Search Results - "ЭКСПРЕССИЯ ГЕНОВ"

Source: VII Пущинская конференция «Биохимия, физиология и биосферная роль микроорганизмов», шко- ла-конференция для молодых ученых, аспирантов и студентов «Генетические технологии в микробио- логии и микробное разнообразие».

Subject Terms: синтон, фитостерин, метаболическая инженерия, биокаталитические свойства, миколицибактерии, гетерологическая экспрессия генов

8

Academic Journal

Характеристика Fur-зависимых некодирующих РНК у Pseudomonas putida BS3701

Source: VIII Пущинская конференция «Биохимия, физиология и биосферная роль микроорганизмов».

Subject Terms: БЕЛОК FUR, ЭКСПРЕССИЯ ГЕНОВ, КОНЦЕНТРАЦИЯ ЖЕЛЕЗА, ТРАНСКРИПЦИОННЫЙ РЕГУЛЯТОР

9

Academic Journal

Измерение эффективности терминаторов транскрипции в Rhodococcus с помощью флуоресцентных репортёров

Authors: Шемякина, A.O.

Source: VIII Пущинская конференция «Биохимия, физиология и биосферная роль микроорганизмов».

Subject Terms: БИОРЕМЕДИАЦИЯ, ФЛУОРЕСЦЕНТНЫЕ РЕПОРТЁРЫ, ЭКСПРЕССИЯ ГЕНОВ, ПРОМОТОР, ТЕРМИНАТОРЫ ТРАНСКРИПЦИИ, РОДОКОККИ

10

Academic Journal

Лантан-зависимая регуляция генов метанолдегидрогеназ Methylorubrum extorquens DM4

Source: VII Пущинская конференция «Биохимия, физиология и биосферная роль микроорганизмов», шко- ла-конференция для молодых ученых, аспирантов и студентов «Генетические технологии в микробио- логии и микробное разнообразие».

Subject Terms: лантаноиды, аэробные метилотрофные бактерии, метанол, экспрессия генов, энхансер, метанолдегидрогеназы, стресс-ответы бактерий, дихлорметан

11

Academic Journal

Сравнительная характеристика регуляторной области генов малых РНК PrrF

Source: Школа-конференция молодых ученых, аспирантов и студентов «Генетические технологии в микробиологии и микробное разнообразие».

Subject Terms: малые РНК, белок Fur, prrF, экспрессия генов, дефицит железа

12

Academic Journal

Конструирование праймеров к генам интереса, кодирующих аквапорины для проведения ПЦР

Source: VII Пущинская конференция «Биохимия, физиология и биосферная роль микроорганизмов», шко- ла-конференция для молодых ученых, аспирантов и студентов «Генетические технологии в микробио- логии и микробное разнообразие».

Subject Terms: экспрессия генов аквапоринов, симбиоз, засуха, арбускулярная микориза

13

Academic Journal

Expression of FOXO1, FOXO3 and BECN1 genes in peripheral blood leukocytes in chronic course of pulmonary sarcoidosis ; Экспрессия генов FOXO1, FOXO3 и BECN1 в лейкоцитах периферической крови при хроническом течении саркоидоза легких

Authors: Malysheva I.E., Balan O.V., Tikhonovich E.L.

Contributors: 0

Source: Russian Journal of Infection and Immunity; Vol 15, No 3 (2025); 582-586 ; Инфекция и иммунитет; Vol 15, No 3 (2025); 582-586 ; 2313-7398 ; 2220-7619

Subject Terms: pulmonary sarcoidosis, inflammation, FOXO transcription factors, autophagy, FOXO1, FOXO3, BECLN1, gene expression, саркоидоз легких, воспаление, транскрипционные факторы FOXO, аутофагия, экспрессия генов

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Availability: https://iimmun.ru/iimm/article/view/17856
https://doi.org/10.15789/2220-7619-IOF-17856

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14

Academic Journal

Modified lentiviral vector system for efficient delivery and long-term gene expression in human dendritic cells ; Модифицированная лентивирусная векторная система для эффективного введения и долговременной экспрессии генов в дендритных клетках человека

