Molecular Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs

Authors: Arias de la Rosa, Iván, Escudero-Contreras, Alejandro, Ruiz-Ponce, Miriam, Román-Rodríguez, Cristóbal, Pérez-Sánchez, Carlos, Ábalos-Aguilera, María del Carmen, Ortega-Castro, Rafaela, Alcaide, Juan, Murri, Mora, Font, Pilar, Calvo-Gutiérrez, Jerusalem, Luque-Tevar, Maria, Patiño-Trives, Alejandra Maria, Guzmán-Ruiz, Rocío, Malagón, Maria del Mar, Tinahones, Francisco José, Collantes-Estévez, Eduardo, López-Pedrera, Chary, Barbarroja, Nuria

Contributors: Arias de la Rosa,I, Escudero-Contreras,A, Ruiz-Ponce,M, Román-Rodríguez,C, Pérez-Sánchez,C, Ábalos-Aguilera,MC, Ortega-Castro,R, Font,P, Calvo-Gutiérrez,J, Luque-Tevar,M, Patiño-Trives,AM, Collantes-Estévez,E, López-Pedrera,C, Barbarroja,N Rheumatology Service/Deparment of Medicine and Surgical Sciences, Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), University of Cordoba, Reina Sofia Hospital, Cordoba, Spain. Alcaide,J, Murri,M, Tinahones,FJ Biomedical Research Institute (IBIMA), Service of Endocrinology and Nutrition, Malaga Hospital Complex, Virgen de la Victoria, Malaga, Spain. Alcaide,J, Malagón,MM, Tinahones,FJ Centros de Investigació n Biomédica en Red (CIBER) Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. Guzmán-Ruiz,R, Malagón,MM Department of Cell Biology, Physiology and Immunology, Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain., This research was funded by grants from the Instituto de Salud Carlos III (PI17/01316 and PI18/00837), co-financed by the European Regional Development Fund (ERDF), a way to make Europe, Spain, MINECO (RyC-2017-23437), and the Spanish Inflammatory and Rheumatic diseases Network (RIER, RD16/0012/0015). CL-P was supported by a contract from the Junta de Andalucia (Nicolas Monardes programme).

Subject Terms: Rheumatoid arthritis, Obesity, Inflammation, Adipose tissue, cDMARDs, Leflunomide, Hydroxychloroquine, Methotrexate, Artritis reumatoide, Obesidad, Inflamación, Tejido adiposo, Antirreumáticos, Leflunomida, Hidroxicloroquina, Metotrexato, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Persons::Persons::Age Groups::Adult, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antirheumatic Agents, Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases::Arthritis, Rheumatoid, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity

File Description: application/pdf

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.744022/full; Arias de la Rosa I, Escudero-Contreras A, Ruiz-Ponce M, Román-Rodríguez C, Pérez-Sánchez C, Ábalos-Aguilera MDC, et al. Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs. Front Immunol. 2021 Oct 13;12:744022; http://hdl.handle.net/10668/4179; PMC8549628

Availability: http://hdl.handle.net/10668/4179
https://doi.org/10.3389/fimmu.2021.744022

Altered Proteomic Profile of Adipose Tissue-Derived Mesenchymal Stem Cell Exosomes from Cats with Severe Chronic Gingivostomatitis

Authors: Villatoro, Antonio J., Martín-Astorga, María del Carmen, Alcoholado, Cristina, Cárdenas, Casimiro, Fariñas, Fernando, Becerra, José, Visser, Rick

Contributors: Villatoro,AJ, Martín-Astorga,MC, Alcoholado,C, Becerra,J, Visser,R Laboratory of Bioengineering and Tissue Regeneration, Department of Cell Biology, Genetics and Physiology, University of Málaga, IBIMA, Málaga, Spain. Villatoro,AJ Instituto de Inmunología Clínica y Terapia Celular (IMMUNESTEM), Málaga, Spain. Cárdenas,C Research Support Central Services (SCAI) of the University of Málaga, Málaga, Spain. Fariñas,F Grupo Ynmun, Spanish Association for the Research in Immunological and Infectious Diseases, Málaga, Spain. Becerra,J, Visser,R Biomedical Research Networking Center in Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), Madrid, Spain. Becerra,J, Visser,R Andalusian Centre for Nanomedicine and Biotechnology-University of Málaga (BIONAND), Málaga, Spain., This research was funded by Instituto de Salud Carlos III (Red TerCel), grant number “RD16/0011/0022”, Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía, grant number “UMA18-FEDERJA-133”, Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, grant number “VI National R&D&I Plan 2008–2011”, Ministerio de Ciencia, Innovación y Universidades, grant number “PEJ2018-004785-A”.

Subject Terms: Feline, Feline chronic gingivostomatitis, Mesenchymal stem cells, Exosomes, Ultra-highperformance liquid chromatography high-resolution mass spectrometry (UHPLC–HRMS), Enfermedades de los gatos, Células madre mesenquimatosas, Exosomas, Cromatografía líquida de alta presión, Espectrometría de masas, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Carnivora::Felidae::Felis::Cats, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Transport Vesicles::Exosomes, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Control Groups, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Down-Regulation, Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genetic Research::Gene Ontology, Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biochemistry::Proteomics, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Caliciviridae Infections, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Communication, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry, Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System

File Description: application/pdf; image/tiff; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Relation: https://www.mdpi.com/2076-2615/11/8/2466/htm; Villatoro AJ, Martín-Astorga MC, Alcoholado C, Cárdenas C, Fariñas F, Becerra J, et al. Altered Proteomic Profile of Adipose Tissue-Derived Mesenchymal Stem Cell Exosomes from Cats with Severe Chronic Gingivostomatitis. Animals. 2021 Aug 23;11(8):2466; http://hdl.handle.net/10668/4117; PMC8388770

Availability: http://hdl.handle.net/10668/4117
https://doi.org/10.3390/ani11082466

Implementation of a Physical Activity Program Protocol in Schoolchildren: Effects on the Endocrine Adipose Tissue and Cognitive Functions

Authors: Diaz-Castro, Javier, Garcia-Vega, Jose Eulogio, Ochoa, Julio J., Puche-Juarez, María, Toledano, Juan M., Moreno-Fernandez, Jorge

Contributors: Diaz-Castro,J, Garcia-Vega,JE, Ochoa,JJ, Puche-Juarez,M, Toledano,JM, Moreno-Fernandez,J Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, Granada, Spain. Diaz-Castro,J, Moreno-Fernandez,J Institute of Nutrition and Food Technology “José Mataix Verdú”, University of Granada, Granada, Spain. Diaz-Castro,J Instituto de Investigación Biosanitaria (IBS), Granada, Spain. Garcia-Vega,JE Nutrition and Food Sciences Ph.D. Program, University of Granada, Granada, Spain., JM-F was supported by a Postdoctoral Contract (Perfeccionamiento de Doctores) from the University of Granada.

