/01.NEU.0000357325.90347.A1.; Akgül S., Patch A.M., D’Souza R.C.J., Mukhopadhyay P., Nones K., Kempe S., Kazakoff S.H., Jeffree R.L., Stringer B.W., Pearson J.V., Waddell N., Day B.W. Intratumoural Heterogeneity Underlies Distinct Therapy Responses and Treatment Resistance in Glioblastoma. Cancers (Basel). 2019; 11(2): 190. doi:10.3390/cancers11020190.; Lemée J.M., Clavreul A., Menei P. Intratumoral heterogeneity in glioblastoma: don’t forget the peritumoral brain zone. Neuro Oncol. 2015 Oct; 17(10): 1322–32. doi:10.1093/neuonc/nov119.; Parker N.R., Khong P., Parkinson J.F., Howell V.M., Wheeler H.R. Molecular heterogeneity in glioblastoma: potential clinical implications. Front Oncol. 2015 Mar 3; 5: 55. doi:10.3389/fonc.2015.00055.; Hemmati H.D., Nakano I., Lazareff J.A., Masterman-Smith M., Geschwind D.H., Bronner-Fraser M., Kornblum H.I. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA. 2003 Dec 9; 100(25): 15178–83. doi:10.1073/pnas.2036535100.; Singh S.K., Clarke I.D., Terasaki M., Bonn V.E., Hawkins C., Squire J., Dirks P.B. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003 Sep 15; 63(18): 5821–8.; Ding Y., Hubert C.G., Herman J., Corrin P., Toledo C.M., SkuttKakaria K., Vazquez J., Basom R., Zhang B., Risler J.K., Pollard S.M., Nam D.H., Delrow J.J., Zhu J., Lee J., DeLuca J., Olson J.M., Paddison P.J. Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells. Cancer Discov. 2013 Feb; 3(2): 198–211. doi:10.1158/2159-8290.CD-12-0353.; Herman J.A., Toledo C.M., Olson J.M., DeLuca J.G., Paddison P.J. Molecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancer. Clin Cancer Res. 2015 Jan 15; 21(2): 233–9. doi:10.1158/1078-0432.CCR-13-0645.; Lee E., Pain M., Wang H., Herman J.A., Toledo C.M., DeLuca J.G., Yong R.L., Paddison P., Zhu J. Sensitivity to BUB1B Inhibition Defines an Alternative Classification of Glioblastoma. Cancer Res. 2017; 77(20): 5518–5529. doi:10.1158/0008-5472.CAN-17-0736.; Berghoff A.S., Kiesel B., Widhalm G., Rajky O., Ricken G., Wöhrer A., Dieckmann K., Filipits M., Brandstetter A., Weller M., Kurscheid S., Hegi M.E., Zielinski C.C., Marosi C., Hainfellner J.A., Preusser M., Wick W. Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma. Neuro Oncol. 2015 Aug; 17(8): 1064–75. doi:10.1093/neuonc/nou307.; Yang I., Tihan T., Han S.J., Wrensch M.R., Wiencke J., Sughrue M.E., Parsa A.T. CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival. J Clin Neurosci. 2010 Nov; 17(11): 1381–5. doi:10.1016/j.jocn.2010.03.031.; Hussain S.F., Yang D., Suki D., Aldape K., Grimm E., Heimberger A.B. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro Oncol. 2006 Jul; 8(3): 261–79. doi:10.1215/15228517-2006-008.; Donson A.M., Birks D.K., Schittone S.A., KleinschmidtDeMasters B.K., Sun D.Y., Hemenway M.F., Handler M.H., Waziri A.E., Wang M., Foreman N.K. Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors. J Immunol. 2012 Aug 15; 189(4): 1920–7. doi:10.4049/jimmunol.1103373.; Li B., Severson E., Pignon J.C., Zhao H., Li T., Novak J., Jiang P., Shen H., Aster J.C., Rodig S., Signoretti S., Liu J.S., Liu X.S. Comprehensive analyses of tumor immunity: implications for cancer immunotherapy. Genome Biol. 2016 Aug 22; 17(1): 174. doi:10.1186/s13059-016-1028-7.; Huang B., Zhang H., Gu L., Ye B., Jian Z., Stary C., Xiong X. Advances in Immunotherapy for Glioblastoma Multiforme. J Immunol Res. 2017; 2017: 3597613. doi:10.1155/2017/3597613.; Daniel P.M., Filiz G., Tymms M.J., Ramsay R.G., Kaye A.H., Stylli S.S., Mantamadiotis T. Intratumor MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with CREB signaling and distinct target gene signatures. Exp Mol Pathol. 2018 Aug; 105(1): 23–31. doi:10.1016/j.yexmp.2018.05.009.; Neftel C., Laffy J., Filbin M.G., Hara T., Shore M.E., Rahme G.J., Richman A.R., Silverbush D., Shaw M.L., Hebert C.M., Dewitt J., Gritsch S., Perez E.M., Gonzalez Castro L.N., Lan X., Druck N., Rodman C., Dionne D., Kaplan A., Bertalan M.S., Small J., Pelton K., Becker S., Bonal D., Nguyen Q.D., Servis R.L., Fung J.M., Mylvaganam R., Mayr L., Gojo J., Haberler C., Geyeregger R., Czech T., Slavc I., Nahed B.V., Curry W.T., Carter B.S., Wakimoto H., Brastianos P.K., Batchelor T.T., StemmerRachamimov A., Martinez-Lage M., Frosch M.P., Stamenkovic I., Riggi N., Rheinbay E., Monje M., Rozenblatt-Rosen O., Cahill D.P., Patel A.P., Hunter T., Verma I.M., Ligon K.L., Louis D.N., Regev A., Bernstein B.E., Tirosh I., Suvà M.L. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. 2019 Aug 8; 178(4): 835–849.e21. doi:10.1016/j.cell.2019.06.024.; Wenger A., Ferreyra Vega S., Kling T., Bontell T.O., Jakola A.S., Carén H. Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification. Neuro Oncol. 2019 May 6; 21(5): 616–627. doi:10.1093/neuonc/noz011.; Pang L., Hu J., Li F., Yuan H., Yan M., Liao G., Xu L., Pang B., Ping Y., Xiao Y., Li X. Discovering Rare Genes Contributing to Cancer Stemness and Invasive Potential by GBM Single-Cell Transcriptional Analysis. Cancers (Basel). 2019 Dec 16; 11(12): 2025. doi:10.3390/cancers11122025.; Lee E., Yong R.L., Paddison P., Zhu J. Comparison of glioblastoma (GBM) molecular classification methods. Semin Cancer Biol. 2018 Dec; 53: 201–211. doi:10.1016/j.semcancer.2018.07.006.; https://www.siboncoj.ru/jour/article/view/1985

  6. 6
    Academic Journal

    Πηγή: Oncotarget
    Oncotarget. 2017. Vol. 8, № 37. P. 61163-61180

    Περιγραφή αρχείου: application/pdf

  7. 7
  8. 8
  9. 9
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17

    Συνεισφορές: Томский государственный университет Химический факультет Кафедра органической химии, Томский государственный университет Научное управление Лаборатории НУ, Томский государственный университет Институт биологии, экологии, почвоведения, сельского и лесного хозяйства (Биологический институт) Публикации студентов и аспирантов (БИ)

    Πηγή: Перспективы развития фундаментальных наук : сборник научных трудов XII Международной конференции студентов и молодых ученых, 21-24 апреля 2015 г. Томск, 2015. С. 790-792

    Περιγραφή αρχείου: application/pdf