Authors: O. Yu. Piliutina, A. S. Voytehovich, E. G. Fomina, E. E. Grigorieva, I. K. Fomin, О. Ю. Пилютина, А. С. Войтехович, Е. Г. Фомина, Е. Е. Григорьева, И. К. Фомин

Contributors: The work was carried out with the financial support of the Ministry of Health of the Republic of Belarus (SPSR “Fundamental and Applied Sciences – Medicine”, 2016–2020, subprogram 2 “Diagnostics and Therapy of Diseases”, task 2.146 (Reg. No. 20200252, 2020), and SPSR “Biotechnology-2”, 2021–2025, subprogram “Molecular and Cellular Biotechnology-2”, task 1.14 (Reg. No. 20220282, 2022-2024)), Работа выполнена при финансовой поддержке Министерства здравоохранения Республики Беларусь (ГПНИ «Фундаментальные и прикладные науки – медицине», 2016–2020, подпрограмма 2 «Диагностика и терапия заболеваний», задание 2.146 (Рег. № 20200252, 2020 год) и ГПНИ «Биотехнология-2», 2021–2025, подпрограмма «Молекулярные и клеточные биотехнологии-2», задание 1.14 (Рег. № 20220282, 2022–2024 гг.))

Source: Doklady of the National Academy of Sciences of Belarus; Том 69, № 5 (2025); 404-415 ; Доклады Национальной академии наук Беларуси; Том 69, № 5 (2025); 404-415 ; 2524-2431 ; 1561-8323 ; 10.29235/1561-8323-2025-69-5

Subject Terms: экспрессия генов, lentiviral vectors, Vpx, dendritic cells, gene expression, лентивирусные векторы, дендритные клетки

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Relation: https://doklady.belnauka.by/jour/article/view/1275/1277; Steinman, R. M. Decisions about dendritic cells: past, present, and future / R. M. Steinman // Annual Review of Immunology. – 2012. – Vol. 30. – P. 1–22. https://doi.org/10.1146/annurev-immunol-100311-102839; Steinman, R. M. Taking dendritic cells into medicine / R. M. Steinman, J. Banchereau // Nature. – 2007. – Vol. 449. – P. 419–426. https://doi.org/10.1038/nature06175; Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity / P. J. Tacken, I. S. Zeelenberg, L. J. Cruz [et al.] // Blood. – 2011. – Vol. 118, N 26. – P. 6836–6844. https://doi.org/10.1182/blood-2011-07-367615; Naldini, L. Lentiviruses as gene transfer agents for delivery to non-dividing cells / L. Naldini // Current Opinion in Biotechnology. – 1998. – Vol. 9, N 5. – P. 457–463. https://doi.org/10.1016/s0958-1669(98)80029-3; SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates / H. Lahouassa, W. Daddacha, H. Hofmann [et al.] // Nature Immunology. – 2012. – Vol. 13. – P. 223–228. https://doi.org/10.1038/ni.2236; SAMHD1 is the dendriticand myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx / N. Laguette, B. Sobhian, N. Casartelli [et al.] // Nature. – 2011. – Vol. 474. – P. 654–657. https://doi.org/10.1038/nature10117; Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein / K. Hrecka, C. Hao, M. Gierszewska [et al.] // Nature. – 2011. – Vol. 474. – P. 658–661. https://doi.org/10.1038/nature10195; With a little help from a friend: increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIVMAC / C. Goujon, L. Jarrosson-Wuilleme, J. Bernaud [et al.] // Gene Therapy. – 2006. – Vol. 13. – P. 991–994. https://doi.org/10.1038/sj.gt.3302753; A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells / N. Manel, B. Hogstad, Ya. Wang [et al.] // Nature. – 2010. – Vol. 467. – P. 214–217. https://doi.org/10.1038/nature09337; Sambrook, J. F. Molecular cloning: a laboratory manual / J. Sambrook. – Cold Spring Harbor, 2001. – 3d ed.; A conserved dileucine-containing motif in p6gag governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIVmac and SIVagm / M. A. Accola, A. A. Bukovsky, M. S. Jones, H. G. Gottlinger // Journal of Virology. – 1999. – Vol. 73, N 12. – P. 9992–9999. https://doi.org/10.1128/JVI.73.12.9992-9999.1999; Solution structure of the human immunodeficiency virus type 1 p6 protein / T. Fossen, V. Wray, K. Bruns [et al.] // Journal of Biological Chemistry. – 2005. – Vol. 280, N 52. – P. 42515–42527. https://doi.org/10.1074/jbc.M507375200; Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1 / Q. Zhai, M. B. Landesman, H. Robinson [et al.] // Journal of Virology. – 2011. – Vol. 85, N 1. – P. 632–637. https://doi.org/10.1128/JVI.01683-10; Kondo, E. A conserved LXXLF sequence is the major determinant in p6gag required for the incorporation of human immunodeficiency virus type 1 Vpr / E. Kondo, H. G. Gottinger // Journal of Virology. – 1996. – Vol. 70, N 1. – P. 159–164. https://doi.org/10.1128/JVI.70.1.159-164.1996; Zhu, H. Identification of the 15FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion / H. Zhu, H. Jian, L. J. Zhao // Retrovirology. – 2004. – Vol. 1. – Art. 26. https://doi.org/10.1186/1742-4690-1-26; https://doklady.belnauka.by/jour/article/view/1275