Subject Terms: Children, Physical activity, Anthropometry, Diet, Adipose tissue, Cognitive function, Niño, Ejercicio físico, Antropometría, Dieta, Tejido adiposo, Cognición, Medical Subject Headings::Persons::Persons::Age Groups::Adolescent, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Adipokines::Adiponectin, Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Quality of Life, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Nerve Growth Factors::Brain-Derived Neurotrophic Factor, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Complement Activating Enzymes::Complement Factor D, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Membrane Glycoproteins::Fibronectins, Sociology and Social Phenomena::Education::Education, Nonprofessional::Physical Education and Training, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Composition, Medical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglycerides, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet

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Relation: https://www.frontiersin.org/articles/10.3389/fnut.2021.761213/full; Diaz-Castro J, Garcia-Vega JE, Ochoa JJ, Puche-Juarez M, Toledano JM, Moreno-Fernandez J. Implementation of a Physical Activity Program Protocol in Schoolchildren: Effects on the Endocrine Adipose Tissue and Cognitive Functions. Front Nutr. 2021 Oct 22;8:761213; http://hdl.handle.net/10668/4173; PMC8568884

Availability: http://hdl.handle.net/10668/4173
https://doi.org/10.3389/fnut.2021.761213

Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin Resistance

Authors: Castellano-Castillo, Daniel, Ramos-Molina, Bruno, Oliva-Olivera, Wilfredo, Ocaña-Wilhelmi, Luis, Queipo-Ortuño, María Isabel, Cardona, Fernando

Contributors: Castellano-Castillo,D, Oliva-Olivera,W Instituto de Investigación Biomédica de Málaga, Universidad de Málaga, Málaga, Spain. Ramos-Molina,B Grupo de Obesidad y Metabolismo, Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), Murcia, Spain. Ocaña-Wilhelmi,L Unidad de Cirugía Metabólica, Hospital Clínico Virgen de la Victoria, Málaga, Spain. Queipo-Ortuño,MI Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga (IBIMA)-CIMES-UMA, Málaga, Spain. Cardona,F UGC Pediatría, Instituto de Investigación Biomédica de Málaga, Hospital Regional de Málaga, Málaga, Spain. Cardona,F Department of Surgical Specialties, Biochemistry and Immunology School of Medicine, University of Malaga, Málaga, Spain., This study was supported by research grants from the Institute of Health Carlos III (ISCIII) (PI18/00453, PI17/01104) and co-financed by the European Regional Development Fund (ERDF). BRM was supported by the “Miguel Servet Type I” program (CP19/00098) from the ISCIII. FC was supported by the “Nicolas Monardes” program from the Andalusian Health Public System (C-0032-2016). MQO was supported by the “Miguel Servet Type II” program (CPII18/00003) from the ISCIII and by the “Nicolas Monardes” program from the Andalusian Health Public System (C-0030-2018).

Subject Terms: Epigenetics, H3k4me3, Adipose tissue, Obesity, Insulin resistance, Epigenómica, Código de histonas, Tejido adiposo, Obesidad, Resistencia a la insulina, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Amino Acid Sequence::Histone Code, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Chromatin Immunoprecipitation, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Extracellular Space::Extracellular Matrix, Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics::Epigenomics

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Relation: https://www.mdpi.com/2227-9059/9/10/1363; Castellano-Castillo D, Ramos-Molina B, Oliva-Olivera W, Ocaña-Wilhelmi L, Queipo-Ortuño MI, Cardona F. Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin Resistance. Biomedicines. 2021 Sep 30;9(10):1363; http://hdl.handle.net/10668/4512; PMC8533428

Availability: http://hdl.handle.net/10668/4512
https://doi.org/10.3390/biomedicines9101363

Adiposity Is Related to Inflammatory Disease Activity in Juvenile Idiopathic Arthritis

Authors: Diaz-Cordovés Rego, Gisela, Núñez-Cuadros, Esmeralda, Mena-Vázquez, Natalia, Aguado Henche, Soledad, Galindo-Zavala, Rocío, Manrique-Arija, Sara, Martín-Pedraz, Laura, Redondo-Rodríguez, Rocio, Godoy-Navarrete, Francisco Javier, Fernández-Nebro, Antonio

Contributors: Diaz-Cordovés Rego,G, Mena-Vázquez,N, Manrique-Arija,S, Redondo-Rodríguez,R, Godoy-Navarrete,FJ, Fernández-Nebro,A Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain. Diaz-Cordovés Rego,G, Fernández-Nebro,A UGC de Reumatología, Hospital Regional Universitario de Málaga, Málaga, Spain. Núñez-Cuadros,E, Galindo-Zavala,R, Martín-Pedraz,L UGC de Pediatría, Hospital Regional Universitario de Málaga, Málaga, Spain. Aguado Henche,S Departamento de Anatomía y Embriología Humana, Facultad de Medicina, Universidad de Alcalá de Henares, Madrid, Spain. Fernández-Nebro,A Departamento de Medicina, Universidad de Málaga, Málaga, Spain., This research was funded by a grant for medical researchers of the “Sociedad Española de Reumatología Pediatrica”

Subject Terms: Juvenile idiopathic arthritis, Adiposity, Inflammatory disease activity, Body mass index, Dual-energy x-ray absorptiometry, Overweight, Obesity, Body composition, Artritis juvenil, Adiposidad, Índice de masa corporal, Absorciometría de fotón, Sobrepeso, Obesidad, Composición corporal, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Radiography::Absorptiometry, Photon, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Fat Distribution::Adiposity, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies, Medical Subject Headings::Diseases::Musculoskeletal Diseases::Joint Diseases::Arthritis::Arthritis, Juvenile, Medical Subject Headings::Anatomy::Body Regions::Extremities::Lower Extremity::Leg, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Body Composition, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue

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Relation: https://www.mdpi.com/2077-0383/10/17/3949/htm; Diaz-Cordovés Rego G, Núñez-Cuadros E, Mena-Vázquez N, Aguado Henche S, Galindo-Zavala R, Manrique-Arija S, et al. Adiposity Is Related to Inflammatory Disease Activity in Juvenile Idiopathic Arthritis. J Clin Med. 2021 Aug 31;10(17):3949; http://hdl.handle.net/10668/4274; PMC8432058

Availability: http://hdl.handle.net/10668/4274
https://doi.org/10.3390/jcm10173949

In Patients With Obesity, the Number of Adipose Tissue Mast Cells Is Significantly Lower in Subjects With Type 2 Diabetes

Authors: David Lopez-Perez, Anaïs Redruello-Romero, Jesús Garcia-Rubio, Carlos Arana, Luis A. Garcia-Escudero, Francisco Tamayo, Jose D. Puentes-Pardo, Sara Moreno-SanJuan, Javier Salmeron, Armando Blanco, Julio Galvez, Josefa Leon, Ángel Carazo

Contributors: [Lopez-Perez,D, Puentes-Pardo,JD, Galvez,J] Department of Pharmacology, Faculty of Pharmacy, University of Granada, Granada, Spain. [Lopez-Perez,D, Redruello-Romero,A, Galvez,J, Leon,J, Carazo,A] Research Unit, Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain. [Garcia-Rubio,J, Tamayo,F] Surgery Unit, San Cecilio University Hospital, Granada, Spain. [Arana,C] Endocrinology and Nutrition Unit, Virgen de las Nieves University Hospital, Granada, Spain. [García-Escuder,LA] Department of Statistics and Operative Research, Faculty of Sciences, University of Valladolid, Valladolid, Spain. [Moreno-SanJuan,S] Cytometry and Microscopy Research Service, Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain. [Salmeron,J] Gastroenterology Unit, San Cecilio University Hospital, Granada, Spain. [Blanco,A] Department of Computer Science and Artificial Intelligence, University of Granada, Granada, Spain. [Galvez,J] Centro de Investigación Biomédica En Red para Enfermedades Hepáticas y Digestivas (CIBER-EHD), Center for Biomedical Research, University of Granada, Granada, Spain. [Leon,J, Carazo,A] Clinical Management Unit of Digestive Disease, San Cecilio University Hospital, Granada, Spain., Instituto de Salud Carlos III (grant PI18/01947). Instituto de Salud Carlos III is a research institution from the Spanish government that funds biomedical research. Instituto de Salud Carlos III funded all the experiments.

