LTTR-зависимый промотор sgp-оперона функционирует в отсутствии транскрипционного активатора и эффектора

Source: Школа-конференция молодых ученых, аспирантов и студентов «Генетические технологии в микробиологии и микробное разнообразие».

Subject Terms: направленный мутагенез, гомологичная рекомбинация, Pseudomonas, РНК-полимераза, салицилат, регуляция экспрессии генов, промотор

Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins ; Компьютерный анализ особенностей регуляции гиперметилированных маркерных генов гепатокарциномы вирусными белками гепатита С

Authors: E. A. Antropova, T. M. Khlebodarova, P. S. Demenkov, A. S. Venzel, N. V. Ivanisenko, A. D. Gavrilenko, T. V. Ivanisenko, A. V. Adamovskaya, P. M. Revva, I. N. Lavrik, V. A. Ivanisenko, Е. А. Антропова, Т. М. Хлебодарова, П. С. Деменков, А. С. Вензель, Н. В. Иванисенко, А. Д. Гавриленко, Т. В. Иванисенко, А. В. Адамовская, П. М. Ревва, И. Н. Лаврик, В. А. Иванисенко

Contributors: The present study was supported by project No. 075-15-2021-944 of the Ministry of Science and Higher Education of the Russian Federation as a part of ERA-NET Target Identification and Drug Development in Liver Cancer (TAIGA).

Source: Vavilov Journal of Genetics and Breeding; Том 26, № 8 (2022); 733-742 ; Вавиловский журнал генетики и селекции; Том 26, № 8 (2022); 733-742 ; 2500-3259 ; 10.18699/VJGB-22-86

Subject Terms: биоинформатика, hepatitis C virus, expression regulation, methylation, regulatory pathways, gene networks, bioinformatics, вирус гепатита С, регуляция экспрессии, гиперметилирование, регуляторные пути, генные сети

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https://doi.org/10.18699/VJGB-22-89

The functional insight into the genetics of cardiovascular disease: results from the post-GWAS study ; Функциональный подход к изучению генетики сердечно-сосудистых заболеваний: post-GWAS исследование

Authors: L. O. Bryzgalov, E. E. Korbolina, I. S. Damarov, T. I. Merkulova, Л. О. Брызгалов, Е. Е. Корболина, И. С. Дамаров, Т. И. Меркулова

Source: Vavilov Journal of Genetics and Breeding; Том 26, № 1 (2022); 65-73 ; Вавиловский журнал генетики и селекции; Том 26, № 1 (2022); 65-73 ; 2500-3259 ; 10.18699/VJGB-22-01

Subject Terms: транскрипционные факторы, rSNPs, cardio-vascular disease risk, GWAS association, 1000 Genomes Project, gene expression regulation, transcription factor binding, регуляторные SNP, предрасположенность к сердечно-сосудистым заболеваниям, полногеномные исследования ассоциаций, проект «1000 геномов», регуляция экспрессии генов

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https://doi.org/10.18699/VJGB-22-10

MicroRNA role in hereditary genetic diseases ; Роль микроРНК в патогенезе наследственных заболеваний

Authors: O. M. Plotnikova, M. Yu. Skoblov, О. М. Плотникова, М. Ю. Скоблов

Source: Medical Genetics; Том 19, № 9 (2020); 5-17 ; Медицинская генетика; Том 19, № 9 (2020); 5-17 ; 2073-7998

Subject Terms: патогенез наследственных заболеваний, gene expression regulation, pathogenesis of hereditary diseases, регуляция экспрессии генов

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Relation: https://www.medgen-journal.ru/jour/article/view/1703/1339

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MicroRNAs and small interfering RNAs as tools for the directed regulation of cellular processes for cancer therapy ; МикроРНК и малые интерферирующие РНК как инструменты направленной регуляции клеточных процессов для терапии онкологических заболеваний

Authors: A. Komina V., S. Lavrentiev N., T. Ruksha G., А. Комина В., С. Лаврентьев Н., Т. Рукша Г.

Contributors: The publication was prepared with the support of a grant from the Russian Science Foundation (agreement No. 19-15-00110)., Публикация подготовлена при поддержке гранта Российского научного фонда (соглашение № 19-15-00110).

