SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and associations with humoral responses

Authors: Tim R. Mosmann, Jonathan A. Rebhahn, Stephen C. De Rosa, Michael C. Keefer, M. Juliana McElrath, Nadine G. Rouphael, Giuseppe Pantaleo, Peter B. Gilbert, Lawrence Corey, James J. Kobie, Juilee Thakar

Source: Front Immunol
Frontiers in Immunology, Vol 15 (2024)
Frontiers in immunology, vol. 15, pp. 1347926

Subject Terms: CD4-Positive T-Lymphocytes, 0301 basic medicine, T cell antibody correlation, HIV - human immunodeficiency virus, Immunology, reanalysis, HIV Infections, HIV Antibodies, Humans, AIDS Vaccines/immunology, CD4-Positive T-Lymphocytes/immunology, Flow Cytometry/methods, Cluster Analysis, HIV Infections/immunology, HIV Infections/virology, Cytokines/metabolism, Cytokines/immunology, Immunity, Humoral, HIV Antibodies/immunology, HIV Antibodies/blood, HIV-1/immunology, Vaccines, DNA/immunology, Interleukins/immunology, T cell response, algorithmic flow cytometry analysis, vaccine trial, 03 medical and health sciences, Vaccines, DNA, AIDS Vaccines, 0303 health sciences, Interleukins, RC581-607, Flow Cytometry, 3. Good health, HIV-1, Cytokines, Immunologic diseases. Allergy

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