Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer

Authors: M. M. Tsyganov, M. K. Ibragimova, E. Yu. Garbukov, O. D. Bragina, E. A. Zdereva, E. A. Usynin, N. V. Litviakov

Source: Сибирский онкологический журнал, Vol 21, Iss 5, Pp 34-43 (2022)
Сибирский онкологический журнал. 2022. Т. 21, № 5. С. 34-43

Subject Terms: эффективность неоадъювантной химиотерапии, metastasis-free survival, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, efficacy of neoadjuvant chemotherapy, 03 medical and health sciences, breast cancer, 0302 clinical medicine, loss of heterozygosity, prognosis, явление потери гетерозиготности, рак молочной железы, безметастатическая выживаемость, RC254-282

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Access URL: https://doaj.org/article/b1f0d2902e8542369a6b0f4f9d059ac9
https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001008789

CORRELATION BETWEEN CHEMOTHERAPY RESPONSE AND EXPRESSION PROFILES OF TRANSMEMBRANE PROTEINS: P-GLYCOPROTEIN (ABCB1), MRP2 (ABCC2), BCRP (ABCG2) IN PATIENTS WITH INVASIVE BREAST CANCER ; СВЯЗЬ ЭФФЕКТИВНОСТИ ХИМИОТЕРАПИИ С ОСОБЕННОСТЯМИ ЭКСПРЕССИИ ТРАНСМЕМБРАННЫХ БЕЛКОВ P-ГЛИКОПРОТЕИНА (ABCB1), MRP2 (ABCC2), BCRP (ABCG2) У БОЛЬНЫХ ИНВАЗИВНЫМ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ

Authors: К. Yu. Khristenko, S. V. Vtorushin, М. V. Zavjalova, V. M. Perelmuter, К. Ю. Христенко, С. В. Вторушин, М. В. Завьялова, В. М. Перельмутер

Contributors: Президент Российской Федерации (грант МД-9084.2016.7 )

Source: Siberian journal of oncology; Том 15, № 4 (2016); 40-44 ; Сибирский онкологический журнал; Том 15, № 4 (2016); 40-44 ; 2312-3168 ; 1814-4861 ; 10.21294/1814-4861-2016-15-4

Subject Terms: лечебный патоморфоз, ABC-transporters, P-glycoprotein, MRP2, BCRP, breast cancer, pathologic response to neoadjuvant chemotherapy, ABC-транспортеры, P-гликопротеин, рак молочной железы, эффективность неоадъювантной химиотерапии

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Relation: https://www.siboncoj.ru/jour/article/view/383/359; Youlden D.R., Cramb S.M., Dunn N.A., Muller J.M., Pyke C.M., Baade P.D. The descriptive epidemiology of female breast cancer: an international comparison of screening, incidence, survival and mortality. Cancer Epidemiol. 2012 Jun; 36 (3): 237–48. doi:10.1016/j.canep.2012.02.007.; Gampenrieder S.P., Rinnerthaler G., Greil R. Neoadjuvant Chemotherapy and Targeted Therapy in Breast Cancer: Past, Present, and Future. J Oncol. 2013; 2013: 732047. doi:10.1155/2013/732047.; von Minckwitz G., Untch M., Loibl S. Update on neoadjuvant/preoperative therapy of breast cancer: experiences from the German Breast Group. Curr Opin Obstet Gynecol. 2013 Feb; 25 (1): 66–73. doi:10.1097/GCO.0b013e32835c0889.; Pluchino K.M., Hall M.D., Goldsborough A.S., Callaghan R., Gottesman M.M. Collateral sensitivity as a strategy against cancer multidrug resistance. Drug Resist Updat. 2012 Feb-Apr; 15 (1–2): 98–105. doi:10.1016/j.drup.2012.03.002.; Stavrovskaya A.A. Cellular mechanisms of multidrug resistance of tumor cells. Biochemistry (Mosc). 2000 Jan; 65 (1): 95–106.; Borst P., Evers R., Kool M., Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst. 2000 Aug 16; 92 (16): 1295–302.; Fukuda Y., Schuetz J.D. ABC transporters and their role in nucleoside and nucleotide drug resistance. Biochem Pharmacol. 2012 Apr 15; 83 (8): 1073–83. doi:10.1016/j.bcp.2011.12.042.; Kathawala R.J., Gupta P., Ashby C.R. Jr., Chen Z.N. The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade. Drug Resist Updat. 2015 Jan; 18: 1–17. doi:10.1016/j. drup.2014.11.002.; Wikens S. Structure and mechanism of ABC transporters. F1000Prime Rep. 2015 Feb 3;7:14. doi:10.12703/P7-14.; https://www.siboncoj.ru/jour/article/view/383

Availability: https://www.siboncoj.ru/jour/article/view/383
https://doi.org/10.21294/1814-4861-2016-15-4-40-44