Drug Allergy in Adults at a Multidisciplinary Hospital: Prevalence Assessment Using the Global Trigger Tool ; Лекарственно-индуцированная аллергия у взрослых в многопрофильном стационаре: оценка распространенности методом глобальных триггеров

Authors: V. R. Koval, O. I. Butranova, T. G. Konstantinova, A.Q.S. Al-Mayahi, В. Р. Коваль, О. И. Бутранова, Т. Г. Константинова, А.К.Ш. Аль-Майяхи

Source: Safety and Risk of Pharmacotherapy; Том 13, № 3 (2025); 313-323 ; Безопасность и риск фармакотерапии; Том 13, № 3 (2025); 313-323 ; 2619-1164 ; 2312-7821 ; 10.30895/2312-7821-2025-13-3

Subject Terms: моноклональные антитела, adverse drug reactions, drug allergies, H1-histamine receptor blockers, antimicrobial agents, monoclonal antibodies, нежелательные реакции, лекарственная аллергия, блокаторы H1-гистаминовых рецепторов, антибактериальные препараты

File Description: application/pdf

Relation: https://www.risksafety.ru/jour/article/view/481/1366; https://www.risksafety.ru/jour/article/view/481/1370; https://www.risksafety.ru/jour/article/view/481/1379; https://www.risksafety.ru/jour/article/view/481/1382; https://www.risksafety.ru/jour/article/view/481/1386; https://www.risksafety.ru/jour/article/view/481/1388; https://www.risksafety.ru/jour/article/view/481/1397; https://www.risksafety.ru/jour/article/view/481/1407; https://www.risksafety.ru/jour/article/view/481/1447; https://www.risksafety.ru/jour/article/view/481/1561; https://www.risksafety.ru/jour/article/downloadSuppFile/481/602; https://www.risksafety.ru/jour/article/downloadSuppFile/481/655; Doña I, Torres MJ, Celik G, Phillips E, Tanno LK, Castells M. Changing patterns in the epidemiology of drug allergy. Allergy. 2024;79(3):613–28. https://doi.org/10.1111/all.15970; Kong X, Tao X, Li L, Zhao X, Ren J, Yang S, et al. Global trends and partial forecast of adverse effects of medical treatment from 1990 to 2019: An epidemiological analysis based on the Global Burden of Disease Study 2019. BMC Public Health. 2024;24(1):295. https://doi.org/10.1186/s12889-023-17560-0; Durand M, Castelli C, Roux-Marson C, Kinowski JM, Leguelinel-Blache G. Evaluating the costs of adverse drug events in hospitalized patients: A systematic review. Health Econ Rev. 2024;14(1):11. https://doi.org/10.1186/s13561-024-00481-y; Johansson ML, Hägg S, Wallerstedt SM. Impact of information letters on the reporting rate of adverse drug reactions and the quality of the reports: A randomized controlled study. BMC Clin Pharmacol. 2011;11:14. https://doi.org/10.1186/1472-6904-11-14; Журавлева МВ, Сереброва СЮ, Кузнецова ЕВ, Каменева ТР, Власова АВ, Прокофьев АБ, Демченкова ЕЮ. Совершенствование системы фармаконадзора в медицинских организациях как возможность повышения качества фармакотерапии. Безопасность и риск фармакотерапии. 2025;13(1): 94–107. https://doi.org/10.30895/2312-7821-2025-13-1-94-107; Moraes SM, Ferrari TCA, Beleigoli A. The accuracy of the Glo­ bal Trigger Tool is higher for the identification of adverse events of greater harm: A diagnostic test study. Int J Qual Health Care. 2023;34(1):mzad005. https://doi.org/10.1093/intqhc/mzad005; Kiechle ES, McKenna CM, Carter H, Zeymo A, Gelfand BW, DeGeorge LM, et al. Medication allergy and adverse drug reaction documentation discrepancies in an urban, academic emergency department. J Med Toxicol. 2018;14(4):272–7. https://doi.org/10.1007/s13181-018-0671-7; Arnold A, Coventry LL, Foster MJ, Koplin JJ, Lucas M. The burden of self-reported antibiotic allergies in health care and how to address it: A systematic review of the evidence. J Allergy Clin Immunol Pract. 2023;11(10):3133-3145.e3. https://doi.org/10.1016/j.jaip.2023.06.025; Park CS, Yang MS, Kang DY, Park HJ, Park SY, Nam YH, et al. Drug Allergy Work Group of KAAACI. Risk factors of beta-lactam anaphylaxis in Korea: A 6-year multicenter retrospective adult case-control study. World Allergy Organ J. 2021;14(9):100580. https://doi.org/10.1016/j.waojou.2021.100580; Miller MA. Gender-based differences in the toxicity of pharmaceuticals — the Food and Drug Administration’s perspective. Int J Toxicol. 2001;20(3):149–52. https://doi.org/10.1080/109158101317097728; Thong BY, Tan TC. Epidemiology and risk factors for drug allergy. Br J Clin Pharmacol. 2011;71(5):684–700. https://doi.org/10.1111/j.1365-2125; Macy E. Addressing the epidemic of antibiotic “allergy” over-diagnosis. Ann Allergy Asthma Immunol. 2020;124(6):550–7. https://doi.org/10.1016/j.anai.2019.12.016; Скрябина АА, Терешкин НА, Никифоров ВВ, Каширин ВИ, Антипят НА, Застрожин МС, Сычев ДА. Применение метода глобальных триггеров для выявления нежелательных лекарственных реакций у пациентов стационара инфекционного профиля. Медицина. 2023;11(2):42–55. https://doi.org/10.29234/2308-9113-2023-11-2-42-55; Pandya AD, Patel K, Rana D, Gupta SD, Malhotra SD, Patel P. Global Trigger Tool: Proficient adverse drug reaction autodetection method in critical care patient units. Indian J Crit Care Med. 2020;24(3):172–8. https://doi.org/10.5005/jp-journals-10071-23367; Pallardy M, Bechara R, Whritenour J, Mitchell-Ryan S, Herzyk D, Lebrec H, et al. Drug hypersensitivity reactions: Review of the state of the science for prediction and diagnosis. Toxicol Sci. 2024;200(1):11–30. https://doi.org/10.1093/toxsci/kfae046; Rodríguez-Pérez R, de las Vecillas L, Cabañas R, Bellón T. Tools for etiologic diagnosis of drug-induced allergic conditions. Int J Mole­ cular Sciences. 