Source: Front Immunol
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Universidad de Granada (UGR)
Digibug: Repositorio Institucional de la Universidad de Granada
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
Frontiers in Immunology, Vol 12 (2021)

Subject Terms: 0301 basic medicine, obesity, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers, Medical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestinal Mucosa, Adipose Tissue, White, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2, Immunology, Adipose tissue, Neovascularization, Physiologic, Cell Count, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Mast Cells, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Mast cell, Immunophenotyping, angiogenesis, 03 medical and health sciences, Humans, T2D, Flow cytometry, Mast Cells, Obesity, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Intestinal Mucosa, 10. No inequality, Inflammation, 2. Zero hunger, 0303 health sciences, Adipogenesis, flow cytometry, Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Neovascularization, Physiologic, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Adipogenesis, RC581-607, adipose tissue, 3. Good health, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Immunologic Tests::Immunophenotyping, Adipose Tissue, Diabetes Mellitus, Type 2, Angiogenesis, Immunologic diseases. Allergy, mast cell, Biomarkers

File Description: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Access URL: https://pubmed.ncbi.nlm.nih.gov/34093556
http://hdl.handle.net/10668/3523
https://doaj.org/article/8213980e590e43e2ba2c4b49b47d88f1
https://www.frontiersin.org/articles/10.3389/fimmu.2021.664576/full
https://digibug.ugr.es/handle/10481/69363
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177010
https://www.ncbi.nlm.nih.gov/pubmed/34093556
https://pubmed.ncbi.nlm.nih.gov/34093556/
https://europepmc.org/articles/PMC8177010/figure/f3/
http://hdl.handle.net/10481/69363
https://hdl.handle.net/10668/3523

DNA Methylation in infants with low and high body fatness

Authors: Henriksson, Pontus, Lentini, Antonio, Altmäe, Signe, Brodin, David, Müller, Patrick, Forsum, Elisabet, Nestor, Colm E., Löf, Marie

Contributors: Henriksson,P, Löf,M Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden. Lentini,A, Nestor,CE Crown Princess Victoria Children’s Hospital, and Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden. Altmäe,S Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of Granada, Granada, Spain. Altmäe,S Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain. Brodin,D, Müller,P, Löf,M Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden. Forsum,E Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden., The study was funded by Formas (data collection) and a grant from Bo and Vera Ax:son Johnsons Foundation (data analysis) (both ML). CEN was supported by grants from the Swedish Research Council (2015–03495) and the Swedish Cancer Society (CAN 2017/625). SA was supported by grants from the Spanish Ministry of Economy, Industry and Competitiveness (MINECO) and European Regional Development Fund (FEDER) grants: RYC-2016-21199 and ENDORE SAF2017–87526. The funding body had no role in the design of the study, data collection, analysis and interpretation of data, writing of the manuscript and the decision to publish. Open Access funding provided by Linköping University Library.

Subject Terms: DNA Methylation, Birth weight, Body composition, Body mass index, Obesity, Epigenetic, Metilación de ADN, Peso al nacer, Composición corporal, Índice de masa corporal, Obesidad, Epigenómica, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Birth Weight, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Body Composition, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Persons::Persons::Age Groups::Infant, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation, Medical Subject Headings::Anatomy::Tissues::Membranes::Mucous Membrane::Mouth Mucosa, Medical Subject Headings::Persons::Persons::Parents, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Plethysmography, Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Embryonic and Fetal Development::Fetal Development, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic

File Description: application/pdf

Relation: https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-020-07169-7; Henriksson P, Lentini A, Altmäe S, Brodin D, Müller P, Forsum E, et al. DNA methylation in infants with low and high body fatness. BMC Genomics. 2020 Nov 9;21(1):769; http://hdl.handle.net/10668/4146; PMC7654595

Availability: http://hdl.handle.net/10668/4146
https://doi.org/10.1186/s12864-020-07169-7

The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease

Authors: Romero-Zerbo, Silvana Y., García-Fernández, María, Espinosa-Jiménez, Vanesa, Pozo-Morales, Macarena, Escamilla-Sánchez, Alejandro, Sánchez-Salido, Lourdes, Lara, Estrella, Cobo-Vuilleumier, Nadia, Rafacho, Alex, Olveira, Gabriel, Rojo-Martínez, Gemma, Gauthier, Benoit R., González-Mariscal, Isabel, Bermúdez-Silva, Francisco J.

Contributors: Romero-Zerbo,SY, Espinosa-Jiménez,V, Pozo-Morales,M, Sánchez-Salido,L, Olveira,G, Rojo-Martínez,G, González-Mariscal,I, Bermúdez-Silva, FJ UGC Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga-IBIMA, Hospital Regional de Málaga, Universidad de Málaga, Málaga, Spain. García-Fernández,M, Lara,E, Departamento de Fisiología Humana, Facultad de Medicina, Instituto de Investigación Biomédica de Málaga-IBIMA, Universidad de Málaga, Málaga, Spain. Escamilla-Sánchez,A Plataforma de Microscopía, Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. Cobo-Vuilleumier,N, Gauthier,BR Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), Seville, Spain. Rafacho,A Laboratory of Investigation in Chronic Diseases - LIDoC, Department of Physiological Sciences, Center of Biological Sciences, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil. Olveira,G, Gauthier,BR, Bermúdez-Silva,FJ Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., This work was supported by Consejería de Salud de la Junta de Andalucía Andalucía se mueve con Europa (PI-0574-2012 to SR-Z) and Instituto de Salud Carlos III (ISCIII), Ministerio de Sanidad, Gobierno de España Una manera de hacer Europa (13/00309 and 17/01004 to FB-S, co-funded by FEDER, EU). SR-Z was recipient of a postdoctoral fellowship from Consejeria de Salud de la Junta de Andalucia (RH-0070-2013). AR received a short-term stay fellowship from Banco Santander (Programa Bolsas Iberoamericanas Jovens Professores e Pesquisadores) and was funded by a CNPq research grant (Grant No. 306359/2017-0). IG-M was funded by the European Commission Research & Innovation, Horizon2020 program, call H2020-MSCA-IF-2016 (GA: 748749). FB-S belongs to the regional Nicolás Monardes research program of the Consejería de Salud (C-0070-2012 and RC0005-2016, Junta de Andalucía, Spain). BG was supported by the Ministerio de Economia y Competitividad co-funded by FEDER (PI10/00871, PI13/00593 and BFU2017-83588-P). CIBERDEM is an initiative of the Instituto de Salud Carlos III.