Source: Bulletin of Siberian Medicine; Том 19, № 1 (2020); 160-171 ; Бюллетень сибирской медицины; Том 19, № 1 (2020); 160-171 ; 1819-3684 ; 1682-0363 ; 10.20538/1682-0363-2020-19-1

Subject Terms: small non-coding RNA, gene expression regulation, target therapy, cancer, малые некодирующие РНК, регуляция экспрессии генов, направленная терапия, онкологические заболевания

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DOI:10.1016/j.omtn.2017.06.005.; https://bulletin.tomsk.ru/jour/article/view/2696

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https://doi.org/10.20538/1682-0363-2020-1-160-171

INTEGRATED MODULAR MODEL LINKING METABOLISM, SIGNALING TRANSDUCTION AND GENE EXPRESSION REGULATION INHUMAN SKELETAL MUSCLE

Source: XVII Российская конференция “Распределенные информационно-вычислительные ресурсы: Цифровые двойники и большие данные”.

Subject Terms: математическая модель, скелетная мышца, физическая нагрузка, РНК секвенирование, транскриптом, BioUML, RNA sequencing, регуляция экспрессии, Ca2+-dependent signaling pathway, Ca2+-зависимый сигнальный путь, physical exercise, regulation of expression, skeletal muscle, transcriptome, mathematical model

The role of HPV16 regulatory region methylation in viral oncogenes E6 and E7 eхpression in primary cervical cancer lesions ; Роль метилирования регуляторного района вируса папиллом человека типа 16 в экспрессии вирусных онкогенов Е6 и E7 в первичных опухолях шейки матки

Authors: Abramov P.M., Katargin A.N., Fedorova M.D., Kisseljova N.P., Pavlova L.S., Vinokurova S.V.

Source: Advances in Molecular Oncology; Vol 5, No 4 (2018); 110-116 ; Успехи молекулярной онкологии; Vol 5, No 4 (2018); 110-116 ; 2413-3787 ; 2313-805X

Subject Terms: human papillomavirus, cervical cancer, methylation, regulation of expression, viral oncogene E6, viral oncogenes E7, вирус папиллом человека, рак шейки матки, метилирование, регуляция экспрессии, вирусный онкоген E6, вирусный онкоген E7

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Relation: https://umo.abvpress.ru/jour/article/view/180/163; https://umo.abvpress.ru/jour/article/view/180

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https://doi.org/10.17650/2313-805X-2018-5-4-110-116

Influence of DNA-binding compounds with cancer preventive activity on the mechanisms of gene expression regulation ; Влияние ДНК-тропных антиканцерогенных соединений на механизмы регуляции экспрессии генов

Authors: Kirsanov K.I., Vlasova O.A., Fetisov T.I., Zenkov R.G., Lesovaya E.A., Belitsky G.A., Gurova K., Yakubovskaya M.G.

Contributors: Russian Science Foundation, grant 17-15-01526, Российский научный фонд, грант 17-15-01526

Source: Advances in Molecular Oncology; Vol 5, No 4 (2018); 41-63 ; Успехи молекулярной онкологии; Vol 5, No 4 (2018); 41-63 ; 2413-3787 ; 2313-805X

Subject Terms: DNA-tropic secondary plant metabolites, cancer preventive activity of natural small molecules, DNA intercalation, epigenetic regulation of gene expression, chromatin destabilization, ДНК-тропные вторичные метаболиты растений, антиканцерогенное действие природных низкомолекулярных соединений, интеркаляция ДНК, эпигенетическая регуляция экспрессии генов, дестабилизация хроматина

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https://doi.org/10.17650/2313-805X-2018-5-4-41-63

Generation of barcoded plasmid libraries for massively parallel analysis of chromatin position effects ; Создание штрихкодированных плазмидных библиотек для множественного одновременного анализа эффекта положения гена

Authors: M. O. Lebedev, L. A. Yarinich, A. V. Ivankin, A. V. Pindyurin, М. О. Лебедев, Л. А. Яринич, А. В. Иванкин, А. В. Пиндюрин

Source: Vavilov Journal of Genetics and Breeding; Том 23, № 2 (2019); 203-211 ; Вавиловский журнал генетики и селекции; Том 23, № 2 (2019); 203-211 ; 2500-3259