2023;24(16):12577. https://doi.org/10.3390/ijms241612577; Lee EY, Copaescu AM, Trubiano JA, Phillips EJ, Wolfson AR, Ramsey A. Drug allergy in women. J Allergy Clin Immunol Pract. 2023;11(12):3615–23. https://doi.org/10.1016/j.jaip.2023.09.031; Сабанцева ЕГ, Иванова ЕВ, Рабинович ИМ. Проявления аллергических реакций, возникающих на стоматологическом приеме. Стоматология. 2021;100(6–2):29–32. https://doi.org/10.17116/stomat202110006229; de Vries ST, Denig P, Ekhart C, Burgers JS, Kleefstra N, Mol PGM, et al. Sex differences in adverse drug reactions reported to the National Pharmacovigilance Centre in the Netherlands: An explorative observational study. Br J Clin Pharmacol. 2019;85(7):1507–15. https://doi.org/10.1111/bcp.13923; Voelker DH, Gonzalez-Estrada A, Park MA. Female sex as a risk factor for penicillin drug allergy in the inpatient setting. Allergy Asthma Proc. 2022;43(2):163–7. https://doi.org/10.2500/aap.2022.43.210002; Mizukawa Y, Hama N, Miyagawa F, Takahashi H, Ogawa Y, Kurata M, et al. Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: Predictive score and outcomes. J Allergy Clin Immunol Pract. 2023;11(10):3169-3178.e7. https://doi.org/10.1016/j.jaip.2023.06.065; Li D, Gou J, Zhu J, Zhang T, Liu F, Zhang D, et al. Severe cutaneous adverse reactions to drugs: A real-world pharmacovigilance study using the FDA Adverse Event Reporting System database. Front Pharmacol. 2023;14:1117391. https://doi.org/10.3389/fphar.2023.1117391; Сычев ДА, Отделенов ВА, Краснова НМ, Ильина ЕС. Полипрагмазия: взгляд клинического фармаколога. Терапевтический архив. 2016;88(12):94–102. Sychev DA, Otdelеnov VA, Krasnova NM, Ilyina ES. Polypragmasy: A clinical pharmacologist’s view. Therapeutic Archive. 2016;88(12):94–102 (In Russ.). https://doi.org/10.17116/terarkh2016881294-102; Osanlou R, Walker L, Hughes DA, Burnside G, Pirmohamed M. Adverse drug reactions, multimorbidity and polypharmacy: A prospective analysis of 1 month of medical admissions. BMJ Open. 2022;12(7):e055551. https://doi.org/10.1136/bmjopen-2021-055551; Ferranti J, Horvath M, Cozart H, Whitehurst J, Eckstrand J, Pietrobon R, et al. A multifaceted approach to safety: The synergistic detection of adverse drug events in adult inpatients. J Patient Saf. 2008;4(3):184–190. https://doi.org/10.1097/PTS.0b013e318184a9d5; Reeve J, Maden M, Hill R, Turk A, Mahtani K, Wong G, et al. Deprescribing medicines in older people living with multimorbidity and polypharmacy: The TAILOR evidence synthesis. Health Technol Assess. 2022;26(32):1–148. https://doi.org/10.3310/AAFO2475; Patel TK, Patel PB, Bhalla HL, Dwivedi P, Bajpai V, Kishore S. Impact of suspected adverse drug reactions on mortality and length of hospital stay in the hospitalised patients: A meta-analysis. Eur J Clin Pharmacol. 2023;79(1):99–116. https://doi.org/10.1007/s00228-022-03419-7; Sandoval T, Martínez M, Miranda F, Jirón M. Incident adverse drug reactions and their effect on the length of hospital stay in older inpatients. Int J Clin Pharm. 2021;43(4):839–46. https://doi.org/10.1007/s11096-020-01181-3; Крысанова ВС, Крысанов ИС, Журавлева МВ, Гуревич КГ, Ермакова ВЮ. Оценка экономических затрат на нежелательные лекарственные реакции при проведении терапии. Фармация. 2018;67(8):44–50. https://doi.org/10.29296/25419218-2018-08-07; Buffone B, Lin YC, Grant J. β-lactam exposure outcome among patients with a documented allergy to penicillins post-implementation of a new electronic medical record system and alerting rules. J Assoc Med Microbiol Infect Dis Can. 2021;6(2):104–13. https://doi.org/10.3138/jammi-2020-0050; Butranova O, Zyryanov S, Gorbacheva A, Asetskaya I, Polivanov V. Drug-induced anaphylaxis: National database analysis. Pharmaceuticals. 2024;17(1):90. https://doi.org/10.3390/ph17010090; Zyryanov S, Asetskaya I, Butranova O, Terekhina E, Polivanov V, Yudin A, et al. Stevens–Johnson syndrome and toxic epidermal necro­ lysis: Analysis of the Russian database of spontaneous reports. Pharmaceuticals. 2024;17(6):675. https://doi.org/10.3390/ph17060675; Yu RJ, Krantz MS, Phillips EJ, Stone CA Jr. Emerging causes of drug-induced anaphylaxis: A review of anaphylaxis-associated reports in the FDA Adverse Event Reporting System (FAERS). J Allergy Clin Immunol Pract. 2021;9(2):819–29.e2. https://doi.org/10.1016/j.jaip.2020.09.021; Fei W, Shen J, Cai H. Causes of drug-induced severe cutaneous adverse reaction epidermal necrolysis (EN): An analysis using FDA Adverse Event Reporting System (FAERS) database. Clin Cosmet Investig Dermatol. 2023;16:2249–57. https://doi.org/10.2147/CCID.S422928; Kang SY, Seo J, Kang HR. Desensitization for the prevention of drug hypersensitivity reactions. Korean J Intern Med. 2022;37(2):261–70. https://doi.org/10.3904/kjim.2021.438; https://www.risksafety.ru/jour/article/view/481

