Evaluation of Marine Agarose Biomaterials for Tissue Engineering Applications

Authors: Irastorza-Lorenzo, Ainhoa, Sánchez-Porras, David, Ortiz-Arrabal, Olimpia, de Frutos, María José, Esteban, Emilio, Fernández, Javier, Janer, Agustín, Campos, Antonio, Campos, Fernando, Alaminos, Miguel

Contributors: Irastorza-Lorenzo,A, Sánchez-Porras,D, Ortiz-Arrabal,O, Campos,A, Campos,F, Alaminos,M Tissue Engineering Group, Department of Histology, University of Granada and Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain. de Frutos,MJ, Esteban,E, Fernández,J, Janer,A Hispanagar, SA, Burgos, Spain., This research was funded by grant IDI-20180052 (Agarmatriz), leaded by Hispanagar SA, Burgos, Spain, through CDTI, Ministry of Science and Innovation, Spain, Programa Operativo Plurirregional de Crecimiento Inteligente (CRIN), award no. AC17/00013 (NanoGSkin project) by ISCIII thorough AES 2017 within the EuroNanoMed framework, grant PE-0395-2019 from Consejería de Salud y Familias, Junta de Andalucía, Spain, and by the Spanish Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica (I+D+i) from Ministerio de Ciencia, Innovación y Universidades (Instituto de Salud Carlos III), grants FIS PI17/0391, and PI20/0317 (co-financed by Fondo Europeo de Desarrollo Regional ERDF-FEDER, European Union).

Subject Terms: Agarose, Tissue engineering, Biomaterials, Biocompatibility, Biomechanical properties, Sefarosa, Ingeniería tisular, Materiales biocompatibles, Análisis de materiales, Fenómenos biomecánicos, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Biomedical and Dental Materials::Biocompatible Materials, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Biophysical Phenomena::Biomechanical Phenomena, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival, Medical Subject Headings::Anatomy::Cells::Cells, Cultured, Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Elasticity::Elastic Modulus, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies, Medical Subject Headings::Persons::Persons::Volunteers::Healthy Volunteers, Medical Subject Headings::Chemicals and Drugs::Complex Mixtures::Colloids::Gels::Hydrogels, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Wistar, Medical Subject Headings::Organisms::Organism Forms::Aquatic Organisms::Seaweed, Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Polysaccharides::Sepharose, Medical Subject Headings::Anatomy::Integumentary System::Skin, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Prostheses and Implants::Tissue Scaffolds

File Description: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: https://www.mdpi.com/1422-0067/22/4/1923/htm; Irastorza-Lorenzo A, Sánchez-Porras D, Ortiz-Arrabal O, de Frutos MJ, Esteban E, Fernández J, et al. Evaluation of Marine Agarose Biomaterials for Tissue Engineering Applications. Int J Mol Sci. 2021 Feb 15;22(4):1923; http://hdl.handle.net/10668/4121; PMC7919481

Availability: http://hdl.handle.net/10668/4121
https://doi.org/10.3390/ijms22041923

Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre

Authors: Castejón-Vega, Beatriz, Battino, Maurizio, Quiles, José L., Bullon, Beatriz, Cordero, Mario D., Bullón, Pedro

Contributors: Castejón-Vega,B Research Laboratory, Dental School, University of Sevilla, Sevilla, Spain. Battino,M Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Sez. Biochimica, Università Politecnica delle Marche, Ancona, Italy. Battino,M International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang, China. Quiles,JL Department of Physiology, Institute of Nutrition and Food Technology “José Mataix”, Biomedical Research Center (CIBM), University of Granada, Armilla, Spain. Quiles,JL Research Group on Food, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, Santander, Spain. Bullon,B, Bullón,P Department of Periodontology, Dental School, University of Sevilla, Sevilla, Spain. Cordero,MD Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Cadiz, Spain. Cordero,MD Cátedra de Reproducción y Genética Humana del Instituto para el Estudio de la Biología de la Reproducción Humana (INEBIR)-Universidad Europea del Atlántico (UNEATLANTICO)-Fundación Universitaria Iberoamericana (FUNIBER), Santander, Spain., This research was funded by by a grant from the Andalusian regional government (Grupo de Investigacion Junta de Andalucia CTS113).