Subject Terms: культивируемые клетки дрозофилы, reporter construct, plasmid library, DNA cloning, Gibson assembly, massively parallel analysis, regulation of gene expression, regulatory DNA elements, chromatin position effects, cultured Drosophila cells, репортерная конструкция, плазмидная библиотека, клонирование ДНК, сборка методом Гибсона, множественный одновременный анализ, регуляция экспрессии генов, регуляторные элементы ДНК, эффект положения гена

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Availability: https://vavilov.elpub.ru/jour/article/view/1937
https://doi.org/10.18699/VJ19.483

МикроРНК: малые молекулы с большим значением

Source: Клиническая онкогематология, Vol 8, Iss 1 (2015)

Subject Terms: онкомаркеры, микроРНК, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, регуляция экспрессии, RC254-282

Access URL: https://doaj.org/article/fc22f46c8ad04cae9c5a37f15fd75b11

Differences in expression profiles in malingant melanoma patients according to immunotherapy response ; Особенности экспрессионного профиля больных злокачественной меланомой в зависимости от ответа на иммунотерапию

Authors: E. N. Lukyanova, M. S. Fedorova, E. A. Pudova, T. V. Nasedkina, E. V. Stepanova, K. M. Nyushko, A. Y. Popov, N. V. Koroban, A. A. Dmitriev, M. V. Kiseleva, A. V. Lipatova, A. S. Zasedatelev, A. V. Kudryavtseva, Е. Н. Лукьянова, М. С. Федорова, Е. А. Пудова, Т. В. Наседкина, Е. В. Степанова, К. М. Нюшко, А. Ю. Попов, Н. В. Коробан, А. А. Дмитриев, М. В. Киселева, А. В. Липатова, А. С. Заседателев, А. В. Кудрявцева

Source: Vavilov Journal of Genetics and Breeding; Том 21, № 8 (2017); 925-931 ; Вавиловский журнал генетики и селекции; Том 21, № 8 (2017); 925-931 ; 2500-3259

Subject Terms: регуляция экспрессии генов, immunotherapy, predictive biomarkers, NGS, miRNA profiling, transcriptomic analysis, regulation of gene expression, иммунотерапия, предиктивные маркеры, профилирование микроРНК, высокопроизводительное секвенирование, транскриптомный анализ

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Availability: https://vavilov.elpub.ru/jour/article/view/1281
https://doi.org/10.18699/VJ17.314

MuscleFANTOM - атлас экспрессии генов в скелетных мышцах человека

Authors: Низамов Шамиль Ринатович, Газизова Гузель Рашитовна, Шагимарданова Елена Ильясовна, Гусев Олег Александрович, Девятияров Руслан Мансурович, Хаяшизаки Йошихиде

Contributors: Институт фундаментальной медицины и биологии, Казанский федеральный университет

Subject Terms: CAGE, скелетные мышцы, регуляция экспрессии генов

Relation: СБОРНИК ТЕЗИСОВ XXIV СЪЕЗДА ФИЗИОЛОГИЧЕСКОГО ОБЩЕСТВА ИМ. И. П. ПАВЛОВА; http://dspace.kpfu.ru/xmlui/bitstream/net/177768/-1/Tezis_Nizamov_Sh._R.pdf; https://dspace.kpfu.ru/xmlui/handle/net/177768

Availability: https://dspace.kpfu.ru/xmlui/handle/net/177768

Новые функции рибосомных белков человека, выявленные с помощью методов, основанных на высокопроизводительном секвенировании

Contributors: Казанский (Приволжский) федеральный университет

Subject Terms: внерибосомные функции рибосомных белков, нерибосомные РНК-партнёры рибосомных белков, РНК-белковые взаимодействия, регуляция экспрессии генов, рибосомный профайлинг

Access URL: https://openrepository.ru/article?id=190706

Неканонические свойства рибосомного белка eL29 человека, проявляемые в регуляции экспрессии генов

Contributors: Казанский (Приволжский) федеральный университет

Subject Terms: РНК-белковые сшивки в клетках, рибосомный белок еL29, регуляция экспрессии генов на уровне трансляции, количественная ПЦР, рибосомный профайлинг, неканонические функции рибосомных белков

Access URL: https://openrepository.ru/article?id=190612

ОТ МЕДЛЕННЫХ К БЫСТРЫМ. ГИПОГРАВИТАЦИОННАЯ ПЕРЕСТРОЙКА МИОЗИНОВОГО ФЕНОТИПА МЫШЕЧНЫХ ВОЛОКОН

Authors: ШЕНКМАН Б.С.