Subject Terms: Cannabinoids, Inflammation, Prediabetes, NAFLD, Obesity, Liver, Islets of langerhans, Adipose tissue, Cannabinoides, Inflamación, Enfermedad del hígado graso no alcohólico, Obesidad, Hígado, Islotes pancreáticos, Tejido adiposo, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Pharmacological Processes::Cytoprotection, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, High-Fat, Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation, Medical Subject Headings::Anatomy::Digestive System::Liver, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Laboratory::Animals, Inbred Strains::Mice

File Description: application/pdf

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2020.00103/full; Romero-Zerbo SY, García-Fernández M, Espinosa-Jiménez V, Pozo-Morales M, Escamilla-Sánchez A, Sánchez-Salido L, et al. The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease. Front Endocrinol. 2020 Mar 6;11:103; http://hdl.handle.net/10668/3582; PMC7067697

Availability: http://hdl.handle.net/10668/3582
https://doi.org/10.3389/fendo.2020.00103

NQO1 protects obese mice through improvements in glucose and lipid metabolism

Authors: Di Francesco, Andrea, Choi, Youngshim, Bernier, Michel, Zhang, Yingchun, Diaz-Ruiz, Alberto, Aon, Miguel A., Kalafut, Krystle, Ehrlich, Margaux R., Murt, Kelsey, Ali, Ahmed, Pearson, Kevin J., Levan, Sophie, Preston, Joshua D., Martin-Montalvo, Alejandro, Martindale, Jennifer L., Abdelmohsen, Kotb, Michel, Cole R., Willmes, Diana M., Henke, Christine, Navas, Placido, Villalba, Jose Manuel, Siegel, David, Gorospe, Myriam, Fritz, Kristofer, Biswal, Shyam, Ross, David, de Cabo, Rafael

Contributors: Di Francesco,A, Bernier,M, Zhang,Y, Diaz-Ruiz,A, Aon,MA, Kalafut,K, Ehrlich,MR, Murt,K, Ali,A, Pearson,KJ, Levan,S, Martin-Montalvo,A, de Cabo,R Translational Gerontology Branch, National Institute on Aging Intramural Program, National Institutes of Health, Baltimore, MD, USA. Choi,Y, Biswal,S Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Diaz-Ruiz,A Nutritional Interventions Group, Precision Nutrition and Aging, Institute IMDEA Food, Madrid, Spain. Pearson,KJ, Preston,JD Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, KY, USA. Martindale,JL, Abdelmohsen,K, Gorospe,M Laboratory of Genetics and Genomics, National Institute on Aging Intramural Program, National Institutes of Health, Baltimore, MD, USA. Michel,CR, Siegel,D, Fritz,K, Ross,D Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Willmes,DM, Henke,C Molecular Diabetology, Paul Langerhans Institute Dresden of the Helmholtz German Center for Diabetes Research Munich, University Hospital Carl Gustav Carus and Faculty of Medicine, TU Dresden, Dresden, Germany. Navas,P Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC-JA,Sevilla, Spain. Villalba,JM Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Campus de Excelencia Internacional Agroalimentario, ceiA3, Sevilla, Spain. Di Francesco,A Present address: Calico Life Sciences, South San Francisco, CA, USA. Choi,Y Present address: University of Maryland School of Medicine, Baltimore, MD, USA. Zhang,Y Present address: College of Pharmaceutical Sciences and Chinese Medicine, Southwest University, Chongqing, People’s Republic of China. Kalafut,K Present address: Harvard T.H. Chan School of Public Health, Boston, MA, USA. Ehrlich,MR Present address: Department Food Science, Cornell University, Ithaca, NY, USA. Murt,K Present address: Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Ali,A Present address: Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. Preston,JD Present address: Emory University School of Medicine (MD/PhD program), Atlanta, GA, USA. Martin-Montalvo,A Present address: Department of Regeneration and Cell Therapy, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.

Subject Terms: Insulin resistance, Mice, Metabolism, NF-E2-related factor 2, RNA, Glucose, Resistencia a la insulina, Ratones, Metabolismo, Factor 2 relacionado con NF-E2, ARN, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::Basic-Leucine Zipper Transcription Factors::NF-E2-Related Factor 2, Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, High-Fat, and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Sirtuins::Sirtuin 3, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Acylation::Acetylation, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Anatomy::Tissues::Muscles::Muscle, Striated::Muscle, Skeletal, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Energy Metabolism::Oxidation-Reduction, Medical Subject Headings::Analytical

File Description: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Relation: https://www.nature.com/articles/s41514-020-00051-6; Di Francesco A, Choi Y, Bernier M, Zhang Y, Diaz-Ruiz A, Aon MA, et al. NQO1 protects obese mice through improvements in glucose and lipid metabolism. NPJ Aging Mech Dis. 2020 Nov 19;6(1):13; http://hdl.handle.net/10668/3814

Availability: http://hdl.handle.net/10668/3814
https://doi.org/10.1038/s41514-020-00051-6

Canine colostrum exosomes: characterization and influence on the canine mesenchymal stem cell secretory profile and fibroblast anti-oxidative capacity

Authors: Villatoro, Antonio J., Martín-Astorga, María del Carmen, Alcoholado, Cristina, Becerra, José

Contributors: Villatoro,AJ, Martín-Astorga,MC, Alcoholado,C, Becerra,J Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain. Villatoro,AJ Instituto de Immunología Clínica y Terapia Celular (IMMUNESTEM), Málaga, Spain. Alcoholado,C, Becerra,J Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain. Becerra,J Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain., This work was partially supported by the Spanish Network on Cell Therapy (Red TerCel, RD16/0011/0022), Junta de Andalucía and University of Málaga. CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008–2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund.

Subject Terms: Canine colostrum milk, Mesenchymal stem cells, Exosomes, Dog, Anti-oxidative capacity, Calostro, Perros, Células madre mesenquimatosas, Exosomas, Antioxidantes, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Protective Agents::Antioxidants, Medical Subject Headings::Anatomy::Cells::Bone Marrow Cells, Medical Subject Headings::Anatomy::Cells::Cells, Cultured, Medical Subject Headings::Anatomy::Fluids and Secretions::Bodily Secretions::Colostrum, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Carnivora::Canidae::Dogs, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Transport Vesicles::Exosomes, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Proteome

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Relation: https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-020-02623-w; Villatoro AJ, Martín-Astorga MDC, Alcoholado C, Becerra J. Canine colostrum exosomes: characterization and influence on the canine mesenchymal stem cell secretory profile and fibroblast anti-oxidative capacity. BMC Vet Res. 2020 Nov 2;16(1):417; http://hdl.handle.net/10668/3600; PMC7607682

Availability: http://hdl.handle.net/10668/3600
https://doi.org/10.1186/s12917-020-02623-w

Sedentary Time Accumulated in Bouts is Positively Associated with Disease Severity in Fibromyalgia: The Al-Ándalus Project

Authors: Segura-Jiménez, Víctor, Gavilán-Carrera, Blanca, Acosta-Manzano, Pedro, Cook, Dane B., Estévez-López, Fernando, Delgado-Fernández, Manuel

Contributors: Segura-Jiménez,V Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Cádiz, Spain. Segura-Jiménez,V Biomedical Research and Innovation Institute of Cádiz (INiBICA) Research Unit, Puerta del Mar University Hospital University of Cádiz, Cádiz, Spain. Gavilán-Carrera,B, Acosta-Manzano,P, Delgado-Fernández,M Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain. Gavilán-Carrera,B, Delgado-Fernández,M Sport and Health University Research Institute, University of Granada, Granada, Spain. Cook,DB Department of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA. Estévez-López,F Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., This research was funded by the Spanish Ministry of Science and Innovation (I+D+I DEP2010-15639), the Consejeria de Turismo, Comercio y Deporte (CTCD-201000019242-TRA), the Spanish Ministry of Education (FPU15/00002), Granada Research of Excelence Initiative on Biohealth (GREIB), Campus BioTic, University of Granada, Spain, the University of Granada (Plan Propio de Investigación 2016, Excellence actions: Units of Excellence, Unit of Excellence on Exercise and Health UCEES ), and the University of Cádiz (Research and Transfer Activity Promotion Program). FE-L has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 707404.