Subject Terms: Papillon–Lefèvre syndrome, Mitochondria, Coenzyme Q10, Enfermedad de Papillon-Lefevre, Mitocondrias, Ubiquinona, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cathepsins::Cathepsin C, Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Oxygen Compounds::Reactive Oxygen Species, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress, Medical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Periodontal Diseases::Periodontitis, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Topical, Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Oxygen Consumption, Medical Subject Headings::Technology and Food and Beverages::Food and Beverages::Food::Dietary Supplements, Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA::DNA, Circular::DNA, Mitochondrial

File Description: application/pdf

Relation: https://www.mdpi.com/2076-3921/10/1/95/htm; Castejón-Vega B, Battino M, Quiles JL, Bullon B, Cordero MD, Bullón P. Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre. Antioxidants (Basel). 2021 Jan 12;10(1):95; http://hdl.handle.net/10668/4019; PMC7827181

Availability: http://hdl.handle.net/10668/4019
https://doi.org/10.3390/antiox10010095

Cytotoxicity and Epidermal Barrier Function Evaluation of Common Antiseptics for Clinical Use in an Artificial Autologous Skin Model

Authors: Quiñones-Vico, María I., Fernández-González, Ana, Pérez-Castejón, Elena, Montero-Vílchez, Trinidad, Arias-Santiago, Salvador

Contributors: Quiñones-Vico,MI, Fernández-González,A, Pérez-Castejón,E, Arias-Santiago,S Cell Production and Tissue Engineering Unit, Virgen de las Nieves University Hospital, Granada, Spain. Quiñones-Vico,MI, Montero-Vílchez,T, Arias-Santiago,S Biosanitary Institute of Granada (ibs. GRANADA), Granada, Spain. Quiñones-Vico,MI, Arias-Santiago,S Andalusian Network of Design and Translation of Advanced Therapies, Sevilla, Spain. Quiñones-Vico,MI, Arias-Santiago,S Dermatology Department, School of Medicine, University of Granada, Granada, Spain. Montero-Vílchez,T, Arias-Santiago,S Dermatology Department, Virgen de las Nieves University Hospital, Granada, Spain., The work of María I. Quiñones Vico was supported by a predoctoral fellowship (BOE 22/10/2019) from the Ministry of Science, Innovation and Universities of Spain and by a researchinitiation grant of the University of Granada. This study is part of her doctoral research in the Biomedicine’s program of University of Granada. This study was funded by the Carlos III Health Institute of Spain through the project PI13/02576 and PI17/02083 (co-funded by European Regional Development Fund “A way to make Europe”) and Andalusian Regional Government Financial (SAS PI-0458-2016).

Subject Terms: Antiseptic/antibiotic testing, Bioengineered artificial skin substitute, Cell viability, Epidermal barrier function, Regenerative medicine, Wound healing, Antiinfecciosos locales, Piel artificial, Supervivencia celular, Células epidérmicas, Medicina regenerativa, Cicatrización de heridas, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Surgical Equipment::Artificial Organs::Skin, Artificial, Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Macrocyclic Compounds::Peptides, Cyclic::Polymyxins::Colistin, Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Polysaccharides::Glycosaminoglycans::Hyaluronic Acid, Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Sodium Compounds::Sodium Chloride, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Infective Agents, Local, Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Keratinocytes, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols, Medical Subject Headings::Anatomy::Tissues::Epithelium

File Description: application/pdf

Relation: https://www.mdpi.com/2077-0383/10/4/642/htm; Quiñones-Vico MI, Fernández-González A, Pérez-Castejón E, Montero-Vílchez T, Arias-Santiago S. Cytotoxicity and Epidermal Barrier Function Evaluation of Common Antiseptics for Clinical Use in an Artificial Autologous Skin Model. J Clin Med. 2021 Feb 8;10(4):642; http://hdl.handle.net/10668/4200; PMC7914612

