Double-site rapid urease test versus histopathology for the diagnosis of Helicobacter pylori among patients with dyspepsia on proton pump inhibitors—A diagnostic accuracy study

Authors: Yadav, Ashutosh Ishan^Aff1, Jearth, Vaneet^{Aff1, IDs12664025017891_cor1}, Sharma, Arun Kumar^Aff1, Singh, Anupam Kumar^Aff1, Chauhan, Priya^Aff1, Patial, Purnima^Aff1, Sekar, Aravind^Aff2, Shah, Jimil^Aff1, Mandavdhare, Harshal^Aff1, Rana, Surinder Singh^Aff1, Dutta, Usha^Aff1

Source: Indian Journal of Gastroenterology. 45(4):706-714

Mucosal Brush Sampling Increases the Helicobacter pylori Detection Rate of the Rapid Urease Test: A Pilot Study

Authors: Chang Seok Bang, A In Choi, Jeong-Gyu Choi, Jae Jun Lee, Eun Jeong Gong

Source: Gut Liver

Subject Terms: Male, Adult, Helicobacter pylori, Biopsy, Pilot Projects, Middle Aged, Urease, Sensitivity and Specificity, Helicobacter Infections, Breath Tests, Gastric Mucosa, Humans, Original Article, Female, Aged

Access URL: https://pubmed.ncbi.nlm.nih.gov/41306096
https://pubmed.ncbi.nlm.nih.gov/41306096/
https://pmc.ncbi.nlm.nih.gov/articles/PMC12800670/
https://doi.org/10.5009/gnl250332

Helicobacter pylori and Symptomatic Cholelithiasis: Correlation Between Rapid Urease Testing and Histopathological Findings

Authors: Kesav Narayan S, Sailesh IS Kumar, Raja Vel Shantharam, Sivsankar Sivanandam, Ashok Nimmakanty Ramadas, Ashfaq Sulaiman Arif Abdul Rahuman, SakthiVel M

Source: Journal of Surgery Research and Practice. 7:1-7

A Study on the Combined Application of Gastroscopy and the Rapid Urease Test in Paediatric Gastric Disorders.

Authors: Song X; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Lu H; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Zhao C; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Ma T; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Tian D; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China., Zhang G; Department of Paediatrics, Maternity and Child Care Centre of Qinhuangdao, Qinhuangdao, China.

Source: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2026 Apr; Vol. 36 (4), pp. 489-492.

Publication Type: Journal Article

Journal Info: Publisher: College of Physicians and Surgeons Pakistan Country of Publication: Pakistan NLM ID: 9606447 Publication Model: Print Cited Medium: Internet ISSN: 1681-7168 (Electronic) Linking ISSN: 1022386X NLM ISO Abbreviation: J Coll Physicians Surg Pak Subsets: MEDLINE

MeSH Terms: Helicobacter Infections*/diagnosis , Gastroscopy*/methods , Urease*/analysis , Urease*/metabolism , Helicobacter pylori*/isolation & purification , Stomach Diseases*/diagnosis , Stomach Diseases*/microbiology, Breath Tests/methods ; Humans ; Female ; Child ; Male ; Adolescent ; Child, Preschool ; Sensitivity and Specificity ; Biopsy ; China ; Rapid Diagnostic Tests ; ROC Curve

The Potential Role of the Rapid Urease Test with the Sweeping Method in the Gray Zone of the Urea Breath Test after Helicobacter pylori Eradication

Authors: Ji Hyun Kim, Ji Min Kim, Bumhee Park, Sun Gyo Lim, Sung Jae Shin, Kee Myung Lee, Gil Ho Lee, Choong-Kyun Noh

Source: Gut Liver
Gut and Liver, Vol 19, Iss 3, Pp 355-363 (2025)