Subject Terms: Device-measured sedentary behaviour, Sedentary breaks, Sedentary patterns, Fibromyalgia severity, Physical activity, Fibromialgia, Ejercicio físico, Andalucía, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Diseases::Nervous System Diseases::Neuromuscular Diseases::Muscular Diseases::Fibromyalgia, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence Intervals, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electricity::Electric Conductivity::Electric Impedance, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Accelerometry, Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activity::Exercise, Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Physical Fitness, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Health Status Indicators::Patient Acuity::Severity of Illness Index, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain

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Relation: https://www.mdpi.com/2077-0383/9/3/733/htm; Segura-Jiménez V, Gavilán-Carrera B, Acosta-Manzano P, Cook DB, Estévez-López F, Delgado-Fernández M. Sedentary Time Accumulated in Bouts is Positively Associated with Disease Severity in Fibromyalgia: The Al-Ándalus Project. J Clin Med. 2020 Mar 9;9(3):733; http://hdl.handle.net/10668/3962; PMC7141225

Availability: http://hdl.handle.net/10668/3962
https://doi.org/10.3390/jcm9030733

Overexpression of scavenger receptor and infiltration of macrophage in epicardial adipose tissue of patients with ischemic heart disease and diabetes

Authors: Santiago-Fernández, Concepción, Pérez-Belmonte, Luis M., Millán-Gómez, Mercedes, Moreno-Santos, Inmaculada, Carrasco-Chinchilla, Fernando, Ruiz-Salas, Amalio, Morcillo-Hidalgo, Luis, Melero, José M., Garrido-Sánchez, Lourdes, Jiménez-Navarro, Manuel

Contributors: Santiago-Fernández,C, Garrido-Sánchez,L Department of Endocrinology and Nutrition, Virgen de la Victoria Hospital (IBIMA), Malaga University, Malaga, Spain. Santiago-Fernández,C, Garrido-Sánchez,L Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Malaga, Spain. Pérez-Belmonte,LM, Millán-Gómez,M, Moreno-Santos,I, Carrasco-Chinchilla,F, Ruiz-Salas,A, Morcillo-Hidalgo,L, Melero,JM, Jiménez-Navarro,M Unidad de Gestión Clínica Área del Corazón, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Universidad de Málaga (UMA), Malaga, Spain. Pérez-Belmonte,LM, Jiménez-Navarro,M Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Malaga, Spain., This work was supported by Grants from the Spanish Ministry of Health (FIS) (PI13/02542, PI11/01661) and Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV) (CB16/11/00360), Instituto de Salud Carlos III co-funded by the Fondo Europeo de Desarrollo Regional (FEDER).

Subject Terms: Scavenger receptors, Oxidized low-density, Epicardial adipose tissue, Diabetes mellitus, Ischemic heart disease, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement, Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Coronary Disease::Coronary Artery Disease, Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2, Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Cardiomyopathies::Diabetic Cardiomyopathies, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins, LDL, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Macrophages, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia, Medical Subject Headings::Anatomy::Cardiovascular System::Heart::Pericardium, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Scavenger, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Up-Regulation

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Relation: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-1842-2; Santiago-Fernández C, Pérez-Belmonte LM, Millán-Gómez M, Moreno-Santos I, Carrasco-Chinchilla F, Ruiz-Salas A, et al. Overexpression of scavenger receptor and infiltration of macrophage in epicardial adipose tissue of patients with ischemic heart disease and diabetes. J Transl Med. 2019 Mar 20;17(1):95.; http://hdl.handle.net/10668/3191; PMC6425581

Availability: http://hdl.handle.net/10668/3191
https://doi.org/10.1186/s12967-019-1842-2

Adipose tissue concentrations of persistent organic pollutants and total cancer risk in an adult cohort from Southern Spain: Preliminary data from year 9 of the follow-up

Authors: Arrebola, Juan P, Fernández, Mariana F, Martín-Olmedo, Piedad, Molina-Molina, José Manuel, Sánchez-Pérez, María J, Sánchez-Cantalejo, Emilio, Molina-Portillo, Elena, Expósito, José, Bonde, Jens Peter, Olea, Nicolás

Contributors: [Arrebola, JP, Expósito, J] Oncology Unit. Virgen de las Nieves University Hospital, Granada, Spain. [Fernández, MF, Olea, N] Instituto de Investigación Biosanitaria ibs.Granada, University of Granada, San Cecilio University Hospital. Granada, Spain.[Martín-Olmedo, P, Sánchez-Pérez, MJ, Sánchez-Cantalejo, E, Molina-Portillo, E] Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria de Granada, Granada, Spain. [Bonde, JP] Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, University of Copenhagen, Denmark, This study was supported in part by research grants from the Spanish Ministry of Health (FIS 02/974, EUS2008-03574), CIBER de Epidemiología, Junta de Andalucía (01/264, P09-CTS-5488 Project of Excellence, PI-0675-2010,and PI-0513-2012), and the Instituto de Salud Carlos III (FIS PI11/0610).

Source: Digibug. Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
instname
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía

Subject Terms: Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Follow-Up Studies, Adult, Male, Hazard ratio, Medical Subject Headings::Diseases::Neoplasms, Adipose tissue, Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain, 01 natural sciences, 7. Clean energy, Hazardous Substances, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Statistics as Topic::Regression Analysis, 03 medical and health sciences, 0302 clinical medicine, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult, Neoplasms, Humans, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Prospective study, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure, Cancer, 0105 earth and related environmental sciences, Follow-up, Persistent organic pollutants, Environmental Exposure, Middle Aged, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Hazardous Substances, 3. Good health, Medical Subject Headings::Check Tags::Male, Adipose Tissue, Spain, 13. Climate action, Regression Analysis, Environmental Pollutants, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants, Follow-Up Studies

File Description: application/pdf

Access URL: https://digibug.ugr.es/bitstream/10481/34557/2/Arrebola_Tables1-3_Figure4.pdf
https://pubmed.ncbi.nlm.nih.gov/25217999
http://hdl.handle.net/10668/1993
https://www.repositoriosalud.es/handle/10668/1993
http://ui.adsabs.harvard.edu/abs/2014ScTEn.500..243A/abstract
https://core.ac.uk/display/43490023
https://www.sciencedirect.com/science/article/pii/S0048969714012224
http://www.repositoriosalud.es/bitstream/10668/1993/1/Arrebola_AdiposeTissueConcentrations.pdf
https://europepmc.org/abstract/MED/25217999
http://hdl.handle.net/10481/34557

