Double-site rapid urease test versus histopathology for the diagnosis of Helicobacter pylori among patients with dyspepsia on proton pump inhibitors—A diagnostic accuracy study

Authors: Yadav, Ashutosh Ishan^Aff1, Jearth, Vaneet^{Aff1, IDs12664025017891_cor1}, Sharma, Arun Kumar^Aff1, Singh, Anupam Kumar^Aff1, Chauhan, Priya^Aff1, Patial, Purnima^Aff1, Sekar, Aravind^Aff2, Shah, Jimil^Aff1, Mandavdhare, Harshal^Aff1, Rana, Surinder Singh^Aff1, Dutta, Usha^Aff1

Source: Indian Journal of Gastroenterology. 45(4):706-714

Mucosal Brush Sampling Increases the Helicobacter pylori Detection Rate of the Rapid Urease Test: A Pilot Study

Authors: Chang Seok Bang, A In Choi, Jeong-Gyu Choi, Jae Jun Lee, Eun Jeong Gong

Source: Gut Liver

Subject Terms: Male, Adult, Helicobacter pylori, Biopsy, Pilot Projects, Middle Aged, Urease, Sensitivity and Specificity, Helicobacter Infections, Breath Tests, Gastric Mucosa, Humans, Original Article, Female, Aged

Access URL: https://pubmed.ncbi.nlm.nih.gov/41306096
https://pubmed.ncbi.nlm.nih.gov/41306096/
https://pmc.ncbi.nlm.nih.gov/articles/PMC12800670/
https://doi.org/10.5009/gnl250332

A Study on the Combined Application of Gastroscopy and the Rapid Urease Test in Paediatric Gastric Disorders.

Authors: Song X; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Lu H; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Zhao C; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Ma T; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Tian D; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Zhang G; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China.

Source: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2026 Apr; Vol. 36 (4), pp. 489-492.

Publication Type: Journal Article

Journal Info: Publisher: College of Physicians and Surgeons Pakistan Country of Publication: Pakistan NLM ID: 9606447 Publication Model: Print Cited Medium: Internet ISSN: 1681-7168 (Electronic) Linking ISSN: 1022386X NLM ISO Abbreviation: J Coll Physicians Surg Pak Subsets: MEDLINE

MeSH Terms: Helicobacter Infections*/diagnosis , Gastroscopy*/methods , Urease*/analysis , Urease*/metabolism , Helicobacter pylori*/isolation & purification , Stomach Diseases*/diagnosis , Stomach Diseases*/microbiology, Breath Tests/methods ; Humans ; Female ; Child ; Male ; Adolescent ; Child, Preschool ; Sensitivity and Specificity ; Biopsy ; China ; Rapid Diagnostic Tests ; ROC Curve

The Potential Role of the Rapid Urease Test with the Sweeping Method in the Gray Zone of the Urea Breath Test after Helicobacter pylori Eradication

Authors: Ji Hyun Kim, Ji Min Kim, Bumhee Park, Sun Gyo Lim, Sung Jae Shin, Kee Myung Lee, Gil Ho Lee, Choong-Kyun Noh

Source: Gut Liver
Gut and Liver, Vol 19, Iss 3, Pp 355-363 (2025)

Subject Terms: Male, Adult, Helicobacter pylori, RC799-869, Diseases of the digestive system. Gastroenterology, Middle Aged, Urease, Sensitivity and Specificity, Helicobacter Infections, Anti-Bacterial Agents, urea breath test, rapid urease test, sweeping method, eradication, urea breath test cutoff values, Breath Tests, Humans, Urea, Original Article, Female, False Negative Reactions, Retrospective Studies, Aged

Access URL: https://pubmed.ncbi.nlm.nih.gov/40169396
https://doaj.org/article/5533f80d00674751aee7313c42c5f02b

PCR outperforms rapid urease test in detecting Helicobacter pylori: A comparative study

Authors: Bharathi Panneerselvam, Madiha Abdul Majeed Abdul Nazer, Deepika Ilango

Source: Indian Journal of Microbiology Research. 13:142-147

Oral urease rapid test serve as an effective complement to the detection of Helicobacter pylori infection through urea breath test.

Authors: He Y; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Wang C; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Luo W; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China., Lin W; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Li S; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Xie F; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China., Zhou C; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Shen J; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China., Zou W; Nuclear Medicine Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Zhong J; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Wan Y; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China. wanyur@163.com., Zhao J; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China. zhaojinglin@jmszxyy.com.cn.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China. zhaojinglin@jmszxyy.com.cn.