Availability: https://www.risksafety.ru/jour/article/view/481
https://doi.org/10.30895/2312-7821-2025-481

Сравнительная оценка фармакоэкономической доступности блокаторов H1-гистаминовых рецепторов в г. Гомеле

Authors: Гришкова, П. В., Копытина, К. Ю, Яшина, Т. П.

Subject Terms: блокаторы H1-гистаминовых рецепторов, Гомель

Relation: Гришкова, П. В. Сравнительная оценка фармакоэкономической доступности блокаторов H1-гистаминовых рецепторов в г. Гомеле [Электронный ресурс] / П. В Гришкова, К. Ю Копытина, Т. П. Яшина // Проблемы и перспективы развития современной медицины : сб. науч. ст. XII Респ. науч.-практ. конф. с междунар. участием студентов и молодых ученых, Гомель, 8 окт. 2020 г. : в 8 т. / Гомел. гос. мед. ун-т; редкол. : А. Н. Лызиков [и др.]. – Гомель : ГомГМУ, 2020. – Т. 5. – С. 153–155. – 1 электрон. опт. диск (CD-ROM). Научные руководители: д.м.н., профессор Е. И. Михайлова; м.м.н. Т. П. Яшина; http://elib.gsmu.by/handle/GomSMU/7855

Availability: http://elib.gsmu.by/handle/GomSMU/7855