Subject Terms: ГРАВИТАЦИОННАЯ РАЗГРУЗКА,ИЗОФОРМЫ ТЯЖЕЛЫХ ЦЕПЕЙ МИОЗИНА,МИОЗИНОВЫЙ ФЕНОТИП,РЕГУЛЯЦИЯ ЭКСПРЕССИИ МИОЗИНОВЫХ ГЕНОВ,СКЕЛЕТНАЯ МЫШЦА,ТИПЫ МЫШЕЧНЫХ ВОЛОКОН

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rSNP_Guide-BASED EVALUATION OF SNPs IN PROMOTеRS OF THE HUMAN APC AND MLH1 GENES ASSOCIATED WITH COLON CANCER ; ОЦЕНКА ПО ТЕХНОЛОГИИ rSNP_Guide SNPs ПРОМОТОРОВ ГЕНОВ АРС И МLH1 ЧЕЛОВЕКА, СВЯЗАННЫХ С РАКОМ ТОЛСТОГО КИШЕЧНИКА

Authors: D. A. Rasskazov, E. V. Antontseva, L. O. Bryzgalov, M. Yu. Matveeva, E. V. Kashina, P. M. Ponomarenko, G. V. Orlova, M. P. Ponomarenko, D. A. Afonnikov, T. I. Merkulova, Д. А. Рассказов, Е. В. Антонцева, Л. О. Брызгалов, М. Ю. Матвеева, Е. В. Кашина, П. М. Пономаренко, Г. В. Орлова, М. П. Пономаренко, Д. А. Афонников, Т. И. Меркулова

Contributors: Минобрнауки РФ, молодежный проект поддержки ведущих научных школ НШ-5278.2012.4, Президиум РАН

Source: Vavilov Journal of Genetics and Breeding; Том 17, № 4/1 (2013); 589-598 ; Вавиловский журнал генетики и селекции; Том 17, № 4/1 (2013); 589-598 ; 2500-3259

Subject Terms: t-тест Стьюдента, gene expression regulation, colon cancer, APC, MLH1 genes, DNA–regulatory protein complex, Student’s t-test, регуляция экспрессии генов, рак толстого кишечника, AРС, MLH1, комплекс ДНК с регуляторным белком