Source: BMC gastroenterology [BMC Gastroenterol] 2025 Nov 28; Vol. 25 (1), pp. 846. Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

MeSH Terms: Helicobacter Infections*/diagnosis , Urease*/analysis , Helicobacter pylori*/isolation & purification, Breath Tests/methods ; Urea/analysis ; Dental Plaque/microbiology ; Tongue/microbiology ; Humans ; Sensitivity and Specificity ; Female ; Double-Blind Method ; Male ; Adult ; Predictive Value of Tests ; Middle Aged ; Rapid Diagnostic Tests ; Young Adult

Analytical performance evaluation of the Helibac rapid urease test for detection of Helicobacter pylori urease activity under controlled laboratory conditions

Authors: Anna Siwiec, Agnieszka Siwiec

Source: Frontiers in Microbiology, Vol 17 (2026)

Subject Terms: analytical performance, gastritis, Helicobacter pylori, culture, rapid urease test, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2026.1889913/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/a2b8cb6366b640f590915223acaaa6fa

COMPARISON OF RAPID UREASE TEST WITH IMMUNOHISTOCHEMICAL EXAMINATION OF GASTRIC MUCOSA SPECIMEN IN THE DIAGNOSTICS OF HELICOBACTER PYLORI INFECTION AMONG OUTPATIENTS

Authors: null Anna Bryczkowska, null Tomasz Arłukowicz, null Leszek Paweł Gromadziński

Source: Polish Journal of Natural Sciences. 40:181-190

Study of Prevalence of Gastritis Caused by H. pylori and Correlation of Urease Test with Serology (ELISA) Test

Authors: Maitreyi Ranjan, Hany Hameed, Shailesh Jain, Yogesh Garg, Roli Singh, Manjulika Tyagi, Romesh Jain

Source: J Pharm Bioallied Sci
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss Suppl 3, Pp S2081-S2084 (2024)

Subject Terms: RS1-441, 03 medical and health sciences, Pharmacy and materia medica, QD71-142, 0302 clinical medicine, gastritis, dyspepsia, Analytical chemistry, urease test, Original Research

Access URL: https://pubmed.ncbi.nlm.nih.gov/39346206
https://doaj.org/article/94567de364394a4fa420bb912c98c41b

Optimization of diagnosis of Helicobacter pylori infection: selective rapid urease tests and ammonium breath test

Authors: N. V. Baryshnikova, M. D. Lovchikova, I. I. Shishlova, L. V. Minaeva

Source: Medical alphabet. :8-12

Validity of rapid urease test using swab of gastric mucus to mucosal forceps and 13 C-urease breath test: a multicenter prospective observational study.

Authors: Yoshikawa T; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan. tk_yoshi@kuhp.kyoto-u.ac.jp., Yamauchi A; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan., Kou T; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan., Murao T; Department of Gastroenterology and Hepatology, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Okayama, Japan.; Department of Health Care Medicine, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Kamada T; Department of Health Care Medicine, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Suehiro M; Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Kawano K; Department of Gastroenterology and Hepatology, Hyogo Prefectural Awaji Medical Center, 1-1-137, Shioya, Sumoto City, 656-0021, Hyogo, Japan., Haruma K; Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Yazumi S; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Source: BMC gastroenterology [BMC Gastroenterol] 2024 Aug 09; Vol. 24 (1), pp. 258. Date of Electronic Publication: 2024 Aug 09.

Publication Type: Journal Article; Observational Study; Multicenter Study; Validation Study

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

MeSH Terms: Breath Tests*/methods , Breath Tests*/instrumentation , Helicobacter Infections*/diagnosis , Helicobacter Infections*/microbiology , Urease*/analysis , Urease*/metabolism , Helicobacter pylori*/isolation & purification , Helicobacter pylori*/enzymology , Sensitivity and Specificity*, Gastric Mucosa/microbiology ; Surgical Instruments/microbiology ; Humans ; Middle Aged ; Prospective Studies ; Male ; Female ; Aged ; Adult ; Aged, 80 and over ; Endoscopy, Digestive System ; Reproducibility of Results ; Carbon Isotopes

Accuracy of gastric nodule combined with rapid urease test prediction in diagnosing Helicobacter pylori infection in children

Authors: Wu, Hailin^Aff1, Zhou, Ying^{Aff1, IDs10096023047119_cor2}, Huang, Ying^{Aff1, IDs10096023047119_cor3}

Source: European Journal of Clinical Microbiology & Infectious Diseases. 43(3):481-487

Diagnosis of ‘‘Helicobacter pylori infection of the gastric biopsy’’ by rapid urease test, histopathology and Raman spectroscopy

Authors: Haider, Syed Iqbal ^a, Akhtar, Naeem ^a, Saleem, Muhammad ^b, Ahmed, Sheraz ^c, Nadeem, Shiza ^c, Amjad, Maham ^d, Ul Haq, Faiz ^{e, ⁎}

Source: In Diagnostic Microbiology & Infectious Disease January 2024 108(1)

Comparative diagnostic performance of rapid urease test with the sweeping method versus tissue sampling method after Helicobacter pylori eradication (with video).

Authors: Noh CK; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address: cknoh23@gmail.com., Lee GH; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea., Lee E; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA., Park B; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Republic of Korea., Lim SG; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea., Shin SJ; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea., Lee KM; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address: lkm5104@ajou.ac.kr.

Source: Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Oct; Vol. 100 (4), pp. 660-669.e3. Date of Electronic Publication: 2024 Apr 29.