Subject Terms: Male, Adult, Helicobacter pylori, RC799-869, Diseases of the digestive system. Gastroenterology, Middle Aged, Urease, Sensitivity and Specificity, Helicobacter Infections, Anti-Bacterial Agents, urea breath test, rapid urease test, sweeping method, eradication, urea breath test cutoff values, Breath Tests, Humans, Urea, Original Article, Female, False Negative Reactions, Retrospective Studies, Aged

Access URL: https://pubmed.ncbi.nlm.nih.gov/40169396
https://doaj.org/article/5533f80d00674751aee7313c42c5f02b

PCR outperforms rapid urease test in detecting Helicobacter pylori: A comparative study

Authors: Bharathi Panneerselvam, Madiha Abdul Majeed Abdul Nazer, Deepika Ilango

Source: Indian Journal of Microbiology Research. 13:142-147

An integrated litmus test platform for low-background detection and photothermal inactivation of Salmonella typhimurium via HCR-urease signal amplification.

Authors: Kang Q; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China., Lin T; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China., Jiao J; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China., Du X; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address: xjdu@tust.edu.cn., Wang S; Tianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin 300071, China. Electronic address: wangshuo@nankai.edu.cn.

Source: Food chemistry [Food Chem] 2026 Oct 30; Vol. 527, pp. 150935. Date of Electronic Publication: 2026 Aug 27.

Publication Type: Journal Article; Evaluation Study

Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH Terms: Salmonella typhimurium*/genetics , Salmonella typhimurium*/isolation & purification , Salmonella typhimurium*/radiation effects , Salmonella typhimurium*/chemistry , Salmonella typhimurium*/enzymology , Salmonella typhimurium*/growth & development , Biosensing Techniques*/methods , Biosensing Techniques*/instrumentation , Urease*/chemistry , Bacterial Proteins*/genetics, Food Contamination/analysis ; Colorimetry/methods ; Nucleic Acid Hybridization/methods ; Food Microbiology/methods

Oral urease rapid test serve as an effective complement to the detection of Helicobacter pylori infection through urea breath test.

Authors: He Y; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Wang C; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Luo W; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China., Lin W; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Li S; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Xie F; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China., Zhou C; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Shen J; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China., Zou W; Nuclear Medicine Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Zhong J; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China., Wan Y; Gastroenterology Department of Panyu District Central Hospital, Guangzhou, Guangdong, China. wanyur@163.com., Zhao J; Gastrointestinal Surgery Department of Jiangmen Central Hospital, Jiangmen, Guangdong, China. zhaojinglin@jmszxyy.com.cn.; Digestive Disease Research Center of Jiangmen Central Hospital, Jiangmen, Guangdong, China. zhaojinglin@jmszxyy.com.cn.

Source: BMC gastroenterology [BMC Gastroenterol] 2025 Nov 28; Vol. 25 (1), pp. 846. Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

MeSH Terms: Helicobacter Infections*/diagnosis , Urease*/analysis , Helicobacter pylori*/isolation & purification, Breath Tests/methods ; Urea/analysis ; Dental Plaque/microbiology ; Tongue/microbiology ; Humans ; Sensitivity and Specificity ; Female ; Double-Blind Method ; Male ; Adult ; Predictive Value of Tests ; Middle Aged ; Rapid Diagnostic Tests ; Young Adult

Co-encapsulation of Au nanoclusters and carbon dots in ZIF with reversed acid-responsiveness for enhanced point-of-care testing of urease activity

Authors: Wang, Shun ^a, Li, Lei ^a, Sun, Guoming ^b, Wu, Zhina ^{c, ⁎}, Bai, Qian ^{a, ⁎⁎}, Wang, Mengke ^{b, ⁎⁎⁎}

Source: In Analytica Chimica Acta 15 January 2026 1383

Honeycomb-Inspired Surface-Enhanced Raman Scattering Microarray for Large-Area Automated Testing of Urease in Saliva Samples