Disruption of GIP/GIPR Axis in Human Adipose Tissue Is Linked to Obesity and Insulin Resistance

Authors: Ceperuelo-Mallafré, Victoria, Durán, Xavier, Pachón, Gisela, Roche, Kelly, Garrido-Sánchez, Lourdes, Vilarrasa, Nuria, Tinahones, Francisco J, Vicente, Vicente, Pujol, Jordi, Vendrell, Joan, Fernández-Veledo, Sonia

Contributors: [Ceperuelo-Mallafré,V, Garrido-Sánchez,L, Tinahones,FJ] CIBERobn Instituto de Salud Carlos III, CIBER Fisiopatología de la Obesidad y de la Nutrición, Madrid, Spain. [Ceperuelo-Mallafré,V, Tinahones,FJ] Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Durán,X, Pachón,G, Roche,K, Vilarrasa,N, Vendrell,J, Fernández-Veledo, Sonia] CIBERDEM Instituto de Salud Carlos III, CIBER Diabetes y Enfermedades Metabólicas Asociadas, Madrid, Spain. [Pachón,G, Vicente,V, Fernández-Veledo,S] Hospital Universitario de Tarragona Joan XXIII, Instituto de Investigación Sanitaria Pere Virgili, Universitat Rovira Virgili, Tarragona, Spain. [Vilarrasa,N, Pujol,Jordi] Hospital Universitario de Bellvitge, Barcelona, Spain., Thisworkwas supported by grants from the Spanish Ministry of Economy and Competitiveness ( SAF2012-36186 and CP10/ 00438 to S.F.-V., PI11/0085 to J.V., and PI12/02355 to F.J.T.). S.F.-V. acknowledges support from the 'Miguel Servet' tenure track program (CP10/00438) from the Fondo de Investigación Sanitaria and cofinanced by the European Regional Development Fund. V.C.-M. is supported by an FPI fellowship from the Spanish Ministry.

Source: RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname

Subject Terms: Adult, Male, 0301 basic medicine, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Peptide::Receptors, Gastrointestinal Hormone, Down-Regulation, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Waist Circumference, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Gastric Inhibitory Polypeptide, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Body Mass Index, Cell Line, Receptors, Gastrointestinal Hormone, Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Gastrointestinal Hormones::Gastric Inhibitory Polypeptide, 03 medical and health sciences, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Biometry::Anthropometry::Body Mass Index, Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult, Adipocytes, Humans, Obesity, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Aged, 2. Zero hunger, 0303 health sciences, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction, Middle Aged, 3. Good health, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance, Adipose Tissue, Female, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation, Insulin Resistance, Waist Circumference, Signal Transduction

File Description: application/pdf

Access URL: https://academic.oup.com/jcem/article-pdf/99/5/E908/9050790/jcemE908.pdf
https://pubmed.ncbi.nlm.nih.gov/24512489
http://hdl.handle.net/10668/2050
https://www.ncbi.nlm.nih.gov/pubmed/24512489
https://europepmc.org/article/MED/24512489
https://pubmed.ncbi.nlm.nih.gov/24512489/
https://www.repositoriosalud.es/bitstream/10668/2050/1/Ceperuelo_Disruption.pdf
https://academic.oup.com/jcem/article/99/5/E908/2538029
https://www.repositoriosalud.es/handle/10668/2050
https://hdl.handle.net/10668/2050

Adipose Mesenchymal Stromal Cells Isolated From Type 2 Diabetic Patients Display Reduced Fibrinolytic Activity

Authors: Acosta, Lourdes, Hmadcha, Abdelkrim, Escacena, Natalia, Pérez-Camacho, Inmaculada, de la Cuesta, Antonio, Ruiz-Salmeron, Rafael, Gauthier, Benoit R, Soria, Bernat

Contributors: [Acosta,L, Hmadcha,A, Escacena,N, Gauthier,BR, Soria,B] Centro Andaluz de Biología Molecular y Medicina Regenerativa, Sevilla, Spain. [Hmadcha,A, Soria,B] CIBER de Diabetes y Enfermedades Metabolicas Asociadas, Barcelona, Spain. [Pérez-Camacho, I, de la Cuesta,A, Ruiz-Salmeron,R] Hospitales Universitarios San Lázaro and Virgen Macarena, Sevilla, Spain, The authors are supported by the Fundación Progreso y Salud, Consejería de Salud, Junta de Andalucía (Grant PI-0022/2008) and Consejería de Innovación Ciencia y Empresa, Junta de Andalucía (Grant CTS-6505, INP-2011-1615-900000). Fondo Europeo de Desarrollo Regional (FEDER) cofunded grants from Instituto de Salud Carlos III (Red TerCel-Grant RD06/0010/0025, PI10/00964, and PI10/00871) and the Ministry of Health and Consumer Affairs (Advanced Therapies Program Grant TRA-120)., Fundación Progreso y Salud, Junta de Andalucía, European Commission, Instituto de Salud Carlos III, Red de Terapia Celular (España), Ministerio de Sanidad y Consumo (España), Fundación de la Sociedad Española de Diabetes, Fundación Andaluza de Investigación y Desarrollo, Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]

Source: Diabetes
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)

Subject Terms: Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2, Adult, Male, 0301 basic medicine, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged::Aged, 80 and over, Adolescent, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Blood Coagulation Factors::Plasminogen Inactivators::Plasminogen Activator Inhibitor 1, 03 medical and health sciences, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult, Plasminogen Activator Inhibitor 1, Humans, Medical Subject Headings::Chemicals and Drugs::Biological Factors::Blood Coagulation Factors::Tissue Plasminogen Activator, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged, Original Research, Aged, Aged, 80 and over, 0303 health sciences, Fibrinolysis, Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Blood Physiological Phenomena::Blood Physiological Processes::Hemostasis::Blood Coagulation::Fibrinolysis, Medical Subject Headings::Check Tags::Female, Mesenchymal Stem Cells, Middle Aged, 3. Good health, Medical Subject Headings::Check Tags::Male, Adipose Tissue, Diabetes Mellitus, Type 2, Tissue Plasminogen Activator, Female, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Stromal Cells::Mesenchymal Stromal Cells

File Description: application/pdf

Access URL: https://diabetes.diabetesjournals.org/content/diabetes/62/12/4266.full.pdf
https://pubmed.ncbi.nlm.nih.gov/24043757
http://hdl.handle.net/10668/2263
http://hdl.handle.net/10261/122578
https://diabetes.diabetesjournals.org/content/62/12/4266.full.pdf+html
https://pubmed.ncbi.nlm.nih.gov/24043757
https://www.repositoriosalud.es/bitstream/10668/2263/1/Acosta_MesenchymalStromalCells.pdf
http://digital.csic.es/handle/10261/122578
http://europepmc.org/articles/PMC3837061
https://paperity.org/p/45322939/adipose-mesenchymal-stromal-cells-isolated-from-type-2-diabetic-patients-display-reduced
https://hdl.handle.net/10668/2263

Comparison of body mass index (BMI) with the CUN-BAE body adiposity estimator in the prediction of hypertension and type 2 diabetes