Availability: http://hdl.handle.net/10668/4200
https://doi.org/10.3390/jcm10040642

Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria

Authors: Alvaro González‐Dominguez, Raúl Montañez, Beatriz Castejón‐Vega, Jéssica Nuñez‐Vasco, Débora Lendines‐Cordero, Chun Wang, Gabriel Mbalaviele, José M Navarro‐Pando, Elísabet Alcocer‐Gómez, Mario D Cordero

Contributors: [González-Dominguez,A, Montañez,R, Nuñez-Vasco,J, Lendines-Cordero,D, Cordero,MD] Instituto de Investigación e Innovación Biomédica de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain. [Castejón-Vega,B] Institute of Molecular, Cell and Systems Biology, University of Glasgow, Glasgow, UK. [Mbalaviele,G] Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO, USA. [Navarro-Pando,JM] Cátedra de Reproducción y Genética Humana del Instituto para el Estudio de la Biología de la Reproducción Humana (INEBIR), Universidad Europea del Atlántico (UNEATLANTICO)-Fundación Universitaria Iberoamericana (FUNIBER), Seville, Spain. [Alcocer-Gómez,E] Departamento de Psicología Experimental, Facultad de Psicología, Universidad de Sevilla, Sevilla, Spain., This study was supported by a grant from the Progeria Research Foundation PRF 2021- 80 grant, Andalusian regional government (Grupo de Investigacion Junta de Andalucia CTS113 and Consejer ıa de Salud de la Junta de Andalucia: PI-0036-2014). Dr. Gabriel Mbalaviele was supported by NIH/NIAMS AR068972 and AR076758 grants., Universidad de Sevilla. Departamento de Psicología Experimental, Junta de Andalucía

Source: EMBO Mol Med
RIUMA. Repositorio Institucional de la Universidad de Málaga
Universidad de Málaga
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-7 (2021)

Subject Terms: 0301 basic medicine, Medicine (General), Aging, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cysteine Proteases::Cysteine Endopeptidases::Caspases::Caspases, Initiator::Caspase 1, Inflamación (Patología), Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::Metabolism, Inborn Errors::Progeria, Inflammasomes, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Longevity, Envejecimiento, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Longevity, NLR Family, QH426-470, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Animal, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Mice, 03 medical and health sciences, R5-920, Progeria, Report, NLR Family, Pyrin Domain-Containing 3 Protein, Genetics, Animals, Humans, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::Nuclear Matrix-Associated Proteins::Lamins::Lamin Type A, 0303 health sciences, Animal, aging, Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation, Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal, progeria, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice, Lamin Type A, Pyrin Domain-Containing 3 Protein, NLRP3 inflammasome, 3. Good health, Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::Inflammasomes, Medical Subject Headings::Organisms::Eukaryota::Animals, Disease Models, Animal, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype, Disease Models, NLRP3inflammasome

File Description: application/pdf

Access URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/emmm.202114012
https://pubmed.ncbi.nlm.nih.gov/34448355
https://hdl.handle.net/10630/35316
http://hdl.handle.net/10668/4355
https://hdl.handle.net/11441/138040
https://eprints.gla.ac.uk/250961/1/250961.pdf
https://doaj.org/article/741ada3b7d4b430aadbd36423e7df82b
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https://www.embopress.org/doi/full/10.15252/emmm.202114012
https://hdl.handle.net/10668/4355
https://idus.us.es/handle//11441/138040

MitoBlue as a tool to analyze the mitochondria-lysosome communication

Authors: Sánchez, Mateo I., Vida, Yolanda, Pérez-Inestrosa, Ezequiel, Mascareñas, José L., Vázquez, M. Eugenio, Sugiura, Ayumu, Martínez-Costas, José

