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1Academic Journal
Συγγραφείς: G. V. Mokrov, Г. В. Мокров
Πηγή: Pharmacokinetics and Pharmacodynamics; № 3 (2023); 3-11 ; Фармакокинетика и Фармакодинамика; № 3 (2023); 3-11 ; 2686-8830 ; 2587-7836
Θεματικοί όροι: биароматические соединения, cardioprotectors, β-adrenoreceptors blockers, biaromatic compounds, кардиопротекторы, блокаторы β-адренорецепторов
Περιγραφή αρχείου: application/pdf
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DOI:10.37489/2587-7836-2021-4-3-17.; Мокров Г.В. Кардиопротекторные средства с биароматической структурой. Часть 2. Блокаторы HCN-каналов. Фармакокинетика и Фармакодинамика. 2022;(2):3–10. DOI:10.37489/2587-7836-2022-2-03-10.; Мокров Г.В. Кардиопротекторные средства с биароматической структурой. Часть 3. Блокаторы натриевых каналов. Фармакокинетика и Фармакодинамика. 2022;(3):3–9. DOI:10.37489/2587-7836-2022-3-3-9; Мокров Г.В. Кардиопротекторные средства с биароматической структурой. Часть 4. Блокаторы и модуляторы калиевых hERG-каналов. Фармакокинетика и Фармакодинамика. 2022;(4):3–19. DOI:10.37489/2587-7836-2022-4-3-19.; Мокров Г.В. Кардиопротекторные средства с биароматической структурой. Часть 5. Блокаторы калиевых каналов Kv1.5. Фармакокинетика и Фармакодинамика. 2023;(2):3–13. DOI:10.37489/2587-7836-2023-2-3-13.; Howe R, Rao BS, Chodnekar MS. Beta-adrenergic blocking agents. VII. 2-(1,4-benzodioxanyl) and 2-chromanyl analogs of pronethalol (2-isopropylamino-1-(2-naphthyl)ethanol). J Med Chem. 1970 Mar;13(2): 169–176. DOI:10.1021/jm00296a001.; Van Lommen GRE, De Bruyn MFL, Schroven MFJ. US Patent 4654362 A. Published online October 12, 1984.; Van de Water A, Janssens W, Van Neuten J, et al. Pharmacological and hemodynamic profile of nebivolol, a chemically novel, potent, and selective beta 1-adrenergic antagonist. J Cardiovasc Pharmacol. 1988 May;11(5):552–563. DOI:10.1097/00005344-198805000-00007.; Mangrella M, Rossi F, Fici F, Rossi F. Pharmacology of nebivolol. Pharmacol Res. 1998 Dec;38(6):419-431. DOI:10.1006/phrs.1998.0387. PMID: 9990650.; Weiss R. Nebivolol: A Novel Beta-Blocker with Nitric Oxide-Induced Vasodilatation. Vasc Health Risk Manag. 2006;2(3):303. DOI:10.2147/VHRM.2006.2.3.303.; Olawi N, Krüger M, Grimm D, et al. Nebivolol in the treatment of arterial hypertension. Basic Clin Pharmacol Toxicol. 2019 Sep;125(3):189-201. 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Comparison of bevantolol and atenolol in chronic stable angina. Am J Cardiol. 1988 Jun 1;61(15):1204–1209. DOI:10.1016/0002-9149(88)91155-1.; Warner-lambert pipeline narrowed to 40 active research compounds: accupril (quinapril) nda submitted jan. 25; $80 Mil. budgetted for c-v work in 1989 : Pink Sheet. Published 1989. Accessed October 28, 2021. https://pink.pharmaintelligence.informa.com/ps015015/warnerlambert-pipelinenarrowed-to-40-active-research-compounds-accupril-quinapril-ndasubmitted-jan-25-80-mil-budgetted-for-cv-work-in-1989; Kreighbaum WE, Matier WL, Dennis RD, et al. Antihypertensive indole derivatives of phenoxypropanolamines with beta-adrenergic receptor antagonist and vasodilating activity. J Med Chem. 1980 Mar;23(3):285–289. DOI:10.1021/jm00177a015.; Hershberger RE, Wynn JR, Sundberg L, Bristow MR. Mechanism of action of bucindolol in human ventricular myocardium. J Cardiovasc Pharmacol. 1990;15(6):959–967. DOI:10.1097/00005344-199006000-00014.; Eichhorn EJ. Effects of bucindolol in heart failure. Am J Cardiol. 