Availability: https://doklady.belnauka.by/jour/article/view/1275
https://doi.org/10.29235/1561-8323-2025-69-5-404-415

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15

Academic Journal

Evaluation of the expression of FLG, AHR and ARNT genes in the skin of patients with atopic dermatitis after phototherapy ; Оценка экспрессии генов FLG, AHR и ARNT в коже больных атопическим дерматитом после фототерапии

Authors: Kozlova I.V., Chikin V.V., Gorodnichev P.V., Lagun K.M., Nosov N.Y.

Contributors: Ministry of Health of the Russian Federation as part of the implementation of the State task No. 056-00003-24-02 for 2024 and for the planning period of 2025 and 2026, approved on 03.07.2024., Минздрав России в рамках выполнения Государственного задания № 056-00003-24-02 на 2024 г. и на плановый период 2025 и 2026 гг., утвержденного 07.03.2024.

Source: Vestnik dermatologii i venerologii; Vol 101, No 1 (2025); 59-68 ; Вестник дерматологии и венерологии; Vol 101, No 1 (2025); 59-68 ; 2313-6294 ; 0042-4609 ; 10.25208/vdv.1011

Subject Terms: atopic dermatitis, narrow-band ultraviolet phototherapy, aryl hydrocarbon receptor, filaggrin, gene expression, атопический дерматит, узкополосная фототерапия, рецептор ароматических углеводородов, филаггрин, экспрессия генов

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Availability: https://vestnikdv.ru/jour/article/view/16839
https://doi.org/10.25208/vdv16839

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16

Academic Journal

Vitamin C content and profile of ascorbate metabolism gene expression in green leaves and bleached parts of the pseudostem of leek (Allium porrum L.) F1 hybrids ; Содержание витамина С и профиль экспрессии генов метаболизма аскорбата в зеленых листьях и отбеленной части ложного стебля гибридов F1 лука-порея (Allium porrum L.)

Authors: M. A. Filyushin, T. M. Seredin, A. V. Shchennikova, E. Z. Kochieva, М. А. Филюшин, Т. М. Середин, А. В. Щенникова, Е. З. Кочиева

Contributors: This research was funded by the Ministry of Science and Higher Education of the Russian Federation in accordance with agreement No. 075-15-2022-318 on April 20, 2022 on providing a grant in the form of subsidies from the Federal budget of the Russian Federation. The grant was provided as state support for the creation and development of a World-class Scientific Center “Agrotechnologies for the Future”.