Contributors: Sánchez,MI, Mascareñas,JL, Vázquez,ME Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain. Sugiura,A Montreal Neurological Institute, McGill University, Montreal, QC, Canada. Sugiura,A Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada. Vida,Y, Pérez-Inestrosa,E Centro Andaluz de Nanomedicina y Biotecnología-BIONAND. Campanillas, Málaga, Spain. Martínez-Costas,J Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Bioquímica y Biología Molecular, Universidade de Santiago de Compostela, Santiago de, Compostela, Spain. Vida,Y, Pérez-Inestrosa,E Universidad de Málaga-IBIMA, Departamento de Química Orgánica, Málaga, Spain., The support was given by the Spanish grants BFU2013-43513-R, SAF2016-76689-R, CTQ2015-70698-R, RTI2018-099877-B-I00, CTQ2013-49317-EXP, CTQ2013-41339-P, CTQ2016-75870-P, CTQ2015-71896-REDT (Red de Fotoquímica Biológica) and Instituto de Salud Carlos III (ISCIII, RETIC ARADYAL D16/0006/0012), Junta de Andalucía (PI0250-2016 and UMA18-FEDERJA-007), Orfeo-cinqa network CTQ2016-81797-REDC, the Xunta de Galicia (2015-CP082, ED431C 2017/19, Centro Singular de investigación de Galicia accreditation 2019–2022, ED431G 2019/03), the European Union (European Regional Development Fund - ERDF), and the European Research Council (Advanced Grant No. 340055) are gratefully acknowledged. M.E.V. also acknowledges the support provided by the Fundación AECC IDEAS197VAZQ grant). A.S. was supported by the Uehara Memorial Foundation and a JSPS Postdoctoral Fellowship for Research Abroad.

Subject Terms: Mitochondrial degradation, Lysosome, Microscopy, Mitochondria, Proteins, Quality control, Mitofagia, Lisosomas, Microscopía, Mitocondrias, Proteínas, Control de calidad, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::2-Naphthylamine, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amidines, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Anatomy::Embryonic Structures::Embryo, Nonmammalian::Chick Embryo, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Lysosomes, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Microscopy::Microscopy, Fluorescence, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Laboratory Chemicals::Indicators and Reagents::Luminescent Agents::Fluorescent Dyes, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Histological Techniques::Histocytological Preparation Techniques::Staining and Labeling

File Description: application/pdf

Relation: https://www.nature.com/articles/s41598-020-60573-7; Sánchez MI, Vida Y, Pérez-Inestrosa E, Mascareñas JL, Vázquez ME, Sugiura A, et al. MitoBlue as a tool to analyze the mitochondria-lysosome communication. Sci Rep. 2020 Feb 26;10(1):3528; http://hdl.handle.net/10668/3856; PMC7044336

Availability: http://hdl.handle.net/10668/3856
https://doi.org/10.1038/s41598-020-60573-7

Canine colostrum exosomes: characterization and influence on the canine mesenchymal stem cell secretory profile and fibroblast anti-oxidative capacity

Authors: Villatoro, Antonio J., Martín-Astorga, María del Carmen, Alcoholado, Cristina, Becerra, José

Contributors: Villatoro,AJ, Martín-Astorga,MC, Alcoholado,C, Becerra,J Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain. Villatoro,AJ Instituto de Immunología Clínica y Terapia Celular (IMMUNESTEM), Málaga, Spain. Alcoholado,C, Becerra,J Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain. Becerra,J Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain., This work was partially supported by the Spanish Network on Cell Therapy (Red TerCel, RD16/0011/0022), Junta de Andalucía and University of Málaga. CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008–2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund.