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Nо. 1/3. P. 25–33.; Antontseva E.V., Bryzgalov L.O., Matveeva M.Yu. et al. Search for regulatory SNPs associated with colon cancer in the APC and MLH1 genes // Russ. J. Genet: Appl. Res. 2012. V. 2. No. 3. P. 222–228.; Arasaradnam R.P., Quraishi M.N., Commane D. et al. MYOD-1 in normal colonic mucosa–role as a putative biomarker? // BMC Res. Notes. 2012. V. 5. P. 240.; Auerbach R.K., Chen B., Butte A.J. Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool // Bioinformatics. 2013. V. 29. Nо. 15. P. 1922–1924.; Belanger A.S., Tojcic J., Harvey M., Guillemette C. Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells // BMC Mol. Biol. 2010. V. 11. P. 9.; Berg O.G., von Hippel P.H. Selection of DNA binding sites by regulatory proteins, Statistical-mechanical theory and application to operators and promoters // J. Mol. Biol. 1987. V. 193. Nо. 4. P. 723–750.; Bruno M.E., West R.B., Schneeman T.A. et al. Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene // Mol. Immunol. 2004. V. 40. Nо. 10. P. 695–708.; Byrne A.M., Foran E., Sharma R. et al. Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells // Carcinogenesis. 2010. V. 31. Nо. 4. P. 737–744.; Chinnappan D., Xiao D., Ratnasari A. et al. Transcription factor YY1 expression in human gastrointestinal cancer cells // Int. J. Oncol. 2009. V. 34. Nо. 5. P. 1417–1423.; Christensen L.L., Tobiasen H., Holm A. et al. MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer // Int. J. Cancer. 2013. V. 133. Nо. 1. P. 67–78.; Gerstenblith M.R., Shi J., Landi M.T. Genome-wide association studies of pigmentation and skin cancer: a review and meta-analysis // Pigment Cell Melanoma Res. 2010. V. 23. Nо. 5. P. 587–606.; Groubet R., Pallet V., Delage B. et al. Hyperlipidic diets induce early alterations of the vitamin A signalling pathway in rat colonic mucosa // Endocr. Regul. 2003. V. 37. Nо. 3. P. 137–144.; Hamosh A., Scott A.F., Amberger J.S. et al. Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders // Nucl. Acids Res. 2005. V. 33. P. D514–D517.; Hindorff L.A., Sethupathy P., Junkins H.A. et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits // Proc. Natl Acad. Sci. USA. 2009. V. 106. Nо. 23. P. 9362–9367.; Hitchins M.P., Wong J.J.L., Suthers G. et al. Inheritance of a cancer-associated MLH1 germ-line epimutation // New Eng. J. Med. 2007. V. 356. Nо. 7. P. 697–705.; Kameue C., Tsukahara T., Ushida K. Alteration of gene expression in the colon of colorectal cancer model rat by dietary sodium gluconate // Biosci. Biotechnol. Biochem. 2006. V. 70. Nо. 3. P. 606–614.; Kolchanov N.A., Merkulova T.I., Ignatieva E.V. et al. Combined experimental and computational approaches to study the regulatory elements in eukaryotic genes // Brief Bioinform. 2007. V. 8. Nо. 4. P. 266–274.; Mulholland D.J., Dedhar S., Coetzee G.A., Nelson C.C. Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Want you like to know? // Endocrinol. Rev. 2005. V. 26. Nо. 7. P. 898–915.; NCBI Resource Coordinators, Database resources of the National Center for Biotechnology Information // Nucl. Acids Res. 2013. V. 41. P. D8–D20.; Oshchepkov D.Y., Vityaev E.E., Grigorovich D.A. et al. SITECON: a tool for detecting conservative conformational and physicochemical properties in transcription factor binding site alignments and for site recognition // Nucl. Acids Res. 2004. V. 32. Web Server issue. P. W208–W212.; Pare L., Marcuello E., Altes A. et al. Transcription factorbinding sites in the thymidylate synthase gene: predictors of outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin? // Pharmacogenomics J. 2008. V. 8. Nо. 5. P. 315–320.; Park S.H., Yu G.R., Kim W.H. et al. NF-Y-dependent cyclin B2 expression in colorectal adenocarcinoma // Clin. Cancer Res. 2007. V. 13. Nо. 3. P. 858–867.; Polakis P. An Introduction to Wnt Signaling // Targeting the Wnt Pathway in Cancer. N.Y.: Springer, 2011. Р. 1–18.; Ponomarenko J.V., Merkulova T.I., Vasiliev G.V. et al. rSNP_Guide, a database system for analysis of transcription factor binding to target sequences: application to SNPs and site-directed mutations // Nucl. Acids Res. 2001. V. 29. Nо. 1. P. 312–316.; Ponomarenko J.V., Orlova G.V., Merkulova T.I. et al. rSNP_ Guide: an integrated database-tools system for studying SNPs and site-directed mutations in transcription factor binding sites // Hum. Mutat. 2002. V. 20. Nо. 4. P. 239–248.; Ponomarenko M.P., Ponomarenko J.V., Frolov A.S. et al. Oligonucleotide frequency matrices addressed to recognizing functional DNA sites // Bioinformatics. 1999. V. 15. P. 631–643.; Ramsay R.G., Ciznadija D., Vanevski M., Mantamadiotis T. Transcriptional regulation of cyclo-oxygenase expression: three pillars of control // Int. J. Immunopathol. Pharmacol. 2003. V. 16. Nо. 2 (Suppl). P. 59–67.; Sanchez-Ruiz J.M. Protein kinetic stability // Biophys. Chem. 2010. V. 148. P. 1–15.; The International Human Genome Sequencing Consortium, Finishing the euchromatic sequence of the human genome // Nature. 2004. V. 431. Nо. 7011. P. 931–945.; Wai P.Y., Mi Z., Gao C. et al. Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells // J. Biol. Chem. 2006. V. 281. Nо. 28. P. 18973–18982.; Wei H.B., Han X.Y., Fan W. et al. Effect of retinoic acid on cell proliferation kinetics and retinoic acid receptor expression of colorectal mucosa // World J. Gastroenterol. 2003. V. 9. Nо. 8. P. 1725–1728.; Win A.K., Hopper J.L., Buchanan D.D. et al. Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers? // Eur. J. Cancer. 2013. V. 49. Nо. 7. P. 1578–1587.; Xu X.L., Yu J., Zhang H.Y. et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis // World J. Gastroenterol. 2004. V. 10. Nо. 23. P. 3441–3454.; https://vavilov.elpub.ru/jour/article/view/182