Authors: Li, Guoqian^aff1, Fan, Jinkun^aff1, Zhang, Ting^aff1, Gao, Ting^aff1, Chong, Yuying^aff1, Liang, Minghui^aff1, Liang, Shijian^aff3, Hu, Bo^aff1, Yi, Langlang^aff1, Zhao, Lei^aff1, Castel, Helene^aff2

Source: ACS Sensors. 9(4):2031-2042

Availability: https://pubs.acs.org/doi/10.1021/acssensors.4c00006

Analytical performance evaluation of the Helibac rapid urease test for detection of Helicobacter pylori urease activity under controlled laboratory conditions

Authors: Anna Siwiec, Agnieszka Siwiec

Source: Frontiers in Microbiology, Vol 17 (2026)

Subject Terms: analytical performance, gastritis, Helicobacter pylori, culture, rapid urease test, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2026.1889913/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/a2b8cb6366b640f590915223acaaa6fa

COMPARISON OF RAPID UREASE TEST WITH IMMUNOHISTOCHEMICAL EXAMINATION OF GASTRIC MUCOSA SPECIMEN IN THE DIAGNOSTICS OF HELICOBACTER PYLORI INFECTION AMONG OUTPATIENTS

Authors: null Anna Bryczkowska, null Tomasz Arłukowicz, null Leszek Paweł Gromadziński

Source: Polish Journal of Natural Sciences. 40:181-190

Study of Prevalence of Gastritis Caused by H. pylori and Correlation of Urease Test with Serology (ELISA) Test

Authors: Maitreyi Ranjan, Hany Hameed, Shailesh Jain, Yogesh Garg, Roli Singh, Manjulika Tyagi, Romesh Jain

Source: J Pharm Bioallied Sci
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss Suppl 3, Pp S2081-S2084 (2024)

Subject Terms: RS1-441, 03 medical and health sciences, Pharmacy and materia medica, QD71-142, 0302 clinical medicine, gastritis, dyspepsia, Analytical chemistry, urease test, Original Research

Access URL: https://pubmed.ncbi.nlm.nih.gov/39346206
https://doaj.org/article/94567de364394a4fa420bb912c98c41b

Optimization of diagnosis of Helicobacter pylori infection: selective rapid urease tests and ammonium breath test

Authors: N. V. Baryshnikova, M. D. Lovchikova, I. I. Shishlova, L. V. Minaeva

Source: Medical alphabet. :8-12

Validity of rapid urease test using swab of gastric mucus to mucosal forceps and 13 C-urease breath test: a multicenter prospective observational study.

Authors: Yoshikawa T; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan. tk_yoshi@kuhp.kyoto-u.ac.jp., Yamauchi A; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan., Kou T; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan., Murao T; Department of Gastroenterology and Hepatology, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Okayama, Japan.; Department of Health Care Medicine, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Kamada T; Department of Health Care Medicine, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Suehiro M; Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Kawano K; Department of Gastroenterology and Hepatology, Hyogo Prefectural Awaji Medical Center, 1-1-137, Shioya, Sumoto City, 656-0021, Hyogo, Japan., Haruma K; Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan., Yazumi S; Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Source: BMC gastroenterology [BMC Gastroenterol] 2024 Aug 09; Vol. 24 (1), pp. 258. Date of Electronic Publication: 2024 Aug 09.

Publication Type: Journal Article; Observational Study; Multicenter Study; Validation Study

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

MeSH Terms: Breath Tests*/methods , Breath Tests*/instrumentation , Helicobacter Infections*/diagnosis , Helicobacter Infections*/microbiology , Urease*/analysis , Urease*/metabolism , Helicobacter pylori*/isolation & purification , Helicobacter pylori*/enzymology , Sensitivity and Specificity*, Gastric Mucosa/microbiology ; Surgical Instruments/microbiology ; Humans ; Middle Aged ; Prospective Studies ; Male ; Female ; Aged ; Adult ; Aged, 80 and over ; Endoscopy, Digestive System ; Reproducibility of Results ; Carbon Isotopes