Authors: Martín, Vicente, Dávila-Batista, Verónica, Castilla, Jesús, Godoy, Pere, Delgado-Rodríguez, Miguel, Soldevila, Nuria, Molina, Antonio J., Fernandez-Villa, Tania, Astray, Jenaro, Castro, Ady, González-Candelas, Fernando, Mayoral, José María, Quintana, José María, Domínguez, Angela

Contributors: CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain, Martín,V, Dávila-Batista,V, Molina,AJ, Fernandez-Villa,T Grupo de Investigación Interacciones Gen-Ambiente y Salud - Universidad de León (Gigas), León, Spain. Martín,V, Castilla,J, Godoy,P, Delgado-Rodríguez,M, Soldevila,N, González-Candelas,F, Quintana,JM, Domínguez,A CIBER Epidemiología y Salud Pública, Madrid, Spain. Castilla,J Instituto de Salud Pública de Navarra, Pamplona, Spain. Godoy,P Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. Delgado-Rodríguez,M División de Medicina Preventiva y Salud Pública, Universidad de Jaén, Jaén, Spain. Astray,J Subdirección de Vigilancia. Comunidad de Madrid, Madrid, Spain. Castro,A CIBER Enfermedades Respiratorias, Madrid, Spain. González-Candelas,F Unidad Mixta Genómica y Salud CSISP (FISABIO)-Universitat de València, Valencia, Spain. Mayoral, JM Servicio de Vigilancia de Andalucía, Sevilla, Spain. Quintana,JM Fundación Vasca de Innovación e Investigación Sanitarias, Sondika, Spain. Domínguez,A Departament de Salut Pública, Universitat de Barcelona, Barcelona, Spain. Dávila-Batista,V Facultad de Ciencias de la Salud. Campus de Vegazana. Universidad de León, León, Spain.

Subject Terms: Obesity, Body mass index, Body fat, CUN-BAE, Population attributable fraction, Hypertension, Diabetes, Obesidad, Índice de masa corporal, Hipertensión, Medical Subject Headings::Persons::Persons::Age Groups::Adult, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Anthropometry, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass Index, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Causality, Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies, Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight::Obesity, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Composition::Body Fat Distribution::Adiposity

File Description: application/pdf

Relation: https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-016-2728-3; Martín V, Dávila-Batista V, Castilla J, Godoy P, Delgado-Rodríguez M, Soldevila N, et al. Comparison of body mass index (BMI) with the CUN-BAE body adiposity estimator in the prediction of hypertension and type 2 diabetes. BMC Public Health. 2016 Jan 27;16:82; http://hdl.handle.net/10668/2602; PMC4730622

Availability: http://hdl.handle.net/10668/2602
https://doi.org/10.1186/s12889-016-2728-3

A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women.

Authors: Pastor, Antoni, Fernández-Aranda, Fernando, Fitó, Montserrat, Jiménez-Murcia, Susana, Botella, Cristina, Fernández-Real, José M, Frühbeck, Gema, Tinahones, Francisco J, Fagundo, Ana B, Rodríguez, Joan, Agüera, Zaida, Langohr, Klaus, Casanueva, Felipe F, Torre, Rafael de la

Contributors: Pastor,A, Rodríguez,J, Langohr,K, Torre,R de la Integrative Pharmacology and Systems Neuroscience Research Group, Neuroscience Research Program, IMIM (Hospital de Mar Medical Research Institute), Barcelona, Spain. Pastor,A Department of Pharmacology, School of Medicine, Universitat Autònoma de Barcelona, Spain. Pastor,A, Fernández-Aranda,F, Fitó,M, Jiménez-Murcia,S, Botella,C, Fernández-Real,JM, Frühbeck,G, Tinahones,FJ, Casanueva,FF, Torre,R de la CIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Madrid, Spain. Fernández-Aranda,F, Fagundo,AB, Agüera,Z Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain. Fitó,M Cardiovascular Risk and Nutrition Research Group, Inflammatory and Cardiovascular Disorders Research Program, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. Jiménez-Murcia,S Department of Clinical Sciences, School of Medicine, University of Barcelona, Barcelona, Spain. Botella,C Department of Basic Psychology, Clinic and Psychobiology, University Jaume I, Castelló, Spain. Fernández-Real,JM Department of Diabetes, Endocrinology and Nutrition, Institut d’Investigació Biomèdica de Girona (IdlBGi), Hospital Dr Josep Trueta, Girona, Spain. Frühbeck,G Department of Endocrinology and Nutrition, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Pamplona, Spain. Tinahones,FJ Department of Diabetes, Endocrinology and Nutrition, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain. Langohr,K Department of Statistics and Operations Research, Universitat Politècnica de Catalunya, Barcelona, Spain. Casanueva,FF Endocrine Division, Complejo Hospitalario U. de Santiago, Santiago de Compostela University, Santiago de Compostela, Spain. Torre,R de la Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain., The work was supported by the following: Instituto Salud Carlos III, http://www.isciii.es , FIS PI11/210, FIS14/290, Centro de Investigación Biomédica en Red. Fisiopatología de la Obesidad y Nutrición (CIBEROB), http://www.ciberobn.es, and Agència de Gestió d ́Ajuts Universitaris i de Recerca (AGAUR), www.gencat.cat/agaur/ , 2014 SGR 1672.

Subject Terms: Tejido adiposo, Obesidad mórbida, Índice de masa corporal, Endocannabinoides, Ácidos araquidónicos, Anticonceptivos, Olores, Olfato, Hábito de fumar, Etanolaminas, Humanos, Gato, Femenino, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid, Medical Subject Headings::Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::Environment::Odors, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids, Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Arachidonic Acids, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Reproductive Control Agents::Contraceptive Agents, Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Habits::Smoking, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Amino Alcohols::Ethanolamines, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Check Tags::Female

File Description: application/pdf

Relation: http://journals.plos.org/plosone/article/authors?id=10.1371%2Fjournal.pone.0148734; Pastor A, Fernández-Aranda F, Fitó M, Jiménez-Murcia S, Botella C, Fernández-Real JM, et al. A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women. PLoS ONE. 2016; 11(2):e0148734; http://hdl.handle.net/10668/2171; PMC4746072

Availability: http://hdl.handle.net/10668/2171
https://doi.org/10.1371/journal.pone.0148734

Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring.

Authors: Ramírez-López, María Teresa, Arco, Raquel, Decara, Juan, Vázquez, Mariam, Blanco, Rosario Noemí, Alén, Francisco, Suárez, Juan, Gómez de Heras, Raquel, Rodríguez de Fonseca, Fernando

Contributors: Ramírez-López,MT, Blanco, RN, Gómez De Heras, R Departamento de Psicobiología, Facultad de Psicología, Universidad Complutense de Madrid, Pozuelo de Alarcón, Madrid, Spain. Arco,R, Decara,J, Vázquez,M, Alén,F, Suárez, J Rodríguez de Fonseca,F Instituto de Investigación Biomédica de Málaga IBIMA), Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain., This work was supported by the Instituto de Salud Carlos III UEDR-FEDER, Ministerio de Economía y Competitividad UE/ERDF (PI13/0226 to F.R.F., CP12/03109 to J.S. and PSI-2012-35388 to R.G.H.), Red de Trastornos Adictivos UE/ERDF (RD12/0028/0001 to F.R.F.), CIBERobn, Consejería de Economía, Innovación y Ciencia, Junta de Andalucía, UE/ERDF (PI45403, CTS-8221, CTS-433 to F.R.F.), Consejería de Salud, Junta de Andalucía (PI0232/2008, PI0029/2008 and SAS111224 to J. S. and F.R.F. M.T. Ramírez-López has been funded by a FPU predoctoral fellowship of the Spanish Ministerio de Educación, Cultura y Deporte (AP- 2009-0225), J.S. holds “Miguel Servet”research contract from the National System of Health, ISCIII (grant numbersCP12/03109).