Publication Type: Journal Article; Comparative Study; Video-Audio Media; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Mosby Yearbook Country of Publication: United States NLM ID: 0010505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6779 (Electronic) Linking ISSN: 00165107 NLM ISO Abbreviation: Gastrointest Endosc Subsets: MEDLINE

MeSH Terms: Helicobacter Infections*/diagnosis , Helicobacter Infections*/drug therapy , Helicobacter pylori*/isolation & purification , Urease*/analysis , Breath Tests*/methods , Sensitivity and Specificity*, Anti-Bacterial Agents/therapeutic use ; Gastric Mucosa/microbiology ; Gastric Mucosa/pathology ; Humans ; Male ; Female ; Middle Aged ; Adult ; ROC Curve ; Aged ; Logistic Models ; Polymerase Chain Reaction ; Biopsy

Concordance of the rapid urease test and the histopathology report in detecting Helicobacter pylori infection in a bariatric population. A retrospective cohort study

Authors: Piotr Panek, Justyna Rymarowicz, Miłosz Czeliński, Jakub Pośpiech, Marcin Dembiński, Marek Winiarski, Piotr Major, Michał Kukla

Source: Gastroenterology Review, Vol 20, Iss 4, Pp 395-399 (2025)

Subject Terms: gastritis, histopathology, helicobacter pylori, bariatric surgery, diagnostic test, esophagogastroscopy., Medicine

File Description: electronic resource

Relation: https://www.termedia.pl/Concordance-of-the-rapid-urease-test-and-the-histopathology-report-in-detecting-Helicobacter-pylori-infection-in-a-bariatric-population-A-retrospective-cohort-study,41,57223,1,1.html; https://doaj.org/toc/1895-5770; https://doaj.org/toc/1897-4317

Access URL: https://doaj.org/article/44c2f233a06240e6aad4058790e52e4c

Droplet Digital PCR-Based Detection of Clarithromycin Resistance on Rapid Urease Test Samples Predicts Helicobacter pylori Eradication Success: A New Zealand Cohort Study

Authors: Inns, Stephen James, Sowerbutts, Samantha, Yumnam, Bibek, Payne, Kate, Wheller, Georgina, Camberis, Mali, Mules, Thomas

Source: Helicobacter

Subject Terms: Male, Adult, Helicobacter pylori, Middle Aged, Polymerase Chain Reaction, Urease, Helicobacter Infections, Anti-Bacterial Agents, Cohort Studies, Treatment Outcome, Clarithromycin, Drug Resistance, Bacterial, Humans, Original Article, Female, New Zealand, Aged

Access URL: https://pubmed.ncbi.nlm.nih.gov/41013956

Development of a New Liquid Type Rapid Urease Test Kit (Helicotest®): Comparison with Other Commercial Kits

Authors: Hannah Lee, Hyo Sang Hwang, Jun-Won Chung, Kyeong Ah Kim, Seon Tae Kim

Source: Korean J Gastroenterol
The Korean Journal of Gastroenterology, Vol 81, Iss 5, Pp 209-215 (2023)

Subject Terms: Helicobacter pylori, diagnostic test kit, helicobacter pylori, Medicine, Humans, Original Article, Urease, 3. Good health

Access URL: https://pubmed.ncbi.nlm.nih.gov/37226821
https://pmc.ncbi.nlm.nih.gov/articles/PMC12094004/
https://doi.org/10.4166/kjg.2022.139
https://pubmed.ncbi.nlm.nih.gov/37226821/
https://doaj.org/article/dd45170e7b4748cd80a55c27003fdc6d

Comparative assessment of diagnostic accuracy: Helicobacter pylori stool antigen test versus rapid urease test in adult patients with upper gastrointestinal symptoms

Authors: Mohamed Fakhry, Khaled Abdelazeem, Mona M. Abdelmeguid, Mahmoud A. Abdelmaksoud, Emad Abdelrazzak, Omran M. Abdelmola, Safwat Salama, Waleed S. EL-Nasser, Maha Mohamed, Mohamed A. Younes, Amro M. Hassan

Source: Al-Azhar Assiut Medical Journal, Vol 22, Iss 2, Pp 110-117 (2024)

Subject Terms: rapid stool antigen test, helicobacter pylori, diagnostic accuracy, Internal medicine, RC31-1245

Access URL: https://doaj.org/article/cae9d5f807fb4cedb534f63920c9e848

Sodium, Potassium, Calcium and Magnesium Affect Colorimetric Changes of Rapid Urease Test: Implication on Helicobacter pylori Infection

Authors: Hangun Kim, Young-Chang Cho, Mijin Lee, Somy Yoon

Source: Yakhak Hoeji. 69:174-179

Performances diagnostiques du test rapide à l’uréase dans la détection de l’infection à Helicobacter pylori en période hémorragique

Accuracy of rapid urease test in the diagnosis of H. pylori during bleeding period

Authors: Lahmidani, N., Aqodad, N., ElYousfi, M., Mellouki, I., ElAbkari, M., Ibrahimi, A., Benajah, D.

Source: Acta Endoscopica. January 2013 43(1-2):14-18