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BIOLOGICAL ROLE OF 8-OXO-2’-DEOXYGUANOSINE ; БИОЛОГИЧЕСКАЯ РОЛЬ 8-ОКСО-2’-ДЕЗОКСИГУАНОЗИНА

Authors: N. V. Marmiy, D. S. Esipov, Н. В. Мармий, Д. С. Есипов

Source: Vestnik Moskovskogo universiteta. Seriya 16. Biologiya; № 4 (2015); 19-23 ; Вестник Московского университета. Серия 16. Биология; № 4 (2015); 19-23 ; 0137-0952

Subject Terms: обзор, antioxidant, anti-inflammatory action, regulation of gene expression, DNA repair, review, антиоксидант, противовоспалительное действие, регуляция экспрессии генов, репарация

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Relation: https://vestnik-bio-msu.elpub.ru/jour/article/view/278/276; Kuchino Y., Mori F., Kasai H., Inoue H., Iwai S., Miura K., Ohtsuka E., Nishimura S. Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues // Nature. 1987. Vol. 327. N 6117. P. 77–79.; Johansen M.E., Muller J.G., Xu X., Burrows C.J. Oxidatively induced DNA-protein cross-linking between singlestranded binding protein and oligodeoxynucleotides containing 8-oxo-7,8-dihydro-2’-deoxyguanosine // Biochemistry. 2005. Vol. 44. N 15. P. 5660–5671.; Kawanishi S., Oikawa S. Mechanism of telomere shortening by oxidative stress // Ann. N.Y. Acad. Sci. 2004. Vol. 1019. P. 278–284.; Preston T.J., Henderson J.T., McCallum G.P., Wells P.G. Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2’-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs // Mol. Cancer. Ther. 2009. Vol. 8. N 7. P. 2015–2026.; Völker J., Plum G.E., Klump H.H., Breslauer K.J. Energetic coupling between clustered lesions modulated by intervening triplet repeat bulge loops: allosteric implications for DNA repair and triplet repeat expansion // Biopolymers. 2010. Vol. 93. N 4. P. 355–369.; Morero N.R., Argaraña C.E. Pseudomonas aeruginosa deficient in 8-oxodeoxyguanine repair system shows a high frequency of resistance to ciprofloxacin // FEMS Microbiol. Lett. 2009. Vol. 290. N 2. P. 217–226.; Garrido P., Mejia E., Garcia-Diaz M., Blanco L., Picher A.J. The active site of TthPolX is adapted to prevent 8-oxo-dGTP misincorporation // Nucleic Acids Res. 2014. Vol. 42. N 1. P. 534–543.; Delaney S., Jarem D.A., Volle C.B., Yennie C.J. Chemical and biological consequences of oxidatively damaged guanine in DNA // Free Radic. Res. 2012. Vol. 46. N 4. P. 420–441.; Dizdaroglu M. Oxidative damage to DNA in mammalian chromatin // Mutat. Res. 1992. Vol. 275. N 3–6. P. 331–342.; Svoboda P., Harms-Ringdahl M. Influence of chromatin structure and radical scavengers on yields of radiationinduced 8-oxo-dG and DNA strand breaks in cellular model systems // Radiat. Res. 2005. Vol. 164. N 3. P. 303–311.; Fleming A.M., Muller J.G., Dlouhy A.C., Burrows C.J. Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2’-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing // J. Am. Chem. Soc. 2012. Vol. 134. N 36. P. 15091–15102.; Michaels M.L., Cruz C., Grollman A.P., Miller J.H. Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged from of guanine in DNA // Proc Natl. Acad. Sci. USA. 1992. Vol. 89. N 15. P. 7022–7025.; Michaels M.L., Tchou J., Grollman А.P., Miller J.H. A repair system for 8-oxo-7,8-dihydrodeoxyguanine // Biochemistry. 1992. Vol. 31. N 45. P. 10964–10968.; Livingston A.L., O’Shea V.L., Kim T., Kool E.T., David S.S. Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY // Nat. Chem. Biol. 2008. Vol. 4. N 1. P. 51–58.; Nguyen K.V., Burrows C.J. A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair // J. Am. Chem. Soc. 2011. Vol. 133. P. 14586–14589.; Perillo B., Ombra M.N., Bertoni A., Cuozzo C., Sacchetti S., Sasso A., Chiariotti L., Malorni A., Abbondanza C., Avvedimento E.V. DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression // Science. 2008. Vol. 319. N 5860. P. 202–206.; Stebbeds W.J., Lunec J., Larcombe L.D. An in silico study of the differential effect of oxidation on two biologically relevant G-quadruplexes: possible implications in oncogene expression // PLoS One. 2012. Vol. 7. N 8. e43735.; Ma H., Zheng L., Li Y., Pan S., Hu J., Yu Z., Zhang G., Sheng G., Fu J. Triclosan reduces the levels of global DNA methylation in HepG2 cells // Chemosphere. 2013. Vol. 90. N 3. 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МИКРОРНК: МАЛЫЕ МОЛЕКУЛЫ С БОЛЬШИМ ЗНАЧЕНИЕМ