Subject Terms: Tejido adiposo, Adiposidad, Niños Adultos, Animales, Cannabinoides, Dieta, Endocannabinoides, Metabolismo Energético, Conducta alimentaria, Femenino, Hipercolesterolemia, Hipertrigliceridemia, Hipotálamo, Lactancia, Hígado, Masculino, Metaboloma, Obesidad, Embarazo, ARN mensajero, Receptor cannabinoide CB2, Destete, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Body Composition::Body Fat Distribution::Adiposity, Medical Subject Headings::Named Groups::Persons::Adult Children, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Terpenes::Cannabinoids, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Energy Metabolism

File Description: application/pdf

Relation: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165432; Ramírez-López MT, Arco R, Decara J, Vázquez M, Blanco RN, Alén F, et al. Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring. PLoS ONE. 2016; 11(11):e0165432; http://hdl.handle.net/10668/2542; PMC5091916

Availability: http://hdl.handle.net/10668/2542
https://doi.org/10.1371/journal.pone.0165432

Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance.

Authors: Yew Tan, Chong, Virtue, Samuel, Murfitt, Steven, Robert, Lee D, Phua, Yi Hui, Dale, Martin, Griffin, Julian L, Tinahones, Francisco, Scherer, Philipp E, Vidal-Puig, Antonio

Contributors: Yew Tan,C, Virtue,S, Dale,M, Vidal-Puig,A University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, MDU MRC. Addenbrooke’s Hospital, Cambridge, UK. Murfitt,S, Robert,LD, Phua,YH, Griffin,JL University of Cambridge Department of Biochemistry, Cambridge, UK. Tinahones,FJ UGC Endocrinologia y Nutrición (IBIMA), Hospital Virgen de la Victoria. CIBER of Physiopathology, Obesity and Nutrition (CIBEROBN) Málaga, Spain. Scherer,P Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Vidal-Puig,A Wellcome Trust Sanger Institute, Hinxton, Uk. Robert,LD, Griffin,JL Medical Research Council – Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, Uk., BB/H002731/1, Biotechnology and Biological Sciences Research Council, United Kingdom, BB/H013539/1, Biotechnology and Biological Sciences Research Council, United Kingdom, MC_G0802535, Medical Research Council, United Kingdom, MC_PC_13030, Medical Research Council, United Kingdom, MC_UP_A090_1006, Medical Research Council, United Kingdom, MC_UU_12012/2, Medical Research Council, United Kingdom, RG/12/13/29853, British Heart Foundation, United Kingdom

Subject Terms: Adiponectina, Tejido adiposo, Adiposidad, Ácidos grasos, esenciales, Ácidos grasos monoinsaturados, Humanos, Gato, Grasa intra-abdominal, Obesidad, Grasa subcutánea, Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Adipokines::Adiponectin, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Body Composition::Body Fat Distribution::Adiposity, Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Carbon, Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Fatty Acids, Essential, Monounsaturated, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglycerides

File Description: application/pdf; application/msword

Relation: http://www.nature.com/articles/srep18366; Yew Tan C, Virtue S, Murfitt S, Robert LD, Phua YH, Dale M, et al. Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance. Sci Rep. 2015; 5:18366; http://hdl.handle.net/10668/2271; PMC4683622

Availability: http://hdl.handle.net/10668/2271
https://doi.org/10.1038/srep18366

Myocardial Ischemic Subject's Thymus Fat: A Novel Source of Multipotent Stromal Cells.

Authors: Oliva-Olivera, Wilfredo, Coín-Aragüez, Leticia, Salas, Julián, Lhamyani, Said, Gentile, Adriana-Mariel, Sarria García, Esteban, Hmadcha, Abdelkrim, Zayed, Hatem, Vega-Rioja, Antonio, Tinahones, Francisco J, El Bekay, Rajaa

Contributors: Oliva-Olivera,W, Coín-Aragüez,L, Tinahones,FJ, El Bekay,R CIBER Pathophysiology of obesity and nutrition CB06/03, Carlos III Health Institute, Malaga, Spain, Laboratory of Biomedical Research, Virgen de la Victoria Clinical University Hospital, Málaga, Spain. Salas,J, Sarria García,E Cardiovascular Surgery Department, University Hospital Carlos Haya, Málaga, Spain. Lhamyani,S, Gentile,AM Research Laboratory, Science School, Málaga University, Málaga, Spain. Hmadcha,A Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), Department of Stem Cells, Sevilla, Spain. Centro de Investigación Biomédica en Red-Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain. Zayed,H Biomedical Sciences Program, Health Sciences Department, College of Arts and Sciences, Qatar University, Doha, Qatar. Vega-Rioja,A Servicio Regional de Inmunología y Alergia, Hospital Universitario Virgen Macarena, Sevilla, Spain., This work was supported in part by grants from the Instituto de Salud Carlos III/FEDER, EU (PI10/01947, PI13/02628), CTS-7895 from the Consejería de Economía e Innovación, Ciencia y Empleo, Junta de Andalucía/FEDER, EU. R. El Bekay is supported by fellowships from the ISCIII/ FEDER, EU "Miguel Servet II" (CPII13/00041). AV-R is under a contract Proyectos de I+D+i para jóvenes investigadores from the Ministerio de Economía y Competitividad (SAF2014-60649-JIN) and co-funded by Fondo Europeo de Desarrollo Regional–FEDER.

Subject Terms: Tejido adiposo, Anciano, Diferenciación celular, Adipogénesis, Proliferación de la célula, Ensayo de unidades formadoras de colonias, Proteínas de unión a ácidos Ggrasos, Citometría de flujo, Expresión génica, Inmunofenotipificación, Células del estroma mesenquimatoso, Mediana edad, Isquemia miocárdica, Osteogénesis, Medicina regenerativa, Reacción en cadena de la polimerasa de transcriptasa inversa, Proteína 1 de unión a los elementos reguladores de esteroles, Grasa subcutánea, Timo, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Cytological Techniques::Colony-Forming Units Assay, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Fatty Acid-Binding Proteins, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Cytological Techniques::Cell Separation::Flow Cytometry, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression

File Description: application/pdf; application/msword

Relation: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144401; Oliva-Olivera W, Coín-Aragüez L, Salas J, Lhamyani S, Gentile AM, Sarria García E, et al. Myocardial Ischemic Subject's Thymus Fat: A Novel Source of Multipotent Stromal Cells. PLoS ONE. 2015; 10(12):e0144401; http://hdl.handle.net/10668/2403; PMC4675557

Availability: http://hdl.handle.net/10668/2403
https://doi.org/10.1371/journal.pone.0144401