1993 Mar 25;71(9):65C-70C. DOI:10.1016/0002-9149(93)90089-u.; FDA rejects bucindolol and questions trial integrity. Published 2009. Accessed October 28, 2021. http://www.cardiobrief.org/2009/06/02/fdarejects-bucindolol-and-questions-trial-integrity/; Wiedemann F, Kampe W, Thiel M, Sponer G, Roesch E, Dietmann K. US Patent 4503067. Published online 1985. https://www.uspto.gov/web/offices/com/sol/foia/comm/pte/4503067.pdf; Ruffolo RR, Gellai M, Hieble JP, et al. The pharmacology of carvedilol. Eur J Clin Pharmacol. 1990;38 Suppl 2:S82-8. doi:10.1007/BF01409471.; Mctavish D, Campoli-Richards D, Sorkin EM, Doggrell SA. Carvedilol A Review of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Efficacy. Drugs. 1993;45(2):232–258. DOI:10.2165/00003495-199345020-00006.; Book WM. Carvedilol: A Nonselective β Blocking Agent With Antioxidant Properties. Congest Hear Fail. 2002;8(3):173–177, 190. 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Synthesis, β-adrenoceptor pharmacology and toxicology of S-(−)-1-(4-(2-ethoxyethoxy)phenoxy)-2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethylamino)propane hydrochloride, a short acting β1-specific antagonist. Eur J Med Chem. 2002;37(9):731-41. DOI:10.1016/S0223-5234(02)01399-5.; Mistry S, Daras E, Fromont C, et al. WO Patent 2021/004549 A1. Published online 2012.; Mistry SN, Baker JG, Fischer PM, et al. Synthesis and in Vitro and in Vivo Characterization of Highly β1-Selective β-Adrenoceptor Partial Agonists. J Med Chem. 2013;56(10):3852–3865. DOI:10.1021/jm400348g.; Baker JG, Fischer PM, Fromont C, et al. WO Patent 2021/104659 A1. Published online 2012.; Ghabbour HA, El-Bendary ER, El-Ashmawy MB, El-Kerdawy MM. Synthesis, Docking Study and β-Adrenoceptor Activity of Some New Oxime Ether Derivatives. Molecules. 2014;19(3):3417–3435. DOI:10.3390/molecules19033417.; https://www.pharmacokinetica.ru/jour/article/view/376
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2Academic Journal
Συγγραφείς: L. V. Topchieva, V. A. Korneva, I. E. Malysheva, Л. В. Топчиева, В. А. Корнева, И. Е. Малышева
Συνεισφορές: Исследования выполнялись в рамках выполнения НИР (№ 0218-2019-0077) ИБ КарНЦ РАН на научном оборудовании (НО) Центра коллективного пользования Федерального исследовательского центра «Карельский научный центр Российской академии наук»
Πηγή: Medical Immunology (Russia); Том 24, № 2 (2022); 273-282 ; Медицинская иммунология; Том 24, № 2 (2022); 273-282 ; 2313-741X ; 1563-0625
Θεματικοί όροι: кардиоселективные блокаторы β-адренорецепторов, adaptive immunity, T regulatory lymphocytes, T effector lymphocytes, gene expression, β-adrenergic receptor blockers, cardioselective, адаптивный иммунитет, Т-регуляторные лимфоциты, Т-эффекторные лимфоциты, экспрессия генов
Περιγραφή αρχείου: application/pdf
Relation: https://www.mimmun.ru/mimmun/article/view/2385/1522; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8693; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8694; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8695; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8696; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8697; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8698; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8699; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8700; https://www.mimmun.ru/mimmun/article/downloadSuppFile/2385/8701; Трушина Э.Н., Мустафина О.К., Хорхе С.С., Богданов А.Р., Сенцова Т.Б., Залетова Е.С., Кузнецов В.Д. Клеточный иммунитет у больных с артериальной гипертонией и ожирением // Вопросы питания, 2012. № 6. С. 19-26.; Фрейдлин И.