Source: Vavilov Journal of Genetics and Breeding; Том 29, № 2 (2025); 200-209 ; Вавиловский журнал генетики и селекции; Том 29, № 2 (2025); 200-209 ; 2500-3259 ; 10.18699/vjgb-25-20

Subject Terms: экспрессия генов, Allium porrum L, vitamin C, ascorbate biosynthesis genes, ascorbate recycling genes, soluble sugars, gene expression, витамин С, гены биосинтеза аскорбата, гены рециклинга аскорбата, растворимые сахара

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Relation: https://vavilov.elpub.ru/jour/article/view/4538/1941; Ali B., Pantha S., Acharya R., Ueda Y., Wu L.-B., Ashrafuzzaman M., Ishizaki T., Wissuwa M., Bulley S., Frei M. Enhanced ascorbate level improves multi-stress tolerance in a widely grown indica rice variety without compromising its agronomic characteristics. J Plant Physiol. 2019;240:152998. doi 10.1016/j.jplph.2019.152998; Anisimova O.K., Seredin T.M., Shchennikova A.V., Kochieva E.Z., Filyushin M.A. Estimation of the vitamin C content and GDP-L-galactose phosphorylase gene (VTC2) expression level in leek (Allium porrum L.) cultivars. Russ J Plant Physiol. 2021a;68(1):85-93. doi 10.1134/S1021443720060023; Anisimova O.K., Shchennikova A.V., Kochieva E.Z., Filyushin M.A. Identification and variability of the GDP-L-galactose phosphosphorylase gene ApGGP1 in leek cultivars. Russ J Genet. 2021b;57(3): 311-318. doi 10.1134/S1021443720060023; Arrigoni O., De Tullio M.C. Ascorbic acid: much more than just an antioxidant. Biochim Biophys Acta. 2002;1569(1-3):1-9. doi 10.1016/s0304-4165(01)00235-5; Bernaert N. Bioactive compounds in leek (Allium ampeloprasum var. porrum): analysis as a function of the genetic diversity, harvest time and processing techniques. Doctoral dissertation. Ghent: Ghent University, 2013 Bernaert N., De Paepe D., Bouten C., De Clercq H., Stewart D., Van Bockstaele E., De Loose M., Van Droogenbroeck B. Antioxidant capacity, total phenolic and ascorbate content as a function of the genetic diversity of leek (Allium ampeloprasum var. porrum). Food Chem. 2012;134:669-677. doi 10.1016/j.foodchem.2012.02.159; Broad R.C., Bonneau J.P., Hellens R.P., Johnson A.A.T. Manipulation of ascorbate biosynthetic, recycling, and regulatory pathways for improved abiotic stress tolerance in plants. Int J Mol Sci. 2020; 21:1790. doi 10.3390/ijms21051790; Bulley S., Laing W. The regulation of ascorbate biosynthesis. Curr Opin Plant Biol. 2016;33:15-22. doi 10.1016/j.pbi.2016.04.010; Celebi-Toprak F., Alan A.R. In vitro gynogenesis in leek (Allium ampeloprasum L.). Methods Mol Biol. 2021;2287:171-184. doi 10.1007/978-1-0716-1315-3_7; Considine M.J., Foyer C.H. Redox regulation of plant development. Antioxid Redox Signal. 2014;21(9):1305-1326. doi 10.1089/ars.2013.5665; Dowdle J., Ishikawa T., Gatzek S., Rolinski S., Smirnoff N. Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling. Plant J. 2007;52:673-689. doi 10.1111/j.1365-313X.2007.03266.x; Feng H., Liu W., Zhang Q., Wang X., Wang X., Duan X., Li F., Huang L., Kang Z. TaMDHAR4, a monodehydroascorbate reductase gene participates in the interactions between wheat and Puccinia striiformis f. sp. tritici. Plant Physiol Biochem. 2014;76:7-16. doi 10.1016/j.plaphy.2013.12.015; Filyushin M.A., Anisimova O.K., Kochieva E.Z., Shchennikova A.V. Correlation of ascorbic acid content and the pattern of monodehydroascorbate reductases (MDHARs) gene expression in leek (Allium porrum L.). Russ J Plant Physiol. 