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1Academic Journal
Authors: N. V. Trushenko, B. B. Lavginova, O. S. Belkina, S. N. Avdeev, Н. В. Трушенко, Б. Б. Лавгинова, О. С. Белкина, С. Н. Авдеев
Source: Meditsinskiy sovet = Medical Council; № 20 (2024); 10-16 ; Медицинский Совет; № 20 (2024); 10-16 ; 2658-5790 ; 2079-701X
Subject Terms: дупилумаб, combination inhaler, genetically engineered biological drugs, eosinophilic inflammation, dupilumab, комбинированные ингаляционные средства, генноинженерные биологические препараты, Т2-воспаление
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Relation: https://www.med-sovet.pro/jour/article/view/8747/7679; Fragoso E, Andre S, Boleo-Tome JP, Areias V, Munha J, Cardoso J. Understanding COPD: A vision on phenotypes, comorbidities and treatment approach. GI COPD - Interest Group on Chronic Obstructive Pulmonary Disease. Rev Port Pneumol (2006). 2016;22(2):101-111. https://doi.org/10.1016/j.rppnen.2015.12.001.; Pavord ID. Biologics and chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2018;141(6):1983-1991. https://doi.org/10.1016/j.jaci.2018.04.020.; Brightling CE. Chronic obstructive pulmonary disease phenotypes, biomarkers, and prognostic indicators. Allergy Asthma Proc. 2016;37(6):432-438. https://doi.org/10.2500/aap.2016.37.3996.; Barnes PJ. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2016;138(1):16-27. https://doi.org/10.1016/j.jaci.2016.05.011.; Brightling C, Greening N. Airway inflammation in COPD: progress to precision medicine. Eur Respir J. 2019;54(2):1900651. https://doi.org/10.1183/13993003.00651-2019.; Landis S, Suruki R, Maskell J, Bonar K, Hilton E, Compton C. Demographic and Clinical Characteristics of COPD Patients at Different Blood Eosinophil Levels in the UK Clinical Practice Research Datalink. COPD. 2018;15(2):177-184. https://doi.org/10.1080/15412555.2018.1441275.; Pascoe S, Locantore N, Dransfield MT, Barnes NC, Pavord ID. Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials. Lancet Respir Med. 2015;3(6):435-442. https://doi.org/10.1016/S2213-2600(15)00106-X.; Singh D, Kolsum U, Brightling CE, Locantore N, Agusti A, Tal-Singer R. Eosinophilic inflammation in COPD: prevalence and clinical characteristics. Eur Respir J. 2014;44(6):1697-1700. https://doi.org/10.1183/09031936.00162414.; George L, Brightling CE. Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease. Ther Adv Chronic Dis. 2016;7(1):34-51. https://doi.org/10.1177/2040622315609251.; Авдеев СН, Трушенко НВ, Мержоева ЗМ, Иванова МС, Кусраева ЭВ. Эозинофильное воспаление при хронической обструктивной болезни легких. Терапевтический архив. 2019;91(10):144-152. https://doi.org/10.26442/00403660.2019.10.000426.; Brusselle G, Pavord ID, Landis S, Pascoe S, Lettis S, Morjaria N et al. Blood eosinophil levels as a biomarker in COPD. Respir Med. 2018;138:21-31. https://doi.org/10.1016/j.rmed.2018.03.016.; Eltboli O, Bafadhel M, Hollins F, Wright A, Hargadon B, Kulkarni N, Brightling C. COPD exacerbation severity and frequency is associated with impaired macrophage efferocytosis of eosinophils. BMC Pulm Med. 2014;14:112. https://doi.org/10.1186/1471-2466-14-112.; Kolsum U, Damera G, Pham TH, Southworth T, Mason S, Karur P et al. Pulmonary inflammation in patients with chronic obstructive pulmonary disease with higher blood eosinophil counts. J Allergy Clin Immunol. 2017;140(4):1181-1184.e7. https://doi.org/10.1016/j.jaci.2017.04.027.; Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Bafadhel M, Christenson SA et al. Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 Inflammation. N Engl J Med. 2024;390(24):2274-2283. https://doi.org/10.1056/NEJMoa2401304.; Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med. 2004;350(26):2645-2653. https://doi.org/10.1056/NEJMoa032158.; Turato G, Semenzato U, Bazzan E, Biondini D, Tine M, Torrecilla N et al. Blood Eosinophilia Neither Reflects Tissue Eosinophils nor Worsens Clinical Outcomes in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018;197(9):1216-1219. https://doi.org/10.1164/rccm.201708-1684LE.; Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S et al. Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017;5(12):956-967. https://doi.org/10.1016/S2213-2600(17)30432-0.; Cheng SL, Lin CH. Effectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts. Int J Chron Obstruct Pulmon Dis. 2016;11:2341-2348. https://doi.org/10.2147/COPD.S115132.; Kerkhof M, Freeman D, Jones R, Chisholm A, Price DB. Predicting frequent COPD exacerbations using primary care data. Int J Chron Obstruct Pulmon Dis. 2015;10:2439-2450. https://doi.org/10.2147/COPD.S94259.; Siva R, Green RH, Brightling CE, Shelley M, Hargadon B, McKenna S et al. Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial. Eur Respir J. 2007;29(5):906-913. https://doi.org/10.1183/09031936.00146306.; Couillard S, Larivee P, Courteau J, Vanasse A. Eosinophils in COPD Exacerbations Are Associated With Increased Readmissions. Chest. 2017;151(2):366-373. https://doi.org/10.1016/j.chest.2016.10.003.; Mullerova H, Meeraus WH, Galkin DV, Albers FC, Landis SH. Clinical burden of illness among patients with severe eosinophilic COPD. Int J Chron Obstruct Pulmon Dis. 2019;14:741-755. https://doi.org/10.2147/COPD.S194511.; Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D et al. Benralizumab for the Prevention of COPD Exacerbations. N Engl J Med. 2019;381(11):1023-1034. https://doi.org/10.1056/NEJMoa1905248.; Lommatzsch M, Mohme SN, Stoll P, Virchow JC. Response to Various Biologics in Patients with Both Asthma and Chronic Obstructive Pulmonary Disease. Respiration. 2023;102(12):986-990. https://doi.org/10.1159/000534922.; Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Cole J, Bafadhel M et al. Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts. N Engl J Med. 2023;389(3):205-214. https://doi.org/10.1056/NEJMoa2303951.; Castro M, Corren J, Pavord ID, Maspero J, Wenzel S, Rabe KF et al. N Engl J Med. 2018;378(26):2486-2496. https://doi.org/10.1056/NEJMoa1804092.
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2Academic Journal
Source: Научно-практическая ревматология.
Subject Terms: АУТОИММУНИТЕТ, РЕВМАТОИДНЫЙ АРТРИТ, СИСТЕМНАЯ КРАСНАЯ ВОЛЧАНКА, МЕТОТРЕКСАТ, ГЕННОИНЖЕНЕРНЫЕ БИОЛОГИЧЕСКИЕ ПРЕПАРАТЫ, 3. Good health
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