Subject Terms: Canine colostrum milk, Mesenchymal stem cells, Exosomes, Dog, Anti-oxidative capacity, Calostro, Perros, Células madre mesenquimatosas, Exosomas, Antioxidantes, Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue, Medical Subject Headings::Organisms::Eukaryota::Animals, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Protective Agents::Antioxidants, Medical Subject Headings::Anatomy::Cells::Bone Marrow Cells, Medical Subject Headings::Anatomy::Cells::Cells, Cultured, Medical Subject Headings::Anatomy::Fluids and Secretions::Bodily Secretions::Colostrum, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Carnivora::Canidae::Dogs, Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Transport Vesicles::Exosomes, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Proteome

File Description: application/pdf

Relation: https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-020-02623-w; Villatoro AJ, Martín-Astorga MDC, Alcoholado C, Becerra J. Canine colostrum exosomes: characterization and influence on the canine mesenchymal stem cell secretory profile and fibroblast anti-oxidative capacity. BMC Vet Res. 2020 Nov 2;16(1):417; http://hdl.handle.net/10668/3600; PMC7607682

Availability: http://hdl.handle.net/10668/3600
https://doi.org/10.1186/s12917-020-02623-w

Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency

Authors: Fontán-Lozano, A., Capilla-Gonzalez, V., Aguilera, Y., Mellado, N., Carrión, A.M., Soria, B., Hmadcha, A.

Contributors: [Fontán-Lozano,A, Capilla-Gonzalez,V, Aguilera,Y, Mellado,N, Soria,B, Hmadcha,A] Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Sevilla, Spain. [Carrión,AM] División de Neurociencias, Universidad Pablo de Olavide de Sevilla, Sevilla, Spain. [Soria,B, Hmadcha,A] CIBER de Diabetes y Enfermedades Metabólica asociada (CIBERDEM), Madrid, Spain, This work was supported by a nonprofit foundation ‘Fundación Progreso y Salud’ of the Andalusian Regional Ministry of Health, Consejería de Innovación Ciencia y Empresa, Junta de Andalucía and Fondo Europeo de Desarrollo Regional (FEDER) (CTS-6505, INP-2011-1615-900000 and P10-CVI-6095), Instituto de Salud Carlos III and Fondo Europeo de Desarrollo Regional (FEDER) (RD12/0019/0028, PI10/00964 and PI14/01015), the Ministry of Health and Consumer Affairs (Advanced Therapies Program Grant TRA-120), Universidad de Sevilla. Departamento de Fisiología, European Commission, Junta de Andalucía, Fundación Progreso y Salud, Ministerio de Sanidad y Consumo (España), Ministerio de Educación y Ciencia (España), Instituto de Salud Carlos III

Source: RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Digital.CSIC. Repositorio Institucional del CSIC
Stem Cell Research, Vol 16, Iss 3, Pp 568-578 (2016)

Subject Terms: Pluripotency, 0301 basic medicine, Stage-Specific Embryonic Antigens, KChIP-3, QH301-705.5, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Human Embryonic Stem Cells, Down-Regulation, Real-Time Polymerase Chain Reaction, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, 03 medical and health sciences, Humans, Calsenilin, Biology (General), RNA, Small Interfering, Cyclic AMP Response Element-Binding Protein, Cells, Cultured, Medicine(all), CREB, DREAM, Medical Subject Headings::Anatomy::Cells::Stem Cells::Embryonic Stem Cells::Human Embryonic Stem Cells, Cell Differentiation, Kv Channel-Interacting Proteins, Cell Biology, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation, Fibroblasts, CREB-Binding Protein, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic-Leucine Zipper Transcription Factors::Cyclic AMP Response Element-Binding Protein, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Acyltransferases::Acetyltransferases::p300-CBP Transcription Factors::CREB-Binding Protein, Adipose Tissue, Differentiation, Antigens, Surface, Proteoglycans, RNA Interference, Human embryonic stem cells, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Stromal Cells::Mesenchymal Stromal Cells, Stromal Cells, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Calcium-Binding Proteins::Intracellular Calcium-Sensing Proteins::Neuronal Calcium-Sensor Proteins::Kv Channel-Interacting Proteins, Developmental Biology