2021;68(5):849-856. doi 10.1134/S1021443721050034; García G., Clemente-Moreno M.J., Díaz-Vivancos P., García M., Hernández J.A. The apoplastic and symplastic antioxidant system in onion: response to long-term salt stress. Antioxidants (Basel). 2020;12:67. doi 10.3390/antiox9010067; Gill S.S., Tuteja N. Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. Plant Physiol Biochem. 2010;48:909-930. doi 10.1016/j.plaphy.2010.08.016; Grzelak-Błaszczyk K., Kołodziejczyk K., Badełek E., Adamicki F. Changes in the contents of mono-, di- and oligosaccharides in leek plants stored in cold room. Eur Food Res Technol. 2011;232(6): 1027-1033. doi 10.1007/s00217-011-1476-y; Haroldsen V.M., Chi-Ham C.L., Kulkarni S., Lorence A., Bennett A.B. Constitutively expressed DHAR and MDHAR influence fruit, but not foliar ascorbate levels in tomato. Plant Physiol Biochem. 2011; 49:1244-1249. doi 10.1016/j.plaphy.2011.08.003; Hemilä H. Vitamin C and infections. Nutrients. 2017;9(4):339. doi 10.3390/nu9040339; Lanubile A., Maschietto V., De Leonardis S., Battilani P., Paciolla C., Marocco A. Defense responses to mycotoxin-producing fungi Fusarium proliferatum, F. subglutinans, and Aspergillus flavus in kernels of susceptible and resistant maize genotypes. Mol Plant Microbe Interact. 2015;28(5):546-557. doi 10.1094/MPMI-09-14-0269-R; Lemma E., Yusuf Z., Desta M., Seyida S., Idris M., Mengistu S., Teneshu J. Physicochemical properties and biological activities of garlic (Allium sativum L.) bulb and leek (Allium ampeloprasum L. var. porrum) leaf oil extracts. Sci World J. 2022;2022:6573754. doi 10.1155/2022/6573754; Leterrier M., Corpas F.J., Barroso J.B., Sandalio L.M., del Río L.A. Peroxisomal monodehydroascorbate reductase, genomic clone characterization and functional analysis under environmental stress conditions. Plant Physiol. 2005;138(4):2111-2123. doi 10.1104/pp.105.066225; Lundegårdh B., Botek P., Schulzov V., Hajslov J., Strömberg A., Andersson H.C. Impact of different green manures on the content of S-alk(en)yl-L-cysteine sulfoxides and L-ascorbic acid in leek (Allium porrum). J Agric Food Chem. 2008;56(6):2102-2111. doi 10.1021/jf071710s; Qi Q., Yanyan D., Yuanlin L., Kunzhi L., Huini X., Xudong S. Overexpression of SlMDHAR in transgenic tobacco increased salt stress tolerance involving S-nitrosylation regulation. Plant Sci. 2020;299: 110609. doi 10.1016/j.plantsci.2020.110609; Sultana S., Khew C.Y., Morshed M.M., Namasivayam P., Napis S., Ho C.L. Overexpression of monodehydroascorbate reductase from a mangrove plant (AeMDHAR) confers salt tolerance on rice. J Plant Physiol. 2012;169:311-318. doi 10.1016/j.jplph.2011.09.004; Swamy K.R.M., Gowda R.V. Leek and shallot. In: Peter K.V. (Ed.) Handbook of Herbs and Spices. Vol. 3. 2006;365-389. doi 10.1533/9781845691717.3.365; Yamada K., Osakabe Y. Sugar compartmentation as an environmental stress adaptation strategy in plants. Semin Cell Dev Biol. 2018;83: 106-114. doi 10.1016/j.semcdb.2017.12.015; Yoon J., Cho L.H., Tun W., Jeon J.S., An G. Sucrose signaling in higher plants. Plant Sci. 2021;302:110703. doi 10.1016/j.plantsci.2020.110703; Zhang Y., Li Z., Peng Y., Wang X., Peng D., Li Y., He X., Zhang X., Ma X., Huang L., Yan Y. Clones of FeSOD, MDHAR, DHAR genes from white clover and gene expression analysis of ROS-scavenging enzymes during abiotic stress and hormone treatments. Molecules. 2015;20:20939-20954. doi 10.3390/molecules201119741; https://vavilov.elpub.ru/jour/article/view/4538