С. Регуляторные Т-клетки: происхождение и функции // Медицинская иммунология, 2005. Т. 7, № 4. С. 347-354. doi:10.15789/1563-0625-2005-4-347-354.; Agabiti-Rosei C., Trapletti V., Piantoni S., Airò P., Tincani A., de Ciuceis C., Rossini C., Mittempergher F., Titi A., Portolani N., Caletti S., Coschignano M.A., Porteri E., Tiberio G.A.M., Pileri P., Solaini L., Kumar R., Ministrini S., Agabiti Rosei E., Rizzoni D. Decreased circulating T regulatory lymphocytes in obese patients undergoing bariatric surgery. PLoS One, 2018, Vol. 13, no. 5, 0197178. doi:10.1371/journal.pone.0197178.; Ba D., Takeichi N., Kodama T., Kobayashi H. Restoration of T cell depression and suppression of blood pressure in spontaneously hypertensive rats (SHR) by thymus grafts or thymus extracts. J. Immunol., 1982, Vol. 128, no. 3, pp. 1211-1216.; Barhoumi T., Kasal D.A., Li M.W., Shbat L., Laurant P., Neves M.F., Paradis P., Schiffrin E.L. T regulatory lymphocytes prevent angiotensin II-induced hypertension and vascular injury. Hypertension, 2011, Vol. 57, no. 3, pp. 469-476.; Belanger K.M., Crislip G.R., Gillis E.E., Abdelbary M., Musall J.B., Mohamed R., Baban B., Elmarakby A., Brands M.W., Sullivan J.C. Greater T regulatory cells in females attenuate DOCA-salt induced increases in blood pressure versus males. Hypertension, 2020, Vol. 75, no. 6, pp. 1615-1623.; Caillon A., Paradis P., Schiffrin E.L. Role of immune cells in hypertension. Br. J. Pharmacol., 2019, Vol. 176, no. 12, pp. 1818-1828.; Chiasson V.L., Talreja D., Young K.J., Chatterjee P., Banes-Berceli A.K., Mitchell B.M. FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertension. Hypertension, 2011, Vol. 57, no. 6, pp. 1167-1175.; Crislip G.R., Sullivan J.C. T-cell involvement in sex differences in blood pressure control. Clin. Sci. (Lond.), 2016, Vol. 130, no. 10, pp. 773-783.; Crowley S.D., Song Y.S., Lin E.E., Griffiths R., Kim H.S., Ruiz P. Lymphocyte responses exacerbate angiotensin II-dependent hypertension. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2010, Vol. 298, no. 4, pp. R1089-R1097.; de Ciuceis C., Rossini C., Airò P., Scarsi M., Tincani A., Tiberio G.A.M., Piantoni S., Porteri E., Solaini L., Duse S., Semeraro F., Petroboni B., Mori L., Castellano M., Gavazzi A., Agabiti Rosei C., Agabiti Rosei E., Rizzoni D. Relationship between different subpopulations of circulating CD4+ T-lymphocytes and microvascular structural alterations in humans. Am. J. Hypertens., 2017, Vol. 30, no. 1, pp. 51-60.; Gackowska L., Michałkiewicz J., Helmin-Basa A., Kłosowski M., Niemirska A., Obrycki Ł., Kubiszewska I., Wierzbicka A., Litwin M. Regulatory T-cell subset distribution in children with primary hypertension is associated with hypertension severity and hypertensive target organ damage. J. 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Jr., Saleh M.A., Nazarewicz R.R., Mikolajczyk T.P., Kaszuba A.M., Konior A., Prejbisz A., Januszewicz A., Norlander A.E., Chen W., Bonami R.H., Marshall A.F., Poffenberger G., Weyand C.M., Madhur M.S., Moore D.J., Harrison D.G., Guzik T.J. Activation of human T cells in hypertension: studies of humanized mice and hypertensive humans. Hypertension, 2016, Vol. 68, no. 1, pp. 123-132.; Ji Q., Cheng G., Ma N., Huang Y., Lin Y., Zhou Q., Que B., Dong J., Zhou Y., Nie S. Circulating Th1, Th2, and Th17 levels in hypertensive patients. Dis. Markers, 2017, Vol. 2017, 7146290. doi:10.1155/2017/7146290.; Katsuki M., Hirooka Y., Kishi T., Sunagawa K. Decreased proportion of Foxp3+ CD4+ regulatory T cells contributes to the development of hypertension in genetically hypertensive rats. J. Hypertens., 2015, Vol. 33, no. 4, pp. 773-783.; Khan M.M., Sansoni P., Silverman E.D., Engleman E.G., Melmon K.L. Beta-adrenergic receptors on human suppressor, helper, and cytolytic lymphocytes. Biochem. Pharmacol., 1986, Vol. 35, no. 7, pp. 1137-1142.; Kim C.H. FOXP3 and its role in the immune system. Adv. Exp. Med. Biol., 2009, Vol. 665, pp. 17-29.; Kim J.Y., Eunjo L., Koo S., Kim C.