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https://digital.csic.es/handle/10261/165227
https://hdl.handle.net/10668/2243

Novel (60%) and Recurrent (40%) Androgen Receptor Gene Mutations in a Series of 59 Patients with a 46,XY Disorder of Sex Development

Authors: Audi, L, Fernández-Cancio, M, Carrascosa, A, Andaluz, P, Torán, N, Piró, C, Vilaró, E, Vicens-Calvet, E, Gussinyé, M, Albisu, M A, Yeste, D, Clemente, M, Hernández de la Calle, I, Campo, M Del, Vendrell, T, Blanco, A, Martínez-Mora, J, Granada, M L, Salinas, I, Forn, J, Calaf, J, Angerri, O, Martínez-Sopena, M J, Valle, J Del, García, E, Gracia-Bouthelier, R, Lapunzina, P, Mayayo, E, Labarta, J I, Lledó, G, Sánchez Del Pozo, J, Arroyo, J, Pérez-Aytes, A, Beneyto, M, Segura, A, Borrás, V, Gabau, E, Caimarí, M, Rodríguez, A, Martínez-Aedo, M J, Carrera, M, Castaño, L, Andrade, M, Bermúdez de la Vega, J A

Contributors: Grupo de Apoyo al Síndrome de Insensibilidad a los Andrógenos (GrApSIA), [Audi,L, Fernández-Cancio,M, Carrascosa,A, Andaluz,P, Vilaró,E, Vicens-Calvet,E, Gussinyé,M, Albusi,MA, Yeste,D, Clemente,M] Pediatric Endocrinology Research Unit, Research Institute, Hospital Vall d’Hebron, Autonomous University, CIBERER (Centre for Biomedical Research Network on Rare Diseases), Instituto de Salud Carlos III, Barcelona, Spain. [Torán,N, Pirón,C, Hernandez de la Calle,I, Campo,M del, Vendrell,T] Departments of Pathology, Pediatric Surgery, Gynecology, and Genetics, Hospital Vall d’Hebron, Barcelona, Spain. [Blanco,A, Martínez-Mora,J, Granada,ML, Salinas,I] Departments of Pediatric Surgery, Biochemistry, and Endocrinology, Hospital Germans Trias-Pujol, Badalona, Spain. [Forn,J, Calaf,J] Departments of Pediatrics and Gynecology, Hospital Santa Creu i Sant Pau, Barcelona, Spain. [Angerri,O] Department of Urology, Fundació Puigvert, Barcelona, Spain. [Martínez-Sopena,MJ] Department of Pediatrics, Hospital Clínico, Valladolid, Spain. [Valle,J del, García,E] Department of Pediatric Endocrinology, Hospital Virgen del Rocío, Sevilla, Spain. [Gracia-Bouthelier,R, Lapunzina,P] Departments of Pediatric Endocrinology and Genetics, Hospital La Paz, Madrid, Spain. [Mayayo,E, Labarta,JI] Department of Pediatric Endocrinology, Hospital Infantil Miguel Servet, Zaragoza, Spain. [Lledó,G, Sánchez del Pozo,J] Department of Pediatric Endocrinology, Hospital 12 de Octubre, Madrid, Spain. [Arroyo,J] Department of Pediatrics, Complejo Hospitalario de Cáceres, Cáceres, Spain. [Pérez-Aytes,A] Department of Pediatrics, Hospital Infantil La Fe, Valencia, Spain. [Beneyto,M] Department of Genetics, Hospital La Fe, Valencia, Spain. [Segura,A] Department of Urology, Hospital General Universitario de Alicante, Alicante, Spain. [Borrás,V] Department of Pediatrics, Hospital de Granollers, Granollers, Spain. [Gabau,E] Department of Genetics, Corporació Hospitalaria Parc Taulí, Sabadell, Spain. [Caimarí,M] Department of Pediatrics, Hospital Son Dureta, Palma de Mallorca, Spain. [Rodríguez,A] Department of Pediatrics, Hospital Txagorritxu, Vitoria, Spain. [Martínez-Aedo,MJ] Department of Pediatric Endocrinology, Hospital Carlos Haya, Málaga, Spain.[Carrera,M] Centro de Patología Celular CPC, Barcelona, Spain. [Castaño,L] Research Institute, CIBERER, Instituto de Salud Carlos III, Hospital de Cruces, Bilbao, Spain. [Andrade,M] Department of Biochemistry, Hospital Xeral CIES, Vigo, Spain. [Bermúdez de la Vega,JA] Department of Pediatric Endocrinology, Hospital Virgen de la Macarena,Sevilla, Spain., This work was supported by grants from Instituto de Salud Carlos III, Madrid, Spain [PI06/0903 and CIBERER (Center for Biomedical Research on Rare Diseases)] and from AGAUR (University and Research Management and Evaluation Agency), Barcelona, Spain (SGR02 00042 and SGR05 00908).