Authors: Аушев, Василий

Subject Terms: МИКРОРНК, РЕГУЛЯЦИЯ ЭКСПРЕССИИ, ОНКОМАРКЕРЫ

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WHEAT ANTIMICROBIAL PEPTIDES ; АНТИМИКРОБНЫЕ ПЕПТИДЫ ПШЕНИЦЫ

Authors: T. I. Odintsova, T. V. Korostyleva, L. L. Utkina, Ya. A. Andreev, A. A. Slavokhotova, E. A. Istomina, V. A. Pukhal’skii, T. A. Egorov, Т. И. Одинцова, Т. В. Коростылева, Л. Л. Уткина, Я. А. Андреев, А. А. Славохотова, Е. А. Истомина, В. А. Пухальский, Ц. А. Егоров

Contributors: гранты РФФИ № 09-04-00250-а и 11-04-00190-а, программа Президиума РАН «Генофонды и генетическое разнообразие», Госконтракт Минобрнауки № 16.512.11.2156

Source: Vavilov Journal of Genetics and Breeding; Том 16, № 1 (2012); 107-115 ; Вавиловский журнал генетики и селекции; Том 16, № 1 (2012); 107-115 ; 2500-3259

Subject Terms: регуляция экспрессии генов, Triticum kiharae Dorof. et Migusch, antimicrobial peptides, amino acid sequencing, 3′- and 5′-RАСЕ method, plant immunity, regulation of gene expression, антимикробные пептиды, секвенирование аминокислотных последовательностей, 3′- и 5′-RАСЕ, иммунитет растений

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THE ROLE OF SUGAR-RELATED REGULATION IN THE LIGHT-DEPENDENT ALTERATIONS OF ARABIDOPSIS GLUTAMATE DEHYDROGENASE GENES EXPRESSION

Authors: Garnik, E., Belkov, V., Tarasenko, V., Konstantinov, Yu

Subject Terms: ARABIDOPSIS THALIANA,ARABIDOPSIS MUTANTS,GLUTAMATE DEHYDROGENASE,HEXOKINASE 1,SUGAR SENSING AND SIGNALING, гексокиназа 1, глутаматдегидрогеназа, мутанты арабидопсиса, сахарозависимая регуляция экспрессии генов, Arabidopsis thaliana

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