Availability: https://vavilov.elpub.ru/jour/article/view/4538
https://doi.org/10.18699/vjgb-25-23

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17

Academic Journal

Violation of DNA methylation as a factor of fetal growth restriction ; Нарушение метилирования ДНК как фактор задержки развития плода

Authors: M. M. Gavrilenko, E. A. Trifonova, V. A. Stepanov, М. М. Гавриленко, Е. А. Трифонова, В. А. Степанов

Contributors: The study was carried out under the state assignment for fundamental research № 122020200083-8., Исследование выполнено за счет средств государственного задания по теме ФНИ № 122020200083-8.

Source: Medical Genetics; Том 24, № 2 (2025); 3-13 ; Медицинская генетика; Том 24, № 2 (2025); 3-13 ; 2073-7998

Subject Terms: патология беременности, methylation, gene expression, genome-wide studies, obstetric pathology, метилирование, экспрессия генов, полногеномные исследования

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Relation: https://www.medgen-journal.ru/jour/article/view/2607/1848; Spiers H., Hannon E., Schalkwyk L.C., et al. Methylomic trajectories across human fetal brain development. Genome research. 2015;25(3):338–352. DOI:10.1101/gr.180273.114; Zaletaev D.V., Nemtsova M.V., Strelnikov V.V., et al. Diagnostics of epigenetic alterations in hereditary and oncological disorders. Molecular biology. 2004;38(2): 174-182.; Law P.P., Holland M.L. DNA methylation at the crossroads of gene and environment interactions. Essays in biochemistry. 2019;63(6):717–726. DOI:10.1042/EBC20190031; Koukoura O., Sifakis S., Spandidos D.A. DNA methylation in the human placenta and fetal growth. Molecular medicine reports. 2012;5(4):883–889. DOI:10.3892/mmr.2012.763; Madeleneau D., Buffat C., Mondon F., et al. Transcriptomic analysis of human placenta in intrauterine growth restriction. Pediatric Research. 2015;77(6):799–807. DOI:10.1038/pr.2015.40; Ding Y., Cui H. 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18

Academic Journal

Маркеры воспалительного старения при гериатрических синдромах

Authors: Светлана Олеговна Лукьянова, Вячеслав Владимимрович Греченко, Ольга Владимировна Артемьева, Ирина Дмитриевна Стражеско, Людмила Викторовна Ганковская

Contributors: Исследование выполнено при поддержке гранта Российского научного фонда №23-15-00137, http://rscf.ru/project/23-15-00137/

Source: Medical Immunology (Russia); Online First ; Медицинская иммунология; Online First ; 2313-741X ; 1563-0625 ; 10.15789/1563-0625-0-0

Subject Terms: саркопения, долголетие, экспрессия генов, цитокины, синдром старческой астении

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19

Academic Journal

EXPRESSION OF THE ALKB AND MMOAA GENES IN RHODOCOCCUS CELLS IN THE PRESENCE OF C3–C16 N-ALKANES

Source: BIOAsia-Altai; Том 4 № 1 (2024): Международный биотехнологический форум «BIOAsia–Altai»; 108-112
BIOAsia-Altai; Vol 4 No 1 (2024): International Biotechnology Forum “BIOAsia-Altai”; 108-112

Subject Terms: н-алканы, биодеградация, пропанмонооксигеназа MmoA, алкан-1-монооксигеназы AlkB, актиномицеты рода Rhodococcus, gene expression, alkane-1-monooxygenases AlkB, n-alkanes, экспрессия генов, biodegradation, propane monooxygenase MmoA, actinomycetes of the genus Rhodococcus

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20

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Изучение эффективности ингибирования штаммами лактобациллразного вида продукции провоспалительных цитокинов эпителиальными клетками человека Caco-2, индуцированной Campylobacter jejuni

Subject Terms: interleukin, цитокины, кампилобактер, campylobacter, cytokine receptors, праймер, cytokines, 3. Good health, интерлейкин, primer, цитокиновые рецепторы, патоген, gene expression, экспрессия генов, pathogen

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