Source: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Institut de Recerca Germans Trias i Pujol (IGTP)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Universitat Politècnica de Catalunya (UPC)
RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía
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Subject Terms: Male, 0301 basic medicine, Heterozygote, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Gene Components::Introns, Adolescent, Medical Subject Headings::Named Groups::Persons::Age Groups::Child::Child, Preschool, Sexual Behavior, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Sexual Behavior, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, 03 medical and health sciences, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Reverse Transcriptase Polymerase Chain Reaction, 0302 clinical medicine, 3-Oxo-5-alpha-Steroid 4-Dehydrogenase, 5. Gender equality, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Gene Components::Exons, Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Gonads::Testis, Testis, Medical Subject Headings::Named Groups::Persons::Age Groups::Infant, Humans, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-CH Group Donors::3-Oxo-5-alpha-Steroid 4-Dehydrogenase, Child, Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent, Gonadal Dysgenesis, 46,XY, Reverse Transcriptase Polymerase Chain Reaction, Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Congenital Abnormalities::Urogenital Abnormalities::Disorders of Sex Development::46, XY Disorders of Sex Development::Gonadal Dysgenesis, 46,XY, Infant, Medical Subject Headings::Named Groups::Persons::Age Groups::Child, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::Receptors, Cytoplasmic and Nuclear::Receptors, Steroid::Receptors, Androgen, Exons, Fibroblasts, Introns, 3. Good health, Medical Subject Headings::Check Tags::Male, Phenotype, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype, Receptors, Androgen, Child, Preschool, Mutation, Female, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Heterozygote

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Access URL: https://academic.oup.com/jcem/article-pdf/95/4/1876/10780752/jcem1876.pdf
https://pubmed.ncbi.nlm.nih.gov/20150575
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10090
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12781
http://hdl.handle.net/10668/1323
https://academic.oup.com/jcem/article/95/4/1876/2597320
https://academic.oup.com/jcem/article-pdf/95/4/1876/10780752/jcem1876.pdf
https://pubmed.ncbi.nlm.nih.gov/20150575/
https://www.repositoriosalud.es/handle/10668/1323
https://www.repositoriosalud.es/bitstream/10668/1323/1/AudiL_Novel60AndRecurrent.pdf
https://www.ncbi.nlm.nih.gov/pubmed/20150575
https://hdl.handle.net/10668/1323

Histological and histochemical evaluation of human oral mucosa constructs developed by tissue engineering

Authors: Sanchez-Quevedo, M.C., Alaminos, M., Capitan, L.M., Moreu, G., Garzon, I., Crespo, P.V., Campos, A

Contributors: Sanchez-Quevedo,MC, Alaminos,M, Garzon,I, Crespo,PV, Campos,A. Department of Histology, University of Granada, Spain. Alaminos,M Fundación Hospital Clínico, Granada, Spain. Capitan,LM Division of Oral and Maxillofacial Surgery, University Hospital Virgen de las Nieves, Granada, Spain. Moreu,G Department of Stomatology, University of Granada, Spain., This work was supported by the grants FIS 03/0141 and FIS 04/1306 from the Spanish National Ministry of Health (Instituto de Salud Carlos III) and by CM 2005/011 from Junta de Andalucia.