-W., Kim I. Transfer of Th17 from adult spontaneous hypertensive rats accelerates development of hypertension in juvenile spontaneous hypertensive rats. Biomed Res. Int., 2021, 6633825. doi:10.1155/2021/6633825.; Kohm A.P., Sanders V.M. Norepinephrine and beta 2-adrenergic receptor stimulation regulate CD4+ T and B lymphocyte function in vitro and in vivo. Pharmacol. Rev., 2001, Vol. 53, no. 4, pp. 487-525.; Koushki K., Shahbaz S. K., Mashayekhi K., MahvashSadeghi M., Zayeri Z.D., Taba M.Y., Banach M., AlRasadi K., Johnston T.P., Amirhossein Sahebkar A. Anti-inflammatory action of statins in cardiovascular disease: the role of inflammasome and toll-like receptor pathways. Clin. Rev. Allergy Immun., 2020, Vol. 60, no. 2, pp. 175-199.; Lee E., Kim N., Kang J., Yoon S., Lee H.A., Jung H., Kim S.H., Kim I. 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Adaptive immunity in hypertension. Curr. Hypertens. Rep., 2019, Vol. 21, no. 9, 68. doi:10.1007/s11906-019-0971-6.; Ni X., Wang A., Zhang L., Shan L.-Y., Zhang H.-C., Li L., Si J.-Q., Luo J., Li X.-Z., Ma K.-T. Up-regulation of gap junction in peripheral blood T lymphocytes contributes to the inflammatory response in essential hypertension. PLoS One, 2017, Vol. 12, no. 9, e0184773. doi:10.1371/journal.pone.0184773.; Pinto J.P., Dias V., Zoller H., Porto G., Carmo H., Carvalho F., de Sousa M. Hepcidin messenger RNA expression in human lymphocytes. Immunology, 2010, Vol. 130, no. 2, pp. 217-230.; Rai A., Narisawa M., Li P., Pia L., li Y., Yang G., Cheng X.W. Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications. J. Hypertens., 2020, Vol. 38, no. 10, pp. 1878-1889.; Renaudin C., Bataillard A., Sassard J. Partial transfer of genetic hypertension by lymphoid cells in Lyon rats. J. 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Cell Res., 2017, Vol. 358, no. 2, pp. 182-187.; https://www.mimmun.ru/mimmun/article/view/2385
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3Academic Journal
Συγγραφείς: Skybchyk, V. A.
Πηγή: Medicine of Ukraine; № 10(206) (2016); 34-41
Лекарства Украины; № 10(206) (2016); 34-41
Ліки України; № 10(206) (2016); 34-41Θεματικοί όροι: chronic heart failure, left ventricular ejection fraction, natriuretic peptide, beta-blockers, mineralocorticoid receptor antagonists, resynchronization therapy, хронічна серцева недостатність, фракція викиду лівого шлуночка, натрійуретичний пептид, блокатори β-адренорецепторів, антагоністи мінералокортикоїдних рецепторів, ресинхронізуюча терапія, 616.12. 085. 225.2, хроническая сердечная недостаточность, фракция выброса левого желудочка, натрийуретический пептид, блокаторы β-адренорецепторов, антагонисты минералокортикоидных рецепторов, ресинхронизирующая терапия, 3. Good health
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4Academic Journal
Συγγραφείς: Skybchyk, V. A.
Πηγή: Medicine of Ukraine; № 7-8(203-4) (2016); 15-18
Лекарства Украины; № 7-8(203-4) (2016); 15-18
Ліки України; № 7-8(203-4) (2016); 15-18Θεματικοί όροι: 616. 12-008. 46-08, hypertrophic cardiomyopathy, sudden cardiac death, risk stratification, β-blockers, septal myomectomy, гипертрофическая кардиомиопатия, стратификация риска, внезапная сердечная смерть, блокаторы β-адренорецепторов, септальная миомэктомия, гіпертрофічна кардіоміопатія, стратифікація ризику, раптова серцева смерть, блокатори β-адренорецепторів, септальна міомектомія, 3. Good health
Περιγραφή αρχείου: application/pdf
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5Academic Journal
Συγγραφείς: Kolesnyk, T. V.
Πηγή: Medicine of Ukraine; № 3(199) (2016); 24-31
Лекарства Украины; № 3(199) (2016); 24-31
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6Academic Journal
Συγγραφείς: Moshkovskaya, Y. О.
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