Accuracy of gastric nodule combined with rapid urease test prediction in diagnosing Helicobacter pylori infection in children

Authors: Wu, Hailin^Aff1, Zhou, Ying^{Aff1, IDs10096023047119_cor2}, Huang, Ying^{Aff1, IDs10096023047119_cor3}

Source: European Journal of Clinical Microbiology & Infectious Diseases. 43(3):481-487

Urease Breath Test for Rapid Characterization of Pneumonia

Authors: Avisa Pharma Inc., Malvern Consulting Group, Inc.

Contributors: Justin T Baca, Assistant Professor of Emergency Medicine

Source: A Phase 1, Open-label, Evaluation of a 13C-urea Breath Test for the Detection of Urease-producing Bacteria in Patients Diagnosed With Pneumonia in the Emergency Department

Sitagliptin attenuates urease-associated phenotypes and potentiates meropenem in multidrug-resistant Gram-negative clinical isolates: a preliminary repurposing study.

Authors: Eladl A; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt., Abbas HA; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt., Abd El-Hamid MI; Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt., Elbaramawi SS; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt., Noureldin NA; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt., Nazeih SI; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2026 Oct 06; Vol. 81 (11).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

MeSH Terms: Anti-Bacterial Agents*/pharmacology , Thienamycins*/pharmacology , Thienamycins*/metabolism , Urease*/metabolism , Urease*/antagonists & inhibitors , Sitagliptin Phosphate*/pharmacology , Gram-Negative Bacteria*/drug effects , Gram-Negative Bacteria*/enzymology , Gram-Negative Bacteria*/isolation & purification , Enzyme Inhibitors*/pharmacology , Drug Resistance, Multiple, Bacterial*, Meropenem/pharmacology ; Animals ; Microbial Sensitivity Tests ; Drug Synergism ; Chlorocebus aethiops ; Humans ; Vero Cells ; Drug Repositioning ; Gene Expression Profiling ; Phenotype

Diagnosis of ‘‘Helicobacter pylori infection of the gastric biopsy’’ by rapid urease test, histopathology and Raman spectroscopy

Authors: Haider, Syed Iqbal ^a, Akhtar, Naeem ^a, Saleem, Muhammad ^b, Ahmed, Sheraz ^c, Nadeem, Shiza ^c, Amjad, Maham ^d, Ul Haq, Faiz ^{e, ⁎}

Source: In Diagnostic Microbiology & Infectious Disease January 2024 108(1)

Comparative diagnostic performance of rapid urease test with the sweeping method versus tissue sampling method after Helicobacter pylori eradication (with video).

Authors: Noh CK; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address: cknoh23@gmail.com., Lee GH; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea., Lee E; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA., Park B; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Republic of Korea., Lim SG; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea., Shin SJ; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea., Lee KM; Current affiliations: Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address: lkm5104@ajou.ac.kr.

Source: Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Oct; Vol. 100 (4), pp. 660-669.e3. Date of Electronic Publication: 2024 Apr 29.

Publication Type: Journal Article; Comparative Study; Video-Audio Media; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Mosby Yearbook Country of Publication: United States NLM ID: 0010505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6779 (Electronic) Linking ISSN: 00165107 NLM ISO Abbreviation: Gastrointest Endosc Subsets: MEDLINE

MeSH Terms: Helicobacter Infections*/diagnosis , Helicobacter Infections*/drug therapy , Helicobacter pylori*/isolation & purification , Urease*/analysis , Breath Tests*/methods , Sensitivity and Specificity*, Anti-Bacterial Agents/therapeutic use ; Gastric Mucosa/microbiology ; Gastric Mucosa/pathology ; Humans ; Male ; Female ; Middle Aged ; Adult ; ROC Curve ; Aged ; Logistic Models ; Polymerase Chain Reaction ; Biopsy