Subject Terms: Técnicas de Cultivo de Célula, Supervivencia Celular, Células Cultivadas, Microanálisis por Sonda Electrónica, Fibrina, Fibroblastos, Expresión Génica, Perfilación de la Expresión Génica, Humanos, Hidrogeles, Inmunohistoquímica, Queratinocitos, Microscopía Electrónica, Mucosa Bucal, Análisis de Secuencia en Orden de Oligonucleótido, Sefarosa, Ingeniería de Tejidos, Fibrin-agarose, Constructs, Tissue engineering, Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival, Medical Subject Headings::Anatomy::Cells::Cells, Cultured, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Microscopy::Microscopy, Electron::Electron Probe Microanalysis, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Fibrin, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts

File Description: application/pdf

Relation: http://www.hh.um.es/Abstracts/Vol_22/22_6/22_6_631.htm; Sanchez-Quevedo MC, Alaminos M, Capitan LM, Moreu G, Garzon I et al.Histological and histochemical evaluation of human oral mucosa constructs developed by tissue engineering. Histol Histopathol. 2007 Jun;22(6):631-40; http://hdl.handle.net/10668/683

Availability: http://hdl.handle.net/10668/683

Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis

Authors: Sanabria-de la Torre, Raquel, Fernández-González, Ana, Quiñones-Vico, María I., Montero-Vilchez, Trinidad, Arias-Santiago, Salvador

Contributors: Sanabria-de la Torre,R, Fernández-González,A, Quiñones-Vico,MI, Arias-Santiago,S Cell Production and Tissue Engineering Unit, Virgen de las Nieves University Hospital, Granada, Spain. Sanabria-de la Torre,R, Montero-Vilchez,T, Arias-Santiago,S Biosanitary Institute of Granada (ibs.GRANADA), Granada, Spain. Sanabria-de la Torre,R, Arias-Santiago,S Andalusian Network of Design and Translation of Advanced Therapies, Sevilla, Spain. Montero-Vilchez,T, Arias-Santiago,S Dermatology Department, Virgen de las Nieves University Hospital, Granada, Spain. Arias-Santiago,S Dermatology Department, School of Medicine, Granada University, Granada, Spain., We gratefully acknowledge financial support from Instituto de Salud Carlos III through the projects PI-13/02576 and PI-17/02083 (co-funded by European Regional Development Fund “A way to make Europe”) and Ministry of Health of the Andalusian Regional Government (SAS PI-0458-2016).

Subject Terms: Animal experimentation, Atopic dermatitis, Bioengineered artificial skin substitutes, Fibroblasts, Product testing, Psoriasis, Regenerative medicine, Tissue engineering, Keratinocytes, Transepidermal water loss, Experimentación animal, Dermatitis atópica, Fibroblastos, Ensayo de Materiales, Medicina regenerativa, Ingeniería de tejidos, Queratinocitos, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Animal Experimentation, Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Dermatitis::Dermatitis, Atopic, Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Materials Testing, Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Diseases, Papulosquamous::Psoriasis, Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Regenerative Medicine, Medical Subject Headings::Technology and Food and Beverages::Technology, Industry, and Agriculture::Engineering::Bioengineering::Cell Engineering::Tissue Engineering, Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Keratinocytes

File Description: application/pdf

Relation: https://www.mdpi.com/2227-9059/8/11/464/htm; Sanabria-de la Torre R, Fernández-González A, Quiñones-Vico MI, Montero-Vilchez T, Arias-Santiago S. Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis. Biomedicines. 2020 Oct 31;8(11):464; http://hdl.handle.net/10668/3703; PMC7694072

Availability: http://hdl.handle.net/10668/3703
https://doi.org/10.3390/biomedicines8110464